| Info | Answer | details |
| OSTEOSARCOMA, breast carcinoma, retinoblastoma | |
| Breast, ovary carcinomas | |
| Product activates BAX gene and subsequent apoptosis; also inhib G1-S | |
| activated by p53 product to promote apoptosis | |
| Lung colon, breast carcinomas | |
| Familial polyposis | |
| Gene product Prevents nuclear transcription (degrades catenin, an activator of nuclear transcription) | |
| Pancreatic and colorectal carcinomas | |
| Cerebellar hemang, retinal angioma, bilat RCC and PCC | |
| | Info | Answer | details |
| Syndrome of Cerebellar hemang, retinal angioma, bilat RCC and PCC | |
| Wilms' tumor | |
| Gene product regulates DNA repair | |
| Regulates nuclear transcription (not VHL) | |
| Li Fraumeni | |
| Syndrome of brain tumors, sarcomas, breast carcinoma, an leukemia | |
| Regulates nuclear transcription (not WT1) | |
| Gene product inhibits going from G1-S (not Rb or p53) | |
| Gene product inhibits going from G1-S (not TGF beta or p53) | |
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