8b GUG

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QuestionAnswerNotes
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
exogenous testosterone leads to ? type of kidney stones
low value w/ anovulation: failure to centrally stimulate follicular growth
MC breast carcinoma in situ
Ovarian tumor w/ KRAS and BRAF mutations
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
Best available protection against STIs
Tx PUV: Incise valve to damage leaflet
sudden huge increase in PSA likely due to?
bleeding but os is open or closed, but still viable pregnancy
MCC Epididymal Orchitis in young men
'blue dot' sign and pain related to inflammation
medical tx: urge incontinence
Any condition irritating the periotoneal lining inc which marker?
acute infection w/ obstruction -1st step?
Bilateral ovarian mets w/ signet ring
Most important RF for uterine CA
Tx symptomatic bone mets (prostate CA)
class of Rx for urge incontinence to tighten outlet
Proper name for 'chocolate cyst'
Breast duct/lobule cells that produce milk
Tx: tubal factor infertility
HPV: Degrades p53 in the host cell
MC aneuploidy in abortuses
Mech: Change in transport speed of the ovum
Long acting Rx for ED
Other name for ovarian fibroma
CA most strongly associated w/ obesity
MC ovarian germ cell tumor
MC site of ectopic pregnant
Assoc w/ uterine hyperplasia/CA in postmenopausal women
Targeted therapy for ER+ breast CA
malignant germ cell tumor: beta HCG
MC site of mets in metastatic breast cancer
Signet ring cells in ovary = ?
normal strict morphology required to bind to?
Tx: stimulate ovary - induce endogenous FSH release
Why is stage I breast Ca 10-year survival only 75%?
Lady on tamoxifen w/ post-menopausal bleeding - next step?
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
Induce fetal lung maturity - give mom ?
Oral contraceptive in breastfeeding woman
MCC UTO in male children
Most important reason fertility dec w/ female age is increasing ?
Marker WT-1
% of complex atypical hyperplasia that progressed to cancer
Tumor marker for endodermal sinus tumor, embryonal carcinoma
Rx w/ SE: endometrial polyps
Uterine size discrepant from dates
Type of incontinence: outlet obstruction
Cells that convert adrenal steroids to estrone
Kidney CA stage T4, invades
Tumor from dense fibroconnective tissue of the breast
MCC testis CA >50yo
elevated seminal leukocyte count aka?
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
measure seminal vesciles - dilated due to?
IUD c/i in Wilson's disease
MC gynecologic CA
Condition during lactation, mimics inflammatory breast cancer
dilatation of ducts, inspissated (thick) secretions
Chromosome of BRCA-2
e of incontinence: unstable bladder
Amniotic Fluid Index >90th %ile
Varicocele finding on U/S
monoclonal ab to HER-2 neu
Progestin in BCPs derived from spironolactone
Penile CA 0% in men who are ?
Abnormally deep implantation onto the myometrium
Chemo combo for advanced bladder CA
Molecular? Type I, proliferative - simple hyperplasia
malignant germ cell tumor: AFP
QuestionAnswerNotes
MC gynecological CA worldwide
mech of finasteride, dutasteride
Origin of 90% ovarian cancers (aka MC form)
hormonal therapy of metastatic breast Ca causing chemical castration
Mutation assoc w/ high grade endometrioid tumors
Class of Rx for urge incontinence to dec contractility
Bladder cancer sx in 85% of cases
division of ovum after 13 days
MCC abnml uterine bleeding in postmenopausal
Most common estrogenic ovarian tumor
Composition of staghorn stone
Adnexal mass in reproductive age female, first r/o?
HTN after 20 wk gestation assoc w/ proteinuria
Dz: epidermis of nipple contains tumor cells
#1 killer of neonates
MC histiological subtype of endometrial CA
Higher percent of free PSA (25%+)
MC ovarian tumor (and cancer)
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
MC renal tumor
implantation into cornu of uterus or lower uterine segment
MC infiltrating breast Ca
hormone causing ovulation
HRT: w/ uterus, need estrogen and ?
Tumor marker for dysgerminoma
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
Rx SE: PSA drops in half, ED, loss of libido
MC method of contraception
How to stage endometrial CA
proliferation marker in endometrial cycle
pau d' orange, cancer cells in dermal lymphatics
trophoblastic proliferation, cystic villi, no fetal tissue
Sperm with DNA damage is assoc w/ ?
postmenopausal, complex hyperplasia w/ atypia - tx?
