Science Quiz / MCB 4211 Final

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Can you name the MCB 4211 Final?

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Dandruff causing fungus
Enzyme which integrates viral HIV DNA into human genome at random
Heritable Immunodeficiencies
Test which may be used to diagnose HIV
Mice used as humanized mouse models
A reaction consisting of mixing two cell populations and observing proliferation via radiolabeled DNA incorporation
Toxic molecule which may be conjugated to an Ab against tumor Ag
A defect in MHC Class I or II production
An infection derived from an animal
A common cytokine receptor, the lack of which prevents B and T cell signalling activity
A defect in granule management leading to defective NK/Mast Cells, equivalent to beige mice
Phenotype resulting from injecting apoptosis-treated thymus into syngenic mice
Tumor rejection is primarily a _____ T-Cell respons
Receptor which interacts with HIV
A single gene defect causes this disorder, with a SLE phenotype
Two common HIV treatments which only protect uninfected cells, as infected cells no longer need reverse transcriptase
Genes which affect traits in an analog manner
Term for overhelming of T-cells with self antigen, causing anergy of autoreactive cell
Hypothesis which suggested that the immune system eliminated most tumors
A method of treating autoimmune disease which interferes with protein-protein interactions
The single gene defect in GLD is present in this molecule or its receptor
Cells which supress autoimmune disease
A tyrosine phosphotase/proto-oncogene
Toxic molecule which alkylates DNA, interfering with immune capacity
A failure to maintain self tolerance
The defective protein in nude mice, leading to a failure in thymic development
Cytokine receptor which is a coreceptor for HIV
CD4+ Cell surface marker which internalizes upon binding, allowing for siRNA internalizing
Tolerance created by negative selection in the thymus
Complex which mediates siRNA cleavage of targer sequence
Type III Hypersensitivity Reactions are due to the formation of ________
Maps phenotype versus genetic markers
Assay which tests for carcinogenicity
CD4+ T-cells secrete this cytokine after engaging an APC in tumor rejection
Term for maintainence of self-tolerance in tissues with few naive T-cells
Surface proteins of HIV
Autoimmune disorder directed against self DNA
The proccess of isolating autoreactive t cells and injecting them to create a B-cell/T-reg response
Surface Markers of T-reg Cells
The human equivalent of nude mice
Camera used in immunodiagnosis of cancer with radioactive anti-tumor Abs
Type IV Hypersensitivities are mediated by _______ which secrete ______
Neoplasia which maintains a differentiated state
MHC Class I genes, which are codominant
Virus which may be cross-reactive with insulin receptors
Interacts with Immunophilins, Active T cells expressing NF-AT
Cleaves target mRNA in a sequence specific manner
A carcinoma with an embryonal carcinoma in its center
Proccess in which blood is removed from the patient, centrifuged, replaced w/o immune cytokines
Main Site of damage due to Type III Hypersensitivity Reaction
A lymphocyte acttivated outside the body and re-inserted to kill tumors
A kinase which assosciates with zeta upon TcR engagement/proto-oncogene
Neoplasia which de-differentiates; invasive
A single heavy chain antibody which spontaneously forms and Ag binding pocket, very stable

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