Physiology part A

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Iron efflux from macrophages and enterocytes is via
pH 7.35
Enzyme that NO activates on binding to SM receptor
1,25-dihydroxycholecalciferol is synthesised in
Protein binding intracellular iron
Time of day with lowest temperaturetime range (with units)
Anaesthetics ____ ventilatory drive
Central chemoreceptors sense (x2)
Widespread poor perfusion of tissues leads to
pH 7.45
Hormone that affects renal hydroxylation of vitamin D3
Precursor of NO
Local inflammation leads to increased
Prostacyclins cause vsm to ___ via activation of?
Addison's syndrome is a reduction in
ADH is released into the blood from the
Short duration local anaesthetics reduce postoperative
Diuretic with anti-androgen effects
Type of pH disturbance: COPD
Type of pH disturbance: Exercise
ACTH stimulates release of which 2 hormones?
Eccrine glandular secretion is increased by topical
Minimum daily urine production (litres)
Cushing's syndrome heightens, cause:
Type of pH disturbance: Insulin deficiency
HPA stands for
Which part of the adrenals secretes cortisol?
2 physiological adaptations to altitude
Peripheral chemoreceptors sense (x3)abbreviations
Main problem at altitude is lowabbreviation
Stimulating HPA increases blood ____ conc, this is mediated by _____
Hypothalamus function: Hormone acting on the arcuate nucleus
HPA stimulation causes decreased proliferation of ___ but increased numbers of
Long term effects of aldosterone
Conn's syndrome
Local metabolites from active muscle cause primary
Calcitonin is synthesised in the
Exposing skin to moving air increases
3 stimuli that when increased increase local blood flow:full names
Which part of the adrenals secretes aldosterone?
Sudden increase in SVR causes CO to
Anaesthetics ____ SVR
Supine to standing causes CO to
Main stimulus for NO production
Type of pH disturbance: Renal failure
Rate of heat loss is related to body mass to the power:fraction
25-hydroxycholecalciferol is synthesised in the
Inflammatory cytokines decrease the
Septic shock is characterised by a fall in
Above core temp, within thermoneutral zone
Where in the hypothalamus is ADH synthesised?
Mineralocorticooid receptor antagonist
Anaesthetic decreasing intracellular calcium accumulation in cardiac myocytes
Duodenal iron transporter
Submersion in water increases skin
Infusion of a B1 antagonist causes CO to
Amiloride directly blocks
Temperature in women rises by how much on which day of the cycle?range, day
Daily sweat loss (ml)
Type of pH disturbance: Hyperventilation due to anxiety
Left sided heart failure is commonly associated with
2 causes of hypokalaemia
Time of day with highest temperaturetime range (with units)
PlasmaK+ rises causes the secretion of which hormone
Hypothalamus function: Ventromedial nucleus
pH 6.9
Infusion of 1l normal saline over 20 mins causes CO to
2 PTH targets,
ECG after 130% K+ would show
3 Calcitonin targets,
Type of pH disturbance: Acetozolamide
Nerve that carries afferent signals from the carotid sinus barorecptors
Type of pH disturbance: Hyperaldosteronism
Mean pressure in the vascular system if the circulation stops is defined as
Hypothalamus function: Anterior nucleus
Ascending 4000m over 24 hours would lead to a PaCO2 of (mmHg)
Hypothalamus function: Supraoptic/paraventricular nucleus
Anaesthetics ____ myocardial contractility
pH 7.3
Treat hyperkalaemia with 2 things
Below core temp, outside thermoneutral zone (2 responses)
Osmolarity of blood supplying the hypothalamus affects the release of
Plasma K+ conc is sensed by the
Type of pH disturbance: Vomiting
Daily water production from metabolism of carbs & lipid (ml)
Type of pH disturbance: Narcotic drugs
Hormone regulation plasma iron
pH 7.5
A few days at altitude causes pulmonary ____
Endothelin 1 is raised in
Normal K+ intake/output (mEq)
Anaesthetics ____ Upper airway resistance
Below core temp, within thermoneutral zone
Signals from peripheral chemoreceptors are relayed toabbreviation
Do beta adrenoreceptor antagonists affect transmission at the ganglion?
Hypothalamus function: Lateral hypothalamus
Protein binding iron in plasma
Short term effects of aldosterone
Above core temp, above thermoneutral zone
Anaesthetics ____ VQ mismatch

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