Goljan 5 of X: Autoimmune/neoplastic Dz marker

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Can you name the Goljan 5 of X: Disease markers and genes

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ERB-B2 gene
AFP tumor marker
Anti-histone antibodies
Causes centrilobular necrosis and fatty change of the liver
Anti-glutamate decarboxylase antibodies
Auto-antiobdy seen in mixed connective tissue disease
BCR-ABL fusion gene
Anti-intrinsic factor antibodies
Cells that stain (+) for synaptophysin
C-MYC implicated in what cancer
Elevated bombesin
Receptor targeted by tratuzumab
Inheritance of hereditary angioedema
LDH tumor marker
Anti-microsomal antibodies
Cancer of CyclinD dysregulation
Auto-antibody seen in Wegener's granulomatosis
Anti-desmoglein antibodies
Tumor marker for neuroblastoma
CA 19-9 tumor marker
Anti-nuclear antibodies
S-100 tumor marker
Anti-parietal cell antibodies
Gene involved in t(14;18)
CALLA is a positive indicator in...
Elevated tartrate-resistant acid phosphatase
HPV viral protein E6 target
Anti-voltage-gated Ca2+ channel antibodies
NSE, Chromogranin, Synaptophysin, S100 (+)
Anti-insulin antibodies
Mutated in Li-Fraumani syndrome
HPV viral protein E7 target
Anti-giladin IgA
Anti-thyroperoxidase antibodies
N-MYC implicated in what cancer
DPC mutation
c-Myc activating cancer leads to EWSFL1 over-production
What is translocation of mantle cell lymphoma?
Anti-smooth muscle antibodies
DCC mutation
Anti-islet cell antibodies
Pseudorosettes with GFAP positive processes
Mutated in familial adenomatous polyposis
CEA tumor marker
AD mutation of NF1
Auto-antiobdy seen in drug-induced lupus
Anti-ACh receptor antibodies
Gene mutated in NF2
Anti-tissue transglutiminase IgA
PML/RARa gene created by
AD mutation in MLH1/MSH2
Auto-antiobdy seen in polymyositis
AD mutation in APC gene
Cystic brain tumor with granular eosinophilic bodies
Missing enzyme to degrade C3 and C4 convertase on RBCs
HVA in urine
Gene mutated in MEN 2a/2b
Growth factor affected by osteosarcoma
Anti-Jo-1 antibodies
Anti-GBM antibodies
Rosenthal fibers
Anti-LKM antibodies
Complement deficiency + S. pneumo septicemia + lupus-like syndrome
Anti-SS-B (La) antibodies
High urinary HVA/VMA + N-Myc
Anti-Yo, Anti-P|Q, Anti-Hu
Pleomorphic astrocytes with brisk activity and necrosis
Auto-antiobdy seen in CREST syndrome
Anti-DNA topoisomerase 1 antibodies
Deficiency of C1 esterase inhibitor
Ki67 fraction >99%
Auto-antiobdy seen in Goodpasture syndrome
Auto-antibody seen in microscopic polyangiitis
Anti-SCL 70 antibodies
Inversion c.16
Auto-antiobdy seen in Grave's disease
Homer-wright rosettes
Anti-centormere antibodies
Auto-antiobdy seen in Churg-Strauss syndrome
Anti-MPO antibodies
Auto-antiobdy seen in rheumatoid arthritis
Anti-ribonucleoprotein antibodies
MCC1 complement deficiency
CA 125 tumor marker
Anti-mitochondrial antibodies
Anti-SS-A (Ro) antibodies
Thorotrast, arsenic, polyvinyl chloride
Auto-antiobdy seen in seen in PBC
t(8;14) affects what gene
Cause of liver angiosarcoma
Anti-endomysial IgA
Auto-antiobdy seen in autoimmune hepatitis
Anti-IgG antibodies
Gene is involved in t(11;14)
Spindle cells with hair-like glial processes
Analine dyes
Anti-dsDNA antibodies
Anti-proteinase 3 antibodies
AD mutation in p53 gene
Anti-TSH receptor antibodies
CD10 is a positive indicator in...
CA 15-3 tumor marker
Anti-U1 RNP antibodies
Anti-Sm antibodies
Defect in decay accelerating factor (DAF)
Anti-thyroglobulin antibodies

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