Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
Leukemias, thyroid, bone cancersenvironmental/occupational
Liver angiosarcomaenvironmental
Follicular Lymphomat(14;18)
Hereditary nonpolyposis colon cancermismatch DNA repair
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
Retinoblastomagene mutation
Wilm's Tumorgene mutation, in kids
Cervical CancerHPV types
Cervical CancerHPV genes
Liver cancertoxin from Aspergillus
T Cell leukemiavirus
Renal cancergene mutation, in adults
Mantle Cell lymphomat(11;14), overexpress cyclin
Hepatocellular CarcinomaResult of HBV liver damage
Transcriptional Activationgeneral oncogene
Some leukemias and lymphomasinherited syndrome
Cancer CausedGenes/EffectorsHints
Sporadic Breast Cancergene overexpression
Burkitt Lymphomavirus
Familial Breast Cancer, OvarianGene mutation
Acute Leukemiaenvironmental
Hepatocellular carcinomaenvironmental
Familial polyposis coligene mutation
Gastric cancerbacteria
Kaposi's Sarcoma (in AIDS)virus
Familial melanomaGene mutation
Some immunodeficiency statesgene mutation
Nasopharyngeal Cancersvirus
Li-Fraumeni Syndromegene mutation
Neurofibromatosis Type 1gene mutation
Lung and Skin cancersenvironmental
T Cell neoplasmsGene overexpression
Xeroderma Pigmentosum (skin cancer)general category of DNA repair

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