8b GUG

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Can you name the 8b GUG?

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sudden huge increase in PSA likely due to?
Papillary projections surrounded by Schiller-Duval bodies
Varicocele finding on U/S
MC renal tumor
MCC testis CA >50yo
Class of Rx for urge incontinence to dec contractility
Given to prevent CW recurrence at mastectomy site
6 months w/o period
Rx: adjuvant therapy for postmenopausal breast Ca
Chromosome of BRCA-2
measure seminal vesciles - dilated due to?
Targeted therapy for HER2+ breast CA
MC ovarian germ cell tumor
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
Molecular? Type I, proliferative - simple hyperplasia
Long acting Rx for ED
MC group of aneuploidy in spont ab
MC Tx of superficial bladder cancer
pain with sex
screening for nonpalpable breast masses
pau d' orange, cancer cells in dermal lymphatics
Lab value inc if patient is not making sperm
Appendix testes remnant of ?
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
umbilical cord inserts into the fetal membranes
Cells that convert adrenal steroids to estrone
Bilateral ovarian mets w/ signet ring
elevated seminal leukocyte count aka?
Tumor marker for choriocarcinoma, embryonal carcinoma
Any condition irritating the periotoneal lining inc which marker?
MCC of amenorrhea (after pregnancy)
hormonal therapy of metastatic breast Ca causing chemical castration
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
dilatation of ducts, inspissated (thick) secretions
Why is stage I breast Ca 10-year survival only 75%?
Rx w/ SE: endometrial polyps
reflex test to triage ASCUS pap smear in women > 21
Breast duct/lobule cells that produce milk
% of complex hyperplasia that progressed to cancer
MC aneuploidy in abortuses
Oral contraceptive in breastfeeding woman
Renal CA assoc w/ Von Hippel-Lindau
Signet ring cells in ovary = ?
Type of incontinence: neurogenic dysfunction
Major SE of contraceptive implants
BPH Rx SE: orthostasis, dizziness, fall risk
MC gynecological CA worldwide
Main mode of spread of ovarian cancer
C/I for anticholinergic therapy
e of incontinence: unstable bladder
Converts androgens to estrogen
MCC abnml uterine bleeding in postmenopausal
Best available protection against STIs
MC histiological subtype of endometrial CA
#1 killer of neonates
Amniotic Fluid Index >90th %ile
% of simple hyperplasia that progressed to cancer
Tx: antagonist in breast; agonist in endometrium
Mutation assoc w/ high grade endometrioid tumors
Tumor from dense fibroconnective tissue of the breast
How to stage endometrial CA
breast path - clown face
% of simple atypical hyperplasia that progressed to cancer
Zone sampled in pap smear and biopsy
Sperm with DNA damage is assoc w/ ?
Targeted therapy for ER+ breast CA
male contraceptive = exogenous hormone?
If surgery unavailable for testicular torson, reduce by twisting?
Infection causing bladder CA
Removal of breast, pec minor and axillary lymph node
Endometrial glands/stroma implanted outside uterine cavity/walls
MC gynecologic CA
HTN after 20 wk w/o proteinuria
Still a cause of maternal and fetal death
trophoblastic proliferation, cystic villi, no fetal tissue
HTN after 20 wk gestation assoc w/ proteinuria
tx: stress urinary incontinence that inc sphincter tone
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
first line hormonal therapy of metastatic breast Ca in premenopausal
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
Colposcopy: cells w/ inc collagen turn white w/ ?
MC location of transitional cell cancer
highest risk of prostate CA starting at what age?
Syndrome: AD w/ 85% penetrance, BRCA
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
Ovarian tumor w/ KRAS and BRAF mutations
Tx symptomatic bone mets (prostate CA)
proliferation marker in endometrial cycle
division of ovum after 13 days
MC composition of kidney stones
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
Most important RF for uterine CA
malignant germ cell tumor: AFP
MC ovarian tumor (and cancer)
MC method of contraception
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
Call-Exner bodies, Inhibin+
MC cystic mass in reproductive-age women
bleeding but os is open or closed, but still viable pregnancy
Higher percent of free PSA (25%+)
Proper name for 'chocolate cyst'
MC site to endometriosis
L1 proteins from HPV strains self-assemble into non-infectious units called?
low value w/ anovulation: failure to centrally stimulate follicular growth
MC testicular tumor
Antigen that lyses seminal coagulum
implantation into cornu of uterus or lower uterine segment
