Physiology part A

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Widespread poor perfusion of tissues leads to
Nerve that carries afferent signals from the carotid sinus barorecptors
ACTH stimulates release of which 2 hormones?
Enzyme that NO activates on binding to SM receptor
2 PTH targets,
Precursor of NO
3 Calcitonin targets,
2 causes of hypokalaemia
Temperature in women rises by how much on which day of the cycle?range, day
Infusion of 1l normal saline over 20 mins causes CO to
Anaesthetics ____ ventilatory drive
PlasmaK+ rises causes the secretion of which hormone
Local inflammation leads to increased
Hormone regulation plasma iron
Endothelin 1 is raised in
Below core temp, outside thermoneutral zone (2 responses)
Normal K+ intake/output (mEq)
Prostacyclins cause vsm to ___ via activation of?
Type of pH disturbance: COPD
Hypothalamus function: Hormone acting on the arcuate nucleus
Minimum daily urine production (litres)
Main problem at altitude is lowabbreviation
Protein binding intracellular iron
Supine to standing causes CO to
HPA stimulation causes decreased proliferation of ___ but increased numbers of
Exposing skin to moving air increases
Rate of heat loss is related to body mass to the power:fraction
Sudden increase in SVR causes CO to
Above core temp, within thermoneutral zone
Type of pH disturbance: Narcotic drugs
Mean pressure in the vascular system if the circulation stops is defined as
Iron efflux from macrophages and enterocytes is via
Cushing's syndrome heightens, cause:
25-hydroxycholecalciferol is synthesised in the
Type of pH disturbance: Hyperventilation due to anxiety
Left sided heart failure is commonly associated with
pH 7.35
Duodenal iron transporter
pH 6.9
Hypothalamus function: Ventromedial nucleus
1,25-dihydroxycholecalciferol is synthesised in
Hypothalamus function: Supraoptic/paraventricular nucleus
Treat hyperkalaemia with 2 things
Main stimulus for NO production
Mineralocorticooid receptor antagonist
Time of day with highest temperaturetime range (with units)
Which part of the adrenals secretes cortisol?
Long term effects of aldosterone
Ascending 4000m over 24 hours would lead to a PaCO2 of (mmHg)
Addison's syndrome is a reduction in
Septic shock is characterised by a fall in
Central chemoreceptors sense (x2)
Hypothalamus function: Anterior nucleus
Anaesthetics ____ SVR
Stimulating HPA increases blood ____ conc, this is mediated by _____
Which part of the adrenals secretes aldosterone?
Eccrine glandular secretion is increased by topical
Where in the hypothalamus is ADH synthesised?
Hypothalamus function: Lateral hypothalamus
Plasma K+ conc is sensed by the
Type of pH disturbance: Acetozolamide
Daily sweat loss (ml)
Type of pH disturbance: Vomiting
Osmolarity of blood supplying the hypothalamus affects the release of
Short duration local anaesthetics reduce postoperative
Hormone that affects renal hydroxylation of vitamin D3
Conn's syndrome
Protein binding iron in plasma
pH 7.3
ECG after 130% K+ would show
pH 7.45
Signals from peripheral chemoreceptors are relayed toabbreviation
Local metabolites from active muscle cause primary
Time of day with lowest temperaturetime range (with units)
Above core temp, above thermoneutral zone
A few days at altitude causes pulmonary ____
Anaesthetic decreasing intracellular calcium accumulation in cardiac myocytes
Do beta adrenoreceptor antagonists affect transmission at the ganglion?
Anaesthetics ____ myocardial contractility
Below core temp, within thermoneutral zone
Anaesthetics ____ VQ mismatch
Type of pH disturbance: Insulin deficiency
Inflammatory cytokines decrease the
HPA stands for
Type of pH disturbance: Hyperaldosteronism
Peripheral chemoreceptors sense (x3)abbreviations
2 physiological adaptations to altitude
pH 7.5
Daily water production from metabolism of carbs & lipid (ml)
Type of pH disturbance: Exercise
Type of pH disturbance: Renal failure
Calcitonin is synthesised in the
Infusion of a B1 antagonist causes CO to
Diuretic with anti-androgen effects
ADH is released into the blood from the
3 stimuli that when increased increase local blood flow:full names
Submersion in water increases skin
Anaesthetics ____ Upper airway resistance
Short term effects of aldosterone
Amiloride directly blocks

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