8b GUG

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Kidney CA stage T4, invades
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
MCC of amenorrhea (after pregnancy)
Papillary projections surrounded by Schiller-Duval bodies
% of complex atypical hyperplasia that progressed to cancer
tx: stress urinary incontinence that inc sphincter tone
division of ovum after 13 days
Most important prognostic factor in breast Ca
proliferation marker in endometrial cycle
hypogonadotropic hypogonadism and anosmia
class of Rx for urge incontinence to tighten outlet
Amniotic Fluid Index >90th %ile
Zone sampled in pap smear and biopsy
Main mode of spread of ovarian cancer
Converts androgens to estrogen
Class of Rx for urge incontinence to dec contractility
Mech: Change in transport speed of the ovum
HPV: Binds rB allowing for cell immortalization
MC composition of kidney stones
acute infection w/ obstruction -1st step?
MC gynecological CA worldwide
e of incontinence: unstable bladder
Mutation in mucinous ovarian tumors
#1 killer of neonates
ovarian neoplasm w/ 3 germinal layers
Mutation assoc w/ high grade endometrioid tumors
exogenous testosterone leads to ? type of kidney stones
% of simple atypical hyperplasia that progressed to cancer
Tx: tubal factor infertility
Tumor marker for dysgerminoma
Dz: epidermis of nipple contains tumor cells
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
Varicocele finding on U/S
Tumor marker of seminoma
Most common estrogenic ovarian tumor
Lady on tamoxifen w/ post-menopausal bleeding - next step?
Tumor from dense fibroconnective tissue of the breast
MC benign growth in breast
abnormal dev of chorionic villi in pregnancy can become?
MC testicular tumor
Type of incontinence: neurogenic dysfunction
Chromosome 17, 85% lifetime breast Ca risk
MC trisomy in spontaneous abortion
trophoblastic proliferation, cystic villi, no fetal tissue
malignant germ cell tumor: beta HCG
MC renal tumor
beta 2 receptors cause uterine ?
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
MCC UTO in male children
reflex test to triage ASCUS pap smear in women > 21
2nd most common primary site of mets to ovary
bleeding but os is open or closed, but still viable pregnancy
Perimenopausal uterine bleeding, first step?
Endometrial glands/stroma implanted outside uterine cavity/walls
Colposcopy: cells w/ inc collagen turn white w/ ?
Tumor marker for choriocarcinoma, embryonal carcinoma
Type of incontinence: outlet obstruction
Induce fetal lung maturity - give mom ?
screening for nonpalpable breast masses
20-25% of adnexal masses, dx b/t age 10-30yo
'blue dot' sign and pain related to inflammation
intraurethral Rx for ED
HTN dx in first 20 weeks of pregnancy
Uterine size discrepant from dates
Other name for ovarian fibroma
Sperm with DNA damage is assoc w/ ?
trophoblastic proliferation, fetus or fetal tissue present
highest risk of prostate CA starting at what age?
Stage: detected from elevated PSA alone, normal DRE & TRUS
Cells that convert adrenal steroids to estrone
most prostate CA develops in which zone?
HTN after 20 wk gestation assoc w/ proteinuria
MC breast carcinoma in situ
postmenopausal, complex hyperplasia w/ atypia - tx?
L1 proteins from HPV strains self-assemble into non-infectious units called?
Molecular? Type I, proliferative - simple hyperplasia
MC type of endometrial carcinoma
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
implantation into cornu of uterus or lower uterine segment
HRT: w/ uterus, need estrogen and ?
Renal CA assoc w/ Von Hippel-Lindau
MC site of involvement in endometriosis
Grading scheme for prostatic adenocarcinoma
intraabdominal pregnancy, later found in a 60yo woman
MC histiological subtype of endometrial CA
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
mech of finasteride, dutasteride
first line hormonal therapy of metastatic breast Ca in postmeno
testicular torsion perinatal only
MCC male infertility in the world
MC method of contraception
MC neoplasm in young men
Most important RF for uterine CA
breast path - clown face
Still a cause of maternal and fetal death
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
Marker WT-1
MC ovarian germ cell tumor
Special type breast CA, high grade but good prognosis
Call-Exner bodies, Inhibin+
C/I for anticholinergic therapy
MC site of ectopic pregnant
MC cystic mass in reproductive-age women
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
hormone causing ovulation
twins share chorion but one gets more blood flow
Malignant tumor of admixed proliferating trophoblasts, no villi
MC location of transitional cell cancer
Adnexal mass in reproductive age female, first r/o?
malignant germ cell tumor: AFP
Assoc w/ uterine hyperplasia/CA in postmenopausal women
elevated seminal leukocyte count aka?
umbilical cord inserts into the fetal membranes
MC Tx of superficial bladder cancer
normal strict morphology required to bind to?
