Science Quiz / Rapid Review Step1 Classic Labs/Findings

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Can you name the Rapid Review Step1 Classic Labs/Findings

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Lab/Diagnostic FindingName/Diagnosis
heterophile antibodies
Anti-Glomerular Basment membrane antibodies
circular grouping of dark tumor cells surrounding pale neurofibrils
High D-Dimer
optochin resistant
Increased AFP in maternal serum/Amniotic fluid
anti-topoisomerase antibodies
optochin sensitive
Mamary gland blue domed cyst
Sheets of medium sized lymphoid cells with scattered pale tingible body0laden macrophages ('starry sky')
Hair on end crew cut appearance on xray
hypercoagulability leading to migrating superficial thrombophlembitis, DVTs, vasculitis…
nodular hyaline deposits in glomeruli
onion skin periosteal reaction
pANCA
monoclonal antibody spike, IgM
lead pipe appearance of colon on bariam enema xray
Anti-dsDNA
needle shaped, negatively birefringent crystals
necrotizing vasculitis in the lungs and necrotizing glomerulonephritis
podocyte fusion/effacement on EM
eosinophilic inclusion bodies in cytoplasm of hippocampal nerve cells
extracellular amyloid deposition in gray matter of brain
stippled vaginal epithelial cells
Anti-endymysial Antibodies
hexagonal, doublepointed, needle like crystals in bronchial secretions
anti-histone antibodies
renal epithelial casts in urine
glomerulus-like structure surrounding vessel in germ cells
Bacitracin Sensitive
thyroid like appearance of kidney
hilar lymphadenopathy, peripheral granulomatous lesion in middle or lower lungs, may be calcified
eosinophilic globule in liver
Hypertension, hypokalemia, metabolic alkalosis
protein aggregates in neurons from hyperphosphorylation of protein Tau
Yellow CSF
Anti-gliadin Antibodies
depigmentation of neurons in substantia nigra
giant B cells with bilobed nuclei with prominent inclusions ('owl's eye')
triglyceride accumulation in liver cell vacuoles
Lab/Diagnostic FindingName/Diagnosis
anti-IgG antibodies
Increased uric acid
cANCA
Basophilic stippling of RBCs
heart nodules (granulomatous)
hypochromic microcytic anemia
tennis racket shaped cytoplasmic organelles by EM in langerhan's cells
basophilic nuclear remnants in RBCs
iron-containing nodules in alveolar septum
 
colonies of mucoid pseudomonas in lungs
anti-transglutaminase Antibodies
monoclonal antibody spike, general
rectangular crystal-like cytoplasmic inclusions in Leydig Cells
Bamboo Spine on x-ray
degeneration of dorsal column nerves
weakly acid fast branching rods
bronchogenic apical lung tumor on imaging
cellular crescents in bowman's capsule
pseudopalisading tumor cells on brain biopsy
brown tumor of bone
silver staining spherical aggregation of tau proteins
rib notching
eosinophilic cytoplasmic inclusion in nerve cell
branching gram positive rods with sulfur granules (yellow)
thumb sign on lateral xray of neck
boot shaped heart on xray
Bacitracin Negative
thrombi made of white/red layers
keratin pearles on skin biopsy
large lysosomal vesicles in phagocytes
enlarged cells with intranuclear inclusion bodies
novobiocin sensitive
Azurophilic peroxidase positive granular inclusions in granulocytes and myeloblasts
Anticentromere Antibodies
elevated hCG but not pregnant
ANCAs
liniear IgG deposition on glomerular basement membrane
intranuclear eosinophilic droplet like bodies
wire loop clomerular capillary appearance on LM
Lab/Diagnostic FindingName/Diagnosis
nutmeg liver
novobiocin resistant
monoclonal antibody spike, IgA or IgG
disarrayed granulosa cells in eosinophilic fluid
polished, ivorylike appearance of bone at cartilage erosion
narrowing of bowel lumen on barium xray
Anti-Smith
soap bubble in femor or tibia on xray
Antidesmoglein (epithelial) antibodies
mucin filled cell with peripheral nucleus
enlarged thyroid cells with ground glass nuclei
low serum ceruloplasmin
bloody tap on LP
periosteum raised from bone, creating triangular area
ring enhancing brain lesion in AIDs
Anti-Nuclear Antibody (ANA)
lytic hole punch bone lesions on xray
eosinophilic cytoplasmic inclusion in LIVER cell
spikes on BM and dome like subepithelial deposits
cardiomegaly with apical atrophy
RBC casts in urine
WBC casts in urine
honeycomb lung on xray or CT
decreased AFP in maternal serum/amniotic fluid
apple core lesion on abdominal xray
antiplatelet antibodies
Calcified whorls on histo
Hypersegmented neutrophils
smudge cells (WBCs)
desquamated epithelium casts in sputum
lumpy bumpy appearance of glomeruli on immunofluorescence
antimitochondrial antibodies (AMA)
tramtrack appearance of capillary loops of glomerular basement membrane on LM
waxy casts with low urine flow
dysplastic squamous cervical cells with nuclear enlargement and hyperchromasia
rhomboid crystals, positively birefringent
stacks of RBCs
chocolate cyst of ovary

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