Science Quiz

Random Science Quiz

DNA replication, mutation and repair revision Quiz Stats

 Plays Quiz not verified by Sporcle

Challenge
Share
Tweet
Embed
Score 0/93 Timer 10:00
0 Plays Today
Questions Answer % Correct
Daughter strands are produced from parent strands where?replication fork
40%
The formation of telomeres is catalysed by the enzyme...telomerase
40%
Adenine deamination causes the product to base pair with...cytosine
40%
Which enzyme separates the DNA into two strands?Helicase
35%
The lagging strand contains...okazaki fragments
30%
The strand within which there is no lag is called...the leading strand
30%
DNA polymerase posses which correction enzyme to check if a wrong nucleotide is present?exonuclease
30%
exonuclease moves in which direction?3' to 5'
30%
When a single base is changed it is called a...point mutation
30%
DNA synthesis commences in which phase?S phase
25%
What is the direction of DNA synthesis?5' to 3'
25%
What prevents the loss of the ends of chromosomes after a round of replication?telomeres
25%
When a single code in the triplet code is altered and the causing the amino acid to change this is known as a...missense mutation
25%
In sickle cell the amino acid glutamic acid becomes..valine
25%
Cytosine deamination causes the product to base pair with...adenine
25%
Which molecule extends the primers with DNA from 5' to 3'DNA polymerase III
20%
Which molecule removes RNA primers and replaces it with DNA on both strands?DNA polymerase I
20%
Which molecule is used to prevent supercoiling?topoisomerase
20%
in which direction does telomerase work?5' to 3'
20%
When the last base of the triplet code is changed, unaltering the amino acid it is known as...a silent mutation
20%
another name for a silent mutation is called a...synonymous mutation
20%
An example of a gross level deletion mutation is...Cri du chat syndrome
20%
cytosine is deaminated to... uracil
20%
A symptom of XP is extreme sensitivity to sunlight by the age of...2
20%
What is primase?An RNA polymerase
15%
Unwinding the double helix in one region causes coiling in another, what is this known as?positive supercoiling
15%
Supercoiling causes...mechanical stress
15%
Which molecule fills in the gaps between adjacent okazaki fragments?DNA ligase
15%
What is the distance (in bases) between each replication origin in eukaryotes?150 kilobases
15%
Another name for the hayflick limit?senescence
15%
what percentage of all human primary tumor test positive for telomerase activity?85%
15%
Questions Answer % Correct
sickle cell is an example of a...missense mutation
15%
If an indel keeps the DNA code a multiple of three then there is...a maintenance of the reading frame
15%
Due to a frame shift the...reading frame is lost
15%
Chronic myelogenous leukaemia occurs when pieces of...resulting in the philidelphia chromosomechromosome 9 and 22 swap
15%
An example of direct repair removing foreign methyl groups is..Dealkylation by enzymes
15%
Which type of UV light is absorbed by the ozone layer?UV-C
15%
Which type of UV light is mutagenic?UV-B
15%
In which part of the cell cycle does protein synthesis occur?Gap phase 1
10%
In which phase are the duplicated copies of DNA separated and prepared for mitosis?Gap phase 2
10%
Which protein is used to prevent the single strand DNA rejoining by stabilising it?single strand binding protein
10%
Where do SSB's sit?under the helicase enzyme
10%
What is the final error rate in DNA?1 in 10^10 bases are wrong
10%
How many replication origins to circular bacterial chromosomes have?1
10%
Why must the end replication paradox not occur?important DNA may be lost and all DNA must be passed on to progeny
10%
telomerase is a type of...DNA polymerase
10%
Why does telomerase not need a chromosomal template?It carries its own RNA template
10%
A non-synonymous mutation is called a...missense mutation
10%
A nonsense mutation is when an amino acid triplet code is mutated into a...stop codon
10%
small scale insertion and small scale deletions are known as...indels
10%
Cystic fibrosis occurs due to a deletion of which gene508th
10%
Indels generally do not have major impact on health when they occur in an...intron region
10%
Cri du chat syndrome caused by the...deletion of the end of chromosome 5
10%
Reverse slippage is caused by the...insertion of repeats
10%
Deamination is...from a moleculethe removal of an amine group
10%
molecules which fit into spaces between base pairs causing replication errors are known as...intercalating agents
10%
DNA damage is repaired via...direct repair and removal
10%
reverse transcriptase is a type of...DNA polymperase
10%
A reverse transcriptase inhibiter that was used before but became obsolete due to the high RNA mutation rate was... Azedothymidine
10%
Semi conservative replication means each DNA molecule contains...one parent and one daughter strand
5%
Where do helices enzymes act?origin of replication
5%
What forms when helicase unwinds DNA?two replication forks
5%
Questions Answer % Correct
DNA polymerase will only begin synthesis at...3' end of the template strand
5%
Which molecule is used to prompt DNA replication?primase
5%
How many replication orgins do eukaryotic chromosomes have?multiple
5%
replication happens...in both eukaryotes and prokaryotesbi-directionally
5%
Ends of linear chromosomes being lost after each round of replication is known as the...end replication paradox
5%
What is the hayflick limit?when cell division stops
5%
Which cells do not grow old and have no reproductive limit?cancer cells
5%
huntington's disease is more likely if there are more than 10-34 (36-121) of which codon and amino acidCAG and glutamine
5%
Mutations appear in our genomes due to...spontaneous and induced mutations
5%
Errors in DNA replication, replication slippage and deamination are examples of...spontaneous mutation
5%
Adenine is deaminated to...Hypoxanthine
5%
Physical induced mutation includes...ionizing radiation and uv light
5%
An example of direct repair which removes damaged DNA and resynthesises it is...Nucleotide excision repair
5%
defective nucleotide excision repair of UV damage can lead to...xeroderma pigmentosum
5%
an example of NER mutation for UV damage is the mutation in...which encodes for a helices required for NERXP-D
5%
Reverse transcriptase can't proofread because...it does not have a 3' to 5' exonuclease
5%
primers are no longer than...14 nucleotides
0%
Topoisomerase...to relieve pressure of supercoilingbreaks one 5' to 3' phosphodiester bond
0%
What is unusual about telomerase?it extends DNA without using a chromosomal template
0%
When N-RAS mutates its amino acid Gln becomes...histidine
0%
If an index is not a multiple of three after an index a...occursframe shift
0%
indwells generally do have a major impact on human health when they occur in an....exon region
0%
Gross mutations include...inversions,deletions,duplications and translocations
0%
An example of gross mutation, translocation is...Chronic myelogenous leukaemia
0%
Individual who are homozygous of the...in the CCR5 allele are resistant to HIV I32nd base pair
0%
CCR5 codes for the.... that is also the co-receptor for HIV Ichemokine receptor
0%
Errors in DNA replication occur due to the...escape from proofreading
0%
forward slippage is caused by the...deletion of repeats
0%
Uv light causes..to formthymine dimers
0%
ionizing radiation causes....to breaksingle or double strands
0%
Chemically physical induced mutations are caused by...reagents that react with bases
0%

You're not logged in!

Compare scores with friends on all Sporcle quizzes.
Join for Free
OR
Log In

You Might Also Like...

Show Comments

Extras

Top Quizzes Today


Score Distribution

Your Account Isn't Verified!

In order to create a playlist on Sporcle, you need to verify the email address you used during registration. Go to your Sporcle Settings to finish the process.

Report this User

Report this user for behavior that violates our Community Guidelines.

Details: