Goljan 5 of X: Autoimmune/neoplastic Dz marker

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Can you name the Goljan 5 of X: Disease markers and genes

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Auto-antibody seen in microscopic polyangiitis
Auto-antiobdy seen in Goodpasture syndrome
CD10 is a positive indicator in...
Cancer of CyclinD dysregulation
Anti-IgG antibodies
CA 15-3 tumor marker
CALLA is a positive indicator in...
AD mutation of NF1
HVA in urine
Cause of liver angiosarcoma
Anti-islet cell antibodies
t(9;22)
Causes centrilobular necrosis and fatty change of the liver
Anti-glutamate decarboxylase antibodies
Hypocretin-1
Auto-antiobdy seen in rheumatoid arthritis
Anti-nuclear antibodies
LDH tumor marker
Mutated in familial adenomatous polyposis
Gene is involved in t(11;14)
AD mutation in MLH1/MSH2
N-MYC implicated in what cancer
Anti-smooth muscle antibodies
Cells that stain (+) for synaptophysin
Auto-antiobdy seen in seen in PBC
t(14;18)
S-100 tumor marker
Thorotrast, arsenic, polyvinyl chloride
Anti-endomysial IgA
NSE, Chromogranin, Synaptophysin, S100 (+)
Anti-thyroperoxidase antibodies
Anti-Sm antibodies
HPV viral protein E7 target
Gene involved in t(14;18)
DPC mutation
BCR-ABL fusion gene
t(8;14)
Auto-antiobdy seen in mixed connective tissue disease
HPV viral protein E6 target
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Anti-mitochondrial antibodies
Anti-histone antibodies
Anti-tissue transglutiminase IgA
Anti-SS-A (Ro) antibodies
t(11;22)
AD mutation in APC gene
Anti-giladin IgA
Auto-antiobdy seen in Churg-Strauss syndrome
Anti-Jo-1 antibodies
t(8;14) affects what gene
Auto-antiobdy seen in CREST syndrome
Anti-DNA topoisomerase 1 antibodies
AD mutation in p53 gene
Growth factor affected by osteosarcoma
t(8;21)
Anti-TSH receptor antibodies
Auto-antibody seen in Wegener's granulomatosis
Auto-antiobdy seen in polymyositis
Gene mutated in NF2
AFP tumor marker
Auto-antiobdy seen in autoimmune hepatitis
Pseudorosettes with GFAP positive processes
Anti-proteinase 3 antibodies
Receptor targeted by tratuzumab
Anti-centormere antibodies
Elevated tartrate-resistant acid phosphatase
Anti-U1 RNP antibodies
Anti-dsDNA antibodies
Inheritance of hereditary angioedema
What is translocation of mantle cell lymphoma?
Anti-intrinsic factor antibodies
Anti-Yo, Anti-P|Q, Anti-Hu
Anti-parietal cell antibodies
Defect in decay accelerating factor (DAF)
Anti-SS-B (La) antibodies
Anti-MPO antibodies
t(11;14)
Rosenthal fibers
CA 19-9 tumor marker
HintAnswer
Anti-insulin antibodies
Inversion c.16
Pleomorphic astrocytes with brisk activity and necrosis
DCC mutation
BRAF V600E
Complement deficiency + S. pneumo septicemia + lupus-like syndrome
ERB-B2 gene
High urinary HVA/VMA + N-Myc
14-3-3
Anti-GBM antibodies
MCC1 complement deficiency
Gene mutated in MEN 2a/2b
Anti-ACh receptor antibodies
Missing enzyme to degrade C3 and C4 convertase on RBCs
CA 125 tumor marker
Anti-desmoglein antibodies
t(15;17)
C-MYC implicated in what cancer
Auto-antiobdy seen in Grave's disease
Anti-LKM antibodies
Mutated in Li-Fraumani syndrome
Tumor marker for neuroblastoma
Anti-voltage-gated Ca2+ channel antibodies
Analine dyes
Elevated bombesin
Ki67 fraction >99%
PML/RARa gene created by
Anti-SCL 70 antibodies
Cystic brain tumor with granular eosinophilic bodies
Spindle cells with hair-like glial processes
Deficiency of C1 esterase inhibitor
Anti-thyroglobulin antibodies
Auto-antiobdy seen in drug-induced lupus
Homer-wright rosettes
Anti-ribonucleoprotein antibodies
C-kit
Anti-microsomal antibodies
c-Myc activating cancer leads to EWSFL1 over-production
CEA tumor marker

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