Can you name the Tumor Supressor Genes (Goljan Table 8-4)?

created by kofi703
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OSTEOSARCOMA, breast carcinoma, retinoblastoma
Breast, ovary carcinomas
Product activates BAX gene and subsequent apoptosis; also inhib G1-S
activated by p53 product to promote apoptosis
Lung colon, breast carcinomas
Familial polyposis
Gene product Prevents nuclear transcription (degrades catenin, an activator of nuclear transcription)
Pancreatic and colorectal carcinomas
Cerebellar hemang, retinal angioma, bilat RCC and PCC
InfoAnswerdetails
Syndrome of Cerebellar hemang, retinal angioma, bilat RCC and PCC
Wilms' tumor
Gene product regulates DNA repair
Regulates nuclear transcription (not VHL)
Li Fraumeni
Syndrome of brain tumors, sarcomas, breast carcinoma, an leukemia
Regulates nuclear transcription (not WT1)
Gene product inhibits going from G1-S (not Rb or p53)
Gene product inhibits going from G1-S (not TGF beta or p53)
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Tumor Supressor Genes (Goljan Table 8-4) Quiz

  1. by kofi703
  • Created Nov 27, 2012 in Science
  • Game Plays 12

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