Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
Familial polyposis coligene mutation
Xeroderma Pigmentosum (skin cancer)general category of DNA repair
T Cell leukemiavirus
Lung and Skin cancersenvironmental
Cervical CancerHPV genes
Burkitt Lymphomavirus
Hepatocellular CarcinomaResult of HBV liver damage
Acute Leukemiaenvironmental
Mantle Cell lymphomat(11;14), overexpress cyclin
Cervical CancerHPV types
Wilm's Tumorgene mutation, in kids
Neurofibromatosis Type 1gene mutation
Li-Fraumeni Syndromegene mutation
Familial Breast Cancer, OvarianGene mutation
Hereditary nonpolyposis colon cancermismatch DNA repair
Some leukemias and lymphomasinherited syndrome
Nasopharyngeal Cancersvirus
Cancer CausedGenes/EffectorsHints
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
Liver cancertoxin from Aspergillus
Retinoblastomagene mutation
Sporadic Breast Cancergene overexpression
Renal cancergene mutation, in adults
Transcriptional Activationgeneral oncogene
Kaposi's Sarcoma (in AIDS)virus
Gastric cancerbacteria
Some immunodeficiency statesgene mutation
Leukemias, thyroid, bone cancersenvironmental/occupational
Hepatocellular carcinomaenvironmental
T Cell neoplasmsGene overexpression
Familial melanomaGene mutation
Mesotheliomaenvironmental
Liver angiosarcomaenvironmental
Follicular Lymphomat(14;18)

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