Science Quiz / MNE Dr. Kasid's Material

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Can you name the hormones, receptors, and vocabulary words of Dr. Kasid's lectures?

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HintAnswer
What activity of a G-protein does Cholera toxin disrupt?
PKA is a protein kinase that phosphorylates at which residues?
In the smooth muscle of the heart or blood vessels, cytosolic guanylyl cyclase is activated by this compound.
GEF (guanine exchange factor) proteins enhance the dissociation of what molecule from Ras?
The huge number of glucose molecules, for example, that are liberated by a single molecule of insulin upstream in the pathway is an example of what?
Steroid hormones are able to diffuse through the lipid bilayer because they are:
True or False: RTK's produce cAMP as a second mesenger.
The first line of defense against viral inefections involves this system.
True or False: PLC an PI-3K can be regulated by both GPCR's and RTK's.
Membrane-bound guanylyl cyclase is activated by either guanylin or this compound.
GRB2is one protein of a pair that links RTK to Ras; what is the other?
How many cAMP molecules are required to free PKA from its regulatory subunit complex?
In a patient with Cholera toxin, what compound is being constitutively produced?
Which type of receptor would cause heart rate to increase?
What is the precursor of both IP3 and DAG called?
The specificity of a STAT protein is determined in its _____________ domain.
Phosphorylation of glycogen phosphorylase kinase and glycogen phosphorylase will deactivate these two enzymes; what protein accomplishes this?
In the RTK-Ras pathway, what protein acts as a GEF?
Where in the body can alpha adrenergic receptors be found?
CAPK is a more descriptive term for which protein?
Activated JAK proteins catalyze phosphorylation of receptors; phosphorylated tyrosine on such a receptor serves as a docking site for these proteins.
HintAnswer
What molecule closely associates with cytosolic guanylyl cyclase?
What is the ultimate precursor for epinephrine?
Which type of receptor would cause bronchial dilation after binding its ligand?
Atrial Natriuretic Factor (ANF) binds to and activates this receptor.
The defective oncogenic form of the EGF receptor is called:
Alpha 2 adrenergic receptors use which G-protein?
Alpha 1 adrenergic receptors use which G-protein?
Vasoconstriction is accomplished through activation of _____ adrenergic receptors
Leptin receptors use the ________ pathway for downstream signaling.
The appropriate term for an attractive older man who, despite his age, is desired by younger women.
Calcium inhibits which upstream enzyme by negative feedback?
Pertussis toxin affects the alpha subunit of Gi, preventing it from releasing which compound?
Neuromuscular junctions exhibit which type of ACh receptor?
Increases in cytosolic levels of IP3 and DAG are associated with Gq activating which protein?
True or False: there is normally a tonic, or basal, level of second messengers present in the cytosol.
Cyclic AMP can be deactivated through cleavage carried out by which enzyme that is inhibited by caffeine?
All beta adrenergic receptors associate with this G-protein type.
Myristoylphorbol acetate is a tumor promotor because it enhances cell growth and proliferation through activation of which compound?
All of the following will have epinephrine binding to the Gs beta adrenergic receptors EXCEPT: liver, adipose, intestine, CNS, skeletal muscle.
Phosphorylation of the Gs receptor by PKA causes which compound to bind and sequester it further?

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