Goljan 5 of X: Autoimmune/neoplastic Dz marker

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Can you name the Goljan 5 of X: Disease markers and genes

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Auto-antibody seen in microscopic polyangiitis
Auto-antiobdy seen in mixed connective tissue disease
Analine dyes
CA 125 tumor marker
Defect in decay accelerating factor (DAF)
CA 19-9 tumor marker
Anti-GBM antibodies
Anti-smooth muscle antibodies
Complement deficiency + S. pneumo septicemia + lupus-like syndrome
t(11;22)
Anti-nuclear antibodies
Tumor marker for neuroblastoma
S-100 tumor marker
LDH tumor marker
Anti-voltage-gated Ca2+ channel antibodies
AD mutation in p53 gene
What is translocation of mantle cell lymphoma?
Gene mutated in NF2
C-MYC implicated in what cancer
Anti-insulin antibodies
Auto-antibody seen in Wegener's granulomatosis
CD10 is a positive indicator in...
DCC mutation
Cancer of CyclinD dysregulation
Auto-antiobdy seen in autoimmune hepatitis
Anti-SS-B (La) antibodies
t(8;14)
Pseudorosettes with GFAP positive processes
Anti-Sm antibodies
Anti-SCL 70 antibodies
Anti-endomysial IgA
Auto-antiobdy seen in Goodpasture syndrome
Gene mutated in MEN 2a/2b
Cells that stain (+) for synaptophysin
14-3-3
Auto-antiobdy seen in polymyositis
Thorotrast, arsenic, polyvinyl chloride
High urinary HVA/VMA + N-Myc
Anti-microsomal antibodies
HintAnswer
HVA in urine
Anti-SS-A (Ro) antibodies
BRAF V600E
CEA tumor marker
Anti-desmoglein antibodies
Anti-MPO antibodies
DPC mutation
BCR-ABL fusion gene
Cause of liver angiosarcoma
NSE, Chromogranin, Synaptophysin, S100 (+)
Anti-proteinase 3 antibodies
Receptor targeted by tratuzumab
Anti-U1 RNP antibodies
t(14;18)
t(8;21)
Spindle cells with hair-like glial processes
HPV viral protein E6 target
Anti-islet cell antibodies
PML/RARa gene created by
Hypocretin-1
Elevated tartrate-resistant acid phosphatase
Mutated in Li-Fraumani syndrome
Cystic brain tumor with granular eosinophilic bodies
C-kit
Anti-thyroperoxidase antibodies
Anti-giladin IgA
Gene is involved in t(11;14)
Anti-thyroglobulin antibodies
Auto-antiobdy seen in drug-induced lupus
Elevated bombesin
Inheritance of hereditary angioedema
AD mutation of NF1
MCC1 complement deficiency
Anti-tissue transglutiminase IgA
Anti-parietal cell antibodies
Auto-antiobdy seen in Churg-Strauss syndrome
HPV viral protein E7 target
Anti-dsDNA antibodies
t(9;22)
HintAnswer
ERB-B2 gene
Anti-centormere antibodies
Anti-glutamate decarboxylase antibodies
Mutated in familial adenomatous polyposis
N-MYC implicated in what cancer
Pleomorphic astrocytes with brisk activity and necrosis
t(11;14)
t(8;14) affects what gene
Anti-histone antibodies
t(15;17)
Anti-intrinsic factor antibodies
Anti-ACh receptor antibodies
Causes centrilobular necrosis and fatty change of the liver
Auto-antiobdy seen in Grave's disease
Auto-antiobdy seen in rheumatoid arthritis
Inversion c.16
Homer-wright rosettes
Missing enzyme to degrade C3 and C4 convertase on RBCs
Anti-DNA topoisomerase 1 antibodies
AD mutation in APC gene
AD mutation in MLH1/MSH2
Ki67 fraction >99%
Anti-Yo, Anti-P|Q, Anti-Hu
Gene involved in t(14;18)
Anti-TSH receptor antibodies
Auto-antiobdy seen in seen in PBC
c-Myc activating cancer leads to EWSFL1 over-production
AFP tumor marker
CALLA is a positive indicator in...
Anti-Jo-1 antibodies
Auto-antiobdy seen in CREST syndrome
Anti-LKM antibodies
Anti-mitochondrial antibodies
Rosenthal fibers
CA 15-3 tumor marker
Anti-ribonucleoprotein antibodies
Deficiency of C1 esterase inhibitor
Anti-IgG antibodies
Growth factor affected by osteosarcoma

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Created Jan 15, 2014ReportNominate
Tags:disease, gene, marker