Physiology part A

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Type of pH disturbance: Hyperventilation due to anxiety
2 physiological adaptations to altitude
Signals from peripheral chemoreceptors are relayed toabbreviation
Type of pH disturbance: Acetozolamide
Infusion of 1l normal saline over 20 mins causes CO to
Hypothalamus function: Ventromedial nucleus
ECG after 130% K+ would show
Which part of the adrenals secretes cortisol?
Eccrine glandular secretion is increased by topical
ADH is released into the blood from the
pH 7.3
Type of pH disturbance: Hyperaldosteronism
Plasma K+ conc is sensed by the
Osmolarity of blood supplying the hypothalamus affects the release of
Cushing's syndrome heightens, cause:
Daily sweat loss (ml)
Left sided heart failure is commonly associated with
Hormone regulation plasma iron
pH 7.5
Type of pH disturbance: Renal failure
PlasmaK+ rises causes the secretion of which hormone
HPA stimulation causes decreased proliferation of ___ but increased numbers of
Hypothalamus function: Lateral hypothalamus
Type of pH disturbance: Vomiting
Do beta adrenoreceptor antagonists affect transmission at the ganglion?
Anaesthetic decreasing intracellular calcium accumulation in cardiac myocytes
Main problem at altitude is lowabbreviation
Treat hyperkalaemia with 2 things
Ascending 4000m over 24 hours would lead to a PaCO2 of (mmHg)
Stimulating HPA increases blood ____ conc, this is mediated by _____
Hypothalamus function: Supraoptic/paraventricular nucleus
HPA stands for
Septic shock is characterised by a fall in
Calcitonin is synthesised in the
Long term effects of aldosterone
Above core temp, above thermoneutral zone
Conn's syndrome
Exposing skin to moving air increases
Iron efflux from macrophages and enterocytes is via
Hypothalamus function: Hormone acting on the arcuate nucleus
Type of pH disturbance: Insulin deficiency
Inflammatory cytokines decrease the
Submersion in water increases skin
Anaesthetics ____ ventilatory drive
Sudden increase in SVR causes CO to
Where in the hypothalamus is ADH synthesised?
Peripheral chemoreceptors sense (x3)abbreviations
Protein binding intracellular iron
Precursor of NO
Main stimulus for NO production
Daily water production from metabolism of carbs & lipid (ml)
Supine to standing causes CO to
Anaesthetics ____ SVR
pH 7.35
25-hydroxycholecalciferol is synthesised in the
Hypothalamus function: Anterior nucleus
Time of day with highest temperaturetime range (with units)
Duodenal iron transporter
ACTH stimulates release of which 2 hormones?
3 Calcitonin targets,
Amiloride directly blocks
Rate of heat loss is related to body mass to the power:fraction
Widespread poor perfusion of tissues leads to
Addison's syndrome is a reduction in
Prostacyclins cause vsm to ___ via activation of?
Type of pH disturbance: COPD
Enzyme that NO activates on binding to SM receptor
Short duration local anaesthetics reduce postoperative
Diuretic with anti-androgen effects
Local metabolites from active muscle cause primary
Mineralocorticooid receptor antagonist
A few days at altitude causes pulmonary ____
Anaesthetics ____ myocardial contractility
Short term effects of aldosterone
Mean pressure in the vascular system if the circulation stops is defined as
Below core temp, outside thermoneutral zone (2 responses)
pH 7.45
Above core temp, within thermoneutral zone
Which part of the adrenals secretes aldosterone?
Temperature in women rises by how much on which day of the cycle?range, day
2 causes of hypokalaemia
2 PTH targets,
Protein binding iron in plasma
Hormone that affects renal hydroxylation of vitamin D3
Type of pH disturbance: Narcotic drugs
3 stimuli that when increased increase local blood flow:full names
Endothelin 1 is raised in
Below core temp, within thermoneutral zone
Infusion of a B1 antagonist causes CO to
Nerve that carries afferent signals from the carotid sinus barorecptors
Time of day with lowest temperaturetime range (with units)
Anaesthetics ____ Upper airway resistance
1,25-dihydroxycholecalciferol is synthesised in
Type of pH disturbance: Exercise
pH 6.9
Local inflammation leads to increased
Minimum daily urine production (litres)
Normal K+ intake/output (mEq)
Anaesthetics ____ VQ mismatch
Central chemoreceptors sense (x2)

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