| Counties it Passes Through | US Highway Number | Miles in Pennsylvania |
| Crawford, Erie, Warren, McKean, Potter, Tioga, Bradford, Wyoming, Lackawanna, Wayne, and Pike Counties | |
| Erie County | |
| Beaver, Allegheny, Westmoreland, Somerset, Bedford, Fulton, Franklin, Adams, York, Lancaster, Chester, Delaware, Montgomery, and Philadelphia Counties | |
| Crawford, Mercer, Venango, Clarion, Jefferson, Clearfield, Centre, Mifflin, Juniata, Perry, Dauphin, Lebanon, Lancaster, Chester, and Delaware Counties | |
| Dauphin, Schuylkill, Carbon, and Monroe Counties | |
| Bedford, Blair, Centre, Clinton, Lycoming, Sullivan, and Bradford Counties | |
| Washington, Allegheny, Westmoreland, Indiana, Cambria, Blair, Huntingdon, Mifflin, Juniata, Perry, Dauphin, Lebanon, Berks, Lehigh, and Northampton Counties | |
| Washington, Fayette, and Somerset Counties | |
| Lancaster, Berks, and Lehigh Counties | |
| Adams, York, Cumberland, Perry, Juniata, Snyder, Union, Lycoming, and Tioga Counties | |
| Franklin, Cumberland, Perry, Juniata, Snyder, Union, Montour, Columbia, Luzerne, Lackawanna, Wyoming, and Susquehanna Counties | |
| Delaware, Chester, Montgomery, and Bucks Counties | |
| | Counties it Passes Through | US Highway Number | Miles in Pennsylvania |
| Lawrence County | |
| Fulton, Huntingdon, Mifflin, and Snyder Counties | |
| Chester, Delaware, Philadelphia, and Bucks Counties | |
| Somerset, Cambria, Clearfield, Jefferson, Elk, and McKean Counties | |
| Delaware, Philadelphia, and Bucks Counties | |
| Erie County | |
| Fayette, Westmoreland, Indiana, Jefferson, and Clearfield Counties | |
| Dauphin, Lebanon, Berks, Montgomery, and Chester Counties | |
| Pike County | |
| Greene, Washington, Allegheny, Butler, Lawrence, Mercer, Crawford, and Erie Counties | |
| Mercer, Venango, Forest, and Warren Counties | |
|