Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
Wilm's Tumorgene mutation, in kids
Hepatocellular CarcinomaResult of HBV liver damage
Acute Leukemiaenvironmental
Burkitt Lymphomavirus
Some leukemias and lymphomasinherited syndrome
Liver angiosarcomaenvironmental
Nasopharyngeal Cancersvirus
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
Sporadic Breast Cancergene overexpression
Mantle Cell lymphomat(11;14), overexpress cyclin
Familial Breast Cancer, OvarianGene mutation
Li-Fraumeni Syndromegene mutation
Neurofibromatosis Type 1gene mutation
Renal cancergene mutation, in adults
T Cell leukemiavirus
Follicular Lymphomat(14;18)
Cancer CausedGenes/EffectorsHints
Leukemias, thyroid, bone cancersenvironmental/occupational
T Cell neoplasmsGene overexpression
Cervical CancerHPV genes
Kaposi's Sarcoma (in AIDS)virus
Cervical CancerHPV types
Transcriptional Activationgeneral oncogene
Familial polyposis coligene mutation
Gastric cancerbacteria
Hepatocellular carcinomaenvironmental
Familial melanomaGene mutation
Xeroderma Pigmentosum (skin cancer)general category of DNA repair
Liver cancertoxin from Aspergillus
Hereditary nonpolyposis colon cancermismatch DNA repair
Some immunodeficiency statesgene mutation
Retinoblastomagene mutation
Lung and Skin cancersenvironmental

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