Goljan 5 of X: Autoimmune/neoplastic Dz marker

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Can you name the Goljan 5 of X: Disease markers and genes

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Deficiency of C1 esterase inhibitor
Auto-antiobdy seen in Churg-Strauss syndrome
Missing enzyme to degrade C3 and C4 convertase on RBCs
Anti-proteinase 3 antibodies
Anti-IgG antibodies
BRAF V600E
Anti-U1 RNP antibodies
Ki67 fraction >99%
Auto-antiobdy seen in autoimmune hepatitis
HVA in urine
Causes centrilobular necrosis and fatty change of the liver
ERB-B2 gene
Pleomorphic astrocytes with brisk activity and necrosis
BCR-ABL fusion gene
AD mutation of NF1
t(8;14) affects what gene
Gene mutated in NF2
HPV viral protein E6 target
NSE, Chromogranin, Synaptophysin, S100 (+)
CA 19-9 tumor marker
Anti-SS-A (Ro) antibodies
CA 125 tumor marker
c-Myc activating cancer leads to EWSFL1 over-production
Anti-TSH receptor antibodies
Cancer of CyclinD dysregulation
Anti-parietal cell antibodies
Anti-voltage-gated Ca2+ channel antibodies
HPV viral protein E7 target
Anti-giladin IgA
Inheritance of hereditary angioedema
What is translocation of mantle cell lymphoma?
Anti-DNA topoisomerase 1 antibodies
Tumor marker for neuroblastoma
Auto-antiobdy seen in mixed connective tissue disease
Cause of liver angiosarcoma
Auto-antibody seen in Wegener's granulomatosis
Anti-nuclear antibodies
t(11;22)
t(14;18)
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Pseudorosettes with GFAP positive processes
Anti-LKM antibodies
Anti-MPO antibodies
Anti-insulin antibodies
Anti-ACh receptor antibodies
Elevated bombesin
DCC mutation
C-kit
Rosenthal fibers
Anti-SS-B (La) antibodies
AD mutation in p53 gene
Auto-antiobdy seen in Goodpasture syndrome
Growth factor affected by osteosarcoma
CD10 is a positive indicator in...
Spindle cells with hair-like glial processes
CEA tumor marker
t(9;22)
t(8;21)
C-MYC implicated in what cancer
Gene is involved in t(11;14)
LDH tumor marker
Anti-desmoglein antibodies
Anti-tissue transglutiminase IgA
Mutated in Li-Fraumani syndrome
CALLA is a positive indicator in...
Anti-Sm antibodies
AD mutation in MLH1/MSH2
Mutated in familial adenomatous polyposis
t(8;14)
Elevated tartrate-resistant acid phosphatase
Complement deficiency + S. pneumo septicemia + lupus-like syndrome
Gene involved in t(14;18)
Auto-antiobdy seen in rheumatoid arthritis
Anti-thyroperoxidase antibodies
N-MYC implicated in what cancer
Anti-intrinsic factor antibodies
AD mutation in APC gene
Receptor targeted by tratuzumab
S-100 tumor marker
HintAnswer
Thorotrast, arsenic, polyvinyl chloride
MCC1 complement deficiency
Anti-ribonucleoprotein antibodies
PML/RARa gene created by
t(15;17)
t(11;14)
Anti-Yo, Anti-P|Q, Anti-Hu
Auto-antibody seen in microscopic polyangiitis
Anti-centormere antibodies
AFP tumor marker
Anti-endomysial IgA
Cells that stain (+) for synaptophysin
Inversion c.16
Anti-SCL 70 antibodies
Analine dyes
Hypocretin-1
Auto-antiobdy seen in drug-induced lupus
Cystic brain tumor with granular eosinophilic bodies
14-3-3
Anti-islet cell antibodies
Auto-antiobdy seen in CREST syndrome
Anti-GBM antibodies
Anti-glutamate decarboxylase antibodies
High urinary HVA/VMA + N-Myc
Auto-antiobdy seen in Grave's disease
Gene mutated in MEN 2a/2b
Anti-microsomal antibodies
Anti-mitochondrial antibodies
Anti-thyroglobulin antibodies
Anti-Jo-1 antibodies
CA 15-3 tumor marker
Anti-histone antibodies
DPC mutation
Anti-smooth muscle antibodies
Defect in decay accelerating factor (DAF)
Auto-antiobdy seen in polymyositis
Homer-wright rosettes
Anti-dsDNA antibodies
Auto-antiobdy seen in seen in PBC

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Created Jan 15, 2014ReportNominate
Tags:disease, gene, marker