Goljan 5 of X: Autoimmune/neoplastic Dz marker

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Can you name the Goljan 5 of X: Disease markers and genes

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Anti-endomysial IgA
Auto-antiobdy seen in Goodpasture syndrome
Anti-IgG antibodies
NSE, Chromogranin, Synaptophysin, S100 (+)
C-MYC implicated in what cancer
Thorotrast, arsenic, polyvinyl chloride
Anti-glutamate decarboxylase antibodies
Tumor marker for neuroblastoma
Anti-mitochondrial antibodies
Anti-TSH receptor antibodies
t(14;18)
Auto-antiobdy seen in CREST syndrome
Anti-proteinase 3 antibodies
CEA tumor marker
Anti-SCL 70 antibodies
Anti-histone antibodies
Anti-smooth muscle antibodies
Auto-antibody seen in Wegener's granulomatosis
Anti-DNA topoisomerase 1 antibodies
Anti-thyroglobulin antibodies
ERB-B2 gene
CA 125 tumor marker
t(8;14) affects what gene
Anti-centormere antibodies
Anti-nuclear antibodies
Anti-ACh receptor antibodies
Causes centrilobular necrosis and fatty change of the liver
Missing enzyme to degrade C3 and C4 convertase on RBCs
Anti-intrinsic factor antibodies
Growth factor affected by osteosarcoma
Anti-dsDNA antibodies
t(9;22)
C-kit
Auto-antiobdy seen in Grave's disease
14-3-3
Complement deficiency + S. pneumo septicemia + lupus-like syndrome
Elevated tartrate-resistant acid phosphatase
Anti-islet cell antibodies
Anti-thyroperoxidase antibodies
HintAnswer
CA 19-9 tumor marker
Gene is involved in t(11;14)
Anti-insulin antibodies
Anti-Yo, Anti-P|Q, Anti-Hu
t(8;21)
MCC1 complement deficiency
Anti-MPO antibodies
Hypocretin-1
Anti-voltage-gated Ca2+ channel antibodies
Anti-U1 RNP antibodies
S-100 tumor marker
Cause of liver angiosarcoma
Defect in decay accelerating factor (DAF)
t(11;22)
AFP tumor marker
Auto-antiobdy seen in autoimmune hepatitis
DPC mutation
Gene mutated in NF2
Inheritance of hereditary angioedema
HPV viral protein E7 target
Rosenthal fibers
Anti-Sm antibodies
BCR-ABL fusion gene
CD10 is a positive indicator in...
Anti-Jo-1 antibodies
Analine dyes
Anti-giladin IgA
Gene involved in t(14;18)
Gene mutated in MEN 2a/2b
Anti-tissue transglutiminase IgA
Auto-antiobdy seen in mixed connective tissue disease
HVA in urine
DCC mutation
Auto-antiobdy seen in Churg-Strauss syndrome
c-Myc activating cancer leads to EWSFL1 over-production
AD mutation in APC gene
CA 15-3 tumor marker
Inversion c.16
Auto-antibody seen in microscopic polyangiitis
HintAnswer
AD mutation in p53 gene
Mutated in familial adenomatous polyposis
Auto-antiobdy seen in rheumatoid arthritis
Pseudorosettes with GFAP positive processes
Anti-microsomal antibodies
HPV viral protein E6 target
AD mutation of NF1
Anti-GBM antibodies
t(15;17)
Anti-LKM antibodies
CALLA is a positive indicator in...
BRAF V600E
LDH tumor marker
Receptor targeted by tratuzumab
Anti-ribonucleoprotein antibodies
Deficiency of C1 esterase inhibitor
Auto-antiobdy seen in seen in PBC
Auto-antiobdy seen in drug-induced lupus
What is translocation of mantle cell lymphoma?
Cells that stain (+) for synaptophysin
Homer-wright rosettes
Elevated bombesin
Spindle cells with hair-like glial processes
PML/RARa gene created by
t(8;14)
N-MYC implicated in what cancer
Mutated in Li-Fraumani syndrome
Anti-desmoglein antibodies
Anti-parietal cell antibodies
Anti-SS-A (Ro) antibodies
Cystic brain tumor with granular eosinophilic bodies
Pleomorphic astrocytes with brisk activity and necrosis
AD mutation in MLH1/MSH2
t(11;14)
Cancer of CyclinD dysregulation
Anti-SS-B (La) antibodies
High urinary HVA/VMA + N-Myc
Ki67 fraction >99%
Auto-antiobdy seen in polymyositis

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Created Jan 15, 2014ReportNominate
Tags:disease, gene, marker