Science Quiz / Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
HIV, Thailand, Red pigment
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
HIV Finger nail infection
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Apical lung fungal ball
Bind to fungal heme iron in cytochrome P-450
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Pseudo membrane in oropharynx - thrush.
Risk factor for yeast infection
Narrow base budding
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Bone fungal infections
Fungal infection causing baldness
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
prophylaxis for pneumocystis and toxoplasmosis
Serology is great and should ALWAYS be followed
right angle hyphae
Strain of cryptococcus that hits immunecompromised
Ubiquitous with hyphae branching at acute angles
Dose dependent Candida strain
Never use this for diagnosis of cryptococcus
Diabetic mucormycosis
Immunecompromised w/ old dressings or IVs mucormycosis
Intracellular fungus, Spelunking, prisons, chicken coops
Tx for cryptococcus meningitis (Abv.)
candida strain resistant to azoles
QuestionAnswerAdditional information
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Distal finger nail infection
When in serum grows pseudohyphae. Retinal presentations
Athletes foot
Jock Rot 'well demarcated line'
Bone marrow recipients/leukemic pts. mucormycosis
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
diaper rash
Ring worm
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
Dx stain for Cryto
Fungal infection that runs along lymphatic vessel. Rose growers disease
Tx for Zygomycetes
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Strain of cryptococcus on the west coast and hits non-immuncompromised
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Parental drug addict mucormycosis
Massive laryngeal mass causing obstruction - South americam agricultural worker
Serology is terrible and is often false positive for histoplasmosis
Arizona/mexico border, Confussion/meningitis

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