Oncogenic Effectors

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Can you name the oncogenic effectors?

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Cancer CausedGenes/EffectorsHints
Neurofibromatosis Type 1gene mutation
Transcriptional Activationgeneral oncogene
Familial Breast Cancer, OvarianGene mutation
Liver angiosarcomaenvironmental
Acute Leukemiaenvironmental
Chronic Myeloid Leukemia (CML)t(9;22), oncogene addiction
Familial melanomaGene mutation
Renal cancergene mutation, in adults
Kaposi's Sarcoma (in AIDS)virus
Lung and Skin cancersenvironmental
T Cell leukemiavirus
Gastric cancerbacteria
Hepatocellular carcinomaenvironmental
Some immunodeficiency statesgene mutation
T Cell neoplasmsGene overexpression
Retinoblastomagene mutation
Cancer CausedGenes/EffectorsHints
Hepatocellular CarcinomaResult of HBV liver damage
Wilm's Tumorgene mutation, in kids
Li-Fraumeni Syndromegene mutation
Follicular Lymphomat(14;18)
Mantle Cell lymphomat(11;14), overexpress cyclin
Cervical CancerHPV genes
Sporadic Breast Cancergene overexpression
Liver cancertoxin from Aspergillus
Familial polyposis coligene mutation
Nasopharyngeal Cancersvirus
Hereditary nonpolyposis colon cancermismatch DNA repair
Cervical CancerHPV types
Leukemias, thyroid, bone cancersenvironmental/occupational
Burkitt Lymphomavirus
Xeroderma Pigmentosum (skin cancer)general category of DNA repair
Some leukemias and lymphomasinherited syndrome

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Created Feb 26, 2011SourceReportNominate