Tumor Supressor Genes (Goljan Table 8-4)

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Can you name the Tumor Supressor Genes (Goljan Table 8-4)?

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Syndrome of brain tumors, sarcomas, breast carcinoma, an leukemia
Li Fraumeni
Syndrome of Cerebellar hemang, retinal angioma, bilat RCC and PCC
Regulates nuclear transcription (not VHL)
Gene product Prevents nuclear transcription (degrades catenin, an activator of nuclear transcription)
Breast, ovary carcinomas
Lung colon, breast carcinomas
activated by p53 product to promote apoptosis
Cerebellar hemang, retinal angioma, bilat RCC and PCC
InfoAnswerdetails
Gene product inhibits going from G1-S (not TGF beta or p53)
Product activates BAX gene and subsequent apoptosis; also inhib G1-S
Wilms' tumor
Familial polyposis
Gene product regulates DNA repair
Pancreatic and colorectal carcinomas
Regulates nuclear transcription (not WT1)
Gene product inhibits going from G1-S (not Rb or p53)
OSTEOSARCOMA, breast carcinoma, retinoblastoma

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Created Nov 27, 2012ReportNominate
Tags:Nintendo, detail, gene, table