Prevent sz in preeclampsia
MCC of amenorrhea (after pregnancy)
Antigen that lyses seminal coagulum
hypogonadotropic hypogonadism and anosmia
MC group of aneuploidy in spont ab
Tumor marker of stromal cell tumors
MC composition of kidney stones
breast path - clown face
Hallmark pathological finding of granulosa cell tumots
HTN dx in first 20 weeks of pregnancy
Type of incontinence: neurogenic dysfunction
20-25% of adnexal masses, dx b/t age 10-30yo
Removal of breast, pec minor and axillary lymph node
L1 proteins from HPV strains self-assemble into non-infectious units called?
Renal CA assoc w/ Von Hippel-Lindau
MC location of transitional cell cancer
ovarian neoplasm w/ 3 germinal layers
MC trisomy in spontaneous abortion
first line hormonal therapy of metastatic breast Ca in postmeno
intraurethral Rx for ED
Major SE of contraceptive implants
Permanent cessation of menses x1yr w/ high FSH, low E2
MC tumor of myometrium
antepartum hemorrhage after 20 wks
HTN after 20 wk w/o proteinuria
Endometrial glands/stroma implanted outside uterine cavity/walls
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
Grading scheme for prostatic adenocarcinoma
MC site to endometriosis
Zone sampled in pap smear and biopsy
BPH Rx SE: orthostasis, dizziness, fall risk
Infection causing bladder CA
Given to prevent CW recurrence at mastectomy site
Endometrium that has been hormonally influenced by pregnancy
umbilical cord inserts into the fetal membranes
Most important prognostic factor in breast Ca
Sv consequence of anovulatory cycle
tx: stress urinary incontinence that inc sphincter tone
QuestionAnswerNotes
% of simple hyperplasia that progressed to cancer
Syndrome: AD w/ 85% penetrance, BRCA
If surgery unavailable for testicular torson, reduce by twisting?
MC Tx of superficial bladder cancer
MC benign growth in breast
MC type of endometrial carcinoma
intraabdominal pregnancy, later found in a 60yo woman
male contraceptive = exogenous hormone?
Thin, long unilocular mass, associated with period
MC testicular tumor
presence of endometrial glands in uterine myometrium
HPV: Binds rB allowing for cell immortalization
Type II endometrial carcinoma assoc w/ ?
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
beta 2 receptors cause uterine ?
Colposcopy: cells w/ inc collagen turn white w/ ?
pain with sex
MC STI
MCC abnml uterine bleeding in adolescence
Mutation in mucinous ovarian tumors
Main mode of spread of ovarian cancer
screening for nonpalpable breast masses
twins share chorion but one gets more blood flow
Stage: detected from elevated PSA alone, normal DRE & TRUS
Flow of urine in retrograde fashion (to kidney) w/ voiding
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
first line hormonal therapy of metastatic breast Ca in premenopausal
Worst SE of Magnesium sulfate
Appendix epididymis remnant of ?
highest risk of prostate CA starting at what age?
MCC male infertility in the world
Type of cancer after tx for mediastinal mass in college age woman
MC site of involvement in endometriosis
% of simple atypical hyperplasia that progressed to cancer
Chromosome 17, 85% lifetime breast Ca risk
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
MC neoplasm in young men
Malignant tumor of admixed proliferating trophoblasts, no villi
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
Perimenopausal uterine bleeding, first step?
Tumor marker of seminoma
reflex test to triage ASCUS pap smear in women > 21
trophoblastic proliferation, fetus or fetal tissue present
Call-Exner bodies, Inhibin+
Molecular? Type I, simple - complex hyperplasia
Rx: adjuvant therapy for postmenopausal breast Ca
Converts androgens to estrogen
abnormal dev of chorionic villi in pregnancy can become?
% of complex hyperplasia that progressed to cancer
best imaging modality for tubal infertility
2nd most common primary site of mets to ovary
Tumor marker for choriocarcinoma, embryonal carcinoma
Still a cause of maternal and fetal death
testicular torsion perinatal only
Rx: adjuvant therapy for ER+ premenopausal breast Ca
6 months w/o period
most prostate CA develops in which zone?
Special type breast CA, high grade but good prognosis
Tx of choice for vaginal atrophy
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
Papillary projections surrounded by Schiller-Duval bodies
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
MC cystic mass in reproductive-age women
C/I for anticholinergic therapy
Appendix testes remnant of ?
Targeted therapy for HER2+ breast CA
Tx: antagonist in breast; agonist in endometrium
MC histology of cervival CA
Lowest contraceptive failure rates
oligohydramnios and 'key hole' sign
'powder burn' lesions
Lab value inc if patient is not making sperm

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Created Nov 17, 2012ReportNominate
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