8b GUG

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Can you name the 8b GUG?

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Tumor marker for choriocarcinoma, embryonal carcinoma
Lady on tamoxifen w/ post-menopausal bleeding - next step?
measure seminal vesciles - dilated due to?
Still a cause of maternal and fetal death
ovarian neoplasm w/ 3 germinal layers
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
Lab value inc if patient is not making sperm
MC group of aneuploidy in spont ab
MCC male infertility in the world
Syndrome: AD w/ 85% penetrance, BRCA
e of incontinence: unstable bladder
Tx PUV: Incise valve to damage leaflet
MCC Epididymal Orchitis in young men
Tumor marker of seminoma
If surgery unavailable for testicular torson, reduce by twisting?
Tx symptomatic bone mets (prostate CA)
Malignant tumor of admixed proliferating trophoblasts, no villi
Type of incontinence: outlet obstruction
Breast duct/lobule cells that produce milk
Rx SE: PSA drops in half, ED, loss of libido
Lowest contraceptive failure rates
Condition during lactation, mimics inflammatory breast cancer
Oral contraceptive in breastfeeding woman
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
Converts androgens to estrogen
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
MC cystic mass in reproductive-age women
MC site of mets in metastatic breast cancer
Tx of choice for vaginal atrophy
MC testicular tumor
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
Higher percent of free PSA (25%+)
Most important RF for uterine CA
Rx w/ SE: endometrial polyps
Most important reason fertility dec w/ female age is increasing ?
MC benign growth in breast
Bilateral ovarian mets w/ signet ring
MC method of contraception
HPV: Binds rB allowing for cell immortalization
Worst SE of Magnesium sulfate
MCC of amenorrhea (after pregnancy)
'blue dot' sign and pain related to inflammation
acute infection w/ obstruction -1st step?
MC site of involvement in endometriosis
Progestin in BCPs derived from spironolactone
HPV: Degrades p53 in the host cell
hormonal therapy of metastatic breast Ca causing chemical castration
Tx: stimulate ovary - induce endogenous FSH release
Class of Rx for urge incontinence to dec contractility
MCC testis CA >50yo
MC tumor of myometrium
implantation into cornu of uterus or lower uterine segment
postmenopausal, complex hyperplasia w/ atypia - tx?
HRT: w/ uterus, need estrogen and ?
2nd most common primary site of mets to ovary
intraurethral Rx for ED
normal strict morphology required to bind to?
twins share chorion but one gets more blood flow
20-25% of adnexal masses, dx b/t age 10-30yo
Molecular? Type I, simple - complex hyperplasia
Varicocele finding on U/S
Targeted therapy for ER+ breast CA
MCC abnml uterine bleeding in adolescence
Molecular? Type I, proliferative - simple hyperplasia
Tx: tubal factor infertility
L1 proteins from HPV strains self-assemble into non-infectious units called?
Why is stage I breast Ca 10-year survival only 75%?
monoclonal ab to HER-2 neu
Prevent sz in preeclampsia
malignant germ cell tumor: beta HCG
breast path - clown face
trophoblastic proliferation, fetus or fetal tissue present
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
Signet ring cells in ovary = ?
Infection causing bladder CA
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
Colposcopy: cells w/ inc collagen turn white w/ ?
beta 2 receptors cause uterine ?
MC composition of kidney stones
Main mode of spread of ovarian cancer
Chemo combo for advanced bladder CA
MC trisomy in spontaneous abortion
Permanent cessation of menses x1yr w/ high FSH, low E2
Assoc w/ uterine hyperplasia/CA in postmenopausal women
Removal of breast, pec minor and axillary lymph node
#1 killer of neonates
MC neoplasm in young men
Tumor marker for endodermal sinus tumor, embryonal carcinoma
MC renal tumor
IUD c/i in Wilson's disease
tx: stress urinary incontinence that inc sphincter tone
abnormal dev of chorionic villi in pregnancy can become?
MC ovarian germ cell tumor
MC infiltrating breast Ca
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
antepartum hemorrhage after 20 wks
proliferation marker in endometrial cycle
pain with sex
Other name for ovarian fibroma
Call-Exner bodies, Inhibin+
dilatation of ducts, inspissated (thick) secretions
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
Most important prognostic factor in breast Ca
Mech: Change in transport speed of the ovum
Type of cancer after tx for mediastinal mass in college age woman
mech of finasteride, dutasteride
medical tx: urge incontinence
