Science Quiz / Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
Never use this for diagnosis of cryptococcus
Fungal infection causing baldness
Massive laryngeal mass causing obstruction - South americam agricultural worker
Fungal infection that runs along lymphatic vessel. Rose growers disease
Strain of cryptococcus that hits immunecompromised
Tx for Zygomycetes
Pseudo membrane in oropharynx - thrush.
Bind to fungal heme iron in cytochrome P-450
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
right angle hyphae
Diabetic mucormycosis
Tx for cryptococcus meningitis (Abv.)
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
Immunecompromised w/ old dressings or IVs mucormycosis
Serology is terrible and is often false positive for histoplasmosis
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
Ring worm
Narrow base budding
Bone fungal infections
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Intracellular fungus, Spelunking, prisons, chicken coops
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
diaper rash
candida strain resistant to azoles
Jock Rot 'well demarcated line'
Strain of cryptococcus on the west coast and hits non-immuncompromised
Arizona/mexico border, Confussion/meningitis
QuestionAnswerAdditional information
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Parental drug addict mucormycosis
Ubiquitous with hyphae branching at acute angles
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
HIV, Thailand, Red pigment
Athletes foot
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Risk factor for yeast infection
When in serum grows pseudohyphae. Retinal presentations
Serology is great and should ALWAYS be followed
prophylaxis for pneumocystis and toxoplasmosis
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Bone marrow recipients/leukemic pts. mucormycosis
Distal finger nail infection
Dose dependent Candida strain
HIV Finger nail infection
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Dx stain for Cryto
Apical lung fungal ball
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.

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