Goljan 5 of X: Autoimmune/neoplastic Dz marker

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Can you name the Goljan 5 of X: Disease markers and genes

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AD mutation of NF1
PML/RARa gene created by
CALLA is a positive indicator in...
Anti-islet cell antibodies
Anti-glutamate decarboxylase antibodies
Gene mutated in NF2
Anti-endomysial IgA
Anti-GBM antibodies
Anti-nuclear antibodies
Anti-SCL 70 antibodies
Causes centrilobular necrosis and fatty change of the liver
Anti-Jo-1 antibodies
Auto-antiobdy seen in seen in PBC
Receptor targeted by tratuzumab
BCR-ABL fusion gene
t(8;14)
Auto-antiobdy seen in CREST syndrome
AD mutation in MLH1/MSH2
Auto-antiobdy seen in drug-induced lupus
Elevated tartrate-resistant acid phosphatase
Pleomorphic astrocytes with brisk activity and necrosis
Anti-LKM antibodies
S-100 tumor marker
t(8;21)
Gene involved in t(14;18)
Mutated in familial adenomatous polyposis
Analine dyes
Anti-histone antibodies
Anti-U1 RNP antibodies
Auto-antiobdy seen in Grave's disease
Anti-dsDNA antibodies
Inversion c.16
t(8;14) affects what gene
Anti-thyroglobulin antibodies
Auto-antibody seen in microscopic polyangiitis
HPV viral protein E7 target
Anti-voltage-gated Ca2+ channel antibodies
Anti-MPO antibodies
Ki67 fraction >99%
HintAnswer
t(9;22)
AD mutation in p53 gene
t(11;22)
Anti-parietal cell antibodies
Cancer of CyclinD dysregulation
CEA tumor marker
AD mutation in APC gene
CD10 is a positive indicator in...
Cells that stain (+) for synaptophysin
Spindle cells with hair-like glial processes
NSE, Chromogranin, Synaptophysin, S100 (+)
CA 15-3 tumor marker
Thorotrast, arsenic, polyvinyl chloride
C-kit
Defect in decay accelerating factor (DAF)
DPC mutation
14-3-3
Auto-antiobdy seen in Churg-Strauss syndrome
Anti-mitochondrial antibodies
t(14;18)
Anti-thyroperoxidase antibodies
Anti-insulin antibodies
Gene is involved in t(11;14)
Anti-TSH receptor antibodies
What is translocation of mantle cell lymphoma?
Hypocretin-1
Auto-antibody seen in Wegener's granulomatosis
HPV viral protein E6 target
Anti-ACh receptor antibodies
Cause of liver angiosarcoma
AFP tumor marker
Anti-smooth muscle antibodies
Tumor marker for neuroblastoma
Anti-desmoglein antibodies
Auto-antiobdy seen in Goodpasture syndrome
Anti-intrinsic factor antibodies
c-Myc activating cancer leads to EWSFL1 over-production
Homer-wright rosettes
LDH tumor marker
HintAnswer
Anti-IgG antibodies
Anti-giladin IgA
MCC1 complement deficiency
HVA in urine
C-MYC implicated in what cancer
Pseudorosettes with GFAP positive processes
Anti-DNA topoisomerase 1 antibodies
Inheritance of hereditary angioedema
Deficiency of C1 esterase inhibitor
Anti-SS-B (La) antibodies
Anti-tissue transglutiminase IgA
Anti-SS-A (Ro) antibodies
Anti-Sm antibodies
Auto-antiobdy seen in autoimmune hepatitis
Rosenthal fibers
CA 125 tumor marker
ERB-B2 gene
N-MYC implicated in what cancer
CA 19-9 tumor marker
Gene mutated in MEN 2a/2b
Mutated in Li-Fraumani syndrome
Complement deficiency + S. pneumo septicemia + lupus-like syndrome
Anti-Yo, Anti-P|Q, Anti-Hu
Elevated bombesin
Anti-microsomal antibodies
Anti-ribonucleoprotein antibodies
t(15;17)
Missing enzyme to degrade C3 and C4 convertase on RBCs
Cystic brain tumor with granular eosinophilic bodies
DCC mutation
Anti-centormere antibodies
Growth factor affected by osteosarcoma
BRAF V600E
High urinary HVA/VMA + N-Myc
Auto-antiobdy seen in mixed connective tissue disease
Auto-antiobdy seen in rheumatoid arthritis
t(11;14)
Anti-proteinase 3 antibodies
Auto-antiobdy seen in polymyositis

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