Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
Leukemias, thyroid, bone cancersenvironmental/occupational
Lung and Skin cancersenvironmental
Cervical CancerHPV genes
Familial melanomaGene mutation
Neurofibromatosis Type 1gene mutation
Li-Fraumeni Syndromegene mutation
Liver cancertoxin from Aspergillus
Familial polyposis coligene mutation
Hereditary nonpolyposis colon cancermismatch DNA repair
Mesotheliomaenvironmental
Some leukemias and lymphomasinherited syndrome
Mantle Cell lymphomat(11;14), overexpress cyclin
T Cell leukemiavirus
Xeroderma Pigmentosum (skin cancer)general category of DNA repair
Burkitt Lymphomavirus
Follicular Lymphomat(14;18)
Transcriptional Activationgeneral oncogene
Cancer CausedGenes/EffectorsHints
Nasopharyngeal Cancersvirus
Wilm's Tumorgene mutation, in kids
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
Retinoblastomagene mutation
Gastric cancerbacteria
Some immunodeficiency statesgene mutation
Hepatocellular carcinomaenvironmental
Acute Leukemiaenvironmental
Kaposi's Sarcoma (in AIDS)virus
Liver angiosarcomaenvironmental
T Cell neoplasmsGene overexpression
Hepatocellular CarcinomaResult of HBV liver damage
Renal cancergene mutation, in adults
Sporadic Breast Cancergene overexpression
Familial Breast Cancer, OvarianGene mutation
Cervical CancerHPV types

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Created Feb 26, 2011SourceReportNominate
Tags:cancer