| HR | Player | Team |
| 296 | |
| 290 | |
| 235 | |
| 204 | |
| 202 | |
| 197 | |
| 181 | |
| 180 | |
| 179 | |
| 177 | |
| 172 | |
| 163 | |
| 159 | |
| 159 | |
| 155 | |
| 152 | |
| 152 | |
| 151 | |
| 148 | |
| 145 | |
| 144 | |
| 143 | |
| 143 | |
| 139 | |
| 136 | |
| 134 | |
| | HR | Player | Team |
| 129 | |
| 127 | |
| 122 | |
| 121 | |
| 121 | |
| 120 | |
| 120 | |
| 118 | |
| 116 | |
| 115 | |
| 113 | |
| 113 | |
| 112 | |
| 112 | |
| 110 | |
| 110 | |
| 109 | |
| 109 | |
| 108 | |
| 108 | |
| 108 | |
| 107 | |
| 106 | |
| 103 | |
| 101 | |
| 82 (NYM), 77 (SFG), 76 (CHC) | |
| 99 (MIL) | |
| 95 (CAL) | |
| 95 (DET) | |
| 88 (NYY) | |
| 84 (CHW) | |
| 80 (STL) | |
| 79 (WSA/TEX) | |
| 79 (NYY) | |
| 78 (HOU) | |
| 75 (CIN) | |
| 74 (KC) | |
| 70 (CIN) | |
| 57 (MIL) | |
| 57 (MIN) | |
| 56 (ATL) | |
| 47 (STL) | |
| 47 (MIL) | |
| 47 (NYY) | |
| 47 (STL) | |
| 46 (ATL) | |
| 46 (SFG) | |
| 34 (MIL) | |
|