Physiology part A

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Inflammatory cytokines decrease the
Hypothalamus function: Hormone acting on the arcuate nucleus
pH 6.9
Duodenal iron transporter
Local metabolites from active muscle cause primary
Ascending 4000m over 24 hours would lead to a PaCO2 of (mmHg)
Hormone regulation plasma iron
PlasmaK+ rises causes the secretion of which hormone
Anaesthetic decreasing intracellular calcium accumulation in cardiac myocytes
Exposing skin to moving air increases
Signals from peripheral chemoreceptors are relayed toabbreviation
Type of pH disturbance: Acetozolamide
Sudden increase in SVR causes CO to
A few days at altitude causes pulmonary ____
Calcitonin is synthesised in the
Plasma K+ conc is sensed by the
Amiloride directly blocks
Type of pH disturbance: Vomiting
Iron efflux from macrophages and enterocytes is via
pH 7.45
Type of pH disturbance: Hyperaldosteronism
Addison's syndrome is a reduction in
3 Calcitonin targets,
Time of day with lowest temperaturetime range (with units)
ACTH stimulates release of which 2 hormones?
Conn's syndrome
Diuretic with anti-androgen effects
Anaesthetics ____ Upper airway resistance
Above core temp, within thermoneutral zone
Mineralocorticooid receptor antagonist
Short duration local anaesthetics reduce postoperative
Precursor of NO
Main stimulus for NO production
Type of pH disturbance: COPD
Anaesthetics ____ ventilatory drive
Submersion in water increases skin
Eccrine glandular secretion is increased by topical
Type of pH disturbance: Exercise
Nerve that carries afferent signals from the carotid sinus barorecptors
Local inflammation leads to increased
HPA stimulation causes decreased proliferation of ___ but increased numbers of
Hypothalamus function: Ventromedial nucleus
Main problem at altitude is lowabbreviation
pH 7.3
Enzyme that NO activates on binding to SM receptor
Long term effects of aldosterone
Protein binding iron in plasma
Osmolarity of blood supplying the hypothalamus affects the release of
Hypothalamus function: Lateral hypothalamus
Mean pressure in the vascular system if the circulation stops is defined as
Minimum daily urine production (litres)
Left sided heart failure is commonly associated with
Anaesthetics ____ myocardial contractility
Daily sweat loss (ml)
Protein binding intracellular iron
ADH is released into the blood from the
Temperature in women rises by how much on which day of the cycle?range, day
1,25-dihydroxycholecalciferol is synthesised in
Which part of the adrenals secretes aldosterone?
2 physiological adaptations to altitude
Above core temp, above thermoneutral zone
Which part of the adrenals secretes cortisol?
Where in the hypothalamus is ADH synthesised?
Septic shock is characterised by a fall in
Supine to standing causes CO to
Normal K+ intake/output (mEq)
Infusion of a B1 antagonist causes CO to
2 PTH targets,
pH 7.5
Type of pH disturbance: Renal failure
Anaesthetics ____ SVR
Widespread poor perfusion of tissues leads to
3 stimuli that when increased increase local blood flow:full names
Time of day with highest temperaturetime range (with units)
Cushing's syndrome heightens, cause:
Treat hyperkalaemia with 2 things
HPA stands for
2 causes of hypokalaemia
Infusion of 1l normal saline over 20 mins causes CO to
pH 7.35
Rate of heat loss is related to body mass to the power:fraction
Type of pH disturbance: Insulin deficiency
Hypothalamus function: Supraoptic/paraventricular nucleus
Central chemoreceptors sense (x2)
Prostacyclins cause vsm to ___ via activation of?
Hypothalamus function: Anterior nucleus
Type of pH disturbance: Hyperventilation due to anxiety
ECG after 130% K+ would show
Daily water production from metabolism of carbs & lipid (ml)
25-hydroxycholecalciferol is synthesised in the
Endothelin 1 is raised in
Peripheral chemoreceptors sense (x3)abbreviations
Stimulating HPA increases blood ____ conc, this is mediated by _____
Hormone that affects renal hydroxylation of vitamin D3
Do beta adrenoreceptor antagonists affect transmission at the ganglion?
Short term effects of aldosterone
Below core temp, within thermoneutral zone
Below core temp, outside thermoneutral zone (2 responses)
Anaesthetics ____ VQ mismatch
Type of pH disturbance: Narcotic drugs

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