Science Quiz / Infectious Disease Block 6 - Fungus

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QUIZ: Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Tx for Zygomycetes
Apical lung fungal ball
Dose dependent Candida strain
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Ubiquitous with hyphae branching at acute angles
Strain of cryptococcus that hits immunecompromised
right angle hyphae
Serology is terrible and is often false positive for histoplasmosis
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Athletes foot
Parental drug addict mucormycosis
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Arizona/mexico border, Confussion/meningitis
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Tx for cryptococcus meningitis (Abv.)
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
Intracellular fungus, Spelunking, prisons, chicken coops
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
Fungal infection that runs along lymphatic vessel. Rose growers disease
Never use this for diagnosis of cryptococcus
Jock Rot 'well demarcated line'
Dx stain for Cryto
Bone marrow recipients/leukemic pts. mucormycosis
QuestionAnswerAdditional information
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Immunecompromised w/ old dressings or IVs mucormycosis
Distal finger nail infection
Diabetic mucormycosis
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
When in serum grows pseudohyphae. Retinal presentations
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
candida strain resistant to azoles
Strain of cryptococcus on the west coast and hits non-immuncompromised
Risk factor for yeast infection
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
Massive laryngeal mass causing obstruction - South americam agricultural worker
HIV, Thailand, Red pigment
Narrow base budding
Fungal infection causing baldness
Serology is great and should ALWAYS be followed
Bone fungal infections
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
HIV Finger nail infection
Bind to fungal heme iron in cytochrome P-450
Pseudo membrane in oropharynx - thrush.
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
diaper rash
Ring worm
prophylaxis for pneumocystis and toxoplasmosis
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions

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