Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
T Cell neoplasmsGene overexpression
Hepatocellular carcinomaenvironmental
Nasopharyngeal Cancersvirus
Liver angiosarcomaenvironmental
Hereditary nonpolyposis colon cancermismatch DNA repair
Burkitt Lymphomavirus
Familial melanomaGene mutation
Xeroderma Pigmentosum (skin cancer)general category of DNA repair
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
Hepatocellular CarcinomaResult of HBV liver damage
Lung and Skin cancersenvironmental
Mantle Cell lymphomat(11;14), overexpress cyclin
Follicular Lymphomat(14;18)
Neurofibromatosis Type 1gene mutation
Transcriptional Activationgeneral oncogene
Wilm's Tumorgene mutation, in kids
Cancer CausedGenes/EffectorsHints
Kaposi's Sarcoma (in AIDS)virus
Cervical CancerHPV types
Retinoblastomagene mutation
Leukemias, thyroid, bone cancersenvironmental/occupational
T Cell leukemiavirus
Sporadic Breast Cancergene overexpression
Renal cancergene mutation, in adults
Some immunodeficiency statesgene mutation
Familial Breast Cancer, OvarianGene mutation
Some leukemias and lymphomasinherited syndrome
Li-Fraumeni Syndromegene mutation
Gastric cancerbacteria
Liver cancertoxin from Aspergillus
Acute Leukemiaenvironmental
Familial polyposis coligene mutation
Cervical CancerHPV genes

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