Can you name the Autacoids?

created by mackb33
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ClassDrug (Generic)Mechanist/Uses
H1R antagonist; 5HT, a1 & MR blockmild sedative, anti-emetic
Serotonin Antagonists5HT2a selective antagonist, similar to Ketanserin but NO alpha activity
Serotonin AntagonistsBlocks 5HT7 & Dopamine receptors, atypical antipsychotic used in schizo. pts
H1R antagonist; 5HT, a1 & MR blockallergies and hypersensitivities, mild anti-cholinergic, mild sedative in OTC prep
Serotonin AgonistsAnxyolytic, 5HT1A agonist
Serotonin Agonists5HT 1B & 1D; migraines; constrict & prevent vasodilation and stretching of pain nerve endings, Inhibit endogenous NT (CGRP) release in perivascular space
H1R antagonist; 5HT, a1 & MR blockmild anti-cholinergic, moderate sedative, GI side effects
Serotonin Antagonists5HT3 blocker, Prevents Nausea and Vomiting after surgery/chemotherapy MAJOR
H1R antagonist; 5HT, a1 & MR blockallergies and hypersensitivities, mild anti-cholinergic, mild sedative in OTC prep
ClassDrug (Generic)Mechanist/Uses
H1R antagonist; 5HT, a1 & MR blockStrong Sedation, strong antichilinergic, ant-emetic
H1R antagonist; 5HT, a1 & MR blockstrong sedative, anxyolytic
Serotonin AgonistsGERD (withdrawn), 5HT4
H1R antagonist; 5HT, a1 & MR blockmoderate sedative, mild anti-cholinergic, 5HT2a antagonist, carcinoid syndrome, cold induced urticaria, 5HT syndrome
2nd generation Anti-Histamine0
2nd generation Anti-Histamine0
Serotonin Antagonists5HT2a blocker, also blocks alpha adrenergic receptors, blocks USM contraction, platelet aggregation, used in Europe for hypertension, not USA
2nd generation Anti-Histamine0
H1R antagonist; 5HT, a1 & MR blockStrong sedative, strong anticholinergic, anti-emetic
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Autacoids Quiz

  1. by mackb33
  • Created Sep 1, 2011 in Science
  • Game Plays 6

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