Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
Nasopharyngeal Cancersvirus
Hepatocellular carcinomaenvironmental
Gastric cancerbacteria
Mantle Cell lymphomat(11;14), overexpress cyclin
Hepatocellular CarcinomaResult of HBV liver damage
Renal cancergene mutation, in adults
Follicular Lymphomat(14;18)
Cervical CancerHPV genes
Li-Fraumeni Syndromegene mutation
Burkitt Lymphomavirus
Cervical CancerHPV types
Leukemias, thyroid, bone cancersenvironmental/occupational
Some leukemias and lymphomasinherited syndrome
Familial melanomaGene mutation
Transcriptional Activationgeneral oncogene
T Cell leukemiavirus
Cancer CausedGenes/EffectorsHints
Xeroderma Pigmentosum (skin cancer)general category of DNA repair
Lung and Skin cancersenvironmental
Acute Leukemiaenvironmental
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
Liver cancertoxin from Aspergillus
Familial Breast Cancer, OvarianGene mutation
Sporadic Breast Cancergene overexpression
Familial polyposis coligene mutation
Wilm's Tumorgene mutation, in kids
Retinoblastomagene mutation
Some immunodeficiency statesgene mutation
Liver angiosarcomaenvironmental
Neurofibromatosis Type 1gene mutation
Hereditary nonpolyposis colon cancermismatch DNA repair
T Cell neoplasmsGene overexpression
Kaposi's Sarcoma (in AIDS)virus

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