low potency typical antipsychotic

Name the class: side effects = extrapyramidal signs, tardive dyskinesia, hyperprolactinemia, anticholinergic sx

high potency typical antipsychotic

atypical antipsychotic causing agranulocytosis, significant weight gain and cardiometabolic risk, seizures, salivation, sedation, myocarditis

atypical antipsychotic causing sedation, weight gain, significant cardiometabolic risk

atypical antipsychotic preferentially used in PD patients with no prolactinemia or EPS, and more NE activity leading to antidepressant effect. weight gain at high doses

typical antipsychotic mechanism of action

atypical antipsychotic mechanism of action

atypical antipsychotic causing significant weight gain & cardiometabolic risk, low EPS, increased QT interval. next generation rispiridone

atypical antipsychotic with moderate weight gain and cardiometabolic risk, EPS and prolactinemia in high doses, can be used in pediatrics or as a two week depot injection

atypical antipsychotic causing significant QTc prolongation; EPS; prolactinemia; low weight gain and cardiometabolic risk

atypical antipsychotic with lowest weight gain and cardiometabolic risk, low sedation; agitation, akathesia

mood stabilizer for both manic & depressive phases

mood stabilizer causing tremor, nausea, diarrhea, diabetes insipidus, hypothyroidism, weight gain, alopeicia, fetal heart defects

mood stabilizer excreted 100% through kidney, with sodium; don't take w/ NSAIDs!

anticonvultant/mood stabilizer used for Bipolar 1 mania & rapid cycling; causes sedation, weight gain, tremor, alopecia, PCOS, thrombocytopenia, hepatotoxicity, neural tube defects

anticonvulsant/mood stabilizer used off-label for depressive phase of bipolar 1; causes sedation, stevens-johnson in 1/1000, hepatic metabolism

anticonvulsant/mood stabilizer used to treat manic phase of bipolar 1; causes sedation, stevens-johnson, agranulocytosis, ataxia, SIADH, elevated liver enzymes, neural tube defects

anticonvulsant/mood stabilizer used off-label for mania in bipolar 1; few side effects except sedation and risk of SIADH; hepatic metabolism

drug class with side effects of anxiety, restlessness, sleep disturbance, nausea, headache, tremor, perspiration, dry mouth, sexual dysfunction

SSRI with the longest half life

SSRI with weak dopaminergic activity; may be useful after a brain injury

SSRI with the fewest drug interactions

SSRI used for OCD

weird antidepressant that decreases sexual side effects if co-administered w/ SSRIs, but may cause electrolyte imbalance that increases seizure risk

serotonin pre-synaptic reuptake inhibitor. sedation but few sexual side effects; rare hepatic failure

SNRI for depression and anxiety. similar SEs to SSRIs plus dose-dependent increase in BP; few drug interactions

SNRI for depression and fibromyalgia; more NE effect & more stable blood levels than venlafaxine

SNRI for depression, anxiety, and pain disorders; much less likely than venlafaxine to cause dose-dependent HTN

alpha-2 adrenergic receptor antagonist used for depression & anxiety, causes sedation, weight gain, and rare agranulocytosis

NE inhibitor used for insomnia and rarely depression, can cause priapism (too much of a good thing?)

5-HT1a partial agonist used as an anxiolytic; can cause dizziness

drug class that potentiates GABA receptor via BZD receptor; can cause sedation, confusion; dangerous w/ EtOH (respiratory depression), used as anxiolytics

drug class that binds GABA-mediated chloride channel; sedatives used to treat epilepsy, induce P450, dangerous in overdose, can cause incoordination, CNS suppression, drug interact

the three benzos that don't require oxidation--ok to use in pts w/ liver failure

selective BZD receptor agonists used for insomnia

atomoxetine (Straterra) mechanism

non-stimulant ADHD drug with side effects of appetite decrease, GI symptoms, mild increase in pulse and BP, rare and serious hepatotoxicity; no abuse potential; must be taken daily

adhd drug class structually similar to endogenous catecholamines; have DA and NE neurotransmission properties; improve but may not normalize cognitive performance

once daily adhd stimulant drugs

twice daily adhd stimulant drugs

thrice daily adhd stimulant drug

drug class that can cause appetite suppression, sleep and mood disturbancces, irritability and anxiety, headaches, tics

drug class causing anticholinergic symptoms (dry mouth, urinary retention, constipation, blurred vision); alpha adrenergic blockade (orthostatic hypotension), and antihistamine eff

safest treatment for bipolar and major depression during pregnancy

SSRI w/ 2D6 inhibition & sedation; useful for anxiety disorders (also depression)

NMDA antagonist used for dementia

Acetylcholinesterase inhibitorsused for dementia