Science Quiz / Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
Tx for cryptococcus meningitis (Abv.)
Tx for Zygomycetes
Arizona/mexico border, Confussion/meningitis
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Fungal infection causing baldness
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.
Dose dependent Candida strain
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
When in serum grows pseudohyphae. Retinal presentations
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
Parental drug addict mucormycosis
HIV, Thailand, Red pigment
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Strain of cryptococcus that hits immunecompromised
Strain of cryptococcus on the west coast and hits non-immuncompromised
Ubiquitous with hyphae branching at acute angles
prophylaxis for pneumocystis and toxoplasmosis
Immunecompromised w/ old dressings or IVs mucormycosis
Athletes foot
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
diaper rash
Massive laryngeal mass causing obstruction - South americam agricultural worker
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Fungal infection that runs along lymphatic vessel. Rose growers disease
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Serology is great and should ALWAYS be followed
QuestionAnswerAdditional information
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Apical lung fungal ball
Distal finger nail infection
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
HIV Finger nail infection
right angle hyphae
Ring worm
candida strain resistant to azoles
Bind to fungal heme iron in cytochrome P-450
Serology is terrible and is often false positive for histoplasmosis
Never use this for diagnosis of cryptococcus
Risk factor for yeast infection
Dx stain for Cryto
Narrow base budding
Bone marrow recipients/leukemic pts. mucormycosis
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
Diabetic mucormycosis
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
Intracellular fungus, Spelunking, prisons, chicken coops
Pseudo membrane in oropharynx - thrush.
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Bone fungal infections
Jock Rot 'well demarcated line'
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology

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