Most common estrogenic ovarian tumor
Type II endometrial carcinoma assoc w/ ?
Induce fetal lung maturity - give mom ?
intraurethral Rx for ED
MC histology of cervival CA
HPV: Binds rB allowing for cell immortalization
Grading scheme for prostatic adenocarcinoma
Perimenopausal uterine bleeding, first step?
Tumor marker for dysgerminoma
MC breast carcinoma in situ
MCC UTO in male children
Worst SE of Magnesium sulfate
Molecular? Type I, simple - complex hyperplasia
Composition of staghorn stone
Tumor marker of seminoma
Tx: tubal factor infertility
MCC Epididymal Orchitis in young men
MC site of involvement in endometriosis
Mutation in mucinous ovarian tumors
exogenous testosterone leads to ? type of kidney stones
Type of cancer after tx for mediastinal mass in college age woman
Marker WT-1
2nd most common primary site of mets to ovary
Endometrium that has been hormonally influenced by pregnancy
presence of endometrial glands in uterine myometrium
Appendix epididymis remnant of ?
Kidney CA stage T4, invades
Origin of 90% ovarian cancers (aka MC form)
'blue dot' sign and pain related to inflammation
'powder burn' lesions
Rx: adjuvant therapy for ER+ premenopausal breast Ca
class of Rx for urge incontinence to tighten outlet
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
first line hormonal therapy of metastatic breast Ca in postmeno
Lowest contraceptive failure rates
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
postmenopausal, complex hyperplasia w/ atypia - tx?
Tumor marker for endodermal sinus tumor, embryonal carcinoma
% of complex atypical hyperplasia that progressed to cancer
Tx PUV: Incise valve to damage leaflet
mech of finasteride, dutasteride
Most important prognostic factor in breast Ca
best imaging modality for tubal infertility
intraabdominal pregnancy, later found in a 60yo woman
MC tumor of myometrium
20-25% of adnexal masses, dx b/t age 10-30yo
Malignant tumor of admixed proliferating trophoblasts, no villi
HRT: w/ uterus, need estrogen and ?
Penile CA 0% in men who are ?
abnormal dev of chorionic villi in pregnancy can become?
Chemo combo for advanced bladder CA
MCC male infertility in the world
MC trisomy in spontaneous abortion
ovarian neoplasm w/ 3 germinal layers
Uterine size discrepant from dates
hypogonadotropic hypogonadism and anosmia
beta 2 receptors cause uterine ?
Flow of urine in retrograde fashion (to kidney) w/ voiding
Most important reason fertility dec w/ female age is increasing ?
MC type of endometrial carcinoma
Assoc w/ uterine hyperplasia/CA in postmenopausal women
Stage: detected from elevated PSA alone, normal DRE & TRUS
CA most strongly associated w/ obesity
Condition during lactation, mimics inflammatory breast cancer
Chromosome 17, 85% lifetime breast Ca risk
Mech: Change in transport speed of the ovum
testicular torsion perinatal only
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
twins share chorion but one gets more blood flow
MC benign growth in breast
Special type breast CA, high grade but good prognosis
Dz: epidermis of nipple contains tumor cells
MC site of ectopic pregnant
Tx: stimulate ovary - induce endogenous FSH release
Adnexal mass in reproductive age female, first r/o?
HTN dx in first 20 weeks of pregnancy
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
Permanent cessation of menses x1yr w/ high FSH, low E2
Rx SE: PSA drops in half, ED, loss of libido
hormone causing ovulation
Other name for ovarian fibroma
Type of incontinence: outlet obstruction
Bladder cancer sx in 85% of cases
Progestin in BCPs derived from spironolactone
Tx of choice for vaginal atrophy
trophoblastic proliferation, fetus or fetal tissue present
MC neoplasm in young men
Abnormally deep implantation onto the myometrium
Thin, long unilocular mass, associated with period
MC site of mets in metastatic breast cancer
most prostate CA develops in which zone?
acute infection w/ obstruction -1st step?
Prevent sz in preeclampsia
antepartum hemorrhage after 20 wks
medical tx: urge incontinence
MC infiltrating breast Ca
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
MCC abnml uterine bleeding in adolescence
normal strict morphology required to bind to?
HPV: Degrades p53 in the host cell
Lady on tamoxifen w/ post-menopausal bleeding - next step?
IUD c/i in Wilson's disease
monoclonal ab to HER-2 neu
oligohydramnios and 'key hole' sign
Hallmark pathological finding of granulosa cell tumots
Sv consequence of anovulatory cycle
malignant germ cell tumor: beta HCG
Tumor marker of stromal cell tumors

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