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
medical tx: urge incontinence
low value w/ anovulation: failure to centrally stimulate follicular growth
Most important reason fertility dec w/ female age is increasing ?
Composition of staghorn stone
6 months w/o period
Progestin in BCPs derived from spironolactone
MC site of mets in metastatic breast cancer
Targeted therapy for HER2+ breast CA
Ovarian tumor w/ KRAS and BRAF mutations
hormonal therapy of metastatic breast Ca causing chemical castration
presence of endometrial glands in uterine myometrium
MC histology of cervival CA
Higher percent of free PSA (25%+)
Condition during lactation, mimics inflammatory breast cancer
Tumor marker of stromal cell tumors
pain with sex
Lab value inc if patient is not making sperm
Tx: antagonist in breast; agonist in endometrium
MC group of aneuploidy in spont ab
If surgery unavailable for testicular torson, reduce by twisting?
Breast duct/lobule cells that produce milk
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
Rx: adjuvant therapy for ER+ premenopausal breast Ca
MC site to endometriosis
Rx w/ SE: endometrial polyps
Signet ring cells in ovary = ?
Flow of urine in retrograde fashion (to kidney) w/ voiding
MCC testis CA >50yo
Lowest contraceptive failure rates
Thin, long unilocular mass, associated with period
MC infiltrating breast Ca
Major SE of contraceptive implants
% of simple hyperplasia that progressed to cancer
Hallmark pathological finding of granulosa cell tumots
Appendix testes remnant of ?
Rx SE: PSA drops in half, ED, loss of libido
Worst SE of Magnesium sulfate
MCC Epididymal Orchitis in young men
monoclonal ab to HER-2 neu
measure seminal vesciles - dilated due to?
Sv consequence of anovulatory cycle
male contraceptive = exogenous hormone?
How to stage endometrial CA
Tx: stimulate ovary - induce endogenous FSH release
Bladder cancer sx in 85% of cases
Abnormally deep implantation onto the myometrium
Infection causing bladder CA
Type II endometrial carcinoma assoc w/ ?
Oral contraceptive in breastfeeding woman
Best available protection against STIs
Tx symptomatic bone mets (prostate CA)
HTN after 20 wk w/o proteinuria
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
Given to prevent CW recurrence at mastectomy site
Chemo combo for advanced bladder CA
Any condition irritating the periotoneal lining inc which marker?
Targeted therapy for ER+ breast CA
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
Proper name for 'chocolate cyst'
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
Chromosome of BRCA-2
sudden huge increase in PSA likely due to?
MCC abnml uterine bleeding in adolescence
best imaging modality for tubal infertility
first line hormonal therapy of metastatic breast Ca in premenopausal
Molecular? Type I, simple - complex hyperplasia
IUD c/i in Wilson's disease
Appendix epididymis remnant of ?
MC gynecologic CA
HPV: Degrades p53 in the host cell
pau d' orange, cancer cells in dermal lymphatics
oligohydramnios and 'key hole' sign
'powder burn' lesions
Endometrium that has been hormonally influenced by pregnancy
Removal of breast, pec minor and axillary lymph node
dilatation of ducts, inspissated (thick) secretions
Permanent cessation of menses x1yr w/ high FSH, low E2
Penile CA 0% in men who are ?
MCC abnml uterine bleeding in postmenopausal
BPH Rx SE: orthostasis, dizziness, fall risk
MC aneuploidy in abortuses
MC ovarian tumor (and cancer)
Tx of choice for vaginal atrophy
antepartum hemorrhage after 20 wks
Antigen that lyses seminal coagulum
Prevent sz in preeclampsia
Bilateral ovarian mets w/ signet ring
Type of cancer after tx for mediastinal mass in college age woman
Tx PUV: Incise valve to damage leaflet
CA most strongly associated w/ obesity
Syndrome: AD w/ 85% penetrance, BRCA
Origin of 90% ovarian cancers (aka MC form)
Why is stage I breast Ca 10-year survival only 75%?
Long acting Rx for ED
Tumor marker for endodermal sinus tumor, embryonal carcinoma
Rx: adjuvant therapy for postmenopausal breast Ca
MC tumor of myometrium
% of complex hyperplasia that progressed to cancer

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Created Nov 17, 2012ReportNominate