8b GUG

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oligohydramnios and 'key hole' sign
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
% of simple atypical hyperplasia that progressed to cancer
Chromosome 17, 85% lifetime breast Ca risk
MC site of involvement in endometriosis
Sv consequence of anovulatory cycle
MC cystic mass in reproductive-age women
Breast duct/lobule cells that produce milk
6 months w/o period
Thin, long unilocular mass, associated with period
Rx: adjuvant therapy for ER+ premenopausal breast Ca
Molecular? Type I, simple - complex hyperplasia
Colposcopy: cells w/ inc collagen turn white w/ ?
Infection causing bladder CA
abnormal dev of chorionic villi in pregnancy can become?
MC ovarian tumor (and cancer)
normal strict morphology required to bind to?
MC composition of kidney stones
Abnormally deep implantation onto the myometrium
Appendix epididymis remnant of ?
Lady on tamoxifen w/ post-menopausal bleeding - next step?
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
MC gynecologic CA
measure seminal vesciles - dilated due to?
screening for nonpalpable breast masses
Zone sampled in pap smear and biopsy
Induce fetal lung maturity - give mom ?
MC site to endometriosis
first line hormonal therapy of metastatic breast Ca in postmeno
MCC abnml uterine bleeding in postmenopausal
e of incontinence: unstable bladder
Papillary projections surrounded by Schiller-Duval bodies
Still a cause of maternal and fetal death
MC histology of cervival CA
MC location of transitional cell cancer
MC gynecological CA worldwide
Endometrial glands/stroma implanted outside uterine cavity/walls
MCC Epididymal Orchitis in young men
Signet ring cells in ovary = ?
Tx PUV: Incise valve to damage leaflet
Chromosome of BRCA-2
Other name for ovarian fibroma
Adnexal mass in reproductive age female, first r/o?
Given to prevent CW recurrence at mastectomy site
Type of cancer after tx for mediastinal mass in college age woman
Uterine size discrepant from dates
% of complex hyperplasia that progressed to cancer
Hallmark pathological finding of granulosa cell tumots
exogenous testosterone leads to ? type of kidney stones
Tumor marker of stromal cell tumors
Condition during lactation, mimics inflammatory breast cancer
Amniotic Fluid Index >90th %ile
pau d' orange, cancer cells in dermal lymphatics
Main mode of spread of ovarian cancer
malignant germ cell tumor: beta HCG
Chemo combo for advanced bladder CA
medical tx: urge incontinence
Lowest contraceptive failure rates
Higher percent of free PSA (25%+)
If surgery unavailable for testicular torson, reduce by twisting?
C/I for anticholinergic therapy
MC infiltrating breast Ca
breast path - clown face
HPV: Binds rB allowing for cell immortalization
class of Rx for urge incontinence to tighten outlet
Tx symptomatic bone mets (prostate CA)
Tumor from dense fibroconnective tissue of the breast
HTN dx in first 20 weeks of pregnancy
Mech: Change in transport speed of the ovum
CA most strongly associated w/ obesity
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
Best available protection against STIs
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
MC tumor of myometrium
Tumor marker for choriocarcinoma, embryonal carcinoma
Dz: epidermis of nipple contains tumor cells
Malignant tumor of admixed proliferating trophoblasts, no villi
Most important RF for uterine CA
Rx: adjuvant therapy for postmenopausal breast Ca
MC breast carcinoma in situ
'blue dot' sign and pain related to inflammation
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
HRT: w/ uterus, need estrogen and ?
Tx: stimulate ovary - induce endogenous FSH release
testicular torsion perinatal only
HTN after 20 wk gestation assoc w/ proteinuria
ovarian neoplasm w/ 3 germinal layers
pain with sex
Targeted therapy for HER2+ breast CA
postmenopausal, complex hyperplasia w/ atypia - tx?
Removal of breast, pec minor and axillary lymph node
Mutation in mucinous ovarian tumors
MCC male infertility in the world
'powder burn' lesions
Grading scheme for prostatic adenocarcinoma
Bladder cancer sx in 85% of cases
MC Tx of superficial bladder cancer
% of complex atypical hyperplasia that progressed to cancer
Antigen that lyses seminal coagulum
Marker WT-1
Endometrium that has been hormonally influenced by pregnancy
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
Major SE of contraceptive implants
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
Permanent cessation of menses x1yr w/ high FSH, low E2
monoclonal ab to HER-2 neu
umbilical cord inserts into the fetal membranes
sudden huge increase in PSA likely due to?
