Goljan 5 of X: Autoimmune/neoplastic Dz marker

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Can you name the Goljan 5 of X: Disease markers and genes

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Anti-Sm antibodies
DCC mutation
Anti-parietal cell antibodies
Auto-antiobdy seen in polymyositis
Thorotrast, arsenic, polyvinyl chloride
c-Myc activating cancer leads to EWSFL1 over-production
Anti-SS-B (La) antibodies
Anti-desmoglein antibodies
Anti-proteinase 3 antibodies
Auto-antiobdy seen in mixed connective tissue disease
Gene mutated in MEN 2a/2b
High urinary HVA/VMA + N-Myc
Defect in decay accelerating factor (DAF)
Anti-centormere antibodies
Receptor targeted by tratuzumab
Ki67 fraction >99%
CA 19-9 tumor marker
Anti-glutamate decarboxylase antibodies
AFP tumor marker
Deficiency of C1 esterase inhibitor
N-MYC implicated in what cancer
Anti-DNA topoisomerase 1 antibodies
Gene mutated in NF2
Analine dyes
Anti-nuclear antibodies
Anti-IgG antibodies
Inversion c.16
Anti-voltage-gated Ca2+ channel antibodies
Anti-islet cell antibodies
Elevated bombesin
Gene involved in t(14;18)
C-MYC implicated in what cancer
MCC1 complement deficiency
AD mutation in p53 gene
Anti-TSH receptor antibodies
Anti-mitochondrial antibodies
Cause of liver angiosarcoma
Anti-giladin IgA
Gene is involved in t(11;14)
Anti-ACh receptor antibodies
AD mutation of NF1
S-100 tumor marker
Missing enzyme to degrade C3 and C4 convertase on RBCs
Complement deficiency + S. pneumo septicemia + lupus-like syndrome
Tumor marker for neuroblastoma
BCR-ABL fusion gene
CEA tumor marker
Cystic brain tumor with granular eosinophilic bodies
Auto-antibody seen in microscopic polyangiitis
Anti-histone antibodies
LDH tumor marker
Causes centrilobular necrosis and fatty change of the liver
t(8;14) affects what gene
Auto-antiobdy seen in rheumatoid arthritis
Anti-tissue transglutiminase IgA
Anti-intrinsic factor antibodies
Auto-antiobdy seen in CREST syndrome
ERB-B2 gene
Anti-endomysial IgA
Auto-antiobdy seen in Goodpasture syndrome
Pseudorosettes with GFAP positive processes
Anti-dsDNA antibodies
Anti-MPO antibodies
CA 125 tumor marker
Auto-antiobdy seen in drug-induced lupus
CD10 is a positive indicator in...
Mutated in familial adenomatous polyposis
Anti-LKM antibodies
Mutated in Li-Fraumani syndrome
Cells that stain (+) for synaptophysin
Homer-wright rosettes
Auto-antiobdy seen in Churg-Strauss syndrome
Auto-antiobdy seen in autoimmune hepatitis
Anti-SS-A (Ro) antibodies
Auto-antiobdy seen in seen in PBC
Growth factor affected by osteosarcoma
Anti-Jo-1 antibodies
Spindle cells with hair-like glial processes
Anti-thyroglobulin antibodies
DPC mutation
PML/RARa gene created by
Anti-GBM antibodies
Rosenthal fibers
What is translocation of mantle cell lymphoma?
AD mutation in APC gene
Anti-smooth muscle antibodies
HVA in urine
Anti-microsomal antibodies
Anti-SCL 70 antibodies
HPV viral protein E6 target
Cancer of CyclinD dysregulation
AD mutation in MLH1/MSH2
Anti-Yo, Anti-P|Q, Anti-Hu
Auto-antibody seen in Wegener's granulomatosis
Anti-insulin antibodies
Anti-ribonucleoprotein antibodies
Anti-thyroperoxidase antibodies
NSE, Chromogranin, Synaptophysin, S100 (+)
Anti-U1 RNP antibodies
Elevated tartrate-resistant acid phosphatase
Auto-antiobdy seen in Grave's disease
CALLA is a positive indicator in...
HPV viral protein E7 target
CA 15-3 tumor marker
Inheritance of hereditary angioedema
Pleomorphic astrocytes with brisk activity and necrosis

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