| Question | Answer | Difficulty |
| What is the name of the song that Penny and Sheldon sing when the other is sick? | |
| Who helps Penny when she dislocates her shoulder? | |
| Where do Raj, Howard, Leonard and Sheldon go to at the end of Season 2, and return from in the premiere of Season 3? | |
| What state is Penny originally from? | |
| What is the name of Raj's sister? | |
| What is the name of the contract Sheldon makes Leonard sign upon living with him? | |
| What word does Sheldon say after a joke or a prank? | |
| What is Amy's full name? | |
| Which of Howard's friends have fantasies about Bernadette and writes love poems about her? | |
| What is the name that Leonard and Penny give to the evaluation of their relationship in Season 5? | |
| Where is Raj from in India? | |
| How does Raj communicate with his parents? | |
| What is the name of the Comic Book Store owner? | |
| What country does Leonard plan to take Penny to for Valentine's Day but doesn't as she becomes ill? | |
| Who was Sheldon's mortal enemy after he failed to show at a conference Sheldon attended as a child? | |
| | Question | Answer | Difficulty |
| What is Sheldon's full job title? | |
| What is Leonard's full job title? | |
| What is Howard's full job title? | |
| What is Raj's full job title? | |
| Who had the first line in the Pilot episode? | |
| What did Howard do to provoke him to apologise to Bernadette via a song in the Cheesecake Factory? | |
| What do Raj, Leonard and Sheldon have that Howard doesn't? (He is mocked about it frequently) | |
| Who used and signed the napkin that Penny gives to Sheldon as a Christmas present? | |
| What does Amy get Sheldon to do when he 'helps' in her neurobiology lab? | |
| What item does Sheldon buy Amy to help them get back on track in their relationship? | |
| What did Howard try to do when Penny punches him? | |
| How did Amy and Sheldon meet (thanks to Howard and Raj)? | |
| In 'The Electric Can Opener Fluctuation', what does Howard wear to blend in with the Texans? | |
| What substance does Barry Kripke make Sheldon inhale to mess up his radio interview? | |
| Finish the quote as to why Sheldon has to sit in his spot: 'In the winter, that seat is close enough to the radiator to remain warm and yet not so close as to cause...' | |
| | Question | Answer | Difficulty |
| Spell Raj's surname | |
| What is the name of Leonard's North Korean girlfriend who is deported prior to the show starting? | |
| Which Sci-Fi series does Sheldon hate that Leonard loves? | |
| What is the brand of scooter that Howard has? | |
| Where does Penny's performance in the play 'Anne Frank' take place? | |
| What does Penny's boyfriend Zack think might happen to the moon when the guys fire a laser at it? | |
| In Sheldon's and Amy's game 'Counterfactuals', who wins World War Two if rhinos are domesticated pets? | |
| What is the name of the green drink that Penny makes Raj when he first talks to her? | |
| What specific gift does Bernadette get for Howard, which he interprets as 'rubbing it in' that she earns more money than him? | |
| What is the name of Kripke's robot that fights and destroys M.O.N.T.E.? | |
| What is the nickname of the middle-aged bald man in the Comic Book Store who is known for the clothes he wears? | |
| What theory does Penny try to explain to one of her many boyfriends after hearing it from Sheldon? | |
| What was the name of the cross-dresser who lived in Penny's flat before she did? | |
| What one word does Penny say to mess up the second date between her and the Comic Book Store owner? | |
| What is the number of the building that Leonard, Sheldon and Penny live in? | |
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