| Question | Answer | Hint |
| What were disease, starvation and lack of adequate supplies? | |
| Which 3 empires dominated trade in West African from 300 -1600 | |
| What did Portugal trade to West Africa? | |
| What did West Africa trade to Portugal? | |
| What river did the Spanish explore? | |
| Which body of water allowed the French and Spanish access to the interior portions of North America? | |
| Which body of water forms a border between the United States and Mexico? | |
| For which country did Champlain explore? | |
| Which American Indian tribe might Coronado have encountered? | |
| Which American Indian tribe might LaSalle have encountered? | |