8b GUG

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QuestionAnswerNotes
MC tumor of myometrium
Assoc w/ uterine hyperplasia/CA in postmenopausal women
ovarian neoplasm w/ 3 germinal layers
MC composition of kidney stones
Type of incontinence: outlet obstruction
Origin of 90% ovarian cancers (aka MC form)
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
MC ovarian tumor (and cancer)
MC site of involvement in endometriosis
MC cystic mass in reproductive-age women
MCC testis CA >50yo
MC ovarian germ cell tumor
Thin, long unilocular mass, associated with period
Abnormally deep implantation onto the myometrium
Tumor marker of stromal cell tumors
Rx SE: PSA drops in half, ED, loss of libido
% of complex atypical hyperplasia that progressed to cancer
Major SE of contraceptive implants
Best available protection against STIs
HRT: w/ uterus, need estrogen and ?
Adnexal mass in reproductive age female, first r/o?
CA most strongly associated w/ obesity
first line hormonal therapy of metastatic breast Ca in premenopausal
Zone sampled in pap smear and biopsy
MC location of transitional cell cancer
antepartum hemorrhage after 20 wks
HPV: Binds rB allowing for cell immortalization
Type of cancer after tx for mediastinal mass in college age woman
Tx of choice for vaginal atrophy
Sperm with DNA damage is assoc w/ ?
% of simple atypical hyperplasia that progressed to cancer
HTN dx in first 20 weeks of pregnancy
exogenous testosterone leads to ? type of kidney stones
division of ovum after 13 days
Molecular? Type I, proliferative - simple hyperplasia
Uterine size discrepant from dates
Bilateral ovarian mets w/ signet ring
MC site of ectopic pregnant
monoclonal ab to HER-2 neu
MCC UTO in male children
Perimenopausal uterine bleeding, first step?
If surgery unavailable for testicular torson, reduce by twisting?
low value w/ anovulation: failure to centrally stimulate follicular growth
6 months w/o period
testicular torsion perinatal only
Permanent cessation of menses x1yr w/ high FSH, low E2
MC histiological subtype of endometrial CA
Type II endometrial carcinoma assoc w/ ?
Cells that convert adrenal steroids to estrone
implantation into cornu of uterus or lower uterine segment
intraurethral Rx for ED
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
Any condition irritating the periotoneal lining inc which marker?
HTN after 20 wk gestation assoc w/ proteinuria
Rx: adjuvant therapy for postmenopausal breast Ca
C/I for anticholinergic therapy
HPV: Degrades p53 in the host cell
Lady on tamoxifen w/ post-menopausal bleeding - next step?
malignant germ cell tumor: beta HCG
MCC abnml uterine bleeding in adolescence
Hallmark pathological finding of granulosa cell tumots
highest risk of prostate CA starting at what age?
trophoblastic proliferation, cystic villi, no fetal tissue
Stage: detected from elevated PSA alone, normal DRE & TRUS
MC site of mets in metastatic breast cancer
BPH Rx SE: orthostasis, dizziness, fall risk
Endometrial glands/stroma implanted outside uterine cavity/walls
Composition of staghorn stone
Proper name for 'chocolate cyst'
medical tx: urge incontinence
abnormal dev of chorionic villi in pregnancy can become?
Call-Exner bodies, Inhibin+
QuestionAnswerNotes
postmenopausal, complex hyperplasia w/ atypia - tx?
Most important prognostic factor in breast Ca
Signet ring cells in ovary = ?
Why is stage I breast Ca 10-year survival only 75%?
'powder burn' lesions
Sv consequence of anovulatory cycle
MC aneuploidy in abortuses
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
hormonal therapy of metastatic breast Ca causing chemical castration
Tx symptomatic bone mets (prostate CA)
Molecular? Type I, simple - complex hyperplasia
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
class of Rx for urge incontinence to tighten outlet
dilatation of ducts, inspissated (thick) secretions
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
twins share chorion but one gets more blood flow
Tumor marker for choriocarcinoma, embryonal carcinoma
'blue dot' sign and pain related to inflammation
Bladder cancer sx in 85% of cases
Tumor marker of seminoma
L1 proteins from HPV strains self-assemble into non-infectious units called?
beta 2 receptors cause uterine ?
