Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
Mantle Cell lymphomat(11;14), overexpress cyclin
Some leukemias and lymphomasinherited syndrome
T Cell leukemiavirus
Retinoblastomagene mutation
T Cell neoplasmsGene overexpression
Follicular Lymphomat(14;18)
Hepatocellular carcinomaenvironmental
Some immunodeficiency statesgene mutation
Familial Breast Cancer, OvarianGene mutation
Liver cancertoxin from Aspergillus
Leukemias, thyroid, bone cancersenvironmental/occupational
Burkitt Lymphomavirus
Cervical CancerHPV types
Wilm's Tumorgene mutation, in kids
Lung and Skin cancersenvironmental
Familial melanomaGene mutation
Cancer CausedGenes/EffectorsHints
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
Liver angiosarcomaenvironmental
Nasopharyngeal Cancersvirus
Cervical CancerHPV genes
Sporadic Breast Cancergene overexpression
Xeroderma Pigmentosum (skin cancer)general category of DNA repair
Gastric cancerbacteria
Transcriptional Activationgeneral oncogene
Renal cancergene mutation, in adults
Acute Leukemiaenvironmental
Kaposi's Sarcoma (in AIDS)virus
Li-Fraumeni Syndromegene mutation
Hepatocellular CarcinomaResult of HBV liver damage
Familial polyposis coligene mutation
Hereditary nonpolyposis colon cancermismatch DNA repair
Neurofibromatosis Type 1gene mutation

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Created Feb 26, 2011SourceReportNominate