Goljan 5 of X: Autoimmune/neoplastic Dz marker

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Can you name the Goljan 5 of X: Disease markers and genes

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CEA tumor marker
Anti-GBM antibodies
Anti-endomysial IgA
Inversion c.16
Causes centrilobular necrosis and fatty change of the liver
Auto-antiobdy seen in CREST syndrome
Anti-nuclear antibodies
Anti-SS-A (Ro) antibodies
Anti-proteinase 3 antibodies
Anti-LKM antibodies
DCC mutation
AD mutation in MLH1/MSH2
Auto-antiobdy seen in seen in PBC
Anti-glutamate decarboxylase antibodies
CA 19-9 tumor marker
AD mutation of NF1
Cystic brain tumor with granular eosinophilic bodies
Pseudorosettes with GFAP positive processes
Anti-TSH receptor antibodies
Auto-antiobdy seen in mixed connective tissue disease
Anti-microsomal antibodies
NSE, Chromogranin, Synaptophysin, S100 (+)
Anti-voltage-gated Ca2+ channel antibodies
Spindle cells with hair-like glial processes
Auto-antiobdy seen in polymyositis
CA 125 tumor marker
Anti-mitochondrial antibodies
What is translocation of mantle cell lymphoma?
HVA in urine
Deficiency of C1 esterase inhibitor
Mutated in Li-Fraumani syndrome
ERB-B2 gene
Anti-dsDNA antibodies
AD mutation in APC gene
Defect in decay accelerating factor (DAF)
Anti-Sm antibodies
t(8;14) affects what gene
AFP tumor marker
Auto-antiobdy seen in rheumatoid arthritis
Anti-parietal cell antibodies
Auto-antibody seen in microscopic polyangiitis
Gene mutated in MEN 2a/2b
S-100 tumor marker
Anti-MPO antibodies
Anti-thyroperoxidase antibodies
AD mutation in p53 gene
Anti-histone antibodies
Ki67 fraction >99%
Anti-islet cell antibodies
Cells that stain (+) for synaptophysin
Auto-antiobdy seen in Grave's disease
Pleomorphic astrocytes with brisk activity and necrosis
Anti-ACh receptor antibodies
Homer-wright rosettes
DPC mutation
Elevated tartrate-resistant acid phosphatase
Anti-Jo-1 antibodies
Complement deficiency + S. pneumo septicemia + lupus-like syndrome
Growth factor affected by osteosarcoma
Anti-centormere antibodies
High urinary HVA/VMA + N-Myc
Anti-DNA topoisomerase 1 antibodies
HPV viral protein E7 target
Anti-SCL 70 antibodies
Elevated bombesin
Auto-antiobdy seen in drug-induced lupus
Gene involved in t(14;18)
Mutated in familial adenomatous polyposis
Auto-antibody seen in Wegener's granulomatosis
Anti-ribonucleoprotein antibodies
Gene is involved in t(11;14)
Anti-Yo, Anti-P|Q, Anti-Hu
c-Myc activating cancer leads to EWSFL1 over-production
CD10 is a positive indicator in...
Anti-smooth muscle antibodies
MCC1 complement deficiency
BCR-ABL fusion gene
Anti-SS-B (La) antibodies
CALLA is a positive indicator in...
LDH tumor marker
Inheritance of hereditary angioedema
Cancer of CyclinD dysregulation
Anti-desmoglein antibodies
Missing enzyme to degrade C3 and C4 convertase on RBCs
Receptor targeted by tratuzumab
Gene mutated in NF2
PML/RARa gene created by
Cause of liver angiosarcoma
Anti-thyroglobulin antibodies
HPV viral protein E6 target
Anti-giladin IgA
Rosenthal fibers
Tumor marker for neuroblastoma
Anti-tissue transglutiminase IgA
Thorotrast, arsenic, polyvinyl chloride
Anti-insulin antibodies
Analine dyes
Anti-intrinsic factor antibodies
CA 15-3 tumor marker
Anti-U1 RNP antibodies
Auto-antiobdy seen in Churg-Strauss syndrome
Auto-antiobdy seen in Goodpasture syndrome
Auto-antiobdy seen in autoimmune hepatitis
N-MYC implicated in what cancer
Anti-IgG antibodies
C-MYC implicated in what cancer

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