Malignant tumor of admixed proliferating trophoblasts, no villi
Converts androgens to estrogen
HTN after 20 wk w/o proteinuria
e of incontinence: unstable bladder
Mech: Change in transport speed of the ovum
Rx: adjuvant therapy for ER+ premenopausal breast Ca
presence of endometrial glands in uterine myometrium
Endometrium that has been hormonally influenced by pregnancy
MC group of aneuploidy in spont ab
Condition during lactation, mimics inflammatory breast cancer
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
Tx PUV: Incise valve to damage leaflet
MC infiltrating breast Ca
Mutation in mucinous ovarian tumors
Varicocele finding on U/S
MC Tx of superficial bladder cancer
Worst SE of Magnesium sulfate
Targeted therapy for HER2+ breast CA
#1 killer of neonates
hypogonadotropic hypogonadism and anosmia
MC testicular tumor
breast path - clown face
measure seminal vesciles - dilated due to?
MC trisomy in spontaneous abortion
Mutation assoc w/ high grade endometrioid tumors
Tx: antagonist in breast; agonist in endometrium
intraabdominal pregnancy, later found in a 60yo woman
Oral contraceptive in breastfeeding woman
MC STI
pau d' orange, cancer cells in dermal lymphatics
Other name for ovarian fibroma
MC benign growth in breast
malignant germ cell tumor: AFP
Flow of urine in retrograde fashion (to kidney) w/ voiding
% of complex hyperplasia that progressed to cancer
20-25% of adnexal masses, dx b/t age 10-30yo
Kidney CA stage T4, invades
Tx: stimulate ovary - induce endogenous FSH release
Marker WT-1
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
Most important RF for uterine CA
Colposcopy: cells w/ inc collagen turn white w/ ?
pain with sex
Penile CA 0% in men who are ?
normal strict morphology required to bind to?
Given to prevent CW recurrence at mastectomy site
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
most prostate CA develops in which zone?
MCC male infertility in the world
QuestionAnswerNotes
Most important reason fertility dec w/ female age is increasing ?
first line hormonal therapy of metastatic breast Ca in postmeno
elevated seminal leukocyte count aka?
Breast duct/lobule cells that produce milk
acute infection w/ obstruction -1st step?
bleeding but os is open or closed, but still viable pregnancy
Appendix epididymis remnant of ?
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
Antigen that lyses seminal coagulum
MCC of amenorrhea (after pregnancy)
Chromosome of BRCA-2
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
Renal CA assoc w/ Von Hippel-Lindau
Tumor marker for endodermal sinus tumor, embryonal carcinoma
male contraceptive = exogenous hormone?
Prevent sz in preeclampsia
MC gynecologic CA
Appendix testes remnant of ?
Lowest contraceptive failure rates
Induce fetal lung maturity - give mom ?
MCC abnml uterine bleeding in postmenopausal
Tumor marker for dysgerminoma
Most common estrogenic ovarian tumor
Special type breast CA, high grade but good prognosis
MC method of contraception
How to stage endometrial CA
Progestin in BCPs derived from spironolactone
Tx: tubal factor infertility
Rx w/ SE: endometrial polyps
Still a cause of maternal and fetal death
Ovarian tumor w/ KRAS and BRAF mutations
Targeted therapy for ER+ breast CA
screening for nonpalpable breast masses
Grading scheme for prostatic adenocarcinoma
umbilical cord inserts into the fetal membranes
MC histology of cervival CA
reflex test to triage ASCUS pap smear in women > 21
trophoblastic proliferation, fetus or fetal tissue present
Class of Rx for urge incontinence to dec contractility
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
Amniotic Fluid Index >90th %ile
Chromosome 17, 85% lifetime breast Ca risk
Type of incontinence: neurogenic dysfunction
Main mode of spread of ovarian cancer
Lab value inc if patient is not making sperm
oligohydramnios and 'key hole' sign
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
Removal of breast, pec minor and axillary lymph node
MC neoplasm in young men
IUD c/i in Wilson's disease
Chemo combo for advanced bladder CA
2nd most common primary site of mets to ovary
proliferation marker in endometrial cycle
Tumor from dense fibroconnective tissue of the breast
Dz: epidermis of nipple contains tumor cells
MC renal tumor
best imaging modality for tubal infertility
Papillary projections surrounded by Schiller-Duval bodies
MC site to endometriosis
% of simple hyperplasia that progressed to cancer
MC gynecological CA worldwide
Higher percent of free PSA (25%+)
Infection causing bladder CA
MCC Epididymal Orchitis in young men
MC type of endometrial carcinoma
tx: stress urinary incontinence that inc sphincter tone
sudden huge increase in PSA likely due to?
mech of finasteride, dutasteride
Long acting Rx for ED
Syndrome: AD w/ 85% penetrance, BRCA
hormone causing ovulation
MC breast carcinoma in situ

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Created Nov 17, 2012ReportNominate
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