8b GUG

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QuestionAnswerNotes
IUD c/i in Wilson's disease
hormone causing ovulation
Targeted therapy for ER+ breast CA
highest risk of prostate CA starting at what age?
Worst SE of Magnesium sulfate
MC gynecologic CA
Best available protection against STIs
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
Chromosome of BRCA-2
Tx symptomatic bone mets (prostate CA)
L1 proteins from HPV strains self-assemble into non-infectious units called?
Most important RF for uterine CA
measure seminal vesciles - dilated due to?
Targeted therapy for HER2+ breast CA
Abnormally deep implantation onto the myometrium
Special type breast CA, high grade but good prognosis
Condition during lactation, mimics inflammatory breast cancer
tx: stress urinary incontinence that inc sphincter tone
Other name for ovarian fibroma
HTN dx in first 20 weeks of pregnancy
malignant germ cell tumor: beta HCG
Adnexal mass in reproductive age female, first r/o?
Most common estrogenic ovarian tumor
HTN after 20 wk gestation assoc w/ proteinuria
C/I for anticholinergic therapy
first line hormonal therapy of metastatic breast Ca in postmeno
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
MC trisomy in spontaneous abortion
ovarian neoplasm w/ 3 germinal layers
MC cystic mass in reproductive-age women
Any condition irritating the periotoneal lining inc which marker?
Kidney CA stage T4, invades
Chromosome 17, 85% lifetime breast Ca risk
Bilateral ovarian mets w/ signet ring
MC Tx of superficial bladder cancer
beta 2 receptors cause uterine ?
umbilical cord inserts into the fetal membranes
MC histology of cervival CA
% of simple hyperplasia that progressed to cancer
hormonal therapy of metastatic breast Ca causing chemical castration
Colposcopy: cells w/ inc collagen turn white w/ ?
MC benign growth in breast
MC site of involvement in endometriosis
Lab value inc if patient is not making sperm
MC breast carcinoma in situ
Grading scheme for prostatic adenocarcinoma
% of complex hyperplasia that progressed to cancer
Rx SE: PSA drops in half, ED, loss of libido
Cells that convert adrenal steroids to estrone
Flow of urine in retrograde fashion (to kidney) w/ voiding
Antigen that lyses seminal coagulum
trophoblastic proliferation, cystic villi, no fetal tissue
% of simple atypical hyperplasia that progressed to cancer
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
low value w/ anovulation: failure to centrally stimulate follicular growth
intraurethral Rx for ED
Mutation assoc w/ high grade endometrioid tumors
antepartum hemorrhage after 20 wks
Long acting Rx for ED
Sv consequence of anovulatory cycle
20-25% of adnexal masses, dx b/t age 10-30yo
abnormal dev of chorionic villi in pregnancy can become?
MC group of aneuploidy in spont ab
MC gynecological CA worldwide
Most important prognostic factor in breast Ca
Uterine size discrepant from dates
Appendix epididymis remnant of ?
Mutation in mucinous ovarian tumors
postmenopausal, complex hyperplasia w/ atypia - tx?
Tumor from dense fibroconnective tissue of the breast
Marker WT-1
first line hormonal therapy of metastatic breast Ca in premenopausal
QuestionAnswerNotes
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
Type of cancer after tx for mediastinal mass in college age woman
MC composition of kidney stones
MCC of amenorrhea (after pregnancy)
implantation into cornu of uterus or lower uterine segment
MC histiological subtype of endometrial CA
Composition of staghorn stone
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
Rx w/ SE: endometrial polyps
MCC abnml uterine bleeding in adolescence
breast path - clown face
Papillary projections surrounded by Schiller-Duval bodies
Tumor marker for choriocarcinoma, embryonal carcinoma
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
Type II endometrial carcinoma assoc w/ ?
hypogonadotropic hypogonadism and anosmia
MC renal tumor
Infection causing bladder CA
Class of Rx for urge incontinence to dec contractility
testicular torsion perinatal only
Major SE of contraceptive implants
Tumor marker for endodermal sinus tumor, embryonal carcinoma
Origin of 90% ovarian cancers (aka MC form)
CA most strongly associated w/ obesity
Given to prevent CW recurrence at mastectomy site
Most important reason fertility dec w/ female age is increasing ?
