Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
Kaposi's Sarcoma (in AIDS)virus
Liver angiosarcomaenvironmental
Acute Leukemiaenvironmental
Li-Fraumeni Syndromegene mutation
T Cell neoplasmsGene overexpression
Hereditary nonpolyposis colon cancermismatch DNA repair
Cervical CancerHPV types
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
Burkitt Lymphomavirus
Lung and Skin cancersenvironmental
T Cell leukemiavirus
Transcriptional Activationgeneral oncogene
Some immunodeficiency statesgene mutation
Cervical CancerHPV genes
Wilm's Tumorgene mutation, in kids
Hepatocellular CarcinomaResult of HBV liver damage
Cancer CausedGenes/EffectorsHints
Leukemias, thyroid, bone cancersenvironmental/occupational
Sporadic Breast Cancergene overexpression
Neurofibromatosis Type 1gene mutation
Nasopharyngeal Cancersvirus
Xeroderma Pigmentosum (skin cancer)general category of DNA repair
Familial melanomaGene mutation
Some leukemias and lymphomasinherited syndrome
Renal cancergene mutation, in adults
Hepatocellular carcinomaenvironmental
Mantle Cell lymphomat(11;14), overexpress cyclin
Familial polyposis coligene mutation
Follicular Lymphomat(14;18)
Gastric cancerbacteria
Retinoblastomagene mutation
Familial Breast Cancer, OvarianGene mutation
Liver cancertoxin from Aspergillus

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