Goljan 5 of X: Autoimmune/neoplastic Dz marker

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Can you name the Goljan 5 of X: Disease markers and genes

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Hypocretin-1
NSE, Chromogranin, Synaptophysin, S100 (+)
Anti-tissue transglutiminase IgA
AD mutation in MLH1/MSH2
BRAF V600E
Auto-antiobdy seen in Grave's disease
Auto-antiobdy seen in polymyositis
Ki67 fraction >99%
Cells that stain (+) for synaptophysin
Auto-antiobdy seen in Goodpasture syndrome
Anti-Jo-1 antibodies
AD mutation of NF1
Anti-histone antibodies
Homer-wright rosettes
Mutated in Li-Fraumani syndrome
Gene involved in t(14;18)
Defect in decay accelerating factor (DAF)
14-3-3
Gene mutated in NF2
Anti-GBM antibodies
ERB-B2 gene
LDH tumor marker
Anti-thyroglobulin antibodies
Anti-centormere antibodies
Cause of liver angiosarcoma
CA 15-3 tumor marker
Auto-antiobdy seen in seen in PBC
Anti-LKM antibodies
AFP tumor marker
Anti-Sm antibodies
t(11;14)
Pseudorosettes with GFAP positive processes
Anti-desmoglein antibodies
CD10 is a positive indicator in...
Receptor targeted by tratuzumab
c-Myc activating cancer leads to EWSFL1 over-production
S-100 tumor marker
Anti-insulin antibodies
Anti-proteinase 3 antibodies
HintAnswer
N-MYC implicated in what cancer
MCC1 complement deficiency
AD mutation in p53 gene
Thorotrast, arsenic, polyvinyl chloride
Anti-thyroperoxidase antibodies
Auto-antiobdy seen in drug-induced lupus
Mutated in familial adenomatous polyposis
Gene mutated in MEN 2a/2b
Gene is involved in t(11;14)
Anti-Yo, Anti-P|Q, Anti-Hu
t(8;14) affects what gene
Inversion c.16
HVA in urine
Anti-giladin IgA
Cancer of CyclinD dysregulation
Analine dyes
DPC mutation
Pleomorphic astrocytes with brisk activity and necrosis
Anti-voltage-gated Ca2+ channel antibodies
Auto-antiobdy seen in CREST syndrome
Anti-smooth muscle antibodies
C-MYC implicated in what cancer
Inheritance of hereditary angioedema
Anti-intrinsic factor antibodies
t(8;14)
Anti-islet cell antibodies
Auto-antiobdy seen in Churg-Strauss syndrome
Anti-DNA topoisomerase 1 antibodies
Cystic brain tumor with granular eosinophilic bodies
High urinary HVA/VMA + N-Myc
Causes centrilobular necrosis and fatty change of the liver
t(15;17)
Anti-IgG antibodies
Anti-nuclear antibodies
C-kit
Anti-parietal cell antibodies
What is translocation of mantle cell lymphoma?
CA 125 tumor marker
t(8;21)
HintAnswer
CALLA is a positive indicator in...
DCC mutation
Complement deficiency + S. pneumo septicemia + lupus-like syndrome
Auto-antiobdy seen in autoimmune hepatitis
Anti-microsomal antibodies
Rosenthal fibers
Auto-antiobdy seen in rheumatoid arthritis
Tumor marker for neuroblastoma
Anti-endomysial IgA
PML/RARa gene created by
Anti-mitochondrial antibodies
CEA tumor marker
Auto-antibody seen in microscopic polyangiitis
t(9;22)
HPV viral protein E6 target
BCR-ABL fusion gene
Missing enzyme to degrade C3 and C4 convertase on RBCs
Anti-U1 RNP antibodies
Auto-antibody seen in Wegener's granulomatosis
Elevated tartrate-resistant acid phosphatase
t(11;22)
t(14;18)
Anti-MPO antibodies
Deficiency of C1 esterase inhibitor
Anti-TSH receptor antibodies
Anti-SS-A (Ro) antibodies
Anti-ribonucleoprotein antibodies
Anti-glutamate decarboxylase antibodies
Elevated bombesin
AD mutation in APC gene
Anti-dsDNA antibodies
CA 19-9 tumor marker
Growth factor affected by osteosarcoma
Anti-SCL 70 antibodies
Anti-SS-B (La) antibodies
Spindle cells with hair-like glial processes
Auto-antiobdy seen in mixed connective tissue disease
HPV viral protein E7 target
Anti-ACh receptor antibodies

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