MC neoplasm in young men
Ovarian tumor w/ KRAS and BRAF mutations
twins share chorion but one gets more blood flow
trophoblastic proliferation, fetus or fetal tissue present
BPH Rx SE: orthostasis, dizziness, fall risk
Lab value inc if patient is not making sperm
MC method of contraception
Varicocele finding on U/S
highest risk of prostate CA starting at what age?
Tx of choice for vaginal atrophy
Composition of staghorn stone
most prostate CA develops in which zone?
Rx SE: PSA drops in half, ED, loss of libido
dilatation of ducts, inspissated (thick) secretions
Assoc w/ uterine hyperplasia/CA in postmenopausal women
HPV: Degrades p53 in the host cell
Bilateral ovarian mets w/ signet ring
Tx: antagonist in breast; agonist in endometrium
Penile CA 0% in men who are ?
MC renal tumor
division of ovum after 13 days
MCC testis CA >50yo
bleeding but os is open or closed, but still viable pregnancy
best imaging modality for tubal infertility
hormonal therapy of metastatic breast Ca causing chemical castration
Syndrome: AD w/ 85% penetrance, BRCA
MC ovarian germ cell tumor
beta 2 receptors cause uterine ?
Converts androgens to estrogen
MC aneuploidy in abortuses
#1 killer of neonates
L1 proteins from HPV strains self-assemble into non-infectious units called?
Renal CA assoc w/ Von Hippel-Lindau
Most important reason fertility dec w/ female age is increasing ?
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
Targeted therapy for ER+ breast CA
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
Perimenopausal uterine bleeding, first step?
20-25% of adnexal masses, dx b/t age 10-30yo
proliferation marker in endometrial cycle
Tumor marker for endodermal sinus tumor, embryonal carcinoma
hypogonadotropic hypogonadism and anosmia
implantation into cornu of uterus or lower uterine segment
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
Progestin in BCPs derived from spironolactone
Class of Rx for urge incontinence to dec contractility
How to stage endometrial CA
Most common estrogenic ovarian tumor
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
MC site of mets in metastatic breast cancer
Origin of 90% ovarian cancers (aka MC form)
acute infection w/ obstruction -1st step?
MCC abnml uterine bleeding in adolescence
intraurethral Rx for ED
first line hormonal therapy of metastatic breast Ca in premenopausal
Appendix testes remnant of ?
Why is stage I breast Ca 10-year survival only 75%?
hormone causing ovulation
MCC UTO in male children
reflex test to triage ASCUS pap smear in women > 21
Any condition irritating the periotoneal lining inc which marker?
presence of endometrial glands in uterine myometrium
antepartum hemorrhage after 20 wks
Molecular? Type I, proliferative - simple hyperplasia
MC site of ectopic pregnant
low value w/ anovulation: failure to centrally stimulate follicular growth
malignant germ cell tumor: AFP
Kidney CA stage T4, invades
intraabdominal pregnancy, later found in a 60yo woman
Call-Exner bodies, Inhibin+
Tumor marker for dysgerminoma
elevated seminal leukocyte count aka?
Sperm with DNA damage is assoc w/ ?
Type of incontinence: neurogenic dysfunction
male contraceptive = exogenous hormone?
MC trisomy in spontaneous abortion
Most important prognostic factor in breast Ca
Special type breast CA, high grade but good prognosis
Type II endometrial carcinoma assoc w/ ?
mech of finasteride, dutasteride
Mutation assoc w/ high grade endometrioid tumors
Tx: tubal factor infertility
Prevent sz in preeclampsia
MC testicular tumor
Cells that convert adrenal steroids to estrone
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
Stage: detected from elevated PSA alone, normal DRE & TRUS
Oral contraceptive in breastfeeding woman
MCC of amenorrhea (after pregnancy)
MC type of endometrial carcinoma
IUD c/i in Wilson's disease
% of simple hyperplasia that progressed to cancer
Rx w/ SE: endometrial polyps
HTN after 20 wk w/o proteinuria
2nd most common primary site of mets to ovary
MC benign growth in breast
Worst SE of Magnesium sulfate
Proper name for 'chocolate cyst'
Tumor marker of seminoma
Type of incontinence: outlet obstruction
Flow of urine in retrograde fashion (to kidney) w/ voiding
MC histiological subtype of endometrial CA
Long acting Rx for ED
MC group of aneuploidy in spont ab
trophoblastic proliferation, cystic villi, no fetal tissue
tx: stress urinary incontinence that inc sphincter tone
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system

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Created Nov 17, 2012ReportNominate