8b GUG

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QuestionAnswerNotes
Type II endometrial carcinoma assoc w/ ?
Abnormally deep implantation onto the myometrium
HRT: w/ uterus, need estrogen and ?
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
Rx SE: PSA drops in half, ED, loss of libido
proliferation marker in endometrial cycle
Main mode of spread of ovarian cancer
Molecular? Type I, simple - complex hyperplasia
MC trisomy in spontaneous abortion
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
MCC abnml uterine bleeding in adolescence
Endometrial glands/stroma implanted outside uterine cavity/walls
exogenous testosterone leads to ? type of kidney stones
low value w/ anovulation: failure to centrally stimulate follicular growth
Worst SE of Magnesium sulfate
Malignant tumor of admixed proliferating trophoblasts, no villi
Lady on tamoxifen w/ post-menopausal bleeding - next step?
intraurethral Rx for ED
MC type of endometrial carcinoma
Oral contraceptive in breastfeeding woman
Tumor marker for choriocarcinoma, embryonal carcinoma
Lowest contraceptive failure rates
Most important prognostic factor in breast Ca
Mutation in mucinous ovarian tumors
MC testicular tumor
Prevent sz in preeclampsia
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
tx: stress urinary incontinence that inc sphincter tone
twins share chorion but one gets more blood flow
Condition during lactation, mimics inflammatory breast cancer
Endometrium that has been hormonally influenced by pregnancy
Tx symptomatic bone mets (prostate CA)
Composition of staghorn stone
How to stage endometrial CA
Flow of urine in retrograde fashion (to kidney) w/ voiding
Ovarian tumor w/ KRAS and BRAF mutations
Dz: epidermis of nipple contains tumor cells
Marker WT-1
medical tx: urge incontinence
elevated seminal leukocyte count aka?
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
Cells that convert adrenal steroids to estrone
MC group of aneuploidy in spont ab
MC site of mets in metastatic breast cancer
Sv consequence of anovulatory cycle
beta 2 receptors cause uterine ?
umbilical cord inserts into the fetal membranes
'powder burn' lesions
MC aneuploidy in abortuses
Other name for ovarian fibroma
MC benign growth in breast
hormone causing ovulation
Special type breast CA, high grade but good prognosis
Uterine size discrepant from dates
BPH Rx SE: orthostasis, dizziness, fall risk
Why is stage I breast Ca 10-year survival only 75%?
Appendix testes remnant of ?
malignant germ cell tumor: beta HCG
pau d' orange, cancer cells in dermal lymphatics
HTN dx in first 20 weeks of pregnancy
Rx: adjuvant therapy for ER+ premenopausal breast Ca
Type of cancer after tx for mediastinal mass in college age woman
most prostate CA develops in which zone?
hormonal therapy of metastatic breast Ca causing chemical castration
trophoblastic proliferation, cystic villi, no fetal tissue
screening for nonpalpable breast masses
#1 killer of neonates
Mutation assoc w/ high grade endometrioid tumors
Zone sampled in pap smear and biopsy
Colposcopy: cells w/ inc collagen turn white w/ ?
Most important RF for uterine CA
QuestionAnswerNotes
Tx of choice for vaginal atrophy
Bilateral ovarian mets w/ signet ring
Appendix epididymis remnant of ?
MC STI
MC neoplasm in young men
Chromosome of BRCA-2
Tumor marker of seminoma
normal strict morphology required to bind to?
'blue dot' sign and pain related to inflammation
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
If surgery unavailable for testicular torson, reduce by twisting?
Removal of breast, pec minor and axillary lymph node
MC method of contraception
Origin of 90% ovarian cancers (aka MC form)
Tumor from dense fibroconnective tissue of the breast
Grading scheme for prostatic adenocarcinoma
measure seminal vesciles - dilated due to?
Hallmark pathological finding of granulosa cell tumots
HTN after 20 wk gestation assoc w/ proteinuria
MC site of involvement in endometriosis
Breast duct/lobule cells that produce milk
Given to prevent CW recurrence at mastectomy site
Class of Rx for urge incontinence to dec contractility
monoclonal ab to HER-2 neu
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
MC tumor of myometrium
Type of incontinence: neurogenic dysfunction
MC ovarian germ cell tumor
IUD c/i in Wilson's disease
highest risk of prostate CA starting at what age?
MC histiological subtype of endometrial CA
presence of endometrial glands in uterine myometrium
MC gynecologic CA
Any condition irritating the periotoneal lining inc which marker?
