Tumor Supressor Genes (Goljan Table 8-4)

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Can you name the Tumor Supressor Genes (Goljan Table 8-4)?

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Gene product Prevents nuclear transcription (degrades catenin, an activator of nuclear transcription)
Gene product inhibits going from G1-S (not Rb or p53)
Lung colon, breast carcinomas
Syndrome of brain tumors, sarcomas, breast carcinoma, an leukemia
Pancreatic and colorectal carcinomas
activated by p53 product to promote apoptosis
Product activates BAX gene and subsequent apoptosis; also inhib G1-S
Familial polyposis
Gene product inhibits going from G1-S (not TGF beta or p53)
InfoAnswerdetails
Regulates nuclear transcription (not VHL)
Li Fraumeni
OSTEOSARCOMA, breast carcinoma, retinoblastoma
Breast, ovary carcinomas
Regulates nuclear transcription (not WT1)
Syndrome of Cerebellar hemang, retinal angioma, bilat RCC and PCC
Wilms' tumor
Gene product regulates DNA repair
Cerebellar hemang, retinal angioma, bilat RCC and PCC

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Created Nov 27, 2012ReportNominate
Tags:Nintendo, detail, gene, table