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| Oakland Raiders' first overall pick in the 2007 NFL Draft | |
| Taken second overall in the 2003 NBA Draft by the Detroit Pistons, right after LeBron James and right before Carmelo Anthony | |
| Drafted #1 overall by the Washington Wizards in the 2001 NBA Draft straight out of high school | |
| Drafted #1 overall by the San Diego Padres in the 2004 MLB Draft | |
| Drafted #1 overall by the Cleveland Browns in the 1999 NFL Draft | |
| First round selection of the Kansas City Chiefs in the 1983 NFL Draft, failed to live up to standard set by other quarterbacks taken in the same draft such as John Elway and Dan Ma | |
| The Cincinnati Bengals selected him #1 overall in the 1995 NFL Draft | |
| Taken 4th overall by the Baltimore Colts in the 1982 NFL Draft, career derailed by gambling problems | |
| Drafted in the first round of the 1999 NFL Draft by the Chicago Bears | |
| Drafted 6th overall by the New York Jets in the 2008 NFL Draft | |
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| First overall pick of the 2002 NFL Draft by the Houston Texans, holds the record for most times being sacked in a single season at 76 | |
| #3 overall pick of the 2002 NFL Draft by the Detroit Lions | |
| Drafted #2 overall in the 1984 NBA Draft, right after Hakeem Olajuwon and right before Michael Jordan | |
| Drafted #2 overall by the San Diego Chargers in the 1998 NFL Draft | |
| 1st overall selection in the 2007 NBA Draft by the Portland Trail Blazers | |
| Drafted 1st overall by the Pittsburgh Pirates in the 2002 MLB Draft | |
| Taken by the Green Bay Packers with the #2 pick in the 1989 NFL Draft, immediately after Troy Aikman and immediately before Barry Sanders | |
| 3rd overall pick of the 1999 NFL Draft taken by the Cincinnati Bengals | |
| Selected in the 1987 NFL Supplemental Draft by the Seattle Seahawks, also know as 'The Boz' | |
| Drafted #3 overall in the 2006 NBA draft by the Charlotte Bobcats | |
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