8b GUG

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Can you name the 8b GUG?

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QuestionAnswerNotes
Dz: epidermis of nipple contains tumor cells
MCC UTO in male children
Signet ring cells in ovary = ?
Thin, long unilocular mass, associated with period
umbilical cord inserts into the fetal membranes
MCC abnml uterine bleeding in postmenopausal
malignant germ cell tumor: beta HCG
Tx PUV: Incise valve to damage leaflet
Mech: Change in transport speed of the ovum
Endometrial glands/stroma implanted outside uterine cavity/walls
Any condition irritating the periotoneal lining inc which marker?
% of simple atypical hyperplasia that progressed to cancer
Lowest contraceptive failure rates
Major SE of contraceptive implants
Given to prevent CW recurrence at mastectomy site
% of complex atypical hyperplasia that progressed to cancer
breast path - clown face
MC ovarian germ cell tumor
Hallmark pathological finding of granulosa cell tumots
HPV: Degrades p53 in the host cell
intraabdominal pregnancy, later found in a 60yo woman
'powder burn' lesions
Chromosome 17, 85% lifetime breast Ca risk
Lady on tamoxifen w/ post-menopausal bleeding - next step?
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
HTN dx in first 20 weeks of pregnancy
Targeted therapy for ER+ breast CA
HTN after 20 wk gestation assoc w/ proteinuria
CA most strongly associated w/ obesity
Call-Exner bodies, Inhibin+
Lab value inc if patient is not making sperm
MC benign growth in breast
Rx: adjuvant therapy for ER+ premenopausal breast Ca
% of complex hyperplasia that progressed to cancer
Cells that convert adrenal steroids to estrone
medical tx: urge incontinence
MC aneuploidy in abortuses
Tx of choice for vaginal atrophy
acute infection w/ obstruction -1st step?
Malignant tumor of admixed proliferating trophoblasts, no villi
Tumor marker for choriocarcinoma, embryonal carcinoma
beta 2 receptors cause uterine ?
Appendix testes remnant of ?
Main mode of spread of ovarian cancer
MCC Epididymal Orchitis in young men
Kidney CA stage T4, invades
screening for nonpalpable breast masses
Type of incontinence: neurogenic dysfunction
Type of cancer after tx for mediastinal mass in college age woman
Breast duct/lobule cells that produce milk
MCC of amenorrhea (after pregnancy)
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
6 months w/o period
Rx: adjuvant therapy for postmenopausal breast Ca
MC tumor of myometrium
Composition of staghorn stone
testicular torsion perinatal only
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
Bladder cancer sx in 85% of cases
Worst SE of Magnesium sulfate
Induce fetal lung maturity - give mom ?
Tx: tubal factor infertility
MC composition of kidney stones
MC histiological subtype of endometrial CA
reflex test to triage ASCUS pap smear in women > 21
best imaging modality for tubal infertility
Sperm with DNA damage is assoc w/ ?
Perimenopausal uterine bleeding, first step?
Renal CA assoc w/ Von Hippel-Lindau
Progestin in BCPs derived from spironolactone
bleeding but os is open or closed, but still viable pregnancy
Mutation in mucinous ovarian tumors
QuestionAnswerNotes
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
Assoc w/ uterine hyperplasia/CA in postmenopausal women
Prevent sz in preeclampsia
Long acting Rx for ED
Rx w/ SE: endometrial polyps
MC testicular tumor
2nd most common primary site of mets to ovary
low value w/ anovulation: failure to centrally stimulate follicular growth
oligohydramnios and 'key hole' sign
Tx: antagonist in breast; agonist in endometrium
HPV: Binds rB allowing for cell immortalization
Abnormally deep implantation onto the myometrium
MCC male infertility in the world
first line hormonal therapy of metastatic breast Ca in postmeno
ovarian neoplasm w/ 3 germinal layers
Tumor marker for endodermal sinus tumor, embryonal carcinoma
Converts androgens to estrogen
measure seminal vesciles - dilated due to?
Zone sampled in pap smear and biopsy
C/I for anticholinergic therapy
Stage: detected from elevated PSA alone, normal DRE & TRUS
Mutation assoc w/ high grade endometrioid tumors
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
MCC testis CA >50yo
malignant germ cell tumor: AFP
Amniotic Fluid Index >90th %ile
Syndrome: AD w/ 85% penetrance, BRCA
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
Tumor marker for dysgerminoma
Special type breast CA, high grade but good prognosis
Other name for ovarian fibroma
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
hypogonadotropic hypogonadism and anosmia
highest risk of prostate CA starting at what age?
