8b GUG

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QuestionAnswerNotes
measure seminal vesciles - dilated due to?
Tumor from dense fibroconnective tissue of the breast
malignant germ cell tumor: beta HCG
proliferation marker in endometrial cycle
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
Composition of staghorn stone
Origin of 90% ovarian cancers (aka MC form)
low value w/ anovulation: failure to centrally stimulate follicular growth
Targeted therapy for ER+ breast CA
Kidney CA stage T4, invades
% of simple atypical hyperplasia that progressed to cancer
Bilateral ovarian mets w/ signet ring
Syndrome: AD w/ 85% penetrance, BRCA
Most important prognostic factor in breast Ca
normal strict morphology required to bind to?
umbilical cord inserts into the fetal membranes
HPV: Binds rB allowing for cell immortalization
Condition during lactation, mimics inflammatory breast cancer
sudden huge increase in PSA likely due to?
bleeding but os is open or closed, but still viable pregnancy
Rx SE: PSA drops in half, ED, loss of libido
HPV: Degrades p53 in the host cell
Most important RF for uterine CA
pain with sex
medical tx: urge incontinence
MCC abnml uterine bleeding in adolescence
Tx PUV: Incise valve to damage leaflet
Adnexal mass in reproductive age female, first r/o?
division of ovum after 13 days
first line hormonal therapy of metastatic breast Ca in postmeno
implantation into cornu of uterus or lower uterine segment
pau d' orange, cancer cells in dermal lymphatics
MC site of ectopic pregnant
Amniotic Fluid Index >90th %ile
Ovarian tumor w/ KRAS and BRAF mutations
Tx: stimulate ovary - induce endogenous FSH release
Tx symptomatic bone mets (prostate CA)
L1 proteins from HPV strains self-assemble into non-infectious units called?
Dz: epidermis of nipple contains tumor cells
testicular torsion perinatal only
Malignant tumor of admixed proliferating trophoblasts, no villi
Type of incontinence: neurogenic dysfunction
Higher percent of free PSA (25%+)
MC ovarian tumor (and cancer)
#1 killer of neonates
antepartum hemorrhage after 20 wks
MC benign growth in breast
ovarian neoplasm w/ 3 germinal layers
IUD c/i in Wilson's disease
Lab value inc if patient is not making sperm
HTN after 20 wk gestation assoc w/ proteinuria
Molecular? Type I, proliferative - simple hyperplasia
hormonal therapy of metastatic breast Ca causing chemical castration
Tumor marker for dysgerminoma
Most common estrogenic ovarian tumor
Marker WT-1
Penile CA 0% in men who are ?
presence of endometrial glands in uterine myometrium
MCC Epididymal Orchitis in young men
class of Rx for urge incontinence to tighten outlet
MCC of amenorrhea (after pregnancy)
Call-Exner bodies, Inhibin+
breast path - clown face
MCC abnml uterine bleeding in postmenopausal
Stage: detected from elevated PSA alone, normal DRE & TRUS
MC renal tumor
MC gynecologic CA
intraabdominal pregnancy, later found in a 60yo woman
MC cystic mass in reproductive-age women
Main mode of spread of ovarian cancer
Chromosome 17, 85% lifetime breast Ca risk
Given to prevent CW recurrence at mastectomy site
QuestionAnswerNotes
mech of finasteride, dutasteride
How to stage endometrial CA
MC composition of kidney stones
C/I for anticholinergic therapy
monoclonal ab to HER-2 neu
abnormal dev of chorionic villi in pregnancy can become?
Proper name for 'chocolate cyst'
Appendix testes remnant of ?
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
HRT: w/ uterus, need estrogen and ?
hypogonadotropic hypogonadism and anosmia
Tx: antagonist in breast; agonist in endometrium
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
hormone causing ovulation
If surgery unavailable for testicular torson, reduce by twisting?
Induce fetal lung maturity - give mom ?
MC type of endometrial carcinoma
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
exogenous testosterone leads to ? type of kidney stones
malignant germ cell tumor: AFP
MC STI
MC trisomy in spontaneous abortion
Uterine size discrepant from dates
Tx: tubal factor infertility
Chromosome of BRCA-2
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
Why is stage I breast Ca 10-year survival only 75%?
