Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
Retinoblastomagene mutation
Liver angiosarcomaenvironmental
Hepatocellular CarcinomaResult of HBV liver damage
Hepatocellular carcinomaenvironmental
Some leukemias and lymphomasinherited syndrome
Kaposi's Sarcoma (in AIDS)virus
Familial polyposis coligene mutation
Transcriptional Activationgeneral oncogene
Gastric cancerbacteria
Hereditary nonpolyposis colon cancermismatch DNA repair
Li-Fraumeni Syndromegene mutation
Xeroderma Pigmentosum (skin cancer)general category of DNA repair
Mantle Cell lymphomat(11;14), overexpress cyclin
Renal cancergene mutation, in adults
Cervical CancerHPV types
Sporadic Breast Cancergene overexpression
Familial Breast Cancer, OvarianGene mutation
Cancer CausedGenes/EffectorsHints
Familial melanomaGene mutation
Mesotheliomaenvironmental
T Cell leukemiavirus
Neurofibromatosis Type 1gene mutation
Some immunodeficiency statesgene mutation
Cervical CancerHPV genes
Follicular Lymphomat(14;18)
T Cell neoplasmsGene overexpression
Nasopharyngeal Cancersvirus
Wilm's Tumorgene mutation, in kids
Burkitt Lymphomavirus
Liver cancertoxin from Aspergillus
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
Acute Leukemiaenvironmental
Leukemias, thyroid, bone cancersenvironmental/occupational
Lung and Skin cancersenvironmental

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