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
hormonal therapy of metastatic breast Ca causing chemical castration
% of simple hyperplasia that progressed to cancer
HTN after 20 wk w/o proteinuria
presence of endometrial glands in uterine myometrium
MC site of involvement in endometriosis
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
Type II endometrial carcinoma assoc w/ ?
Class of Rx for urge incontinence to dec contractility
Ovarian tumor w/ KRAS and BRAF mutations
most prostate CA develops in which zone?
Penile CA 0% in men who are ?
Removal of breast, pec minor and axillary lymph node
male contraceptive = exogenous hormone?
MC gynecological CA worldwide
Type of incontinence: outlet obstruction
MC histology of cervival CA
MC group of aneuploidy in spont ab
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
pau d' orange, cancer cells in dermal lymphatics
postmenopausal, complex hyperplasia w/ atypia - tx?
Infection causing bladder CA
Varicocele finding on U/S
Rx SE: PSA drops in half, ED, loss of libido
elevated seminal leukocyte count aka?
Papillary projections surrounded by Schiller-Duval bodies
Most important RF for uterine CA
trophoblastic proliferation, cystic villi, no fetal tissue
e of incontinence: unstable bladder
Why is stage I breast Ca 10-year survival only 75%?
If surgery unavailable for testicular torson, reduce by twisting?
'blue dot' sign and pain related to inflammation
Tumor marker of seminoma
dilatation of ducts, inspissated (thick) secretions
Permanent cessation of menses x1yr w/ high FSH, low E2
MC renal tumor
Oral contraceptive in breastfeeding woman
Most common estrogenic ovarian tumor
QuestionAnswerNotes
proliferation marker in endometrial cycle
#1 killer of neonates
Marker WT-1
mech of finasteride, dutasteride
Molecular? Type I, proliferative - simple hyperplasia
MCC abnml uterine bleeding in adolescence
normal strict morphology required to bind to?
Higher percent of free PSA (25%+)
antepartum hemorrhage after 20 wks
intraurethral Rx for ED
MC STI
Endometrium that has been hormonally influenced by pregnancy
MC breast carcinoma in situ
Tumor marker of stromal cell tumors
20-25% of adnexal masses, dx b/t age 10-30yo
Bilateral ovarian mets w/ signet ring
L1 proteins from HPV strains self-assemble into non-infectious units called?
MC neoplasm in young men
hormone causing ovulation
MC site of mets in metastatic breast cancer
Condition during lactation, mimics inflammatory breast cancer
class of Rx for urge incontinence to tighten outlet
Colposcopy: cells w/ inc collagen turn white w/ ?
How to stage endometrial CA
Molecular? Type I, simple - complex hyperplasia
MC ovarian tumor (and cancer)
Chromosome of BRCA-2
monoclonal ab to HER-2 neu
Targeted therapy for HER2+ breast CA
Still a cause of maternal and fetal death
Origin of 90% ovarian cancers (aka MC form)
sudden huge increase in PSA likely due to?
MC site to endometriosis
Tx symptomatic bone mets (prostate CA)
MC trisomy in spontaneous abortion
HRT: w/ uterus, need estrogen and ?
Tumor from dense fibroconnective tissue of the breast
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
MC method of contraception
Best available protection against STIs
Flow of urine in retrograde fashion (to kidney) w/ voiding
exogenous testosterone leads to ? type of kidney stones
MC location of transitional cell cancer
MC Tx of superficial bladder cancer
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
tx: stress urinary incontinence that inc sphincter tone
twins share chorion but one gets more blood flow
Sv consequence of anovulatory cycle
Adnexal mass in reproductive age female, first r/o?
Grading scheme for prostatic adenocarcinoma
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
abnormal dev of chorionic villi in pregnancy can become?
Uterine size discrepant from dates
MC site of ectopic pregnant
MC type of endometrial carcinoma
Most important reason fertility dec w/ female age is increasing ?
MC cystic mass in reproductive-age women
Antigen that lyses seminal coagulum
trophoblastic proliferation, fetus or fetal tissue present
division of ovum after 13 days
Chemo combo for advanced bladder CA
MC gynecologic CA
Most important prognostic factor in breast Ca
first line hormonal therapy of metastatic breast Ca in premenopausal
IUD c/i in Wilson's disease
implantation into cornu of uterus or lower uterine segment
Proper name for 'chocolate cyst'
Tx: stimulate ovary - induce endogenous FSH release
BPH Rx SE: orthostasis, dizziness, fall risk
pain with sex
MC infiltrating breast Ca
Appendix epididymis remnant of ?

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