Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
Kaposi's Sarcoma (in AIDS)virus
Wilm's Tumorgene mutation, in kids
Sporadic Breast Cancergene overexpression
T Cell neoplasmsGene overexpression
Liver angiosarcomaenvironmental
Cervical CancerHPV genes
Burkitt Lymphomavirus
Acute Leukemiaenvironmental
Leukemias, thyroid, bone cancersenvironmental/occupational
Hepatocellular CarcinomaResult of HBV liver damage
Hereditary nonpolyposis colon cancermismatch DNA repair
Familial Breast Cancer, OvarianGene mutation
Li-Fraumeni Syndromegene mutation
Xeroderma Pigmentosum (skin cancer)general category of DNA repair
Some immunodeficiency statesgene mutation
Cancer CausedGenes/EffectorsHints
Familial polyposis coligene mutation
Mantle Cell lymphomat(11;14), overexpress cyclin
Some leukemias and lymphomasinherited syndrome
Hepatocellular carcinomaenvironmental
Transcriptional Activationgeneral oncogene
Follicular Lymphomat(14;18)
Nasopharyngeal Cancersvirus
Neurofibromatosis Type 1gene mutation
Retinoblastomagene mutation
Renal cancergene mutation, in adults
T Cell leukemiavirus
Gastric cancerbacteria
Lung and Skin cancersenvironmental
Familial melanomaGene mutation
Cervical CancerHPV types
Liver cancertoxin from Aspergillus

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Created Feb 26, 2011SourceReportNominate