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Protein structure revision Quiz Stats

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Questions Answer % Correct
Which structure of a protein sees the folded peptide chains joining together?Quaternary
81.3%
What are the two types of protein, in terms of structure?Fibrilar
37.5%
H-bond donors include...Nitrogen and Oxygen
34.4%
Hydrophilic groups are generally found on the....of proteinsoutside
28.1%
Proteins with high amount of alpha helix are usually...globular
28.1%
The C-terminal is also known as the...Carboxyl terminus
25%
The R-groups face the....when an alpha helix formsoutside
25%
A triple helix has... residues per turn?3
25%
The first amino acid is known as the N-terminal end because it contains an... groupNH3+
21.9%
Sickle cell is caused by a mutation of the...amino acidGlu
21.9%
Which type of bonding occurs between peptides and other polar groupr?hydrogen bonding
18.8%
Disulphide bridges occur between...2 cysteine amino acids
18.8%
Which amino acid is consistently present in an triple helixglycine
18.8%
Due to rigidity the C-N bond shows no...stereoisomerism
15.6%
What is odd about that C-N bond?It is shorter than expected
15.6%
in a peptide the N atom is...partially positive
15.6%
In a peptide the O atom is...partially negative
15.6%
A H-bond acceptor is an...atomoxygen
15.6%
What is the physiological pH range?7.3-7.5
15.6%
The NH3+ group can be found in which amino acids?Lys & Arg
12.5%
The O-H bond can be found on the side chains of which amino acids?Ser, Thr, Tyr
12.5%
The enthalpy change for the H-bond is...12 kjmol-3
12.5%
What is d/2 equivalent to?VDW radius of an atom
12.5%
Denaturation is caused by?pH, tempreature, ionic strength
12.5%
A characteristic of the anti parallel beta sheet is...the hairpin bend
12.5%
In which beta pleated sheet formation will you find loops?parallel Beta sheet
12.5%
The triple helix is a.... helix unlike the alpha helixleft handed
12.5%
Beta barrels, beta sandwiches and Rossman folds are a types of...super secondary structures
12.5%
short polypeptide consist of about...amino acids10-40
12.5%
Polymerisation of PrPsc forms...fibrils
12.5%
Which amino acid is present in a sickle cell Hb, that would not be in a normal functioning Hb?Val
12.5%
The sickle cell mutation causes Hb to change from being charged to...hydrophobic
12.5%
Hydrophobic groups are generally found on the inside of a protein due to...the hydrophobic effect
9.4%
Questions Answer % Correct
A triple covalently bonded nitrogen can act as...A H-bond acceptor
9.4%
A triple covalently bonded nitrogen can be found in which amino acids?Trp & His
9.4%
The N-H bond can be found in which amino acids?Trp, His & Arg
9.4%
What is the length of the Hydrogen bond?0.28
9.4%
The side chains of which amino acids, containing -COOH are ionised at physiological pH?Asp, Glu
9.4%
The side chains of which amino acids, containing -NH3 are ionised at physiological pH?Gln, Asn
9.4%
A protein has thousands of possible structures, how many of these are functional?1
9.4%
in an alpha helix there are...residues per turn3.6
9.4%
Which secondary structure has H-bonds between peptide chains?Beta pleated sheets
9.4%
In which naturally occurring molecule is the triple helix found?collagen
9.4%
Hb has...% alpha helix60
9.4%
Glucagon (29aa's) is...a peptide hormone
9.4%
Super secondary structures are... of alpha helices and beta pleated sheetscombinations
9.4%
Aspartame is made up of which amino acids?asp, phe
9.4%
In Alzheimers disease which proteins form plaques?Amyloid proteins
9.4%
In CJD, PrPc changes to...PrPsc
9.4%
H- bonds that form the alpha helix are found every....peptide4th
6.3%
Which type of beta pleated sheet formation is widely found in globular proteins?anti parallel B sheet
6.3%
Large polypeptides consist of... amino acids40 +
6.3%
The polymerisation of which proteins leads to Creutzfeldt Jakob disease?Prion protein
6.3%
PrPsc forms beta pleated sheets where as the normal form of prion protein forms....Alpha helices
6.3%
PrPsc is resistant to...unlike PrPcproteolysis
6.3%
The....shape of the helix provides architectural supportcylindrical
3.1%
The distance between each turn in an alpha helix is...0.45 nm
3.1%
Proline and hydrox-yproline can be found where?in the collagen triple helix
3.1%
Dystrophin is an example of a...large protein
3.1%
neurotransmitters are...short polypeptides
3.1%
Aggregated prions are...neurotoxic
3.1%
Which part of the Hb molecule is affected in sickle cell disease?Beta-6 subunit
3.1%
The primary sequence of amino acids define....of a proteinstructure, function
0%
The H-bonds which form the alpha helix are found...in the same polypeptide chain
0%
Proteins with a high amount of B pleated sheets are usuallyfibrilar protiens
0%
Glutathione is made up of which amino acids?Glu, cys, gly
0%

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Created Dec 15, 2014ReportNominate
Tags:protein, revision, structure

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