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Wong - Male Physiology
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______ Reaction: Ovum is initially surrounded by several layers of granulosa cells (corona radiata). Sperm must penetrate these layers to access and fuse with ovum.
______ Insensitivity Syndrome: Individuals are Genetic Males XY, but individuals possess a 'Normal' Female Phenotype.
In the absence of testicular actions, female reproductive structures develop by default from the ________ ducts.
Sperm viability is highly affected by _____
In humans, testes are first distinguishable within ____ weeks of gestation and become fully functional by week 7-16.
_______ pattern of GnRH: essential for normal sperm and testosterone production.
_____: Fetal roles incude differentiation of external genital structures and testicular descent.
______: A type of glycosaminoglycan. It cuts a path to the ovum where its head fuses with the oocyte membrane and releases its genetic material to cause fertilization.
DHT action must be initiated within Week _____ of gestation.
_____: Condition in which one or both testes fail to descend into scrotum during development
Elevated temperatures suppress _______ through destruction of spermatogonia
Defects in _______ typically impair either sperm motility or the ability of the sperm to penetrate the ovum.
Normalizing plasma testosterone in primary hypogonadism fails to restore fertility because systemic plasma levels remain too low to restore adequate sperm _______ and maturation wi
Sperm ______: includes washing away of inhibitory factors and weakening of the sperm head.
Normal range of sperm count is ______ million/ml
Female sexual differentiation is normally completed between Week ______ of gestation (a little later than males)
______: Mediated by efferent sympathetic stimulation. Ejection of sperm and semen to exterior or into the female reproductive tract.
_______: Forms a sticky coagulant, which retains sperm within the female tract
_______ tubules: site of spermatogenesis. Primordial germ cells located near basement membrane.
_____: A glycoprotein that is stimulated in response to increased FSH stimulation of Sertoli cells. It exerts negative feedback by regulating FSH release from anterior pituitrary.
_____: An important protein induced in Sertoli cells by FSH. It binds and concentrates Testosterone within Seminiferous tubules.
______: Function is to optimally maintain testes temperature to 2 degrees less than body temperature.
PSA and Profibrinolysin dissolve the _________ to release the sperm to facilitate motility and migration within the female tract.
_______: Enhance sperm motility and may stimulate uterine reverse peristalsis facilitating sperm migration through the fallopian tubes to the ovum.
______: Involved in suppressing sperm metabolism and activity prior to ejaculation. Allows sperm to survive for a long time in males.
Sperm survival in the female reproductive tract is typically _____ days.
Name a site of sperm storage.
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