Goljan 5 of X: Autoimmune/neoplastic Dz marker

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Can you name the Goljan 5 of X: Disease markers and genes

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Anti-Sm antibodies
CD10 is a positive indicator in...
Gene mutated in NF2
Missing enzyme to degrade C3 and C4 convertase on RBCs
t(15;17)
Anti-smooth muscle antibodies
Anti-mitochondrial antibodies
14-3-3
Elevated tartrate-resistant acid phosphatase
Thorotrast, arsenic, polyvinyl chloride
Anti-glutamate decarboxylase antibodies
Anti-IgG antibodies
AD mutation in p53 gene
t(9;22)
C-kit
HVA in urine
Auto-antiobdy seen in seen in PBC
Receptor targeted by tratuzumab
t(11;14)
CA 125 tumor marker
Cells that stain (+) for synaptophysin
Complement deficiency + S. pneumo septicemia + lupus-like syndrome
t(8;14) affects what gene
Anti-microsomal antibodies
Rosenthal fibers
HPV viral protein E7 target
Auto-antiobdy seen in autoimmune hepatitis
MCC1 complement deficiency
t(8;21)
Anti-ACh receptor antibodies
DCC mutation
Anti-histone antibodies
CALLA is a positive indicator in...
Anti-parietal cell antibodies
Anti-nuclear antibodies
Anti-islet cell antibodies
Gene mutated in MEN 2a/2b
Gene is involved in t(11;14)
Anti-insulin antibodies
HintAnswer
Anti-ribonucleoprotein antibodies
Auto-antiobdy seen in Grave's disease
Anti-SS-B (La) antibodies
AD mutation in MLH1/MSH2
Mutated in familial adenomatous polyposis
N-MYC implicated in what cancer
High urinary HVA/VMA + N-Myc
Anti-endomysial IgA
Anti-Yo, Anti-P|Q, Anti-Hu
CA 15-3 tumor marker
Anti-tissue transglutiminase IgA
S-100 tumor marker
PML/RARa gene created by
DPC mutation
Anti-LKM antibodies
Auto-antibody seen in Wegener's granulomatosis
Cystic brain tumor with granular eosinophilic bodies
Anti-DNA topoisomerase 1 antibodies
Deficiency of C1 esterase inhibitor
HPV viral protein E6 target
Anti-thyroperoxidase antibodies
Anti-SS-A (Ro) antibodies
Causes centrilobular necrosis and fatty change of the liver
Auto-antiobdy seen in mixed connective tissue disease
Auto-antiobdy seen in CREST syndrome
Cancer of CyclinD dysregulation
Analine dyes
t(11;22)
Growth factor affected by osteosarcoma
Anti-intrinsic factor antibodies
CA 19-9 tumor marker
Elevated bombesin
Auto-antiobdy seen in Churg-Strauss syndrome
Auto-antiobdy seen in drug-induced lupus
Auto-antiobdy seen in polymyositis
Auto-antiobdy seen in Goodpasture syndrome
Anti-SCL 70 antibodies
Anti-thyroglobulin antibodies
t(8;14)
HintAnswer
Mutated in Li-Fraumani syndrome
Cause of liver angiosarcoma
ERB-B2 gene
Anti-Jo-1 antibodies
BRAF V600E
Gene involved in t(14;18)
CEA tumor marker
Spindle cells with hair-like glial processes
Anti-giladin IgA
Pseudorosettes with GFAP positive processes
AD mutation in APC gene
Anti-centormere antibodies
AFP tumor marker
BCR-ABL fusion gene
Anti-desmoglein antibodies
Anti-U1 RNP antibodies
Defect in decay accelerating factor (DAF)
What is translocation of mantle cell lymphoma?
Anti-proteinase 3 antibodies
Anti-TSH receptor antibodies
NSE, Chromogranin, Synaptophysin, S100 (+)
Ki67 fraction >99%
Auto-antibody seen in microscopic polyangiitis
t(14;18)
Hypocretin-1
Anti-MPO antibodies
Anti-voltage-gated Ca2+ channel antibodies
LDH tumor marker
AD mutation of NF1
Pleomorphic astrocytes with brisk activity and necrosis
Inversion c.16
Auto-antiobdy seen in rheumatoid arthritis
c-Myc activating cancer leads to EWSFL1 over-production
Anti-GBM antibodies
Inheritance of hereditary angioedema
C-MYC implicated in what cancer
Tumor marker for neuroblastoma
Homer-wright rosettes
Anti-dsDNA antibodies

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Created Jan 15, 2014ReportNominate
Tags:disease, gene, marker