Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
Wilm's Tumorgene mutation, in kids
Kaposi's Sarcoma (in AIDS)virus
Xeroderma Pigmentosum (skin cancer)general category of DNA repair
Burkitt Lymphomavirus
Familial melanomaGene mutation
Hepatocellular CarcinomaResult of HBV liver damage
Liver cancertoxin from Aspergillus
Gastric cancerbacteria
Some leukemias and lymphomasinherited syndrome
Some immunodeficiency statesgene mutation
T Cell neoplasmsGene overexpression
Hereditary nonpolyposis colon cancermismatch DNA repair
Neurofibromatosis Type 1gene mutation
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
Transcriptional Activationgeneral oncogene
Liver angiosarcomaenvironmental
Familial Breast Cancer, OvarianGene mutation
Cancer CausedGenes/EffectorsHints
Nasopharyngeal Cancersvirus
Li-Fraumeni Syndromegene mutation
T Cell leukemiavirus
Mantle Cell lymphomat(11;14), overexpress cyclin
Renal cancergene mutation, in adults
Leukemias, thyroid, bone cancersenvironmental/occupational
Retinoblastomagene mutation
Sporadic Breast Cancergene overexpression
Follicular Lymphomat(14;18)
Acute Leukemiaenvironmental
Cervical CancerHPV types
Familial polyposis coligene mutation
Cervical CancerHPV genes
Hepatocellular carcinomaenvironmental
Lung and Skin cancersenvironmental

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