8b GUG

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MC histiological subtype of endometrial CA
Chromosome of BRCA-2
Rx SE: PSA drops in half, ED, loss of libido
Rx: adjuvant therapy for postmenopausal breast Ca
normal strict morphology required to bind to?
If surgery unavailable for testicular torson, reduce by twisting?
Call-Exner bodies, Inhibin+
Worst SE of Magnesium sulfate
MC composition of kidney stones
Penile CA 0% in men who are ?
Tumor marker for choriocarcinoma, embryonal carcinoma
2nd most common primary site of mets to ovary
class of Rx for urge incontinence to tighten outlet
Malignant tumor of admixed proliferating trophoblasts, no villi
Permanent cessation of menses x1yr w/ high FSH, low E2
Tx symptomatic bone mets (prostate CA)
MC histology of cervival CA
Lady on tamoxifen w/ post-menopausal bleeding - next step?
highest risk of prostate CA starting at what age?
MC gynecologic CA
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
Cells that convert adrenal steroids to estrone
Higher percent of free PSA (25%+)
MC renal tumor
elevated seminal leukocyte count aka?
Breast duct/lobule cells that produce milk
bleeding but os is open or closed, but still viable pregnancy
Tx PUV: Incise valve to damage leaflet
reflex test to triage ASCUS pap smear in women > 21
exogenous testosterone leads to ? type of kidney stones
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
Ovarian tumor w/ KRAS and BRAF mutations
MCC UTO in male children
acute infection w/ obstruction -1st step?
testicular torsion perinatal only
Given to prevent CW recurrence at mastectomy site
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
Targeted therapy for HER2+ breast CA
Tumor marker for dysgerminoma
medical tx: urge incontinence
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
Stage: detected from elevated PSA alone, normal DRE & TRUS
Lab value inc if patient is not making sperm
Sv consequence of anovulatory cycle
umbilical cord inserts into the fetal membranes
intraurethral Rx for ED
screening for nonpalpable breast masses
Bilateral ovarian mets w/ signet ring
MC site of ectopic pregnant
hormone causing ovulation
Tumor marker of stromal cell tumors
Origin of 90% ovarian cancers (aka MC form)
dilatation of ducts, inspissated (thick) secretions
Chromosome 17, 85% lifetime breast Ca risk
Prevent sz in preeclampsia
breast path - clown face
L1 proteins from HPV strains self-assemble into non-infectious units called?
Other name for ovarian fibroma
division of ovum after 13 days
MC tumor of myometrium
MCC Epididymal Orchitis in young men
Molecular? Type I, proliferative - simple hyperplasia
Papillary projections surrounded by Schiller-Duval bodies
tx: stress urinary incontinence that inc sphincter tone
Why is stage I breast Ca 10-year survival only 75%?
Condition during lactation, mimics inflammatory breast cancer
Best available protection against STIs
Induce fetal lung maturity - give mom ?
'powder burn' lesions
e of incontinence: unstable bladder
Tx: tubal factor infertility
MC method of contraception
CA most strongly associated w/ obesity
Any condition irritating the periotoneal lining inc which marker?
Tx of choice for vaginal atrophy
Thin, long unilocular mass, associated with period
IUD c/i in Wilson's disease
Adnexal mass in reproductive age female, first r/o?
HPV: Degrades p53 in the host cell
MC site to endometriosis
best imaging modality for tubal infertility
intraabdominal pregnancy, later found in a 60yo woman
Perimenopausal uterine bleeding, first step?
trophoblastic proliferation, fetus or fetal tissue present
Proper name for 'chocolate cyst'
MC neoplasm in young men
mech of finasteride, dutasteride
Colposcopy: cells w/ inc collagen turn white w/ ?
How to stage endometrial CA
Appendix epididymis remnant of ?
Converts androgens to estrogen
MC breast carcinoma in situ
Rx w/ SE: endometrial polyps
C/I for anticholinergic therapy
Renal CA assoc w/ Von Hippel-Lindau
measure seminal vesciles - dilated due to?
