8b GUG

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Hemangioblastoma of cerebellum and retina, renal cysts and RCC
Lowest contraceptive failure rates
MCC of amenorrhea (after pregnancy)
MC testicular tumor
testicular torsion perinatal only
Permanent cessation of menses x1yr w/ high FSH, low E2
Call-Exner bodies, Inhibin+
BPH Rx SE: orthostasis, dizziness, fall risk
Why is stage I breast Ca 10-year survival only 75%?
MC type of endometrial carcinoma
Sperm with DNA damage is assoc w/ ?
mech of finasteride, dutasteride
Rx w/ SE: endometrial polyps
Type of incontinence: neurogenic dysfunction
Lab value inc if patient is not making sperm
% of simple atypical hyperplasia that progressed to cancer
Endometrium that has been hormonally influenced by pregnancy
L1 proteins from HPV strains self-assemble into non-infectious units called?
Flow of urine in retrograde fashion (to kidney) w/ voiding
breast path - clown face
Tx of choice for vaginal atrophy
Tumor marker of seminoma
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
Chromosome 17, 85% lifetime breast Ca risk
proliferation marker in endometrial cycle
MC histiological subtype of endometrial CA
Special type breast CA, high grade but good prognosis
medical tx: urge incontinence
Other name for ovarian fibroma
MCC UTO in male children
umbilical cord inserts into the fetal membranes
Mutation in mucinous ovarian tumors
Major SE of contraceptive implants
Breast duct/lobule cells that produce milk
beta 2 receptors cause uterine ?
MC neoplasm in young men
Perimenopausal uterine bleeding, first step?
Tumor marker for dysgerminoma
Oral contraceptive in breastfeeding woman
Higher percent of free PSA (25%+)
Papillary projections surrounded by Schiller-Duval bodies
Chemo combo for advanced bladder CA
Rx: adjuvant therapy for postmenopausal breast Ca
intraabdominal pregnancy, later found in a 60yo woman
MCC Epididymal Orchitis in young men
Syndrome: AD w/ 85% penetrance, BRCA
implantation into cornu of uterus or lower uterine segment
MC benign growth in breast
Tx symptomatic bone mets (prostate CA)
Adnexal mass in reproductive age female, first r/o?
Type of cancer after tx for mediastinal mass in college age woman
Malignant tumor of admixed proliferating trophoblasts, no villi
Removal of breast, pec minor and axillary lymph node
MC aneuploidy in abortuses
exogenous testosterone leads to ? type of kidney stones
trophoblastic proliferation, cystic villi, no fetal tissue
Abnormally deep implantation onto the myometrium
intraurethral Rx for ED
pain with sex
elevated seminal leukocyte count aka?
MC site of mets in metastatic breast cancer
MC trisomy in spontaneous abortion
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
Thin, long unilocular mass, associated with period
Class of Rx for urge incontinence to dec contractility
20-25% of adnexal masses, dx b/t age 10-30yo
Most important prognostic factor in breast Ca
MC infiltrating breast Ca
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
MC site of involvement in endometriosis
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
Grading scheme for prostatic adenocarcinoma
MC cystic mass in reproductive-age women
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
'powder burn' lesions
postmenopausal, complex hyperplasia w/ atypia - tx?
bleeding but os is open or closed, but still viable pregnancy
Dz: epidermis of nipple contains tumor cells
Origin of 90% ovarian cancers (aka MC form)
Renal CA assoc w/ Von Hippel-Lindau
reflex test to triage ASCUS pap smear in women > 21
Varicocele finding on U/S
C/I for anticholinergic therapy
Zone sampled in pap smear and biopsy
highest risk of prostate CA starting at what age?
Hallmark pathological finding of granulosa cell tumots
Composition of staghorn stone
best imaging modality for tubal infertility
screening for nonpalpable breast masses
Appendix testes remnant of ?
dilatation of ducts, inspissated (thick) secretions
MC group of aneuploidy in spont ab
Most common estrogenic ovarian tumor
Penile CA 0% in men who are ?
Uterine size discrepant from dates
monoclonal ab to HER-2 neu
MC tumor of myometrium
hormonal therapy of metastatic breast Ca causing chemical castration
malignant germ cell tumor: AFP
hypogonadotropic hypogonadism and anosmia
Sv consequence of anovulatory cycle
ovarian neoplasm w/ 3 germinal layers
normal strict morphology required to bind to?
Colposcopy: cells w/ inc collagen turn white w/ ?
% of simple hyperplasia that progressed to cancer
Appendix epididymis remnant of ?
