Tumor Supressor Genes (Goljan Table 8-4)

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Can you name the Tumor Supressor Genes (Goljan Table 8-4)?

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Wilms' tumor
Familial polyposis
Regulates nuclear transcription (not VHL)
Lung colon, breast carcinomas
Syndrome of Cerebellar hemang, retinal angioma, bilat RCC and PCC
Breast, ovary carcinomas
Li Fraumeni
OSTEOSARCOMA, breast carcinoma, retinoblastoma
Syndrome of brain tumors, sarcomas, breast carcinoma, an leukemia
InfoAnswerdetails
Gene product inhibits going from G1-S (not Rb or p53)
Pancreatic and colorectal carcinomas
Gene product Prevents nuclear transcription (degrades catenin, an activator of nuclear transcription)
Gene product regulates DNA repair
activated by p53 product to promote apoptosis
Cerebellar hemang, retinal angioma, bilat RCC and PCC
Regulates nuclear transcription (not WT1)
Product activates BAX gene and subsequent apoptosis; also inhib G1-S
Gene product inhibits going from G1-S (not TGF beta or p53)

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Created Nov 27, 2012ReportNominate
Tags:Nintendo, detail, gene, table