Miscellaneous Quiz / Thera2-ThromboembolicDrugs

Random Miscellaneous Quiz

Can you name the Thera2-AnticoagulantDrugs?

Quiz not verified by Sporcle

Forced Order
Challenge
Share
Tweet
Embed
Score 0/69 Timer 20:00
HintAnswer
Monitoring parameters of Warfarin are: prothrombin time and ____
Enoxaparin is indicated for the treatment & prophylaxis of DVT/PE and acute MI/_____ angina.
UFH inactivates factors: ___ (most), X, IX, XI, and XII.
T or F: 2C9 & 3A4 inhibitors and decreased vitamin K DECREASE the effect of warfarin.
UFH prophylactic dosing is: _____ units SQ every 8-12 hours.
T or F: Argatroban is given as a continuous IV infusion and requires dose adjustment for hepatic impairment.
Fondaparinux is used for prophylaxis & treatment of DVT/PE, ACS, and ___ (not FDA approved)
Brand Name Enoxaparin
Warfarin inhibits vitamin K _______ reductase.
Treatment dose of Fondaparinux for a patient < 50kg is: ___mg
Treatment dose of Fondaparinux for a patient weighing > 100kg is: ___mg
Phytonadione Brand Name
Brand Name Fondaparinux
UFH treatment dosing is: ___units/kg bolus followed by 18 units/kg/hour.
T or F: Patient education regarding enoxaparin should include teaching the patient how to inject the drug.
The goal aPTT for UFH therapy is ___-___. (enter as # - #)
T or F: Enoxaparin inhibits factor II more than factor X.
T or F: Phytonadione (Vitamin K analog) is an antidote to warfarin.
Argatroban is indicated for HIT or ____
Heparin's antidote
Argatroban might cause a false elevation in INR of __-__ points. (enter as # - #)
T or F: If a patient experiences HIT I on UFH therapy, stop the treatment stat.
Treatment dose of Fondaparinux for a patient weighing 50-100kg is: ___mg
HintAnswer
Normal prothrombin time is __-__ seconds (enter as # - #)
T or F: Fondaparinux has more thrombocytopenia than LMWH.
UFH toxic monitoring includes: bleeding complications and ___ every other day x 2 weeks or until stopped
When using Enoxaparin, anti-Xa should be monitored if the patient is _____, pregnant, or has renal insufficiency.
Lepirudin is indicated for ____ treatment in HIT patients.
Warfarin also interferes with endogenous anticoagulant proteins ___ & S.
Enoxaparin's starting TREATMENT dose is: ___mg/kg SQ BID or 1.5mg/kg daily.
T or F: Enoxaparin requires dose adjustment in renal impairment.
Warfarin dosing is: initiate __mg PO after UFH or LMWH initiated.
Lepirudin, Argatroban, and Dabigatran all work by directly inhibiting _______.
Warfarin's S-isomer is metabolized by CYP450 ___.
Warfarin works by interfering with _______ synthesis of vitamin K dependent clotting factors.
Warfarin interferes with clotting factors: ___, ___, ___, and ___. (enter in order of longest to shortest time; separate answers by commas))
Side effects of Dabigatran are bleeding and _________.
Brand Name UFH
T or F: UFH treatment doses are given as a continuous IV.
Enoxaparin's starting PROPHYLACTIC dose is: ___mg SQ BID or 40mg SQ daily.
Dabigatran dosing is: ___mg PO BID.
Some side effects of Enoxaparin include: bleeding, thrombocytopenia, and ____ at the injection site.
T or F: Fondaparinux treatment dosing is weight based.
Dabigatran dosing in renal impairment (CrCl 15-30mL/min) is ___mg PO BID
Possible side effects of Warfarin include: bleeding, ____ necrosis, and purple toe syndrome.
Normal INR is __-__ (enter as # - #)
HintAnswer
When on Lepirudin, ____ should be monitored every 4 hours until stable.
T or F: Cholestyramine interferes with warfarin absorption.
Fondaparinux works through anti-___a activity only.
T or F: UFH therapeutic uses include: prophylaxis & treatment of DVT/PE, acute coronary syndromes, and atrial fibrillation.
T or F: Warfarin is approved for prophylaxis & treatment of DVT/PE, acute MI, prosthetic heart valves, atrial fibrillation, and inherited clotting disorders.
Enoxaparin works by enhancing the activity of _____.
Dabigatran is indicated for: ____ ____
Side effects of UFH therapy include: bleeding, _________, HIT I, HIT II, and osteopenia.
Brand Name Dabigatran
T or F: Direct thrombin inhibitors have a reversal agent.
Toxic monitoring parameters of Enoxaparin include: ____ and signs of bleeding.
T or F: If a patient experiences HIT II on UFH therapy, stop treatment immediately.
T or F: Possible drug interactions with Dabigatran include p-glycoprotein inhibitors or inducers, e.g. PPIs and antacids.
Fondaparinux monitoring may include: ___
T or F: Fondaparinux administration might produce injection site reactions.
Lepirudin's dose is given as a ______ infusion.
Warfarin's R-isomer is metabolized by CYP450 3A4 & ___
Brand Name Warfarin
Fondaparinux prophylactic dosing is: ___mg SQ every 24 hours
Brand Name Lepirudin
UFH works by binding to ______, converting it from a slow inhibitor to a rapid inhibitor of thrombin.
UFH therapeutic monitoring for treatment doses includes: ___
UFH target patients include all except: (a) immobile (b) post-op (c) trauma (d) spinal cord injuries (e) all of the above are target patients.

You're not logged in!

Compare scores with friends on all Sporcle quizzes.
Sign Up with Email
OR
Log In

You Might Also Like...

Show Comments

Extras

Top Quizzes Today


Score Distribution

Your Account Isn't Verified!

In order to create a playlist on Sporcle, you need to verify the email address you used during registration. Go to your Sporcle Settings to finish the process.