Science Quiz / Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
Jock Rot 'well demarcated line'
Serology is great and should ALWAYS be followed
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
Pseudo membrane in oropharynx - thrush.
Intracellular fungus, Spelunking, prisons, chicken coops
Never use this for diagnosis of cryptococcus
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
Apical lung fungal ball
right angle hyphae
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Parental drug addict mucormycosis
Bone fungal infections
Serology is terrible and is often false positive for histoplasmosis
Bone marrow recipients/leukemic pts. mucormycosis
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
When in serum grows pseudohyphae. Retinal presentations
Tx for Zygomycetes
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Strain of cryptococcus that hits immunecompromised
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
Fungal infection causing baldness
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Ubiquitous with hyphae branching at acute angles
Distal finger nail infection
QuestionAnswerAdditional information
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Risk factor for yeast infection
Narrow base budding
Athletes foot
candida strain resistant to azoles
prophylaxis for pneumocystis and toxoplasmosis
Diabetic mucormycosis
Arizona/mexico border, Confussion/meningitis
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Dx stain for Cryto
diaper rash
Immunecompromised w/ old dressings or IVs mucormycosis
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
HIV Finger nail infection
Fungal infection that runs along lymphatic vessel. Rose growers disease
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Ring worm
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
HIV, Thailand, Red pigment
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Bind to fungal heme iron in cytochrome P-450
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Tx for cryptococcus meningitis (Abv.)
Massive laryngeal mass causing obstruction - South americam agricultural worker
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Strain of cryptococcus on the west coast and hits non-immuncompromised
Dose dependent Candida strain
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia

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