Pilocarpine
Increases outflow of aqueous humor
Miosis
Cholinergic Crisis is a side effect
Blurred vision, burning, tearing also AE
Contraindicated with recent myocardial infarction
Also CI with unstable angina or severe arrhythmia
Induction of cycloplegia
Also induces mydriasis
What to watch for with atropine
Also watch for urinary retention, constipation, dry mouth
Atropine contraindicated with
Also CI with glaucoma, asthma, benign prostatic hypertrophy, paralytic ileus
Used to treat motion sickness
Treatment of asthma, COPD, rhinitis
Inhalation therapy
Located in the heart
Also located in kidney
Located in the lungs
Also uterus, liver, GI
Located in the blood vessels
Also located in smooth muscle
Epinephrine
Also used for cardiac arrest, AV block, acute wheezing
CI with pregnancy
Also CI with glaucoma, severe cardiac,
Cannot give epinephrine this route
With epinephrine monitor for
Check for sulfite sensitivity also
Used to be OTC but now behind counter due to Illegal synthesis of methamphetamines
OTC bronchodilator and decongestant
Use for severe hypotension or cardiac arrest
Strong Alpha Stimulation, but does not stimulate beta-2
Phenlyephrine (Neo-synephrine) used for
Also used for hypotension, shock (vascular failure), and with anesthesia
Alpha-1 adrenergic agonist
Used to prevent symptoms of drug detox
Side effects: dry mouth, drowsiness, dizziness, constipation
Occurs if clonidine is stopped suddenly
Must correct this first with Dopamine (Intropin)
Given by IV infusion and has a rapid onset where it needs to be tapered off to avoid hypotension
Stimulates dopaminergic, beta-1, alpha-1 receptors
Dopamine used for which surgery
Also used for hypotension, shock, renal failure
Dopamine (Intropin) dependent on
Do not mix dopamine (intropin) with
Caution with occlusive vascular disease
Treatment of extravasation with this drug
Sub-Q injection; also used with Raynaud's and pheochromocytoma
This drug is used for cardiac decompression from dilated cardiomyopathy
Increases contractility and only given through IV
Symptoms of Sulfite Sensitivity
Also symptoms of loss of consciousness, dizziness, hypotension, SOB, respiratory distress, syncope
Alpha-Adrenergic Antagonists
Used for Vasodilation, relaxation of bladder neck, muscle/prostate
Take first dose of these at bedtime
take note to change positions slowly, cool down after exercise, avoid alcohol, avoid driving,
Decreases heart rate, myocardial contractility, av conduction time
Used to treat hypertension, angina/MI, atrial & ventricular arrythmia, compensated heart failure, hyperthyroidism, migranes, stage fright, glaucoma, essential tumors
Do not give in severe bradycardia, AV heart block, shock, heart failure uncompensated, asthma, COPD,
Black box warning - do not stop suddenly; will worsen angina or MI
Before giving beta blocker
Combined blocker
Combined alpha and beta blocker