Physiology part A

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Infusion of a B1 antagonist causes CO to
A few days at altitude causes pulmonary ____
Addison's syndrome is a reduction in
Hypothalamus function: Lateral hypothalamus
2 causes of hypokalaemia
Minimum daily urine production (litres)
Mean pressure in the vascular system if the circulation stops is defined as
Mineralocorticooid receptor antagonist
Plasma K+ conc is sensed by the
PlasmaK+ rises causes the secretion of which hormone
Type of pH disturbance: Hyperaldosteronism
Osmolarity of blood supplying the hypothalamus affects the release of
Daily water production from metabolism of carbs & lipid (ml)
Stimulating HPA increases blood ____ conc, this is mediated by _____
25-hydroxycholecalciferol is synthesised in the
Main stimulus for NO production
Type of pH disturbance: Acetozolamide
HPA stimulation causes decreased proliferation of ___ but increased numbers of
Short term effects of aldosterone
pH 7.35
Septic shock is characterised by a fall in
Type of pH disturbance: Insulin deficiency
Duodenal iron transporter
Type of pH disturbance: Vomiting
Normal K+ intake/output (mEq)
Time of day with lowest temperaturetime range (with units)
Ascending 4000m over 24 hours would lead to a PaCO2 of (mmHg)
Prostacyclins cause vsm to ___ via activation of?
Local inflammation leads to increased
Rate of heat loss is related to body mass to the power:fraction
Type of pH disturbance: Exercise
Which part of the adrenals secretes aldosterone?
pH 7.5
Which part of the adrenals secretes cortisol?
Hypothalamus function: Hormone acting on the arcuate nucleus
pH 7.3
Type of pH disturbance: COPD
Temperature in women rises by how much on which day of the cycle?range, day
Time of day with highest temperaturetime range (with units)
Nerve that carries afferent signals from the carotid sinus barorecptors
Conn's syndrome
3 Calcitonin targets,
ECG after 130% K+ would show
ACTH stimulates release of which 2 hormones?
2 PTH targets,
Long term effects of aldosterone
Diuretic with anti-androgen effects
Inflammatory cytokines decrease the
Local metabolites from active muscle cause primary
2 physiological adaptations to altitude
Hormone regulation plasma iron
Iron efflux from macrophages and enterocytes is via
Below core temp, within thermoneutral zone
Calcitonin is synthesised in the
Exposing skin to moving air increases
Do beta adrenoreceptor antagonists affect transmission at the ganglion?
Anaesthetic decreasing intracellular calcium accumulation in cardiac myocytes
Peripheral chemoreceptors sense (x3)abbreviations
Eccrine glandular secretion is increased by topical
Anaesthetics ____ Upper airway resistance
Above core temp, within thermoneutral zone
Protein binding iron in plasma
Submersion in water increases skin
Anaesthetics ____ VQ mismatch
Endothelin 1 is raised in
ADH is released into the blood from the
Enzyme that NO activates on binding to SM receptor
Hypothalamus function: Supraoptic/paraventricular nucleus
Left sided heart failure is commonly associated with
Short duration local anaesthetics reduce postoperative
Hypothalamus function: Ventromedial nucleus
pH 7.45
1,25-dihydroxycholecalciferol is synthesised in
Anaesthetics ____ ventilatory drive
Type of pH disturbance: Narcotic drugs
Below core temp, outside thermoneutral zone (2 responses)
Precursor of NO
Anaesthetics ____ myocardial contractility
Hormone that affects renal hydroxylation of vitamin D3
Type of pH disturbance: Hyperventilation due to anxiety
Above core temp, above thermoneutral zone
Hypothalamus function: Anterior nucleus
3 stimuli that when increased increase local blood flow:full names
Treat hyperkalaemia with 2 things
Supine to standing causes CO to
Infusion of 1l normal saline over 20 mins causes CO to
Amiloride directly blocks
Widespread poor perfusion of tissues leads to
Type of pH disturbance: Renal failure
Sudden increase in SVR causes CO to
Anaesthetics ____ SVR
Signals from peripheral chemoreceptors are relayed toabbreviation
Cushing's syndrome heightens, cause:
Main problem at altitude is lowabbreviation
Daily sweat loss (ml)
pH 6.9
Central chemoreceptors sense (x2)
Protein binding intracellular iron
HPA stands for
Where in the hypothalamus is ADH synthesised?

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