Goljan 5 of X: Autoimmune/neoplastic Dz marker

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Can you name the Goljan 5 of X: Disease markers and genes

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Anti-parietal cell antibodies
HPV viral protein E7 target
Anti-Yo, Anti-P|Q, Anti-Hu
Mutated in familial adenomatous polyposis
AD mutation in MLH1/MSH2
Anti-desmoglein antibodies
AD mutation in p53 gene
Anti-ribonucleoprotein antibodies
Anti-GBM antibodies
AFP tumor marker
Missing enzyme to degrade C3 and C4 convertase on RBCs
Receptor targeted by tratuzumab
LDH tumor marker
Anti-dsDNA antibodies
C-MYC implicated in what cancer
Anti-histone antibodies
Cells that stain (+) for synaptophysin
CA 15-3 tumor marker
C-kit
Anti-thyroperoxidase antibodies
DPC mutation
14-3-3
MCC1 complement deficiency
Auto-antiobdy seen in autoimmune hepatitis
Anti-islet cell antibodies
Anti-IgG antibodies
CD10 is a positive indicator in...
Cause of liver angiosarcoma
Inheritance of hereditary angioedema
t(11;22)
Anti-DNA topoisomerase 1 antibodies
BCR-ABL fusion gene
Rosenthal fibers
Anti-proteinase 3 antibodies
Auto-antibody seen in Wegener's granulomatosis
Auto-antiobdy seen in CREST syndrome
CA 19-9 tumor marker
t(14;18)
Auto-antiobdy seen in drug-induced lupus
HintAnswer
NSE, Chromogranin, Synaptophysin, S100 (+)
Gene mutated in NF2
Anti-U1 RNP antibodies
PML/RARa gene created by
CALLA is a positive indicator in...
BRAF V600E
HVA in urine
t(8;21)
Auto-antibody seen in microscopic polyangiitis
Anti-voltage-gated Ca2+ channel antibodies
High urinary HVA/VMA + N-Myc
Auto-antiobdy seen in seen in PBC
Ki67 fraction >99%
Pleomorphic astrocytes with brisk activity and necrosis
Anti-Sm antibodies
Anti-giladin IgA
Deficiency of C1 esterase inhibitor
Anti-thyroglobulin antibodies
CA 125 tumor marker
Auto-antiobdy seen in rheumatoid arthritis
Anti-SS-A (Ro) antibodies
Inversion c.16
Anti-mitochondrial antibodies
Pseudorosettes with GFAP positive processes
AD mutation of NF1
Elevated tartrate-resistant acid phosphatase
Anti-microsomal antibodies
Anti-endomysial IgA
Thorotrast, arsenic, polyvinyl chloride
Anti-Jo-1 antibodies
Anti-tissue transglutiminase IgA
Hypocretin-1
Anti-TSH receptor antibodies
Spindle cells with hair-like glial processes
Causes centrilobular necrosis and fatty change of the liver
Anti-nuclear antibodies
Complement deficiency + S. pneumo septicemia + lupus-like syndrome
Anti-intrinsic factor antibodies
Auto-antiobdy seen in Churg-Strauss syndrome
HintAnswer
Gene mutated in MEN 2a/2b
Anti-SCL 70 antibodies
Auto-antiobdy seen in Grave's disease
Defect in decay accelerating factor (DAF)
Auto-antiobdy seen in mixed connective tissue disease
Anti-ACh receptor antibodies
Analine dyes
HPV viral protein E6 target
Anti-MPO antibodies
Anti-centormere antibodies
Anti-LKM antibodies
Anti-glutamate decarboxylase antibodies
t(15;17)
t(8;14)
t(8;14) affects what gene
Homer-wright rosettes
Auto-antiobdy seen in Goodpasture syndrome
Mutated in Li-Fraumani syndrome
Growth factor affected by osteosarcoma
t(11;14)
Gene is involved in t(11;14)
Anti-SS-B (La) antibodies
Tumor marker for neuroblastoma
Auto-antiobdy seen in polymyositis
Anti-insulin antibodies
N-MYC implicated in what cancer
ERB-B2 gene
What is translocation of mantle cell lymphoma?
CEA tumor marker
Gene involved in t(14;18)
Cancer of CyclinD dysregulation
Anti-smooth muscle antibodies
Elevated bombesin
t(9;22)
S-100 tumor marker
c-Myc activating cancer leads to EWSFL1 over-production
DCC mutation
Cystic brain tumor with granular eosinophilic bodies
AD mutation in APC gene

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Created Jan 15, 2014ReportNominate
Tags:disease, gene, marker