Papulosquamous and Skin neoplasia

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Characteristics Answerdetails
melanocytic flesh􏰁colored papules􏰀(not􏰀pigmented!);􏰀confined􏰀to􏰀clusters􏰀within􏰀the􏰀dermisnevus
red􏰀scaling (hyperkeratosis)􏰀papules􏰀with􏰀'sandpaper􏰀feel'􏰀surface; epidermal􏰀atypia􏰀that􏰀does􏰀NOT􏰀involve􏰀full􏰁thickness􏰀&􏰀parakeratosactinic keratosis; percursor to SCC
firm,􏰀dermal nodular􏰀scars; proliferation􏰀of􏰀connective􏰀tissue􏰀(collagen)􏰀as􏰀a􏰀fibroblastic􏰀response􏰀to􏰀injury (e.g.􏰀ear􏰀piercing), Blacksif not bulging-> hypertrophic scar
Multiple􏰀EICs; FAP, mult soft tissue tumorsgardner's syndrome
Bug in guttate psoriasisGroup A strep
Multiple􏰀tiny􏰀white/yellow􏰀papules􏰀in􏰀newborns; variant of EIC, from diff part of hair follicle
􏰀increase􏰀of􏰀melanin􏰀pigment􏰀in􏰀basal keratinocytes,􏰀NO􏰀melanocyte􏰀hyperplasiafreckles
Variant􏰀of􏰀SCC􏰀with􏰀sudden􏰀onset􏰀&􏰀rapid􏰀growthmay resemble BCC
multiple internal fibromas; cafe au laitaka Von Recksomething
firm, brown􏰀nodules􏰀on􏰀legs􏰀of􏰀middle􏰁aged􏰀women with􏰀'dimple􏰀sign'􏰀on􏰀compression; proliferation􏰀of􏰀fibroblasts􏰀in􏰀dermis (does􏰀NOTbenign fibrous histioma
bcc with scar-like plaques, called 'infiltrative'morpheaform
Characteristic􏰀parakeratosis􏰀(retention􏰀of􏰀nuclei); Epidermal􏰀proliferation􏰀with􏰀acanthosis􏰀(thickening); Spongiosis􏰀(epidermal􏰀edema)􏰀with􏰀􏰀
Most􏰀common􏰀type􏰀of􏰀melanoma􏰀in􏰀dark􏰁skinned􏰀patients􏰀(AA);􏰀occurs􏰀on􏰀hands􏰀&􏰀feet; thick epidermis on feetAcral lentiginous melanoma, ALM
precursor􏰀lesion􏰀to􏰀LMMfreckle, lentigo maligna
halo nevi associated with what 2 conditions in adults
benign proliferation of squamous cellsseborrheic keratosis
lacy􏰀Wickham's􏰀striae
'in situ SCC'Associated􏰀with􏰀arsenic exposure􏰀&􏰀increased􏰀incidence􏰀of􏰀internal􏰀malignancy; has not invaded dermis yet (in-situ)
Precursor􏰀lesion to􏰀malignant􏰀melanoma; flat at birth, thickens with agenevus
multiple large􏰀nevi􏰀with􏰀irregular pigmentation􏰀&􏰀irregular borders; irregularly􏰀'fried􏰁egg'􏰀looking􏰀melanocytes􏰀in􏰀the􏰀epidermal􏰁dermal􏰀j
pigmented tumors of skin have what cellular originmelanocyte
Characteristics Answerdetails
Asymptomatic small􏰀flat􏰁topped􏰀papules􏰀that􏰀spread􏰀along􏰀line􏰀of􏰀Blaschko on􏰀armLS
dome􏰁shaped dermal􏰀cyst􏰀(tumor􏰀containing􏰀liquid) with􏰀central􏰀puncta􏰀(opening)􏰀leaking􏰀cheesy􏰀 material; epithelial􏰀cyst􏰀(a􏰀real􏰀cystepidermal inclusion cyst, 'sebaceous cyst'
'pearly'􏰀papule􏰀with􏰀telangiectasia􏰀(dilated􏰀vessels); clusters􏰀of􏰀dark􏰀cells􏰀with􏰀palisading􏰀of􏰀nuclei; NO METSbasal cell carcinoma
Well􏰁defined,􏰀non􏰁itchy,􏰀red􏰀plaques􏰀(flat􏰀papules); Thick 'silvery􏰁white'􏰀scales􏰀&􏰀erythematous􏰀base
fleshy,􏰀pedunculated,􏰀papillomatous􏰀lesions; central􏰀connective􏰀tissue􏰀core􏰀covered􏰀by􏰀epithelial􏰀cells􏰀(aka􏰀fibro􏰁epithelial􏰀polyp); 'skiacrochordon, benign, epithelial origin
frecklesmelanocytic
Melanoma with worst prognosis;minvasive􏰀in􏰀dermis without􏰀intra􏰁epidermal􏰀involvement
