Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
Familial polyposis coligene mutation
Leukemias, thyroid, bone cancersenvironmental/occupational
Liver cancertoxin from Aspergillus
Some immunodeficiency statesgene mutation
Follicular Lymphomat(14;18)
Cervical CancerHPV types
Hepatocellular CarcinomaResult of HBV liver damage
Wilm's Tumorgene mutation, in kids
Retinoblastomagene mutation
Transcriptional Activationgeneral oncogene
Cervical CancerHPV genes
Lung and Skin cancersenvironmental
Li-Fraumeni Syndromegene mutation
Acute Leukemiaenvironmental
Xeroderma Pigmentosum (skin cancer)general category of DNA repair
Burkitt Lymphomavirus
Hereditary nonpolyposis colon cancermismatch DNA repair
Cancer CausedGenes/EffectorsHints
Mantle Cell lymphomat(11;14), overexpress cyclin
Familial Breast Cancer, OvarianGene mutation
T Cell leukemiavirus
Familial melanomaGene mutation
Hepatocellular carcinomaenvironmental
Gastric cancerbacteria
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
Neurofibromatosis Type 1gene mutation
T Cell neoplasmsGene overexpression
Some leukemias and lymphomasinherited syndrome
Kaposi's Sarcoma (in AIDS)virus
Renal cancergene mutation, in adults
Nasopharyngeal Cancersvirus
Liver angiosarcomaenvironmental
Sporadic Breast Cancergene overexpression

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