MC site of mets in metastatic breast cancer
Lowest contraceptive failure rates
oligohydramnios and 'key hole' sign
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
pau d' orange, cancer cells in dermal lymphatics
MC trisomy in spontaneous abortion
Flow of urine in retrograde fashion (to kidney) w/ voiding
Abnormally deep implantation onto the myometrium
MCC testis CA >50yo
Varicocele finding on U/S
Mech: Change in transport speed of the ovum
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
Infection causing bladder CA
Mutation in mucinous ovarian tumors
MC infiltrating breast Ca
proliferation marker in endometrial cycle
MC ovarian tumor (and cancer)
Targeted therapy for ER+ breast CA
Major SE of contraceptive implants
Endometrium that has been hormonally influenced by pregnancy
Most important prognostic factor in breast Ca
HPV: Binds rB allowing for cell immortalization
MCC abnml uterine bleeding in postmenopausal
Oral contraceptive in breastfeeding woman
% of simple atypical hyperplasia that progressed to cancer
beta 2 receptors cause uterine ?
HTN dx in first 20 weeks of pregnancy
Tumor marker of seminoma
MC cystic mass in reproductive-age women
Type of incontinence: outlet obstruction
#1 killer of neonates
Type II endometrial carcinoma assoc w/ ?
HTN after 20 wk gestation assoc w/ proteinuria
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
antepartum hemorrhage after 20 wks
Most important reason fertility dec w/ female age is increasing ?
MCC abnml uterine bleeding in adolescence
Syndrome: AD w/ 85% penetrance, BRCA
Chemo combo for advanced bladder CA
Assoc w/ uterine hyperplasia/CA in postmenopausal women
Uterine size discrepant from dates
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
pain with sex
MC aneuploidy in abortuses
Tx: stimulate ovary - induce endogenous FSH release
Tumor from dense fibroconnective tissue of the breast
Most common estrogenic ovarian tumor
Sperm with DNA damage is assoc w/ ?
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
% of complex hyperplasia that progressed to cancer
postmenopausal, complex hyperplasia w/ atypia - tx?
% of complex atypical hyperplasia that progressed to cancer
Main mode of spread of ovarian cancer
male contraceptive = exogenous hormone?
first line hormonal therapy of metastatic breast Ca in postmeno
Signet ring cells in ovary = ?
MCC male infertility in the world
low value w/ anovulation: failure to centrally stimulate follicular growth
MC gynecological CA worldwide
MC type of endometrial carcinoma
Bladder cancer sx in 85% of cases
HRT: w/ uterus, need estrogen and ?
MC site of involvement in endometriosis
twins share chorion but one gets more blood flow
Antigen that lyses seminal coagulum
Marker WT-1
trophoblastic proliferation, cystic villi, no fetal tissue
Type of incontinence: neurogenic dysfunction
Tx: antagonist in breast; agonist in endometrium
Mutation assoc w/ high grade endometrioid tumors
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
Long acting Rx for ED
Rx: adjuvant therapy for ER+ premenopausal breast Ca
Composition of staghorn stone
most prostate CA develops in which zone?
abnormal dev of chorionic villi in pregnancy can become?
BPH Rx SE: orthostasis, dizziness, fall risk
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
ovarian neoplasm w/ 3 germinal layers
Most important RF for uterine CA
6 months w/o period
HTN after 20 wk w/o proteinuria
MC location of transitional cell cancer
Molecular? Type I, simple - complex hyperplasia
% of simple hyperplasia that progressed to cancer
implantation into cornu of uterus or lower uterine segment
MC Tx of superficial bladder cancer
Grading scheme for prostatic adenocarcinoma
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
malignant germ cell tumor: AFP
Class of Rx for urge incontinence to dec contractility
malignant germ cell tumor: beta HCG
Dz: epidermis of nipple contains tumor cells
MC group of aneuploidy in spont ab
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
hormonal therapy of metastatic breast Ca causing chemical castration
Special type breast CA, high grade but good prognosis
sudden huge increase in PSA likely due to?
hypogonadotropic hypogonadism and anosmia
20-25% of adnexal masses, dx b/t age 10-30yo
presence of endometrial glands in uterine myometrium
MCC of amenorrhea (after pregnancy)
Type of cancer after tx for mediastinal mass in college age woman
Appendix testes remnant of ?
Tumor marker for endodermal sinus tumor, embryonal carcinoma
Kidney CA stage T4, invades
Amniotic Fluid Index >90th %ile
MC benign growth in breast
Still a cause of maternal and fetal death
Removal of breast, pec minor and axillary lymph node
Zone sampled in pap smear and biopsy
monoclonal ab to HER-2 neu
first line hormonal therapy of metastatic breast Ca in premenopausal
Hallmark pathological finding of granulosa cell tumots
MC testicular tumor
Progestin in BCPs derived from spironolactone
'blue dot' sign and pain related to inflammation
Endometrial glands/stroma implanted outside uterine cavity/walls
MC ovarian germ cell tumor

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Created Nov 17, 2012ReportNominate