Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
Some leukemias and lymphomasinherited syndrome
Follicular Lymphomat(14;18)
Wilm's Tumorgene mutation, in kids
Li-Fraumeni Syndromegene mutation
Mantle Cell lymphomat(11;14), overexpress cyclin
Liver cancertoxin from Aspergillus
Xeroderma Pigmentosum (skin cancer)general category of DNA repair
Some immunodeficiency statesgene mutation
Burkitt Lymphomavirus
Nasopharyngeal Cancersvirus
Familial Breast Cancer, OvarianGene mutation
Leukemias, thyroid, bone cancersenvironmental/occupational
Cervical CancerHPV genes
Renal cancergene mutation, in adults
Transcriptional Activationgeneral oncogene
Retinoblastomagene mutation
Liver angiosarcomaenvironmental
Cancer CausedGenes/EffectorsHints
Sporadic Breast Cancergene overexpression
Hereditary nonpolyposis colon cancermismatch DNA repair
Hepatocellular carcinomaenvironmental
Cervical CancerHPV types
Neurofibromatosis Type 1gene mutation
Gastric cancerbacteria
Familial polyposis coligene mutation
Familial melanomaGene mutation
Lung and Skin cancersenvironmental
Kaposi's Sarcoma (in AIDS)virus
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
T Cell neoplasmsGene overexpression
Acute Leukemiaenvironmental
T Cell leukemiavirus
Hepatocellular CarcinomaResult of HBV liver damage

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