| Description | Answer |
| Only Oscar-winning film to exceed 400 minutes | |
| Only President to not be elected | |
| Only animal that hunts in prides | |
| Only world capital that starts with Q | |
| Only MLB team to never be in the playoffs | |
| Only band to have 20 or more #1 hits | |
| Only thing that can kill Superman | |
| Only continent without an island nation** | |
| Only TV episode that got more than 50 million viewers* | |
| Only Element that starts with X | |