Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
T Cell neoplasmsGene overexpression
Acute Leukemiaenvironmental
Renal cancergene mutation, in adults
Familial polyposis coligene mutation
Xeroderma Pigmentosum (skin cancer)general category of DNA repair
Familial Breast Cancer, OvarianGene mutation
Gastric cancerbacteria
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
Leukemias, thyroid, bone cancersenvironmental/occupational
Some immunodeficiency statesgene mutation
Liver angiosarcomaenvironmental
Nasopharyngeal Cancersvirus
Li-Fraumeni Syndromegene mutation
Hepatocellular CarcinomaResult of HBV liver damage
Hereditary nonpolyposis colon cancermismatch DNA repair
Liver cancertoxin from Aspergillus
Burkitt Lymphomavirus
Cancer CausedGenes/EffectorsHints
Retinoblastomagene mutation
Lung and Skin cancersenvironmental
Follicular Lymphomat(14;18)
T Cell leukemiavirus
Some leukemias and lymphomasinherited syndrome
Familial melanomaGene mutation
Hepatocellular carcinomaenvironmental
Sporadic Breast Cancergene overexpression
Transcriptional Activationgeneral oncogene
Cervical CancerHPV types
Mantle Cell lymphomat(11;14), overexpress cyclin
Cervical CancerHPV genes
Kaposi's Sarcoma (in AIDS)virus
Wilm's Tumorgene mutation, in kids
Neurofibromatosis Type 1gene mutation

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