MCC testis CA >50yo
Still a cause of maternal and fetal death
Chemo combo for advanced bladder CA
2nd most common primary site of mets to ovary
Varicocele finding on U/S
Endometrial glands/stroma implanted outside uterine cavity/walls
'blue dot' sign and pain related to inflammation
proliferation marker in endometrial cycle
Higher percent of free PSA (25%+)
Converts androgens to estrogen
Malignant tumor of admixed proliferating trophoblasts, no villi
Tx: antagonist in breast; agonist in endometrium
dilatation of ducts, inspissated (thick) secretions
Hallmark pathological finding of granulosa cell tumots
#1 killer of neonates
MC aneuploidy in abortuses
MC infiltrating breast Ca
HRT: w/ uterus, need estrogen and ?
Mech: Change in transport speed of the ovum
mech of finasteride, dutasteride
MC neoplasm in young men
medical tx: urge incontinence
Penile CA 0% in men who are ?
trophoblastic proliferation, fetus or fetal tissue present
most prostate CA develops in which zone?
pain with sex
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
'powder burn' lesions
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
Amniotic Fluid Index >90th %ile
Ovarian tumor w/ KRAS and BRAF mutations
Type of incontinence: outlet obstruction
Stage: detected from elevated PSA alone, normal DRE & TRUS
exogenous testosterone leads to ? type of kidney stones
MCC male infertility in the world
MC location of transitional cell cancer
e of incontinence: unstable bladder
MCC UTO in male children
sudden huge increase in PSA likely due to?
Signet ring cells in ovary = ?
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
MC testicular tumor
Sperm with DNA damage is assoc w/ ?
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
Permanent cessation of menses x1yr w/ high FSH, low E2
Progestin in BCPs derived from spironolactone
QuestionAnswerNotes
6 months w/o period
MC type of endometrial carcinoma
MC tumor of myometrium
MCC abnml uterine bleeding in postmenopausal
Lowest contraceptive failure rates
twins share chorion but one gets more blood flow
Assoc w/ uterine hyperplasia/CA in postmenopausal women
MC site to endometriosis
Why is stage I breast Ca 10-year survival only 75%?
Appendix testes remnant of ?
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
Tumor marker of seminoma
Type of incontinence: neurogenic dysfunction
Dz: epidermis of nipple contains tumor cells
HPV: Binds rB allowing for cell immortalization
Induce fetal lung maturity - give mom ?
Tumor marker of stromal cell tumors
Tx of choice for vaginal atrophy
MC STI
Call-Exner bodies, Inhibin+
division of ovum after 13 days
elevated seminal leukocyte count aka?
MC ovarian germ cell tumor
Prevent sz in preeclampsia
Molecular? Type I, proliferative - simple hyperplasia
presence of endometrial glands in uterine myometrium
% of complex atypical hyperplasia that progressed to cancer
male contraceptive = exogenous hormone?
Tx: stimulate ovary - induce endogenous FSH release
pau d' orange, cancer cells in dermal lymphatics
best imaging modality for tubal infertility
normal strict morphology required to bind to?
bleeding but os is open or closed, but still viable pregnancy
reflex test to triage ASCUS pap smear in women > 21
Molecular? Type I, simple - complex hyperplasia
MC site of mets in metastatic breast cancer
How to stage endometrial CA
acute infection w/ obstruction -1st step?
intraabdominal pregnancy, later found in a 60yo woman
HPV: Degrades p53 in the host cell
MC ovarian tumor (and cancer)
HTN after 20 wk w/o proteinuria
Lady on tamoxifen w/ post-menopausal bleeding - next step?
If surgery unavailable for testicular torson, reduce by twisting?
screening for nonpalpable breast masses
Endometrium that has been hormonally influenced by pregnancy
Removal of breast, pec minor and axillary lymph node
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
Rx: adjuvant therapy for ER+ premenopausal breast Ca
Oral contraceptive in breastfeeding woman
class of Rx for urge incontinence to tighten outlet
MC method of contraception
Syndrome: AD w/ 85% penetrance, BRCA
MC site of ectopic pregnant
Rx: adjuvant therapy for postmenopausal breast Ca
Thin, long unilocular mass, associated with period
Renal CA assoc w/ Von Hippel-Lindau
Perimenopausal uterine bleeding, first step?
monoclonal ab to HER-2 neu
Proper name for 'chocolate cyst'
BPH Rx SE: orthostasis, dizziness, fall risk
Zone sampled in pap smear and biopsy
Breast duct/lobule cells that produce milk
MCC Epididymal Orchitis in young men
Main mode of spread of ovarian cancer
Bladder cancer sx in 85% of cases
malignant germ cell tumor: AFP
oligohydramnios and 'key hole' sign
Tx: tubal factor infertility
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
Tumor marker for dysgerminoma
Tx PUV: Incise valve to damage leaflet

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Created Nov 17, 2012ReportNominate
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