Physiology part A

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Ascending 4000m over 24 hours would lead to a PaCO2 of (mmHg)
Normal K+ intake/output (mEq)
pH 7.3
Type of pH disturbance: Hyperventilation due to anxiety
Type of pH disturbance: Hyperaldosteronism
ADH is released into the blood from the
2 PTH targets,
Anaesthetics ____ SVR
Hypothalamus function: Anterior nucleus
Type of pH disturbance: Vomiting
Local inflammation leads to increased
Protein binding iron in plasma
Minimum daily urine production (litres)
Addison's syndrome is a reduction in
Nerve that carries afferent signals from the carotid sinus barorecptors
Anaesthetics ____ VQ mismatch
Type of pH disturbance: Narcotic drugs
Duodenal iron transporter
Daily sweat loss (ml)
Below core temp, outside thermoneutral zone (2 responses)
2 causes of hypokalaemia
Which part of the adrenals secretes aldosterone?
Hypothalamus function: Ventromedial nucleus
Type of pH disturbance: Renal failure
Sudden increase in SVR causes CO to
Central chemoreceptors sense (x2)
Short duration local anaesthetics reduce postoperative
Widespread poor perfusion of tissues leads to
Which part of the adrenals secretes cortisol?
Hypothalamus function: Lateral hypothalamus
Cushing's syndrome heightens, cause:
Rate of heat loss is related to body mass to the power:fraction
Time of day with lowest temperaturetime range (with units)
Mean pressure in the vascular system if the circulation stops is defined as
Peripheral chemoreceptors sense (x3)abbreviations
pH 6.9
Left sided heart failure is commonly associated with
Main problem at altitude is lowabbreviation
Endothelin 1 is raised in
Exposing skin to moving air increases
Amiloride directly blocks
Hypothalamus function: Hormone acting on the arcuate nucleus
Anaesthetic decreasing intracellular calcium accumulation in cardiac myocytes
Hypothalamus function: Supraoptic/paraventricular nucleus
Time of day with highest temperaturetime range (with units)
Infusion of a B1 antagonist causes CO to
ACTH stimulates release of which 2 hormones?
Anaesthetics ____ myocardial contractility
1,25-dihydroxycholecalciferol is synthesised in
Enzyme that NO activates on binding to SM receptor
3 Calcitonin targets,
Eccrine glandular secretion is increased by topical
Temperature in women rises by how much on which day of the cycle?range, day
pH 7.5
Supine to standing causes CO to
Osmolarity of blood supplying the hypothalamus affects the release of
Infusion of 1l normal saline over 20 mins causes CO to
Diuretic with anti-androgen effects
Submersion in water increases skin
Stimulating HPA increases blood ____ conc, this is mediated by _____
Hormone that affects renal hydroxylation of vitamin D3
Type of pH disturbance: COPD
Iron efflux from macrophages and enterocytes is via
Main stimulus for NO production
PlasmaK+ rises causes the secretion of which hormone
Calcitonin is synthesised in the
2 physiological adaptations to altitude
pH 7.45
HPA stands for
Anaesthetics ____ ventilatory drive
Type of pH disturbance: Acetozolamide
Above core temp, above thermoneutral zone
Septic shock is characterised by a fall in
Type of pH disturbance: Insulin deficiency
Type of pH disturbance: Exercise
Anaesthetics ____ Upper airway resistance
Inflammatory cytokines decrease the
A few days at altitude causes pulmonary ____
ECG after 130% K+ would show
Precursor of NO
Mineralocorticooid receptor antagonist
Where in the hypothalamus is ADH synthesised?
3 stimuli that when increased increase local blood flow:full names
Do beta adrenoreceptor antagonists affect transmission at the ganglion?
Above core temp, within thermoneutral zone
Treat hyperkalaemia with 2 things
25-hydroxycholecalciferol is synthesised in the
pH 7.35
Local metabolites from active muscle cause primary
Short term effects of aldosterone
Below core temp, within thermoneutral zone
Conn's syndrome
Protein binding intracellular iron
Signals from peripheral chemoreceptors are relayed toabbreviation
Plasma K+ conc is sensed by the
Hormone regulation plasma iron
Long term effects of aldosterone
Prostacyclins cause vsm to ___ via activation of?
Daily water production from metabolism of carbs & lipid (ml)
HPA stimulation causes decreased proliferation of ___ but increased numbers of

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