Science Quiz / MNE Dr. Kasid's Material

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Can you name the hormones, receptors, and vocabulary words of Dr. Kasid's lectures?

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HintAnswer
All of the following will have epinephrine binding to the Gs beta adrenergic receptors EXCEPT: liver, adipose, intestine, CNS, skeletal muscle.
Alpha 1 adrenergic receptors use which G-protein?
True or False: there is normally a tonic, or basal, level of second messengers present in the cytosol.
The huge number of glucose molecules, for example, that are liberated by a single molecule of insulin upstream in the pathway is an example of what?
True or False: PLC an PI-3K can be regulated by both GPCR's and RTK's.
The first line of defense against viral inefections involves this system.
All beta adrenergic receptors associate with this G-protein type.
Phosphorylation of the Gs receptor by PKA causes which compound to bind and sequester it further?
In the smooth muscle of the heart or blood vessels, cytosolic guanylyl cyclase is activated by this compound.
Where in the body can alpha adrenergic receptors be found?
Activated JAK proteins catalyze phosphorylation of receptors; phosphorylated tyrosine on such a receptor serves as a docking site for these proteins.
CAPK is a more descriptive term for which protein?
What molecule closely associates with cytosolic guanylyl cyclase?
Which type of receptor would cause bronchial dilation after binding its ligand?
The defective oncogenic form of the EGF receptor is called:
True or False: RTK's produce cAMP as a second mesenger.
Membrane-bound guanylyl cyclase is activated by either guanylin or this compound.
Leptin receptors use the ________ pathway for downstream signaling.
PKA is a protein kinase that phosphorylates at which residues?
The appropriate term for an attractive older man who, despite his age, is desired by younger women.
Alpha 2 adrenergic receptors use which G-protein?
HintAnswer
How many cAMP molecules are required to free PKA from its regulatory subunit complex?
In the RTK-Ras pathway, what protein acts as a GEF?
In a patient with Cholera toxin, what compound is being constitutively produced?
Atrial Natriuretic Factor (ANF) binds to and activates this receptor.
Cyclic AMP can be deactivated through cleavage carried out by which enzyme that is inhibited by caffeine?
Vasoconstriction is accomplished through activation of _____ adrenergic receptors
Increases in cytosolic levels of IP3 and DAG are associated with Gq activating which protein?
What is the ultimate precursor for epinephrine?
GRB2is one protein of a pair that links RTK to Ras; what is the other?
Calcium inhibits which upstream enzyme by negative feedback?
What activity of a G-protein does Cholera toxin disrupt?
Neuromuscular junctions exhibit which type of ACh receptor?
What is the precursor of both IP3 and DAG called?
Pertussis toxin affects the alpha subunit of Gi, preventing it from releasing which compound?
GEF (guanine exchange factor) proteins enhance the dissociation of what molecule from Ras?
Phosphorylation of glycogen phosphorylase kinase and glycogen phosphorylase will deactivate these two enzymes; what protein accomplishes this?
Myristoylphorbol acetate is a tumor promotor because it enhances cell growth and proliferation through activation of which compound?
Which type of receptor would cause heart rate to increase?
The specificity of a STAT protein is determined in its _____________ domain.
Steroid hormones are able to diffuse through the lipid bilayer because they are:

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