Mutation in mucinous ovarian tumors
Cells that convert adrenal steroids to estrone
Signet ring cells in ovary = ?
oligohydramnios and 'key hole' sign
Type of incontinence: outlet obstruction
Infection causing bladder CA
Abnormally deep implantation onto the myometrium
Grading scheme for prostatic adenocarcinoma
screening for nonpalpable breast masses
CA most strongly associated w/ obesity
% of complex hyperplasia that progressed to cancer
Lady on tamoxifen w/ post-menopausal bleeding - next step?
first line hormonal therapy of metastatic breast Ca in premenopausal
trophoblastic proliferation, fetus or fetal tissue present
MC location of transitional cell cancer
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
Bladder cancer sx in 85% of cases
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
MCC testis CA >50yo
MC histology of cervival CA
beta 2 receptors cause uterine ?
MCC male infertility in the world
MC aneuploidy in abortuses
best imaging modality for tubal infertility
Converts androgens to estrogen
MC ovarian germ cell tumor
Renal CA assoc w/ Von Hippel-Lindau
Still a cause of maternal and fetal death
'powder burn' lesions
dilatation of ducts, inspissated (thick) secretions
Rx: adjuvant therapy for ER+ premenopausal breast Ca
Varicocele finding on U/S
HTN after 20 wk w/o proteinuria
Sv consequence of anovulatory cycle
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
Other name for ovarian fibroma
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
acute infection w/ obstruction -1st step?
Perimenopausal uterine bleeding, first step?
Most important reason fertility dec w/ female age is increasing ?
Oral contraceptive in breastfeeding woman
MC site to endometriosis
Tumor marker of stromal cell tumors
male contraceptive = exogenous hormone?
Molecular? Type I, simple - complex hyperplasia
QuestionAnswerNotes
MC site of mets in metastatic breast cancer
Tumor marker for endodermal sinus tumor, embryonal carcinoma
% of simple hyperplasia that progressed to cancer
Removal of breast, pec minor and axillary lymph node
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
MC infiltrating breast Ca
6 months w/o period
Class of Rx for urge incontinence to dec contractility
MC testicular tumor
MC gynecological CA worldwide
Worst SE of Magnesium sulfate
MC Tx of superficial bladder cancer
MC method of contraception
e of incontinence: unstable bladder
'blue dot' sign and pain related to inflammation
Assoc w/ uterine hyperplasia/CA in postmenopausal women
Best available protection against STIs
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
elevated seminal leukocyte count aka?
Zone sampled in pap smear and biopsy
Sperm with DNA damage is assoc w/ ?
MCC UTO in male children
trophoblastic proliferation, cystic villi, no fetal tissue
Lowest contraceptive failure rates
Mutation assoc w/ high grade endometrioid tumors
Permanent cessation of menses x1yr w/ high FSH, low E2
Tumor marker for choriocarcinoma, embryonal carcinoma
Thin, long unilocular mass, associated with period
Rx: adjuvant therapy for postmenopausal breast Ca
Colposcopy: cells w/ inc collagen turn white w/ ?
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
MC neoplasm in young men
Flow of urine in retrograde fashion (to kidney) w/ voiding
Breast duct/lobule cells that produce milk
MC site of involvement in endometriosis
Any condition irritating the periotoneal lining inc which marker?
Tumor marker of seminoma
20-25% of adnexal masses, dx b/t age 10-30yo
Targeted therapy for HER2+ breast CA
Type of cancer after tx for mediastinal mass in college age woman
BPH Rx SE: orthostasis, dizziness, fall risk
MC group of aneuploidy in spont ab
Type II endometrial carcinoma assoc w/ ?
Progestin in BCPs derived from spironolactone
Antigen that lyses seminal coagulum
Mech: Change in transport speed of the ovum
tx: stress urinary incontinence that inc sphincter tone
2nd most common primary site of mets to ovary
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
highest risk of prostate CA starting at what age?
MC breast carcinoma in situ
Hallmark pathological finding of granulosa cell tumots
% of complex atypical hyperplasia that progressed to cancer
Endometrial glands/stroma implanted outside uterine cavity/walls
Major SE of contraceptive implants
MC tumor of myometrium
Long acting Rx for ED
intraurethral Rx for ED
Chemo combo for advanced bladder CA
most prostate CA develops in which zone?
Prevent sz in preeclampsia
HTN dx in first 20 weeks of pregnancy
Endometrium that has been hormonally influenced by pregnancy
postmenopausal, complex hyperplasia w/ atypia - tx?
twins share chorion but one gets more blood flow
Appendix epididymis remnant of ?
Tx of choice for vaginal atrophy
Rx w/ SE: endometrial polyps
reflex test to triage ASCUS pap smear in women > 21
MC histiological subtype of endometrial CA
Papillary projections surrounded by Schiller-Duval bodies
Special type breast CA, high grade but good prognosis

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