HPV: Binds rB allowing for cell immortalization
Stage: detected from elevated PSA alone, normal DRE & TRUS
Tx PUV: Incise valve to damage leaflet
Still a cause of maternal and fetal death
Chromosome 17, 85% lifetime breast Ca risk
MC composition of kidney stones
Targeted therapy for ER+ breast CA
Bladder cancer sx in 85% of cases
best imaging modality for tubal infertility
sudden huge increase in PSA likely due to?
Papillary projections surrounded by Schiller-Duval bodies
MCC abnml uterine bleeding in postmenopausal
% of simple atypical hyperplasia that progressed to cancer
MC site to endometriosis
Converts androgens to estrogen
20-25% of adnexal masses, dx b/t age 10-30yo
Type of incontinence: outlet obstruction
MCC testis CA >50yo
MC renal tumor
% of simple hyperplasia that progressed to cancer
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
Progestin in BCPs derived from spironolactone
ovarian neoplasm w/ 3 germinal layers
Best available protection against STIs
malignant germ cell tumor: AFP
intraabdominal pregnancy, later found in a 60yo woman
L1 proteins from HPV strains self-assemble into non-infectious units called?
Tumor marker of stromal cell tumors
dilatation of ducts, inspissated (thick) secretions
Tx: stimulate ovary - induce endogenous FSH release
Varicocele finding on U/S
Rx: adjuvant therapy for postmenopausal breast Ca
mech of finasteride, dutasteride
breast path - clown face
MC infiltrating breast Ca
acute infection w/ obstruction -1st step?
Long acting Rx for ED
QuestionAnswerNotes
Most important reason fertility dec w/ female age is increasing ?
Rx w/ SE: endometrial polyps
% of complex atypical hyperplasia that progressed to cancer
abnormal dev of chorionic villi in pregnancy can become?
division of ovum after 13 days
Tx: antagonist in breast; agonist in endometrium
HTN after 20 wk w/o proteinuria
Sperm with DNA damage is assoc w/ ?
MCC of amenorrhea (after pregnancy)
Adnexal mass in reproductive age female, first r/o?
Targeted therapy for HER2+ breast CA
hypogonadotropic hypogonadism and anosmia
Lab value inc if patient is not making sperm
MC breast carcinoma in situ
Thin, long unilocular mass, associated with period
pain with sex
oligohydramnios and 'key hole' sign
Tumor marker for endodermal sinus tumor, embryonal carcinoma
Antigen that lyses seminal coagulum
MC Tx of superficial bladder cancer
Most common estrogenic ovarian tumor
MCC Epididymal Orchitis in young men
HPV: Degrades p53 in the host cell
2nd most common primary site of mets to ovary
class of Rx for urge incontinence to tighten outlet
Tumor marker for dysgerminoma
MC location of transitional cell cancer
MCC male infertility in the world
Assoc w/ uterine hyperplasia/CA in postmenopausal women
Tx: tubal factor infertility
C/I for anticholinergic therapy
Perimenopausal uterine bleeding, first step?
male contraceptive = exogenous hormone?
Syndrome: AD w/ 85% penetrance, BRCA
Renal CA assoc w/ Von Hippel-Lindau
Penile CA 0% in men who are ?
postmenopausal, complex hyperplasia w/ atypia - tx?
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
MC gynecological CA worldwide
MC cystic mass in reproductive-age women
reflex test to triage ASCUS pap smear in women > 21
Proper name for 'chocolate cyst'
Mech: Change in transport speed of the ovum
first line hormonal therapy of metastatic breast Ca in postmeno
MC ovarian tumor (and cancer)
Kidney CA stage T4, invades
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
testicular torsion perinatal only
Signet ring cells in ovary = ?
Higher percent of free PSA (25%+)
Call-Exner bodies, Inhibin+
trophoblastic proliferation, fetus or fetal tissue present
% of complex hyperplasia that progressed to cancer
CA most strongly associated w/ obesity
Permanent cessation of menses x1yr w/ high FSH, low E2
e of incontinence: unstable bladder
Amniotic Fluid Index >90th %ile
bleeding but os is open or closed, but still viable pregnancy
Major SE of contraceptive implants
first line hormonal therapy of metastatic breast Ca in premenopausal
Induce fetal lung maturity - give mom ?
Chemo combo for advanced bladder CA
MCC UTO in male children
6 months w/o period
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
antepartum hemorrhage after 20 wks
Infection causing bladder CA
MC site of ectopic pregnant
MC histology of cervival CA
Molecular? Type I, proliferative - simple hyperplasia
implantation into cornu of uterus or lower uterine segment

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Created Nov 17, 2012ReportNominate
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