Science Quiz / MCB 4211 Final

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Can you name the MCB 4211 Final?

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Toxic molecule which may be conjugated to an Ab against tumor Ag
A reaction consisting of mixing two cell populations and observing proliferation via radiolabeled DNA incorporation
Camera used in immunodiagnosis of cancer with radioactive anti-tumor Abs
Complex which mediates siRNA cleavage of targer sequence
Test which may be used to diagnose HIV
A single heavy chain antibody which spontaneously forms and Ag binding pocket, very stable
Tumor rejection is primarily a _____ T-Cell respons
Cleaves target mRNA in a sequence specific manner
MHC Class I genes, which are codominant
Cytokine receptor which is a coreceptor for HIV
Proccess in which blood is removed from the patient, centrifuged, replaced w/o immune cytokines
Type III Hypersensitivity Reactions are due to the formation of ________
A failure to maintain self tolerance
Type IV Hypersensitivities are mediated by _______ which secrete ______
Genes which affect traits in an analog manner
A method of treating autoimmune disease which interferes with protein-protein interactions
A carcinoma with an embryonal carcinoma in its center
CD4+ T-cells secrete this cytokine after engaging an APC in tumor rejection
Neoplasia which de-differentiates; invasive
Receptor which interacts with HIV
Term for overhelming of T-cells with self antigen, causing anergy of autoreactive cell
The defective protein in nude mice, leading to a failure in thymic development
Hypothesis which suggested that the immune system eliminated most tumors
Main Site of damage due to Type III Hypersensitivity Reaction
Neoplasia which maintains a differentiated state
Surface Markers of T-reg Cells
A common cytokine receptor, the lack of which prevents B and T cell signalling activity
A defect in granule management leading to defective NK/Mast Cells, equivalent to beige mice
A defect in MHC Class I or II production
CD4+ Cell surface marker which internalizes upon binding, allowing for siRNA internalizing
The human equivalent of nude mice
A single gene defect causes this disorder, with a SLE phenotype
Term for maintainence of self-tolerance in tissues with few naive T-cells
Phenotype resulting from injecting apoptosis-treated thymus into syngenic mice
A tyrosine phosphotase/proto-oncogene
Autoimmune disorder directed against self DNA
The single gene defect in GLD is present in this molecule or its receptor
Tolerance created by negative selection in the thymus
An infection derived from an animal
Enzyme which integrates viral HIV DNA into human genome at random
Interacts with Immunophilins, Active T cells expressing NF-AT
Mice used as humanized mouse models
Surface proteins of HIV
Maps phenotype versus genetic markers
A kinase which assosciates with zeta upon TcR engagement/proto-oncogene
Assay which tests for carcinogenicity
Two common HIV treatments which only protect uninfected cells, as infected cells no longer need reverse transcriptase
A lymphocyte acttivated outside the body and re-inserted to kill tumors
Toxic molecule which alkylates DNA, interfering with immune capacity
Dandruff causing fungus
Heritable Immunodeficiencies
The proccess of isolating autoreactive t cells and injecting them to create a B-cell/T-reg response
Virus which may be cross-reactive with insulin receptors
Cells which supress autoimmune disease

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