Can you name the heart & circulation drug?

created by klamberry
  • Enter a drug in the box below
  • Correctly named drugs will show up below
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Atrial Fibrillation
anti-thrombotic 
anti-thrombotic if additional risk factors 
slows AV node, minor vagal response, slow onset (side fx: heart block, any arrhythmia) 
slows AV node and makes it more refractory (class 4, side fx: negative inotrope, X ind.: beta blocker) 
slows AV node and makes it more refractory (class 4, side fx: negative inotrope, X ind.: beta blocker) 
slows AV node by reducing sympathetic stimulation 
electric solution for AF 
restores sinus rhythm and slows AV node, prophylactic (multiblock, side fx: variable, hypotension, bradycardia, skin, pulmonary, and thyroid toxicity) 
restores sinus rhythm and slows AV node (inward K block, nonselective beta block, side fx: long QT) 
*restores sinus rhythm and slows AV node (class IC, side fx: conduction block, bradycardia) 
*restores sinus rhythm and slows AV node, patients with good ventricle (multiblock, side fx: less than other multiblock) 
SVT
temporary AV node block, diagnostic (X indic.: asthma) 
slows AV node and makes it more refractory (class 4, side fx: negative inotrope) 
slows AV node and makes it more refractory (class 4, side fx: negative inotrope) 
chronic 1st choice: slows AV node by reducing sympathetic stimulation 
surgical solution 
restores sinus rhythm and slows AV node, prophylactic (multiblock, side fx: variable, hypotension, bradycardia, skin, pulmonary, and thyroid toxicity) 
restores sinus rhythm and slows AV node (class 1a, side fx: pro-arrhythmia, anticholinergic) 
restores sinus rhythm (class 3, side fx: long QT) 
VT
temporary AV node block, diagnostic (X indic.: asthma) 
acute, monomorphic ischemic, decreases automaticity (class 1b, hepatic metabolism, side fx: seizures, CV collapse) 
acute, any monomorphic, prolongs action potential (class 1a, side fx: pro-arrhythmia, anticholinergic) 
acute or chronic, slows automaticity (multiblock, side fx: variable, hypotension, bradycardia, skin, pulmonary, and thyroid toxicity) 
chronic, lengthens action potential, decreases automaticity (inward K block, nonselective beta block, side fx: long QT) 
*chronic, reduced conductivity in ventricle (class IC, side fx: conduction block, bradycardia) 
electric solution 
Sympathetic response
sympathomimetic, resuscitation, counters anaphylaxis, local vasoconstriction, released by adrenal medulla 
released by SNS post-ganglionic neuron for heart 
doesn't cross BBB, increases blood pressure and cardiac output 
acute treatment of bradycardia, elevates heart rate and vasodilates 
causes intense vasoconstriction, used as a decongestant and vasopressor 
mixed alpha/beta effect, indirect release of NE to cause SNS symptoms, used as a stimulant, decongestant, and appetite suppressant 
bronchodilator, may cause heart palpitations and tremor 
anti-muscarinic, used in cardiac resuscitation, hot as a hair, blind as a bat, DRY AS A BONE, red as a beet, mad as a hatter 
inhaled as a bronchodilator, anti-muscarinic 
Parasympathetic response
vasodilation, treatment for pheochromocytoma 
antihypertensive, causes vasoconstriction with little effect on heart 
used to treat glaucoma, myasthenia gravis and to reverse neuromuscular blockers 
quick acting, causes muscle fasciculations then paralysis, unreversible by AchEI 
causes paralysis, reversible by AchEI 
complicated response, SNS and PSNS depending on organ tone and dose (blockade at high dose) 
treats hypertension but as a last resort, decreases SNS 
anti-hypertensive, reduces heart contractility and vasodilates 
Hypertension
reduces vasoconstriction, increases Na/H2O secretion to drop BP (side fx: angioedema, cough, hyperkalemia, worse kidney) 
reduces vasoconstriction, increases Na/H2O secretion to drop BP (side fx: hyperkalemia) 
causes vasodilation to reduce afterload, some reduce heart contractility as well (side fx: bradycardia, hypotension) 
blocks sympathetic response preventing elevated contractility, causes vasoconstriction 
increases H2O excretion to reduce blood volume and BP (side fx: maybe hyperkalemia) 
healthy diet, exercise 
restrict EtOH, restrict Na intake, smoking cessation, control dyslipidemia, CPAP 
Cardiac failure
to reduce fluid overload/pulmonary edema (side fx: hypokalemia) 
1st line reduces vasoconstriction and afterload, increases Na/H2O secretion to drop BP (side fx: angioedema, cough, hyperkalemia, worse kidney) 
1st line reduce chronic sympathetic stimulation on heart 
2nd line increased contractility, reduces hospital admissions but not mortality (side fx: arrhythmia, increased AV block, yellow-green halo) 
2nd line increases H2O and Na secretion (side fx: hyperkalemia) 
only if other drugs fail, vasodilates to reduce afterload 
electrical solution, provides a shock if heart enters arrhythmia 
if a suitable candidate, extends lifespan by 10-15 years 
exercise 
smoking cessation, reduce Na consumption, control DM, fluid restriction 
Dyslipidemia
anti-HMG-CoA causing upregulation of LDLr and cholesterol excretion, LDL-C down by ~33% (side fx: CK elevated, myalgia, rhabdomyolysis, elevated LFT) 
raises HDL-C, inhibits VLDL secretion, activates LPL for VLDL clearance 
multiple sites of action, reduces LDL-C, better at lowering TG (side fx: potentiates warfarin, elevated LFT) 
safe alternative for reducing TG 
blocks cholesterol re-uptake from intestine, LDL-C down by ~15% 
blocks cholesterol uptake by sequestration 
antioxidant for treatment of homozygous familial hypercholesterolemia 
Coronary artery disease
if coronary angioplasty is unavailable, to remove plaque 
common anti-platelet, provided upon MI admission 
anti-platelet if other is contraindicated 
anti-coagulant administered upon MI admission 
control dyslipidemia 
control hypertension 
vasodilation for angina relief prn, provided upon MI admission 
Bradycardia
acute treatment, stimulates SNS response 
acute treatment, anti-muscarinic/anti-PSNS response 
acute treatment, beta agonist stimulates heart rate 
chronic treatment 
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Heart & Circulation drugs Quiz

  1. by klamberry
  • Created Feb 20, 2011 in Science
  • Game Plays 111

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