Physiology part A

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Below core temp, within thermoneutral zone
Infusion of 1l normal saline over 20 mins causes CO to
pH 7.35
3 stimuli that when increased increase local blood flow:full names
Diuretic with anti-androgen effects
ADH is released into the blood from the
Type of pH disturbance: Exercise
Peripheral chemoreceptors sense (x3)abbreviations
Anaesthetics ____ Upper airway resistance
Precursor of NO
2 causes of hypokalaemia
Type of pH disturbance: Narcotic drugs
Short duration local anaesthetics reduce postoperative
Amiloride directly blocks
ACTH stimulates release of which 2 hormones?
Exposing skin to moving air increases
Iron efflux from macrophages and enterocytes is via
pH 7.3
pH 7.5
Plasma K+ conc is sensed by the
Left sided heart failure is commonly associated with
pH 6.9
Treat hyperkalaemia with 2 things
Type of pH disturbance: Hyperaldosteronism
Prostacyclins cause vsm to ___ via activation of?
Anaesthetics ____ VQ mismatch
Sudden increase in SVR causes CO to
Calcitonin is synthesised in the
Daily water production from metabolism of carbs & lipid (ml)
Hypothalamus function: Supraoptic/paraventricular nucleus
A few days at altitude causes pulmonary ____
Mean pressure in the vascular system if the circulation stops is defined as
Type of pH disturbance: Renal failure
Type of pH disturbance: Acetozolamide
Type of pH disturbance: Insulin deficiency
Short term effects of aldosterone
Daily sweat loss (ml)
Anaesthetics ____ SVR
Addison's syndrome is a reduction in
Supine to standing causes CO to
Time of day with lowest temperaturetime range (with units)
HPA stands for
ECG after 130% K+ would show
Normal K+ intake/output (mEq)
Type of pH disturbance: Vomiting
2 PTH targets,
Duodenal iron transporter
Signals from peripheral chemoreceptors are relayed toabbreviation
Protein binding iron in plasma
Type of pH disturbance: Hyperventilation due to anxiety
Septic shock is characterised by a fall in
Do beta adrenoreceptor antagonists affect transmission at the ganglion?
Osmolarity of blood supplying the hypothalamus affects the release of
Rate of heat loss is related to body mass to the power:fraction
Where in the hypothalamus is ADH synthesised?
Main stimulus for NO production
Endothelin 1 is raised in
Hypothalamus function: Ventromedial nucleus
Main problem at altitude is lowabbreviation
Hormone regulation plasma iron
Above core temp, above thermoneutral zone
Inflammatory cytokines decrease the
Conn's syndrome
Type of pH disturbance: COPD
Submersion in water increases skin
Anaesthetics ____ myocardial contractility
Enzyme that NO activates on binding to SM receptor
Below core temp, outside thermoneutral zone (2 responses)
Hypothalamus function: Hormone acting on the arcuate nucleus
Ascending 4000m over 24 hours would lead to a PaCO2 of (mmHg)
Time of day with highest temperaturetime range (with units)
Central chemoreceptors sense (x2)
Anaesthetic decreasing intracellular calcium accumulation in cardiac myocytes
2 physiological adaptations to altitude
PlasmaK+ rises causes the secretion of which hormone
25-hydroxycholecalciferol is synthesised in the
Above core temp, within thermoneutral zone
Temperature in women rises by how much on which day of the cycle?range, day
Eccrine glandular secretion is increased by topical
Hormone that affects renal hydroxylation of vitamin D3
1,25-dihydroxycholecalciferol is synthesised in
Which part of the adrenals secretes cortisol?
Hypothalamus function: Anterior nucleus
Infusion of a B1 antagonist causes CO to
Stimulating HPA increases blood ____ conc, this is mediated by _____
Long term effects of aldosterone
Widespread poor perfusion of tissues leads to
Minimum daily urine production (litres)
Protein binding intracellular iron
Local metabolites from active muscle cause primary
HPA stimulation causes decreased proliferation of ___ but increased numbers of
pH 7.45
Mineralocorticooid receptor antagonist
Cushing's syndrome heightens, cause:
Which part of the adrenals secretes aldosterone?
Local inflammation leads to increased
Anaesthetics ____ ventilatory drive
Hypothalamus function: Lateral hypothalamus
3 Calcitonin targets,
Nerve that carries afferent signals from the carotid sinus barorecptors

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