Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
Lung and Skin cancersenvironmental
Wilm's Tumorgene mutation, in kids
Familial Breast Cancer, OvarianGene mutation
Liver angiosarcomaenvironmental
Cervical CancerHPV types
Hepatocellular carcinomaenvironmental
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
Some immunodeficiency statesgene mutation
T Cell leukemiavirus
Neurofibromatosis Type 1gene mutation
Leukemias, thyroid, bone cancersenvironmental/occupational
Cervical CancerHPV genes
T Cell neoplasmsGene overexpression
Familial melanomaGene mutation
Xeroderma Pigmentosum (skin cancer)general category of DNA repair
Mesotheliomaenvironmental
Gastric cancerbacteria
Cancer CausedGenes/EffectorsHints
Sporadic Breast Cancergene overexpression
Hepatocellular CarcinomaResult of HBV liver damage
Liver cancertoxin from Aspergillus
Some leukemias and lymphomasinherited syndrome
Acute Leukemiaenvironmental
Nasopharyngeal Cancersvirus
Burkitt Lymphomavirus
Transcriptional Activationgeneral oncogene
Familial polyposis coligene mutation
Hereditary nonpolyposis colon cancermismatch DNA repair
Retinoblastomagene mutation
Follicular Lymphomat(14;18)
Kaposi's Sarcoma (in AIDS)virus
Mantle Cell lymphomat(11;14), overexpress cyclin
Renal cancergene mutation, in adults
Li-Fraumeni Syndromegene mutation

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