Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
Leukemias, thyroid, bone cancersenvironmental/occupational
Wilm's Tumorgene mutation, in kids
Gastric cancerbacteria
Cervical CancerHPV types
Li-Fraumeni Syndromegene mutation
Follicular Lymphomat(14;18)
Cervical CancerHPV genes
Kaposi's Sarcoma (in AIDS)virus
Familial polyposis coligene mutation
T Cell neoplasmsGene overexpression
Some immunodeficiency statesgene mutation
Mantle Cell lymphomat(11;14), overexpress cyclin
Lung and Skin cancersenvironmental
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
T Cell leukemiavirus
Nasopharyngeal Cancersvirus
Transcriptional Activationgeneral oncogene
Cancer CausedGenes/EffectorsHints
Familial melanomaGene mutation
Neurofibromatosis Type 1gene mutation
Renal cancergene mutation, in adults
Hepatocellular carcinomaenvironmental
Burkitt Lymphomavirus
Hepatocellular CarcinomaResult of HBV liver damage
Hereditary nonpolyposis colon cancermismatch DNA repair
Xeroderma Pigmentosum (skin cancer)general category of DNA repair
Sporadic Breast Cancergene overexpression
Retinoblastomagene mutation
Acute Leukemiaenvironmental
Some leukemias and lymphomasinherited syndrome
Liver cancertoxin from Aspergillus
Liver angiosarcomaenvironmental
Familial Breast Cancer, OvarianGene mutation

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