Science Quiz / MCB 4211 Final

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Can you name the MCB 4211 Final?

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ClueTerm
Dandruff causing fungus
A defect in MHC Class I or II production
Heritable Immunodeficiencies
A reaction consisting of mixing two cell populations and observing proliferation via radiolabeled DNA incorporation
Cytokine receptor which is a coreceptor for HIV
A tyrosine phosphotase/proto-oncogene
Interacts with Immunophilins, Active T cells expressing NF-AT
Surface Markers of T-reg Cells
CD4+ T-cells secrete this cytokine after engaging an APC in tumor rejection
The human equivalent of nude mice
Proccess in which blood is removed from the patient, centrifuged, replaced w/o immune cytokines
Two common HIV treatments which only protect uninfected cells, as infected cells no longer need reverse transcriptase
 
A method of treating autoimmune disease which interferes with protein-protein interactions
Main Site of damage due to Type III Hypersensitivity Reaction
Cleaves target mRNA in a sequence specific manner
A defect in granule management leading to defective NK/Mast Cells, equivalent to beige mice
Autoimmune disorder directed against self DNA
Neoplasia which de-differentiates; invasive
A lymphocyte acttivated outside the body and re-inserted to kill tumors
Enzyme which integrates viral HIV DNA into human genome at random
An infection derived from an animal
Complex which mediates siRNA cleavage of targer sequence
Term for maintainence of self-tolerance in tissues with few naive T-cells
Mice used as humanized mouse models
Neoplasia which maintains a differentiated state
The defective protein in nude mice, leading to a failure in thymic development
Toxic molecule which may be conjugated to an Ab against tumor Ag
ClueTerm
A single heavy chain antibody which spontaneously forms and Ag binding pocket, very stable
Tolerance created by negative selection in the thymus
Type IV Hypersensitivities are mediated by _______ which secrete ______
Type III Hypersensitivity Reactions are due to the formation of ________
A carcinoma with an embryonal carcinoma in its center
Toxic molecule which alkylates DNA, interfering with immune capacity
Assay which tests for carcinogenicity
Camera used in immunodiagnosis of cancer with radioactive anti-tumor Abs
Phenotype resulting from injecting apoptosis-treated thymus into syngenic mice
The proccess of isolating autoreactive t cells and injecting them to create a B-cell/T-reg response
Term for overhelming of T-cells with self antigen, causing anergy of autoreactive cell
Maps phenotype versus genetic markers
A single gene defect causes this disorder, with a SLE phenotype
Test which may be used to diagnose HIV
A failure to maintain self tolerance
A common cytokine receptor, the lack of which prevents B and T cell signalling activity
The single gene defect in GLD is present in this molecule or its receptor
A kinase which assosciates with zeta upon TcR engagement/proto-oncogene
Genes which affect traits in an analog manner
Tumor rejection is primarily a _____ T-Cell respons
MHC Class I genes, which are codominant
Receptor which interacts with HIV
Virus which may be cross-reactive with insulin receptors
Cells which supress autoimmune disease
CD4+ Cell surface marker which internalizes upon binding, allowing for siRNA internalizing
Hypothesis which suggested that the immune system eliminated most tumors
Surface proteins of HIV

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