Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
Hepatocellular carcinomaenvironmental
Hepatocellular CarcinomaResult of HBV liver damage
Transcriptional Activationgeneral oncogene
Familial melanomaGene mutation
T Cell leukemiavirus
Familial Breast Cancer, OvarianGene mutation
Wilm's Tumorgene mutation, in kids
Gastric cancerbacteria
Lung and Skin cancersenvironmental
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
Xeroderma Pigmentosum (skin cancer)general category of DNA repair
Li-Fraumeni Syndromegene mutation
Familial polyposis coligene mutation
Nasopharyngeal Cancersvirus
Cervical CancerHPV types
Sporadic Breast Cancergene overexpression
Mantle Cell lymphomat(11;14), overexpress cyclin
Cancer CausedGenes/EffectorsHints
T Cell neoplasmsGene overexpression
Some immunodeficiency statesgene mutation
Hereditary nonpolyposis colon cancermismatch DNA repair
Liver angiosarcomaenvironmental
Burkitt Lymphomavirus
Acute Leukemiaenvironmental
Neurofibromatosis Type 1gene mutation
Leukemias, thyroid, bone cancersenvironmental/occupational
Renal cancergene mutation, in adults
Some leukemias and lymphomasinherited syndrome
Kaposi's Sarcoma (in AIDS)virus
Cervical CancerHPV genes
Follicular Lymphomat(14;18)
Retinoblastomagene mutation
Liver cancertoxin from Aspergillus

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