Anti-glycemic Agents

Random Miscellaneous Quiz

Can you name the Anti-glycemic Agents?

Quiz not verified by Sporcle

How to Play
Detemir - Levemir class
NPH Iletin III (Lilly) class
Humulin Br class
MOA: Increases hepatic insulin sensitivity. Works through AMP dependent kinase, a mastor allosteric regulator of metabolism, that senses lack of energy substrates in cells.
Humalog 50/50 class
Rosiglitazone (Avandia) class
Novolin 70/30 PenFill
Peak: None
Pioglitazone and glimepiride combo
Humulin N class
Regular Ileting II (Lilly) class
SE: GI effects, occasional low B12, rare lactic acidosis, ovulation in PCO
Metformin and glipizide combo
Humulin 70/30
Use: Human insulin is made by recombinant technology
Onset 30 minutes - 1 hour
MOA: Lowers threshold for insulin release. Effective early; secondary failure common.
Rosiglitazone and glimepiride combo
Duration ~14 hours
MOA: Decreases hepatic glucose production, decreases peripheral insulin resistance, increases glucose uptake, decrease gluconeogenesis, decreases fatty liver,
MOA: Effective in long-duration DM, weight loss, no hypoglycemia, lowers insuling, TG, LDL
Nolvin N PenFill
P-kinetics: Eliminated by renal filtration
Use: Controls blood sugar between meals and during sleep
Use: Controls blood sugar surges at mealtime
Lispro - Humalog (Lilly) class
Repalinide class
Humulin Ultralente class
Contraindications: Intestinal dz, cirrhosis, renal dz (creatinine > 2)
Nololin 70/30
Sitagliptin (Januvia) class
Novolin R (Novo Nordisk) class
Novolin 70/30 class
SE: Similar to sulfonureas but with less risk of prolonged hypoglycemia.
Humalog class
Avapro - Novalog (Novo Nordisk) class
Novolin R PenFill
Onset 1-4 hours
SE: GI effects, increased transaminases (monitor). No hypoglycemia
Apidra class
Humulin R (Lilly) class
MOA: Decreases insulin resistance, increase muscle and adipose tissue glucose uptake, decreased hepatic glucose output.
Glyburide (Micronase, Diabeta) class
Glipizide (Glucotrol; Glucotrol XL) class
Rosiglitazone and metformin combo
P-kinetics: Rapid absorption, short duration.
MOA: Lowers postprandial glucose rise by delaying CHO absorption. Decreases glucose absorption secondary to decreased digestion of carbohydrates.
Humulin 50/50
Humulin N (NPH) (Lilly) class
Glusine - Apidra (Avemtis) class
Novolog class
Novolog Mix 70/30 class
Novolin R class
Metformin class
Peak 6-8 hours
Metformin and glyburide combo
Humalog 75/25 Mix class
Use: DM II. Most effective in lean patients.
Sitagliptin and metformin combo
Peak: 1 hour
SE: No hypoglycemia
Duration 18-24 hours (12-16 hours)
Novolin N class
Duration: 18-20 hours
Nolovin R PenFill
Peak 2 - 5 hours
SE: Hypoglycemia, weight gain, GI effects.
Duration 3 - 4 hours (4-5 hours)
Acarbose class
Miglitol class
Glargine - Lantus class
Use: Combines rapid-acting and intermediate-acting insulin. Controls blood sugar at mealtime and all day and night
SE: Increased plasma volume, edema, CHF, ovulation in PCO, mild anemia, rare liver toxicity, risk of fx in women. No hypoglycemia
Use: Onset and duration are rough within the range listed from person to person
MOA: Inhibit enzymatic degradation of incretin hormones. Unlike most PO meds for DM, does not promote wt gain, there may even be slight wt loss.
Exenatide class
Humalog Mix 75/25 class
Humulin L (Lente) (Lilly) class
MOA: Bind to SU receptor on surface of beta cells, closing K+ATP channels -> to depolarization of cell membrane, allowing Ca++ to enter cell -> in insulin secretion.
Pioglitazone (Actos) class
SE: Nausea, other GI effects, rare reports of pancreatitis
Duration: 20-24 hours
Metformin and pioglitazone combo
Contraindications: Class III/IV CHF
Novolog Mix 70/30 class
MOA: Similar to sulfonureas.
Novolog Mix 70/30 PenFill class
Contraindications: Renal dz, liver dz, CHF, dehydration, shock, acidosis, alcoholism
Onset 15-30 minutes
Humalog Mix 50/50 class
P-kinetics: 100 mg once daily
P-kinetics: Injected SQ BID
Onset: 1-2 hours
MOA: GLP-1 agonist. Has all the properties of human GLP-1. 10 lb or greater wt loss in 1 yr
Nololin N (NPH) (Lilly) class
Duration 5-7 hours (6 - 8 hours)
MOA: Binds to PPAR-gamma, a nuclear receptor regulating differentiation of cells (adipocytes, vascular tissue). Decreased plasma fatty acid levels, decreased central adiposity, res
Use: First-line for most DM II, esp. obese.
Glimepiride (Amaryl) class

Friend Scores

  Player Best Score Plays Last Played
You You haven't played this game yet.

You Might Also Like...


Created Jan 16, 2012ReportNominate