| -Brain and Spinal cord -T-cell mediated -demyelination |
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| -Adrenal Cortex -associated with HLA alleles |
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| -RBC lysis - caused by mimicry, drug interaction |
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| -affects BM of lung alveoli and kidney glomeruli |
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| -Hypothyroidism -t-cell mediated |
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| -affects platelets -bleeding into skin and mucosal surfaces |
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| -affects Beta cells and islets of Langerhans -T-cell and delayed type hypersensitivity |
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| - affects nicotinic ach receptors -muscle weakness/droopy eyelid/difficult swallowing |
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| - affects gastric parietal cells -tcell mediated -malabsorption of B12 |
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| -seminferous tubules -infertility -antibody mediated |
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| -glomerulonephritis - fever -polyarthritis -immune complex mediated |
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| -pain and stiffness -inflam of vertebrae |
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| -autoantibodies against Fc region of IgG |
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| -chronic hardening and shrinking of CT |
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| -t-cell mediated -Fas mutation |
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