Science / Physiology part A

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Hypothalamus function: Anterior nucleus
Mean pressure in the vascular system if the circulation stops is defined as
Prostacyclins cause vsm to ___ via activation of?
Anaesthetics ____ ventilatory drive
Hypothalamus function: Ventromedial nucleus
Duodenal iron transporter
Below core temp, outside thermoneutral zone (2 responses)
Daily sweat loss (ml)
Sudden increase in SVR causes CO to
Iron efflux from macrophages and enterocytes is via
Addison's syndrome is a reduction in
Ascending 4000m over 24 hours would lead to a PaCO2 of (mmHg)
pH 7.45
Nerve that carries afferent signals from the carotid sinus barorecptors
pH 7.3
Type of pH disturbance: Insulin deficiency
2 physiological adaptations to altitude
Calcitonin is synthesised in the
Infusion of a B1 antagonist causes CO to
2 causes of hypokalaemia
Temperature in women rises by how much on which day of the cycle?range, day
2 PTH targets,
Type of pH disturbance: Exercise
Normal K+ intake/output (mEq)
PlasmaK+ rises causes the secretion of which hormone
Which part of the adrenals secretes cortisol?
Septic shock is characterised by a fall in
Anaesthetics ____ Upper airway resistance
Anaesthetics ____ myocardial contractility
Precursor of NO
Hypothalamus function: Supraoptic/paraventricular nucleus
Widespread poor perfusion of tissues leads to
Below core temp, within thermoneutral zone
Conn's syndrome
Hormone that affects renal hydroxylation of vitamin D3
Cushing's syndrome heightens, cause:
Which part of the adrenals secretes aldosterone?
Stimulating HPA increases blood ____ conc, this is mediated by _____
Anaesthetic decreasing intracellular calcium accumulation in cardiac myocytes
Type of pH disturbance: Acetozolamide
Diuretic with anti-androgen effects
Local metabolites from active muscle cause primary
3 stimuli that when increased increase local blood flow:full names
Main stimulus for NO production
Eccrine glandular secretion is increased by topical
Submersion in water increases skin
ADH is released into the blood from the
Long term effects of aldosterone
Enzyme that NO activates on binding to SM receptor
Daily water production from metabolism of carbs & lipid (ml)
Infusion of 1l normal saline over 20 mins causes CO to
Treat hyperkalaemia with 2 things
Type of pH disturbance: Narcotic drugs
3 Calcitonin targets,
Main problem at altitude is lowabbreviation
A few days at altitude causes pulmonary ____
Hypothalamus function: Hormone acting on the arcuate nucleus
Peripheral chemoreceptors sense (x3)abbreviations
Plasma K+ conc is sensed by the
Inflammatory cytokines decrease the
Type of pH disturbance: Renal failure
Above core temp, within thermoneutral zone
Type of pH disturbance: Hyperaldosteronism
Anaesthetics ____ SVR
Type of pH disturbance: Vomiting
Time of day with highest temperaturetime range (with units)
Where in the hypothalamus is ADH synthesised?
HPA stimulation causes decreased proliferation of ___ but increased numbers of
25-hydroxycholecalciferol is synthesised in the
1,25-dihydroxycholecalciferol is synthesised in
pH 6.9
Short duration local anaesthetics reduce postoperative
Osmolarity of blood supplying the hypothalamus affects the release of
Signals from peripheral chemoreceptors are relayed toabbreviation
Local inflammation leads to increased
Hypothalamus function: Lateral hypothalamus
Left sided heart failure is commonly associated with
Rate of heat loss is related to body mass to the power:fraction
Type of pH disturbance: COPD
Supine to standing causes CO to
Type of pH disturbance: Hyperventilation due to anxiety
Amiloride directly blocks
Hormone regulation plasma iron
ECG after 130% K+ would show
Protein binding iron in plasma
Time of day with lowest temperaturetime range (with units)
Exposing skin to moving air increases
ACTH stimulates release of which 2 hormones?
Endothelin 1 is raised in
Anaesthetics ____ VQ mismatch
Protein binding intracellular iron
pH 7.35
pH 7.5
Central chemoreceptors sense (x2)
Do beta adrenoreceptor antagonists affect transmission at the ganglion?
HPA stands for
Above core temp, above thermoneutral zone
Minimum daily urine production (litres)
Short term effects of aldosterone
Mineralocorticooid receptor antagonist

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