hairy brown patch, fake nevus
multiple􏰀small􏰀SK􏰀on􏰀malar􏰀area of􏰀face􏰀in􏰀darker􏰀skinVariant of SK, Dermatosis papulosa nigra
Asymptomatic flesh􏰁colored􏰀papules􏰀(tiny􏰀bumps)􏰀that􏰀koebnerize; flexor􏰀surfaces of􏰀arms,􏰀trunk􏰀&􏰀penisLN
Melanotic􏰀accumulation􏰀in􏰀mouth,􏰀lips,􏰀hands,􏰀genitalia; Polyps􏰀of􏰀colon􏰀&􏰀small􏰀intestine; ADpuetz jeghers
Predisposing factors to BCCSame as SCC
single􏰀itchy 'herald􏰀patch' plaques􏰀on􏰀trunk; then multiple􏰀symmetrical eruptions􏰀with􏰀'Christmas􏰀tree'􏰀pattern; negative RPR and VDRL pityriasis rosea
common molejxnal, intradermal, compound
invasive proliferation􏰀of􏰀melanocytes􏰀into􏰀dermislentigo maligna melanoma
EIC on scalppilar cyst
brown􏰀macules􏰀on􏰀sun􏰁exposed􏰀skin; limited melanocyte􏰀hyperplasia in􏰀basal epidermisage spots
Predisposing factors to SCCSame as BCC
organized brown􏰀nodules􏰀of􏰀fibroblasts􏰀invading􏰀the􏰀SC􏰀tissue (vs dermatofibroma, which stays in dermis, IE, is not malignant)dermatofibrosarcoma protuberans; malignant
brown􏰀papules􏰀(raised􏰀&􏰀pigmented);􏰀present􏰀at􏰀both at􏰀the􏰀epidermal􏰁dermal􏰀junction􏰀 &􏰀in􏰀the􏰀dermisnevus
brown􏰀macules (not􏰀raised!);􏰀confined􏰀to􏰀the􏰀epidermal􏰁dermal􏰀junctionnevus
Characteristics Answerdetails
Best indicator of melanoma prognosisBreslow's thickness
leser trelat assoc withor internal malignancy in general
scaling,􏰀indurated,􏰀ulcerated􏰀nodule􏰀'sore􏰀that􏰀doesn't􏰀heal'; islands􏰀of􏰀neoplastic􏰀epidermal􏰀cells􏰀with􏰀'keratin􏰀pearls'; can metssquamous cell carcinoma
LP occuring􏰀on􏰀lower􏰀legs,􏰀extremely􏰀extremely􏰀itchyhypertrophic lichen planus
small􏰀red􏰀papules􏰀on􏰀skins; proliferation􏰀of􏰀dilated􏰀capillaries􏰀&􏰀venules􏰀in􏰀lobules; benignacq cherry....
Well defined epidermal lesions with scales & symmetrical􏰀rashes (general term)PR, psoriasis, LP, LS, LN
'slit􏰁like'􏰀spaces􏰀with􏰀RBC􏰀extravasation􏰀&􏰀hemosiderin􏰀deposition (greek men, HIV pts)HHV8
Helper cells in psoriasisvs Th2s in eczematous conditions
Melanoma lacking pigmentation, spreading via nervesAmelanotic melanoma, hard to dx
speckled patch acquired in childhoodbenign, but may degenerate to melanoma
Precursor􏰀lesion􏰀to􏰀SCC􏰀due􏰀to􏰀excessive􏰀exposure􏰀to􏰀sunlightactinic keratosis; squamous cell proliferation
retention of nuclei within the keratinosisparakeratosis; psoriasis
rodent ulcer
#1 soft tissue tumor in adultsbenign
Most􏰀common􏰀subtype of􏰀melanoma;􏰀occurs􏰀on􏰀trunk of􏰀men􏰀&􏰀posterior􏰀thigh of􏰀womensuperficial spreading melanoma
Which surfaces have psoriasis
soft tissue tumors are of what origin
explosive onset of seborrheic keratosisleser, trelat, assoc with gastric adenocarcinoma
virus assoc with Kaposifound in AIDS (HIV)
benign􏰀pigmented􏰀skin􏰀neoplasm􏰀that􏰀appears􏰀'stuck􏰁on'􏰀&􏰀verrucous; acanthosis􏰀with􏰀'horn􏰀pseudocyst'seborrheic keratosis

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Created Oct 18, 2012ReportNominate
Tags:detail, skin, stuff