Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
Retinoblastomagene mutation
Leukemias, thyroid, bone cancersenvironmental/occupational
Familial Breast Cancer, OvarianGene mutation
Neurofibromatosis Type 1gene mutation
Sporadic Breast Cancergene overexpression
Familial melanomaGene mutation
Mantle Cell lymphomat(11;14), overexpress cyclin
Nasopharyngeal Cancersvirus
Wilm's Tumorgene mutation, in kids
Familial polyposis coligene mutation
Kaposi's Sarcoma (in AIDS)virus
Hepatocellular carcinomaenvironmental
Some leukemias and lymphomasinherited syndrome
Renal cancergene mutation, in adults
Liver cancertoxin from Aspergillus
Cervical CancerHPV types
Hereditary nonpolyposis colon cancermismatch DNA repair
Cancer CausedGenes/EffectorsHints
Liver angiosarcomaenvironmental
Li-Fraumeni Syndromegene mutation
Transcriptional Activationgeneral oncogene
Gastric cancerbacteria
Hepatocellular CarcinomaResult of HBV liver damage
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
Burkitt Lymphomavirus
Lung and Skin cancersenvironmental
Follicular Lymphomat(14;18)
T Cell leukemiavirus
Cervical CancerHPV genes
Acute Leukemiaenvironmental
Some immunodeficiency statesgene mutation
Xeroderma Pigmentosum (skin cancer)general category of DNA repair
T Cell neoplasmsGene overexpression

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