Physiology part A

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Anaesthetics ____ Upper airway resistance
Above core temp, above thermoneutral zone
pH 6.9
Rate of heat loss is related to body mass to the power:fraction
Type of pH disturbance: Hyperventilation due to anxiety
Anaesthetics ____ myocardial contractility
Iron efflux from macrophages and enterocytes is via
Treat hyperkalaemia with 2 things
Infusion of 1l normal saline over 20 mins causes CO to
ADH is released into the blood from the
3 Calcitonin targets,
Mean pressure in the vascular system if the circulation stops is defined as
Amiloride directly blocks
PlasmaK+ rises causes the secretion of which hormone
Eccrine glandular secretion is increased by topical
Type of pH disturbance: Renal failure
2 PTH targets,
Anaesthetics ____ ventilatory drive
Time of day with lowest temperaturetime range (with units)
Main problem at altitude is lowabbreviation
pH 7.3
Local metabolites from active muscle cause primary
Hypothalamus function: Lateral hypothalamus
Normal K+ intake/output (mEq)
Which part of the adrenals secretes cortisol?
Do beta adrenoreceptor antagonists affect transmission at the ganglion?
Daily sweat loss (ml)
Anaesthetics ____ VQ mismatch
Peripheral chemoreceptors sense (x3)abbreviations
Hypothalamus function: Ventromedial nucleus
Left sided heart failure is commonly associated with
Minimum daily urine production (litres)
Mineralocorticooid receptor antagonist
Plasma K+ conc is sensed by the
Type of pH disturbance: Vomiting
Conn's syndrome
Supine to standing causes CO to
Osmolarity of blood supplying the hypothalamus affects the release of
Type of pH disturbance: Hyperaldosteronism
Endothelin 1 is raised in
Short term effects of aldosterone
Anaesthetics ____ SVR
ECG after 130% K+ would show
Sudden increase in SVR causes CO to
Below core temp, outside thermoneutral zone (2 responses)
Local inflammation leads to increased
Precursor of NO
Cushing's syndrome heightens, cause:
Long term effects of aldosterone
Protein binding intracellular iron
Hypothalamus function: Anterior nucleus
Daily water production from metabolism of carbs & lipid (ml)
HPA stimulation causes decreased proliferation of ___ but increased numbers of
pH 7.45
Duodenal iron transporter
Calcitonin is synthesised in the
Hypothalamus function: Supraoptic/paraventricular nucleus
Where in the hypothalamus is ADH synthesised?
Infusion of a B1 antagonist causes CO to
Prostacyclins cause vsm to ___ via activation of?
A few days at altitude causes pulmonary ____
Septic shock is characterised by a fall in
ACTH stimulates release of which 2 hormones?
Short duration local anaesthetics reduce postoperative
Hormone regulation plasma iron
Widespread poor perfusion of tissues leads to
Type of pH disturbance: Exercise
Type of pH disturbance: Narcotic drugs
Anaesthetic decreasing intracellular calcium accumulation in cardiac myocytes
Above core temp, within thermoneutral zone
Type of pH disturbance: COPD
Which part of the adrenals secretes aldosterone?
Submersion in water increases skin
2 physiological adaptations to altitude
Temperature in women rises by how much on which day of the cycle?range, day
3 stimuli that when increased increase local blood flow:full names
Type of pH disturbance: Insulin deficiency
Central chemoreceptors sense (x2)
HPA stands for
25-hydroxycholecalciferol is synthesised in the
Below core temp, within thermoneutral zone
Type of pH disturbance: Acetozolamide
Protein binding iron in plasma
1,25-dihydroxycholecalciferol is synthesised in
Time of day with highest temperaturetime range (with units)
Signals from peripheral chemoreceptors are relayed toabbreviation
Exposing skin to moving air increases
Stimulating HPA increases blood ____ conc, this is mediated by _____
Enzyme that NO activates on binding to SM receptor
Nerve that carries afferent signals from the carotid sinus barorecptors
Addison's syndrome is a reduction in
Main stimulus for NO production
Ascending 4000m over 24 hours would lead to a PaCO2 of (mmHg)
pH 7.5
Inflammatory cytokines decrease the
2 causes of hypokalaemia
Hormone that affects renal hydroxylation of vitamin D3
Hypothalamus function: Hormone acting on the arcuate nucleus
pH 7.35
Diuretic with anti-androgen effects

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