Physiology part A

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Endothelin 1 is raised in
pH 7.5
Hypothalamus function: Anterior nucleus
Short term effects of aldosterone
Below core temp, within thermoneutral zone
Hypothalamus function: Supraoptic/paraventricular nucleus
Enzyme that NO activates on binding to SM receptor
Addison's syndrome is a reduction in
Long term effects of aldosterone
Type of pH disturbance: Acetozolamide
Do beta adrenoreceptor antagonists affect transmission at the ganglion?
Normal K+ intake/output (mEq)
Inflammatory cytokines decrease the
Anaesthetics ____ myocardial contractility
Below core temp, outside thermoneutral zone (2 responses)
Temperature in women rises by how much on which day of the cycle?range, day
Type of pH disturbance: Narcotic drugs
Hormone that affects renal hydroxylation of vitamin D3
Mean pressure in the vascular system if the circulation stops is defined as
Duodenal iron transporter
2 causes of hypokalaemia
pH 7.35
3 stimuli that when increased increase local blood flow:full names
1,25-dihydroxycholecalciferol is synthesised in
Diuretic with anti-androgen effects
ACTH stimulates release of which 2 hormones?
Local inflammation leads to increased
Protein binding intracellular iron
Hypothalamus function: Ventromedial nucleus
Rate of heat loss is related to body mass to the power:fraction
Eccrine glandular secretion is increased by topical
pH 7.45
2 PTH targets,
PlasmaK+ rises causes the secretion of which hormone
Type of pH disturbance: Hyperaldosteronism
Amiloride directly blocks
Ascending 4000m over 24 hours would lead to a PaCO2 of (mmHg)
Signals from peripheral chemoreceptors are relayed toabbreviation
Which part of the adrenals secretes aldosterone?
Which part of the adrenals secretes cortisol?
Time of day with highest temperaturetime range (with units)
pH 7.3
Type of pH disturbance: Insulin deficiency
Cushing's syndrome heightens, cause:
Main problem at altitude is lowabbreviation
Protein binding iron in plasma
A few days at altitude causes pulmonary ____
Widespread poor perfusion of tissues leads to
Hypothalamus function: Hormone acting on the arcuate nucleus
Daily sweat loss (ml)
2 physiological adaptations to altitude
Treat hyperkalaemia with 2 things
Plasma K+ conc is sensed by the
Conn's syndrome
Anaesthetic decreasing intracellular calcium accumulation in cardiac myocytes
Hypothalamus function: Lateral hypothalamus
Submersion in water increases skin
Minimum daily urine production (litres)
ADH is released into the blood from the
Anaesthetics ____ Upper airway resistance
Hormone regulation plasma iron
Short duration local anaesthetics reduce postoperative
Central chemoreceptors sense (x2)
Prostacyclins cause vsm to ___ via activation of?
Left sided heart failure is commonly associated with
Anaesthetics ____ SVR
3 Calcitonin targets,
Iron efflux from macrophages and enterocytes is via
Anaesthetics ____ ventilatory drive
Type of pH disturbance: COPD
pH 6.9
Infusion of a B1 antagonist causes CO to
Where in the hypothalamus is ADH synthesised?
Septic shock is characterised by a fall in
Local metabolites from active muscle cause primary
ECG after 130% K+ would show
Type of pH disturbance: Hyperventilation due to anxiety
Osmolarity of blood supplying the hypothalamus affects the release of
Time of day with lowest temperaturetime range (with units)
HPA stands for
Above core temp, within thermoneutral zone
HPA stimulation causes decreased proliferation of ___ but increased numbers of
Main stimulus for NO production
Peripheral chemoreceptors sense (x3)abbreviations
Type of pH disturbance: Exercise
Anaesthetics ____ VQ mismatch
Above core temp, above thermoneutral zone
Sudden increase in SVR causes CO to
Nerve that carries afferent signals from the carotid sinus barorecptors
Infusion of 1l normal saline over 20 mins causes CO to
Mineralocorticooid receptor antagonist
Supine to standing causes CO to
Exposing skin to moving air increases
Type of pH disturbance: Renal failure
25-hydroxycholecalciferol is synthesised in the
Type of pH disturbance: Vomiting
Calcitonin is synthesised in the
Daily water production from metabolism of carbs & lipid (ml)
Precursor of NO
Stimulating HPA increases blood ____ conc, this is mediated by _____

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