Tumor Supressor Genes (Goljan Table 8-4)

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Can you name the Tumor Supressor Genes (Goljan Table 8-4)?

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Pancreatic and colorectal carcinomas
Regulates nuclear transcription (not VHL)
Lung colon, breast carcinomas
Gene product inhibits going from G1-S (not TGF beta or p53)
Cerebellar hemang, retinal angioma, bilat RCC and PCC
Li Fraumeni
activated by p53 product to promote apoptosis
OSTEOSARCOMA, breast carcinoma, retinoblastoma
Syndrome of Cerebellar hemang, retinal angioma, bilat RCC and PCC
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Familial polyposis
Regulates nuclear transcription (not WT1)
Breast, ovary carcinomas
Gene product inhibits going from G1-S (not Rb or p53)
Syndrome of brain tumors, sarcomas, breast carcinoma, an leukemia
Wilms' tumor
Gene product regulates DNA repair
Gene product Prevents nuclear transcription (degrades catenin, an activator of nuclear transcription)
Product activates BAX gene and subsequent apoptosis; also inhib G1-S

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Created Nov 27, 2012ReportNominate
Tags:Nintendo, detail, gene, table