Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
Li-Fraumeni Syndromegene mutation
Nasopharyngeal Cancersvirus
Kaposi's Sarcoma (in AIDS)virus
Cervical CancerHPV genes
T Cell leukemiavirus
Cervical CancerHPV types
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
Retinoblastomagene mutation
Neurofibromatosis Type 1gene mutation
T Cell neoplasmsGene overexpression
Hepatocellular carcinomaenvironmental
Hepatocellular CarcinomaResult of HBV liver damage
Burkitt Lymphomavirus
Follicular Lymphomat(14;18)
Liver cancertoxin from Aspergillus
Leukemias, thyroid, bone cancersenvironmental/occupational
Cancer CausedGenes/EffectorsHints
Wilm's Tumorgene mutation, in kids
Lung and Skin cancersenvironmental
Familial melanomaGene mutation
Xeroderma Pigmentosum (skin cancer)general category of DNA repair
Renal cancergene mutation, in adults
Acute Leukemiaenvironmental
Mantle Cell lymphomat(11;14), overexpress cyclin
Some leukemias and lymphomasinherited syndrome
Familial Breast Cancer, OvarianGene mutation
Hereditary nonpolyposis colon cancermismatch DNA repair
Sporadic Breast Cancergene overexpression
Gastric cancerbacteria
Liver angiosarcomaenvironmental
Familial polyposis coligene mutation
Some immunodeficiency statesgene mutation
Transcriptional Activationgeneral oncogene

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