Papulosquamous and Skin neoplasia

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Characteristics Answerdetails
firm, brown􏰀nodules􏰀on􏰀legs􏰀of􏰀middle􏰁aged􏰀women with􏰀'dimple􏰀sign'􏰀on􏰀compression; proliferation􏰀of􏰀fibroblasts􏰀in􏰀dermis (does􏰀NOTbenign fibrous histioma
single􏰀itchy 'herald􏰀patch' plaques􏰀on􏰀trunk; then multiple􏰀symmetrical eruptions􏰀with􏰀'Christmas􏰀tree'􏰀pattern; negative RPR and VDRL pityriasis rosea
Characteristic􏰀parakeratosis􏰀(retention􏰀of􏰀nuclei); Epidermal􏰀proliferation􏰀with􏰀acanthosis􏰀(thickening); Spongiosis􏰀(epidermal􏰀edema)􏰀with􏰀􏰀
multiple internal fibromas; cafe au laitaka Von Recksomething
multiple􏰀small􏰀SK􏰀on􏰀malar􏰀area of􏰀face􏰀in􏰀darker􏰀skinVariant of SK, Dermatosis papulosa nigra
EIC on scalppilar cyst
Variant􏰀of􏰀SCC􏰀with􏰀sudden􏰀onset􏰀&􏰀rapid􏰀growthmay resemble BCC
firm,􏰀dermal nodular􏰀scars; proliferation􏰀of􏰀connective􏰀tissue􏰀(collagen)􏰀as􏰀a􏰀fibroblastic􏰀response􏰀to􏰀injury (e.g.􏰀ear􏰀piercing), Blacksif not bulging-> hypertrophic scar
Melanoma with worst prognosis;minvasive􏰀in􏰀dermis without􏰀intra􏰁epidermal􏰀involvement
Multiple􏰀tiny􏰀white/yellow􏰀papules􏰀in􏰀newborns; variant of EIC, from diff part of hair follicle
Predisposing factors to BCCSame as SCC
brown􏰀papules􏰀(raised􏰀&􏰀pigmented);􏰀present􏰀at􏰀both at􏰀the􏰀epidermal􏰁dermal􏰀junction􏰀 &􏰀in􏰀the􏰀dermisnevus
LP occuring􏰀on􏰀lower􏰀legs,􏰀extremely􏰀extremely􏰀itchyhypertrophic lichen planus
organized brown􏰀nodules􏰀of􏰀fibroblasts􏰀invading􏰀the􏰀SC􏰀tissue (vs dermatofibroma, which stays in dermis, IE, is not malignant)dermatofibrosarcoma protuberans; malignant
soft tissue tumors are of what origin
red􏰀scaling (hyperkeratosis)􏰀papules􏰀with􏰀'sandpaper􏰀feel'􏰀surface; epidermal􏰀atypia􏰀that􏰀does􏰀NOT􏰀involve􏰀full􏰁thickness􏰀&􏰀parakeratosactinic keratosis; percursor to SCC
'pearly'􏰀papule􏰀with􏰀telangiectasia􏰀(dilated􏰀vessels); clusters􏰀of􏰀dark􏰀cells􏰀with􏰀palisading􏰀of􏰀nuclei; NO METSbasal cell carcinoma
melanocytic flesh􏰁colored papules􏰀(not􏰀pigmented!);􏰀confined􏰀to􏰀clusters􏰀within􏰀the􏰀dermisnevus
􏰀increase􏰀of􏰀melanin􏰀pigment􏰀in􏰀basal keratinocytes,􏰀NO􏰀melanocyte􏰀hyperplasiafreckles
retention of nuclei within the keratinosisparakeratosis; psoriasis
Predisposing factors to SCCSame as BCC
Characteristics Answerdetails
bcc with scar-like plaques, called 'infiltrative'morpheaform
Most􏰀common􏰀subtype of􏰀melanoma;􏰀occurs􏰀on􏰀trunk of􏰀men􏰀&􏰀posterior􏰀thigh of􏰀womensuperficial spreading melanoma
rodent ulcer
brown􏰀macules (not􏰀raised!);􏰀confined􏰀to􏰀the􏰀epidermal􏰁dermal􏰀junctionnevus
multiple large􏰀nevi􏰀with􏰀irregular pigmentation􏰀&􏰀irregular borders; irregularly􏰀'fried􏰁egg'􏰀looking􏰀melanocytes􏰀in􏰀the􏰀epidermal􏰁dermal􏰀j
Asymptomatic small􏰀flat􏰁topped􏰀papules􏰀that􏰀spread􏰀along􏰀line􏰀of􏰀Blaschko on􏰀armLS
fleshy,􏰀pedunculated,􏰀papillomatous􏰀lesions; central􏰀connective􏰀tissue􏰀core􏰀covered􏰀by􏰀epithelial􏰀cells􏰀(aka􏰀fibro􏰁epithelial􏰀polyp); 'skiacrochordon, benign, epithelial origin