Amniotic Fluid Index >90th %ile
Abnormally deep implantation onto the myometrium
BPH Rx SE: orthostasis, dizziness, fall risk
Flow of urine in retrograde fashion (to kidney) w/ voiding
Major SE of contraceptive implants
MC site to endometriosis
Antigen that lyses seminal coagulum
MC gynecological CA worldwide
testicular torsion perinatal only
Ovarian tumor w/ KRAS and BRAF mutations
Tumor marker of stromal cell tumors
Composition of staghorn stone
MC aneuploidy in abortuses
Long acting Rx for ED
HTN dx in first 20 weeks of pregnancy
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
Papillary projections surrounded by Schiller-Duval bodies
trophoblastic proliferation, cystic villi, no fetal tissue
MC site of ectopic pregnant
Endometrium that has been hormonally influenced by pregnancy
MC Tx of superficial bladder cancer
malignant germ cell tumor: AFP
Marker WT-1
Any condition irritating the periotoneal lining inc which marker?
Renal CA assoc w/ Von Hippel-Lindau
intraabdominal pregnancy, later found in a 60yo woman
How to stage endometrial CA
Mutation in mucinous ovarian tumors
presence of endometrial glands in uterine myometrium
HTN after 20 wk gestation assoc w/ proteinuria
% of simple atypical hyperplasia that progressed to cancer
Proper name for 'chocolate cyst'
MC histiological subtype of endometrial CA
% of simple hyperplasia that progressed to cancer
Chromosome 17, 85% lifetime breast Ca risk
Tx: antagonist in breast; agonist in endometrium
Sv consequence of anovulatory cycle
% of complex hyperplasia that progressed to cancer
exogenous testosterone leads to ? type of kidney stones
MC type of endometrial carcinoma
Tumor from dense fibroconnective tissue of the breast
most prostate CA develops in which zone?
Bladder cancer sx in 85% of cases
Given to prevent CW recurrence at mastectomy site
Stage: detected from elevated PSA alone, normal DRE & TRUS
Origin of 90% ovarian cancers (aka MC form)
low value w/ anovulation: failure to centrally stimulate follicular growth
hormone causing ovulation
Dz: epidermis of nipple contains tumor cells
class of Rx for urge incontinence to tighten outlet
Appendix epididymis remnant of ?
MC histology of cervival CA
MC location of transitional cell cancer
Uterine size discrepant from dates
Special type breast CA, high grade but good prognosis
umbilical cord inserts into the fetal membranes
division of ovum after 13 days
Chromosome of BRCA-2
MC breast carcinoma in situ
Best available protection against STIs
Rx: adjuvant therapy for ER+ premenopausal breast Ca
Adnexal mass in reproductive age female, first r/o?
pau d' orange, cancer cells in dermal lymphatics
elevated seminal leukocyte count aka?
Kidney CA stage T4, invades
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
Grading scheme for prostatic adenocarcinoma
best imaging modality for tubal infertility
'powder burn' lesions
male contraceptive = exogenous hormone?
reflex test to triage ASCUS pap smear in women > 21
HTN after 20 wk w/o proteinuria
Type of incontinence: neurogenic dysfunction
Hallmark pathological finding of granulosa cell tumots
Tumor marker for dysgerminoma
first line hormonal therapy of metastatic breast Ca in postmeno
Targeted therapy for HER2+ breast CA
Most common estrogenic ovarian tumor
6 months w/o period
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
Penile CA 0% in men who are ?
bleeding but os is open or closed, but still viable pregnancy
MC gynecologic CA
Mutation assoc w/ high grade endometrioid tumors
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
Endometrial glands/stroma implanted outside uterine cavity/walls
MC ovarian tumor (and cancer)
Sperm with DNA damage is assoc w/ ?
oligohydramnios and 'key hole' sign
sudden huge increase in PSA likely due to?
Rx: adjuvant therapy for postmenopausal breast Ca
highest risk of prostate CA starting at what age?
% of complex atypical hyperplasia that progressed to cancer
CA most strongly associated w/ obesity
Appendix testes remnant of ?
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
MCC abnml uterine bleeding in postmenopausal
C/I for anticholinergic therapy
Zone sampled in pap smear and biopsy
Perimenopausal uterine bleeding, first step?
Type II endometrial carcinoma assoc w/ ?
Cells that convert adrenal steroids to estrone
Induce fetal lung maturity - give mom ?
Thin, long unilocular mass, associated with period
first line hormonal therapy of metastatic breast Ca in premenopausal
screening for nonpalpable breast masses
hypogonadotropic hypogonadism and anosmia
MCC UTO in male children

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