Goljan 5 of X: Autoimmune/neoplastic Dz marker

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Can you name the Goljan 5 of X: Disease markers and genes

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Anti-thyroperoxidase antibodies
Inversion c.16
Anti-endomysial IgA
Causes centrilobular necrosis and fatty change of the liver
t(8;21)
Auto-antiobdy seen in rheumatoid arthritis
CALLA is a positive indicator in...
Pleomorphic astrocytes with brisk activity and necrosis
Receptor targeted by tratuzumab
C-kit
Gene mutated in MEN 2a/2b
Anti-Yo, Anti-P|Q, Anti-Hu
Anti-GBM antibodies
S-100 tumor marker
Ki67 fraction >99%
AFP tumor marker
Auto-antibody seen in Wegener's granulomatosis
Anti-SS-B (La) antibodies
Tumor marker for neuroblastoma
BRAF V600E
Pseudorosettes with GFAP positive processes
Gene involved in t(14;18)
What is translocation of mantle cell lymphoma?
CEA tumor marker
AD mutation in p53 gene
NSE, Chromogranin, Synaptophysin, S100 (+)
Cause of liver angiosarcoma
Anti-LKM antibodies
Gene mutated in NF2
HVA in urine
Auto-antiobdy seen in Churg-Strauss syndrome
Auto-antiobdy seen in Grave's disease
Homer-wright rosettes
Anti-tissue transglutiminase IgA
Auto-antiobdy seen in polymyositis
Anti-islet cell antibodies
Anti-ACh receptor antibodies
Anti-proteinase 3 antibodies
t(14;18)
HintAnswer
AD mutation in APC gene
14-3-3
Deficiency of C1 esterase inhibitor
Anti-MPO antibodies
Auto-antibody seen in microscopic polyangiitis
Anti-desmoglein antibodies
Auto-antiobdy seen in autoimmune hepatitis
CD10 is a positive indicator in...
Anti-giladin IgA
Anti-TSH receptor antibodies
AD mutation in MLH1/MSH2
Mutated in Li-Fraumani syndrome
Mutated in familial adenomatous polyposis
C-MYC implicated in what cancer
t(8;14)
Cystic brain tumor with granular eosinophilic bodies
Analine dyes
Anti-Sm antibodies
c-Myc activating cancer leads to EWSFL1 over-production
Anti-glutamate decarboxylase antibodies
Anti-DNA topoisomerase 1 antibodies
Anti-SS-A (Ro) antibodies
MCC1 complement deficiency
Elevated bombesin
BCR-ABL fusion gene
DPC mutation
LDH tumor marker
Rosenthal fibers
Anti-dsDNA antibodies
Anti-smooth muscle antibodies
N-MYC implicated in what cancer
Anti-nuclear antibodies
Anti-ribonucleoprotein antibodies
High urinary HVA/VMA + N-Myc
DCC mutation
Missing enzyme to degrade C3 and C4 convertase on RBCs
Gene is involved in t(11;14)
Anti-voltage-gated Ca2+ channel antibodies
Anti-SCL 70 antibodies
HintAnswer
Cells that stain (+) for synaptophysin
AD mutation of NF1
Hypocretin-1
Defect in decay accelerating factor (DAF)
t(15;17)
Auto-antiobdy seen in Goodpasture syndrome
Anti-IgG antibodies
Anti-microsomal antibodies
Inheritance of hereditary angioedema
ERB-B2 gene
Auto-antiobdy seen in seen in PBC
Growth factor affected by osteosarcoma
t(8;14) affects what gene
Elevated tartrate-resistant acid phosphatase
Anti-U1 RNP antibodies
Complement deficiency + S. pneumo septicemia + lupus-like syndrome
Anti-Jo-1 antibodies
Anti-parietal cell antibodies
CA 125 tumor marker
Anti-histone antibodies
Anti-intrinsic factor antibodies
Anti-mitochondrial antibodies
Anti-centormere antibodies
t(11;22)
HPV viral protein E6 target
Cancer of CyclinD dysregulation
PML/RARa gene created by
Auto-antiobdy seen in CREST syndrome
t(9;22)
Thorotrast, arsenic, polyvinyl chloride
Anti-thyroglobulin antibodies
Auto-antiobdy seen in mixed connective tissue disease
Anti-insulin antibodies
t(11;14)
Auto-antiobdy seen in drug-induced lupus
CA 15-3 tumor marker
Spindle cells with hair-like glial processes
HPV viral protein E7 target
CA 19-9 tumor marker

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Created Jan 15, 2014ReportNominate
Tags:disease, gene, marker