Physiology part A

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Hypothalamus function: Supraoptic/paraventricular nucleus
Anaesthetics ____ ventilatory drive
Anaesthetics ____ SVR
Above core temp, within thermoneutral zone
Calcitonin is synthesised in the
Hormone regulation plasma iron
Protein binding iron in plasma
Mean pressure in the vascular system if the circulation stops is defined as
Cushing's syndrome heightens, cause:
Local metabolites from active muscle cause primary
Eccrine glandular secretion is increased by topical
Osmolarity of blood supplying the hypothalamus affects the release of
Infusion of a B1 antagonist causes CO to
Which part of the adrenals secretes aldosterone?
Anaesthetics ____ myocardial contractility
Long term effects of aldosterone
Hypothalamus function: Ventromedial nucleus
Treat hyperkalaemia with 2 things
Hypothalamus function: Anterior nucleus
Type of pH disturbance: Narcotic drugs
Daily sweat loss (ml)
pH 6.9
HPA stands for
Normal K+ intake/output (mEq)
Type of pH disturbance: Acetozolamide
Temperature in women rises by how much on which day of the cycle?range, day
Peripheral chemoreceptors sense (x3)abbreviations
Mineralocorticooid receptor antagonist
Prostacyclins cause vsm to ___ via activation of?
ADH is released into the blood from the
Below core temp, outside thermoneutral zone (2 responses)
25-hydroxycholecalciferol is synthesised in the
Do beta adrenoreceptor antagonists affect transmission at the ganglion?
Type of pH disturbance: Vomiting
Hypothalamus function: Lateral hypothalamus
Rate of heat loss is related to body mass to the power:fraction
pH 7.45
pH 7.5
Signals from peripheral chemoreceptors are relayed toabbreviation
Diuretic with anti-androgen effects
2 physiological adaptations to altitude
Inflammatory cytokines decrease the
Main stimulus for NO production
2 causes of hypokalaemia
Local inflammation leads to increased
Type of pH disturbance: Exercise
Minimum daily urine production (litres)
Nerve that carries afferent signals from the carotid sinus barorecptors
A few days at altitude causes pulmonary ____
Time of day with lowest temperaturetime range (with units)
pH 7.3
Type of pH disturbance: COPD
Endothelin 1 is raised in
ECG after 130% K+ would show
Addison's syndrome is a reduction in
Enzyme that NO activates on binding to SM receptor
Precursor of NO
Submersion in water increases skin
Hormone that affects renal hydroxylation of vitamin D3
Type of pH disturbance: Renal failure
Below core temp, within thermoneutral zone
Supine to standing causes CO to
ACTH stimulates release of which 2 hormones?
Main problem at altitude is lowabbreviation
Daily water production from metabolism of carbs & lipid (ml)
Which part of the adrenals secretes cortisol?
Anaesthetics ____ Upper airway resistance
Protein binding intracellular iron
Stimulating HPA increases blood ____ conc, this is mediated by _____
Sudden increase in SVR causes CO to
Duodenal iron transporter
Time of day with highest temperaturetime range (with units)
HPA stimulation causes decreased proliferation of ___ but increased numbers of
Type of pH disturbance: Hyperventilation due to anxiety
Septic shock is characterised by a fall in
Amiloride directly blocks
Hypothalamus function: Hormone acting on the arcuate nucleus
1,25-dihydroxycholecalciferol is synthesised in
Where in the hypothalamus is ADH synthesised?
Widespread poor perfusion of tissues leads to
3 Calcitonin targets,
Anaesthetics ____ VQ mismatch
Short term effects of aldosterone
Exposing skin to moving air increases
Short duration local anaesthetics reduce postoperative
Plasma K+ conc is sensed by the
Above core temp, above thermoneutral zone
PlasmaK+ rises causes the secretion of which hormone
pH 7.35
3 stimuli that when increased increase local blood flow:full names
Type of pH disturbance: Hyperaldosteronism
Iron efflux from macrophages and enterocytes is via
Type of pH disturbance: Insulin deficiency
2 PTH targets,
Anaesthetic decreasing intracellular calcium accumulation in cardiac myocytes
Left sided heart failure is commonly associated with
Conn's syndrome
Ascending 4000m over 24 hours would lead to a PaCO2 of (mmHg)
Infusion of 1l normal saline over 20 mins causes CO to
Central chemoreceptors sense (x2)

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Created Apr 5, 2012ReportNominate