Goljan 5 of X: Autoimmune/neoplastic Dz marker

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Can you name the Goljan 5 of X: Disease markers and genes

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PML/RARa gene created by
Inheritance of hereditary angioedema
Anti-U1 RNP antibodies
Gene mutated in NF2
Mutated in Li-Fraumani syndrome
Tumor marker for neuroblastoma
Anti-TSH receptor antibodies
N-MYC implicated in what cancer
Elevated tartrate-resistant acid phosphatase
Cause of liver angiosarcoma
DCC mutation
Anti-thyroperoxidase antibodies
Elevated bombesin
Anti-Sm antibodies
BCR-ABL fusion gene
Anti-Yo, Anti-P|Q, Anti-Hu
CALLA is a positive indicator in...
Anti-glutamate decarboxylase antibodies
Anti-ribonucleoprotein antibodies
c-Myc activating cancer leads to EWSFL1 over-production
Anti-tissue transglutiminase IgA
What is translocation of mantle cell lymphoma?
CD10 is a positive indicator in...
DPC mutation
Anti-intrinsic factor antibodies
Anti-parietal cell antibodies
Anti-voltage-gated Ca2+ channel antibodies
ERB-B2 gene
t(11;22)
Auto-antiobdy seen in rheumatoid arthritis
Anti-SS-B (La) antibodies
AFP tumor marker
Anti-SCL 70 antibodies
CA 15-3 tumor marker
Mutated in familial adenomatous polyposis
Anti-GBM antibodies
CA 125 tumor marker
High urinary HVA/VMA + N-Myc
HPV viral protein E7 target
HintAnswer
Anti-histone antibodies
Hypocretin-1
Anti-proteinase 3 antibodies
14-3-3
Receptor targeted by tratuzumab
CA 19-9 tumor marker
t(11;14)
Auto-antibody seen in microscopic polyangiitis
MCC1 complement deficiency
t(9;22)
LDH tumor marker
AD mutation in APC gene
Defect in decay accelerating factor (DAF)
Anti-islet cell antibodies
Homer-wright rosettes
Anti-desmoglein antibodies
Anti-thyroglobulin antibodies
Gene involved in t(14;18)
Anti-SS-A (Ro) antibodies
BRAF V600E
Auto-antiobdy seen in Grave's disease
Growth factor affected by osteosarcoma
Auto-antiobdy seen in polymyositis
Anti-ACh receptor antibodies
Deficiency of C1 esterase inhibitor
Anti-insulin antibodies
Anti-nuclear antibodies
Anti-centormere antibodies
Anti-smooth muscle antibodies
Auto-antiobdy seen in autoimmune hepatitis
NSE, Chromogranin, Synaptophysin, S100 (+)
Anti-mitochondrial antibodies
Cells that stain (+) for synaptophysin
Spindle cells with hair-like glial processes
Causes centrilobular necrosis and fatty change of the liver
C-MYC implicated in what cancer
CEA tumor marker
Anti-dsDNA antibodies
Anti-Jo-1 antibodies
HintAnswer
HVA in urine
t(8;21)
Pleomorphic astrocytes with brisk activity and necrosis
Anti-endomysial IgA
Auto-antiobdy seen in mixed connective tissue disease
S-100 tumor marker
Anti-giladin IgA
Anti-IgG antibodies
Missing enzyme to degrade C3 and C4 convertase on RBCs
C-kit
Gene is involved in t(11;14)
t(14;18)
Rosenthal fibers
Analine dyes
AD mutation in MLH1/MSH2
AD mutation of NF1
t(15;17)
HPV viral protein E6 target
Inversion c.16
Complement deficiency + S. pneumo septicemia + lupus-like syndrome
Thorotrast, arsenic, polyvinyl chloride
Anti-microsomal antibodies
Gene mutated in MEN 2a/2b
Auto-antiobdy seen in seen in PBC
t(8;14)
Cancer of CyclinD dysregulation
Cystic brain tumor with granular eosinophilic bodies
Ki67 fraction >99%
t(8;14) affects what gene
AD mutation in p53 gene
Anti-MPO antibodies
Anti-DNA topoisomerase 1 antibodies
Auto-antiobdy seen in Churg-Strauss syndrome
Auto-antiobdy seen in drug-induced lupus
Pseudorosettes with GFAP positive processes
Anti-LKM antibodies
Auto-antibody seen in Wegener's granulomatosis
Auto-antiobdy seen in CREST syndrome
Auto-antiobdy seen in Goodpasture syndrome

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