Science Quiz / Infectious Disease Block 6 - Fungus

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Can you name the Infectious Disease Block 6?

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QuestionAnswerAdditional information
Drug with multiple double bonds and intercalates into fungal plasma membranes creating lytic pores
Broad base budding, In soil. Great lakes. Beavers. Hits Normal immune systems. Fisherman, campers, hunters
Fungal infection that runs along lymphatic vessel. Rose growers disease
MCC of fungal meningitis in AIDS pts. Pidgeon poop.
candida strain resistant to azoles
Antifungal drug whose mechanism is similar to that of penicillin to bacteria. Tx for candida and aspergillus.
DNA synthesis inhibitor. Goes to the CNS. Can Cause hemorrhagic colitis and pancytopenia
Ring worm
Tx for Zygomycetes
Strain of cryptococcus that hits immunecompromised
Rapid O2 desaturation upon exertion. Life threatening pneumonia in AIDS. Ubiquitous
Dx stain for Cryto
Bone marrow recipients/leukemic pts. mucormycosis
Anti-fungal with Side effects of adrenal Insufficiency and hepatic necrosis. Needs gastric acid for absorption
When in serum grows pseudohyphae. Retinal presentations
right angle hyphae
Bind to fungal heme iron in cytochrome P-450
Apical lung fungal ball
HIV Finger nail infection
Drug addict, diabetic w/ ketoacidosis, Bone transplant recipient, Renal Failure. Black necrosis of the ororpharynx. Rapid presentation
Pseudo membrane in oropharynx - thrush.
Anti-fungal with 3 fluorides. Tx for aspergillus. S/E - Bone pain, alteration in electroretinogram, increased alkaline phos, periostitis, Visual scatoma. Multiple drug interactions
Skinny white male with COPD gets this fungal infection. pneumoia pericarditis, adrenal disease, adenocarcinoma like bowel lesions
Verrucous/warty skin lesions in cooler areas (tip of nose, fingers)
diaper rash
Dose dependent Candida strain
Massive laryngeal mass causing obstruction - South americam agricultural worker
Risk factor for yeast infection
QuestionAnswerAdditional information
Parental drug addict mucormycosis
Ubiquitous with hyphae branching at acute angles
Diabetic mucormycosis
Halo sign, wedge shaped pulmonary emboli infarct, immune compromised
Narrow base budding
Low Alkaline phosphatase, LDH less than 300, Leukocytopenia. Diagnosed via urine serology
Arizona/mexico border, Confussion/meningitis
Tx for histoplasmosis, spirotrichosis, and blastomyces. Taken with food/coca cola. Side effects: Adrenal excess (edema, hypertension, hypokalemia) nausea, vomiting. Long term - per
prophylaxis for pneumocystis and toxoplasmosis
Treats ring worm and nail infections. Inhibits nucleic acid synthesis
Serology is terrible and is often false positive for histoplasmosis
Jock Rot 'well demarcated line'
Strain of cryptococcus on the west coast and hits non-immuncompromised
HIV, Thailand, Red pigment
Intracellular fungus, Spelunking, prisons, chicken coops
Fungal infection causing baldness
Antifungal to treat fungal UTI's and has CSF penetration. Great pharmacokinetics.Treats coccidioides.
Side effects are: Shake and Bake (fever chills, headache, nausea, vomiting) mediated through release of prostaglandin E. Renal toxicity is closely watched.
Never use this for diagnosis of cryptococcus
Athletes foot
Immunecompromised w/ old dressings or IVs mucormycosis
Serology is great and should ALWAYS be followed
Distal finger nail infection
Tx for cryptococcus meningitis (Abv.)
Bone fungal infections
erythema nodosum, hilar adenopathy. Apical cavitary disease. Dark skin and pregnancy are risk factors. Meningitis = Tx for life
Drug that is concentrated in the skin. Side effect is a loss of taste. Effective against dimorphic fungi in nails and skin
Need to suppliment with potassium, magnesium and EPO because of its renal toxicity.

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