The open road was a metaphor for freedom for three bikers bucking American sociopolitical norms in this 1969 movie.

Dan Aykroyd and John Belushi as two brothers on an open-road mission to reunite their band and make $5K to save their childhood orphanage.

Woody Harrelson and Juliette Lewis as two characters on a highway killing spree in this 1994 Oliver Stone film.

David Duchovny as a writer and Carrie Laughlin his girlfriend who make a bad mistake when they pick up hitchhikers played by Brad Pitt and Juliette Lewis.

Geena Davis as a passive housewife and Susan Sarandon a single waitress who go on an interstate crime spree in this 1991 film.

The adventures of Clark Griswold and family on their way to Wallyworld, this 1983 classic.

Burt Reynolds as a savvy decoy, Jerry Reed as a bootlegging truck driver, Sally Field a runaway bride and Jackie Gleason, the hapless law in this 1977 film.

Kurt Russell and Kathleen Quinlan as man and wife who are being stalked and tormented by a vicious group of road thugs in this 1997 thriller.

Patrick Swayze is a truck driver just released from prison for vehicular manslaughter blackmailed into hauling a load of illegal weapons for Meat Loaf's character.

Robert DeNiro is a bounty hunter transporting a man (Chas. Grodin) who embezzled $15 million from the Chicago Mob from NYC to L.A.

1971 film about the adventures of a car-delivery guy who makes a bet that he can get a '70 Dodge Challenger from Colorado to 'Frisco, Cali in less than 15 hours.

1971 film that to this day serves as a literally moving panoramic of US Route 66 in the pre-Interstate era.

Mel Gibson as a sheriff in an apocalyptic Australia depleted of oil.

C. Thomas Howell and Jennifer Jason Leigh as two travelers in the Mojave Desert trying to lose a psychotic stalker played by Rutger Hauer in this 1986 film.

Desi Arnaz, Jr., Robert Carradine and Melanie Griffith starred in this 1977 film about three cats stranded in Alaska after their car is broken into and robbed.

Quentin Tarantino wrote and directed this 2007 slasher film about a psychotic stunt man who stalks women before murdering them in staged car crashes.

2008 film about a man and woman who meet in Baja, California en route to being spiritually reborn after she crawls out (dead) from a car crash.

2004 biopic about the Argentine Marxist Revolutionary Che Guevara's two-wheeled trek across South America.

Oscars all over the place for this 1988 film in which the open road was integral for a narcissistic car salesman traveling it with his autistic brother (Dustin Hoffman).

Burt Reynolds. Farrah Fawcett. Roger Moore. Jackie Chan. Dom DeLuise. Dean Martin. Sammy Davis, Jr. Cross-country race.

Steve Martin and John Candy as an oddly-fated couple trying to get Martin's character back home to Chicago for Thanksgiving.

Justin Long and Gina Philips as a brother and sister trying to lose a(n) hideous, pesky demon who has their scent as they travel across the Florida countryside.

1967 film starring Warren Beatty and Faye Dunaway as the Depression-era crime duo.

A young Tatum O'Neal won an Oscar for her role traveling Depression-era dirt roads with her con artist (and real-life) dad in this 1973 film.

Robert Downey, Jr. as a guy stuck at the airport who just wants to see the birth of his child; Zach Galifianakis as an eccentric aspiring actor; a long road to Cali together.

John Travolta, Martin Lawrence, Tim Allen and William H. Macy as four gents who—in mid-life crisis mode—hit the open road on their Harleys.

A young man commits suicide and finds himself cruisin' the highway with a fellow dead Russian friend and a hitchhiker looking for 'the people in charge.'

Four friends embark on an 1,800 mile trek to retrieve an illicit tape mistakenly mailed to a girl friend in this 2000 film.

The misadventures of Bob Munro (Robin Williams) and his family as they roll down the open road en route to the Rocky Mountains.

Chick flick about three women—played by Whoopi Goldberg, Drew Barrymore and Mary Louise-Parker—on a cross-country road trip to California together.