Science Quiz / More Viruses

Random Science Quiz

QUIZ: Can you name the More Viruses?

Quiz not verified by Sporcle

Forced Order
Also try: Venomous Animals
Challenge
Share
Tweet
Embed
Score 0/63 Timer 15:00
HintVirusExtra
NS2 induces change in gene expression
Surface glycoprotein HBsAgNeutralises antibodies
Entry uses E1 and E2
Soluble cytokine receptors
Resistant to low pH and protease
Hep - Drugs>Vaccine
NS2/NS3 proteases
Cancer - cervical or penile
Shed in concs of 10^9 pfu/ml
Block transport of peptides into ERDecreases CTL action
Cancer - nasopharyngeal
Stimulate cell into cell cycle
sGP with immunomodulatory functionAlso reduces antibody count
Cytopathic effect
Gag, pol and envGag 1st, Pol frameshift, Env splicing
Buds through cell membrane
Lacks env proteinRequires co-infection with helper, src instead
MHC - proteolytic degradationRemains largely cell-associated (like measles)
Retains MHC intracellularlyMay result in NK missing self
Expressed EGF to improve adjacent cellsInduces hypoxic response - biochem reactions
10^6 mutant viruses produced/day
HintVirusExtra
Virions formed by internal budding into ER
Enters by gp340 binding to CD21
Virus clearance requires seroconversion
Dane particles (42nm) and lipoproteins (22nm)
Binds to sialic acid with HAHA is a trimer
DNA with Virion transcriptaseTranscription of viral promoters
Proteins produced from one reading frameLater polyprotein processing
Cleave mRNA caps
VG35 Inhibits IRF3 and binds dsRNADecreases IFNa/b release
Cancer - Burkitt lymphoma
Systemic infection
Acute and chronic hepatitis
Very stable outside the host
Destroys ribosome cap-binding complexShuts off host protein synthesis in an hour (IRES)
Capsid (p24) with envelope (gp41, gp120)Gp120 binds CD4 and CCR5/CXCR4
Inhibits JAK-STAT pathway
Incubation, pre-haemorrhagic and haemorrhagic
Temporally distinct gene classesPox - early, intermediate, late
VP24 blocks STAT1 entering nucleusBinds nuclear pore proteins
Inhibit ISG proteinsPKR, OAS
Expressed viral IL-10
HintVirusExtra
Asymptomatic for ~10 years
Soluble cytokine receptors
Cancer - Kaposi's sarcoma
Infects cerebellar Purkinje cells
Latency
Can grow in macrophages
Capsid assembles spontaneouslyHelical capsid
3.2kb genome4 reading frames
Produce dNTPs
Infects liver macrophages (Kupffer)
Carried by biting insects
Hep - Vaccine>Drugs
Antigenic shift and drift
Soluble IFNa/b binding proteins
Acute hepatitis
High frequency genetic recombination
ZoonoticHarder to eliminate, less herd immunity
Cancer - hepatocellular
Bullet-shaped
Prevent activation of PRR cascadeDecreases IFN gamma
Down-regulate CD4 and inhibit NFkBVpu and Vpr proteins

You're not logged in!

Compare scores with friends on all Sporcle quizzes.
Sign Up with Email
OR
Log In

You Might Also Like...

Show Comments

Extras

Top Quizzes Today


Score Distribution

Your Account Isn't Verified!

In order to create a playlist on Sporcle, you need to verify the email address you used during registration. Go to your Sporcle Settings to finish the process.