Goljan 5 of X: Autoimmune/neoplastic Dz marker

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Can you name the Goljan 5 of X: Disease markers and genes

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CD10 is a positive indicator in...
t(8;14) affects what gene
Auto-antiobdy seen in polymyositis
Anti-thyroglobulin antibodies
Spindle cells with hair-like glial processes
NSE, Chromogranin, Synaptophysin, S100 (+)
Growth factor affected by osteosarcoma
Analine dyes
Tumor marker for neuroblastoma
PML/RARa gene created by
Cystic brain tumor with granular eosinophilic bodies
AD mutation in p53 gene
Gene involved in t(14;18)
Anti-GBM antibodies
Cells that stain (+) for synaptophysin
BRAF V600E
Complement deficiency + S. pneumo septicemia + lupus-like syndrome
Anti-insulin antibodies
Anti-islet cell antibodies
Hypocretin-1
Causes centrilobular necrosis and fatty change of the liver
CALLA is a positive indicator in...
CA 15-3 tumor marker
Inversion c.16
Anti-voltage-gated Ca2+ channel antibodies
Mutated in familial adenomatous polyposis
Auto-antiobdy seen in drug-induced lupus
14-3-3
Auto-antibody seen in microscopic polyangiitis
Auto-antiobdy seen in autoimmune hepatitis
Anti-centormere antibodies
Anti-smooth muscle antibodies
MCC1 complement deficiency
DCC mutation
Pleomorphic astrocytes with brisk activity and necrosis
High urinary HVA/VMA + N-Myc
t(11;22)
LDH tumor marker
Defect in decay accelerating factor (DAF)
HintAnswer
Gene mutated in MEN 2a/2b
Anti-LKM antibodies
Anti-mitochondrial antibodies
BCR-ABL fusion gene
Elevated bombesin
Mutated in Li-Fraumani syndrome
Anti-histone antibodies
Anti-DNA topoisomerase 1 antibodies
Anti-SCL 70 antibodies
HPV viral protein E6 target
Gene is involved in t(11;14)
Anti-ribonucleoprotein antibodies
Auto-antiobdy seen in CREST syndrome
AD mutation of NF1
t(9;22)
Auto-antiobdy seen in rheumatoid arthritis
Anti-MPO antibodies
Auto-antiobdy seen in Churg-Strauss syndrome
Receptor targeted by tratuzumab
c-Myc activating cancer leads to EWSFL1 over-production
Deficiency of C1 esterase inhibitor
Auto-antibody seen in Wegener's granulomatosis
DPC mutation
Anti-TSH receptor antibodies
Ki67 fraction >99%
t(14;18)
Anti-parietal cell antibodies
Gene mutated in NF2
AD mutation in MLH1/MSH2
AFP tumor marker
Anti-intrinsic factor antibodies
Anti-U1 RNP antibodies
CA 125 tumor marker
Cancer of CyclinD dysregulation
AD mutation in APC gene
HPV viral protein E7 target
t(15;17)
Anti-IgG antibodies
Anti-Sm antibodies
HintAnswer
Anti-microsomal antibodies
Anti-endomysial IgA
Cause of liver angiosarcoma
t(11;14)
Anti-giladin IgA
Anti-Yo, Anti-P|Q, Anti-Hu
ERB-B2 gene
t(8;14)
Elevated tartrate-resistant acid phosphatase
S-100 tumor marker
C-kit
Inheritance of hereditary angioedema
Auto-antiobdy seen in Goodpasture syndrome
Missing enzyme to degrade C3 and C4 convertase on RBCs
t(8;21)
Anti-nuclear antibodies
What is translocation of mantle cell lymphoma?
Anti-desmoglein antibodies
Anti-proteinase 3 antibodies
Anti-ACh receptor antibodies
Auto-antiobdy seen in mixed connective tissue disease
CEA tumor marker
Anti-SS-A (Ro) antibodies
N-MYC implicated in what cancer
Anti-glutamate decarboxylase antibodies
Anti-SS-B (La) antibodies
Auto-antiobdy seen in Grave's disease
C-MYC implicated in what cancer
CA 19-9 tumor marker
Anti-Jo-1 antibodies
HVA in urine
Anti-tissue transglutiminase IgA
Pseudorosettes with GFAP positive processes
Thorotrast, arsenic, polyvinyl chloride
Anti-dsDNA antibodies
Auto-antiobdy seen in seen in PBC
Rosenthal fibers
Homer-wright rosettes
Anti-thyroperoxidase antibodies

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Created Jan 15, 2014ReportNominate
Tags:disease, gene, marker