Best indicator of melanoma prognosisBreslow's thickness
common molejxnal, intradermal, compound
hairy brown patch, fake nevus
pigmented tumors of skin have what cellular originmelanocyte
Multiple􏰀EICs; FAP, mult soft tissue tumorsgardner's syndrome
Asymptomatic flesh􏰁colored􏰀papules􏰀(tiny􏰀bumps)􏰀that􏰀koebnerize; flexor􏰀surfaces of􏰀arms,􏰀trunk􏰀&􏰀penisLN
virus assoc with Kaposifound in AIDS (HIV)
Precursor􏰀lesion􏰀to􏰀SCC􏰀due􏰀to􏰀excessive􏰀exposure􏰀to􏰀sunlightactinic keratosis; squamous cell proliferation
Melanotic􏰀accumulation􏰀in􏰀mouth,􏰀lips,􏰀hands,􏰀genitalia; Polyps􏰀of􏰀colon􏰀&􏰀small􏰀intestine; ADpuetz jeghers
precursor􏰀lesion􏰀to􏰀LMMfreckle, lentigo maligna
invasive proliferation􏰀of􏰀melanocytes􏰀into􏰀dermislentigo maligna melanoma
Bug in guttate psoriasisGroup A strep
small􏰀red􏰀papules􏰀on􏰀skins; proliferation􏰀of􏰀dilated􏰀capillaries􏰀&􏰀venules􏰀in􏰀lobules; benignacq cherry....
speckled patch acquired in childhoodbenign, but may degenerate to melanoma
Characteristics Answerdetails
Well􏰁defined,􏰀non􏰁itchy,􏰀red􏰀plaques􏰀(flat􏰀papules); Thick 'silvery􏰁white'􏰀scales􏰀&􏰀erythematous􏰀base
Most􏰀common􏰀type􏰀of􏰀melanoma􏰀in􏰀dark􏰁skinned􏰀patients􏰀(AA);􏰀occurs􏰀on􏰀hands􏰀&􏰀feet; thick epidermis on feetAcral lentiginous melanoma, ALM
'in situ SCC'Associated􏰀with􏰀arsenic exposure􏰀&􏰀increased􏰀incidence􏰀of􏰀internal􏰀malignancy; has not invaded dermis yet (in-situ)
#1 soft tissue tumor in adultsbenign
scaling,􏰀indurated,􏰀ulcerated􏰀nodule􏰀'sore􏰀that􏰀doesn't􏰀heal'; islands􏰀of􏰀neoplastic􏰀epidermal􏰀cells􏰀with􏰀'keratin􏰀pearls'; can metssquamous cell carcinoma
halo nevi associated with what 2 conditions in adults
leser trelat assoc withor internal malignancy in general
frecklesmelanocytic
Helper cells in psoriasisvs Th2s in eczematous conditions
lacy􏰀Wickham's􏰀striae
dome􏰁shaped dermal􏰀cyst􏰀(tumor􏰀containing􏰀liquid) with􏰀central􏰀puncta􏰀(opening)􏰀leaking􏰀cheesy􏰀 material; epithelial􏰀cyst􏰀(a􏰀real􏰀cystepidermal inclusion cyst, 'sebaceous cyst'
Melanoma lacking pigmentation, spreading via nervesAmelanotic melanoma, hard to dx
explosive onset of seborrheic keratosisleser, trelat, assoc with gastric adenocarcinoma
benign proliferation of squamous cellsseborrheic keratosis
benign􏰀pigmented􏰀skin􏰀neoplasm􏰀that􏰀appears􏰀'stuck􏰁on'􏰀&􏰀verrucous; acanthosis􏰀with􏰀'horn􏰀pseudocyst'seborrheic keratosis
Which surfaces have psoriasis
brown􏰀macules􏰀on􏰀sun􏰁exposed􏰀skin; limited melanocyte􏰀hyperplasia in􏰀basal epidermisage spots
Well defined epidermal lesions with scales & symmetrical􏰀rashes (general term)PR, psoriasis, LP, LS, LN
'slit􏰁like'􏰀spaces􏰀with􏰀RBC􏰀extravasation􏰀&􏰀hemosiderin􏰀deposition (greek men, HIV pts)HHV8
Precursor􏰀lesion to􏰀malignant􏰀melanoma; flat at birth, thickens with agenevus

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