Science Quiz / Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
Diabetic mucormycosis
Risk factor for yeast infection
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Serology is terrible and is often false positive for histoplasmosis
Never use this for diagnosis of cryptococcus
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Bone marrow recipients/leukemic pts. mucormycosis
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
HIV, Thailand, Red pigment
Ubiquitous with hyphae branching at acute angles
Dx stain for Cryto
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Apical lung fungal ball
diaper rash
Tx for cryptococcus meningitis (Abv.)
Bind to fungal heme iron in cytochrome P-450
Dose dependent Candida strain
Fungal infection that runs along lymphatic vessel. Rose growers disease
Bone fungal infections
Distal finger nail infection
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
QuestionAnswerAdditional information
Arizona/mexico border, Confussion/meningitis
Narrow base budding
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Athletes foot
Serology is great and should ALWAYS be followed
When in serum grows pseudohyphae. Retinal presentations
Pseudo membrane in oropharynx - thrush.
Immunecompromised w/ old dressings or IVs mucormycosis
HIV Finger nail infection
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
Intracellular fungus, Spelunking, prisons, chicken coops
Ring worm
Fungal infection causing baldness
right angle hyphae
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Massive laryngeal mass causing obstruction - South americam agricultural worker
Strain of cryptococcus on the west coast and hits non-immuncompromised
candida strain resistant to azoles
Tx for Zygomycetes
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
prophylaxis for pneumocystis and toxoplasmosis
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Jock Rot 'well demarcated line'
Parental drug addict mucormycosis
Strain of cryptococcus that hits immunecompromised

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