Mutation assoc w/ high grade endometrioid tumors
Tumor marker of stromal cell tumors
oligohydramnios and 'key hole' sign
'blue dot' sign and pain related to inflammation
measure seminal vesciles - dilated due to?
Proper name for 'chocolate cyst'
MCC testis CA >50yo
Infection causing bladder CA
Most important RF for uterine CA
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
Worst SE of Magnesium sulfate
MC histology of cervival CA
sudden huge increase in PSA likely due to?
acute infection w/ obstruction -1st step?
MC method of contraception
Amniotic Fluid Index >90th %ile
CA most strongly associated w/ obesity
Chromosome of BRCA-2
If surgery unavailable for testicular torson, reduce by twisting?
Mech: Change in transport speed of the ovum
HTN after 20 wk gestation assoc w/ proteinuria
Rx SE: PSA drops in half, ED, loss of libido
IUD c/i in Wilson's disease
Prevent sz in preeclampsia
% of complex atypical hyperplasia that progressed to cancer
trophoblastic proliferation, fetus or fetal tissue present
Stage: detected from elevated PSA alone, normal DRE & TRUS
Kidney CA stage T4, invades
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
2nd most common primary site of mets to ovary
Molecular? Type I, simple - complex hyperplasia
first line hormonal therapy of metastatic breast Ca in postmeno
MC ovarian germ cell tumor
How to stage endometrial CA
Type of incontinence: outlet obstruction
MC breast carcinoma in situ
MCC abnml uterine bleeding in adolescence
presence of endometrial glands in uterine myometrium
class of Rx for urge incontinence to tighten outlet
6 months w/o period
antepartum hemorrhage after 20 wks
Targeted therapy for ER+ breast CA
Ovarian tumor w/ KRAS and BRAF mutations
first line hormonal therapy of metastatic breast Ca in premenopausal
MCC abnml uterine bleeding in postmenopausal
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
MCC male infertility in the world
twins share chorion but one gets more blood flow
Targeted therapy for HER2+ breast CA
Cells that convert adrenal steroids to estrone
Any condition irritating the periotoneal lining inc which marker?
division of ovum after 13 days
Tumor marker for choriocarcinoma, embryonal carcinoma
Still a cause of maternal and fetal death
MC Tx of superficial bladder cancer
Most important reason fertility dec w/ female age is increasing ?
HTN after 20 wk w/o proteinuria
HRT: w/ uterus, need estrogen and ?
Tx: antagonist in breast; agonist in endometrium
Tx: stimulate ovary - induce endogenous FSH release
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
Tx: tubal factor infertility
MC site to endometriosis
Assoc w/ uterine hyperplasia/CA in postmenopausal women
hormone causing ovulation
pau d' orange, cancer cells in dermal lymphatics
HTN dx in first 20 weeks of pregnancy
Induce fetal lung maturity - give mom ?
Long acting Rx for ED
Converts androgens to estrogen
Rx: adjuvant therapy for ER+ premenopausal breast Ca
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
Antigen that lyses seminal coagulum
MC location of transitional cell cancer
% of complex hyperplasia that progressed to cancer
most prostate CA develops in which zone?
Signet ring cells in ovary = ?
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
malignant germ cell tumor: beta HCG
Type II endometrial carcinoma assoc w/ ?
Tumor marker for endodermal sinus tumor, embryonal carcinoma
Progestin in BCPs derived from spironolactone
e of incontinence: unstable bladder
MC ovarian tumor (and cancer)
Main mode of spread of ovarian cancer
Bladder cancer sx in 85% of cases
Best available protection against STIs
MC gynecological CA worldwide
HPV: Binds rB allowing for cell immortalization
Bilateral ovarian mets w/ signet ring
Condition during lactation, mimics inflammatory breast cancer
MC gynecologic CA
HPV: Degrades p53 in the host cell
low value w/ anovulation: failure to centrally stimulate follicular growth
abnormal dev of chorionic villi in pregnancy can become?
Marker WT-1
MC renal tumor
Lady on tamoxifen w/ post-menopausal bleeding - next step?
Given to prevent CW recurrence at mastectomy site
#1 killer of neonates
Tumor from dense fibroconnective tissue of the breast
Tx PUV: Incise valve to damage leaflet
Molecular? Type I, proliferative - simple hyperplasia
male contraceptive = exogenous hormone?
MC composition of kidney stones
MC site of ectopic pregnant
tx: stress urinary incontinence that inc sphincter tone
Endometrial glands/stroma implanted outside uterine cavity/walls

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Created Nov 17, 2012ReportNominate