8b GUG

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QuestionAnswerNotes
Tumor from dense fibroconnective tissue of the breast
Lowest contraceptive failure rates
MC site to endometriosis
Worst SE of Magnesium sulfate
Renal CA assoc w/ Von Hippel-Lindau
Malignant tumor of admixed proliferating trophoblasts, no villi
Induce fetal lung maturity - give mom ?
Appendix epididymis remnant of ?
Hallmark pathological finding of granulosa cell tumots
most prostate CA develops in which zone?
Mech: Change in transport speed of the ovum
Antigen that lyses seminal coagulum
Stage: detected from elevated PSA alone, normal DRE & TRUS
Type of incontinence: neurogenic dysfunction
Kidney CA stage T4, invades
Tumor marker for choriocarcinoma, embryonal carcinoma
Major SE of contraceptive implants
Zone sampled in pap smear and biopsy
Mutation in mucinous ovarian tumors
MC Tx of superficial bladder cancer
monoclonal ab to HER-2 neu
Most important RF for uterine CA
Mutation assoc w/ high grade endometrioid tumors
Amniotic Fluid Index >90th %ile
umbilical cord inserts into the fetal membranes
twins share chorion but one gets more blood flow
medical tx: urge incontinence
Still a cause of maternal and fetal death
mech of finasteride, dutasteride
20-25% of adnexal masses, dx b/t age 10-30yo
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
MC location of transitional cell cancer
Tx: antagonist in breast; agonist in endometrium
Long acting Rx for ED
male contraceptive = exogenous hormone?
screening for nonpalpable breast masses
MC type of endometrial carcinoma
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
IUD c/i in Wilson's disease
oligohydramnios and 'key hole' sign
Breast duct/lobule cells that produce milk
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
Varicocele finding on U/S
class of Rx for urge incontinence to tighten outlet
bleeding but os is open or closed, but still viable pregnancy
Main mode of spread of ovarian cancer
Composition of staghorn stone
Bilateral ovarian mets w/ signet ring
Rx SE: PSA drops in half, ED, loss of libido
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
Endometrial glands/stroma implanted outside uterine cavity/walls
malignant germ cell tumor: beta HCG
MCC male infertility in the world
hypogonadotropic hypogonadism and anosmia
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
MC neoplasm in young men
elevated seminal leukocyte count aka?
MC tumor of myometrium
intraabdominal pregnancy, later found in a 60yo woman
Sv consequence of anovulatory cycle
Assoc w/ uterine hyperplasia/CA in postmenopausal women
MC gynecologic CA
malignant germ cell tumor: AFP
#1 killer of neonates
exogenous testosterone leads to ? type of kidney stones
Tumor marker of seminoma
Higher percent of free PSA (25%+)
Tx: stimulate ovary - induce endogenous FSH release
intraurethral Rx for ED
Tumor marker for endodermal sinus tumor, embryonal carcinoma
If surgery unavailable for testicular torson, reduce by twisting?
QuestionAnswerNotes
HTN after 20 wk w/o proteinuria
Chromosome of BRCA-2
MC testicular tumor
Most important reason fertility dec w/ female age is increasing ?
Cells that convert adrenal steroids to estrone
Tx PUV: Incise valve to damage leaflet
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
Adnexal mass in reproductive age female, first r/o?
trophoblastic proliferation, fetus or fetal tissue present
MC histiological subtype of endometrial CA
Uterine size discrepant from dates
Type of cancer after tx for mediastinal mass in college age woman
Grading scheme for prostatic adenocarcinoma
Rx: adjuvant therapy for postmenopausal breast Ca
MC trisomy in spontaneous abortion
Targeted therapy for ER+ breast CA
Signet ring cells in ovary = ?
2nd most common primary site of mets to ovary
Rx w/ SE: endometrial polyps
hormonal therapy of metastatic breast Ca causing chemical castration
Most important prognostic factor in breast Ca
Chromosome 17, 85% lifetime breast Ca risk
Any condition irritating the periotoneal lining inc which marker?
highest risk of prostate CA starting at what age?
Tumor marker for dysgerminoma
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
Why is stage I breast Ca 10-year survival only 75%?
BPH Rx SE: orthostasis, dizziness, fall risk
MC STI
'blue dot' sign and pain related to inflammation
reflex test to triage ASCUS pap smear in women > 21
Dz: epidermis of nipple contains tumor cells
ovarian neoplasm w/ 3 germinal layers
MC group of aneuploidy in spont ab
Tx symptomatic bone mets (prostate CA)
Molecular? Type I, proliferative - simple hyperplasia
e of incontinence: unstable bladder
Class of Rx for urge incontinence to dec contractility
MC composition of kidney stones
MC method of contraception
Marker WT-1
abnormal dev of chorionic villi in pregnancy can become?
% of complex atypical hyperplasia that progressed to cancer
MC ovarian tumor (and cancer)
MC site of ectopic pregnant
6 months w/o period
Best available protection against STIs
Lady on tamoxifen w/ post-menopausal bleeding - next step?
hormone causing ovulation
MCC testis CA >50yo
breast path - clown face
sudden huge increase in PSA likely due to?
acute infection w/ obstruction -1st step?
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
MCC of amenorrhea (after pregnancy)
presence of endometrial glands in uterine myometrium
Flow of urine in retrograde fashion (to kidney) w/ voiding
Papillary projections surrounded by Schiller-Duval bodies
Abnormally deep implantation onto the myometrium
low value w/ anovulation: failure to centrally stimulate follicular growth
Type of incontinence: outlet obstruction
Permanent cessation of menses x1yr w/ high FSH, low E2
antepartum hemorrhage after 20 wks
trophoblastic proliferation, cystic villi, no fetal tissue
Origin of 90% ovarian cancers (aka MC form)
HRT: w/ uterus, need estrogen and ?
implantation into cornu of uterus or lower uterine segment
MC gynecological CA worldwide
MC infiltrating breast Ca
Chemo combo for advanced bladder CA
Colposcopy: cells w/ inc collagen turn white w/ ?
MCC abnml uterine bleeding in adolescence
QuestionAnswerNotes
division of ovum after 13 days
Targeted therapy for HER2+ breast CA
C/I for anticholinergic therapy
first line hormonal therapy of metastatic breast Ca in premenopausal
Syndrome: AD w/ 85% penetrance, BRCA
How to stage endometrial CA
HPV: Degrades p53 in the host cell
MC breast carcinoma in situ
pau d' orange, cancer cells in dermal lymphatics
Appendix testes remnant of ?
CA most strongly associated w/ obesity
MC site of involvement in endometriosis
% of complex hyperplasia that progressed to cancer
Oral contraceptive in breastfeeding woman
Proper name for 'chocolate cyst'
beta 2 receptors cause uterine ?
MC histology of cervival CA
Penile CA 0% in men who are ?
HPV: Binds rB allowing for cell immortalization
MCC UTO in male children
normal strict morphology required to bind to?
MCC abnml uterine bleeding in postmenopausal
Rx: adjuvant therapy for ER+ premenopausal breast Ca
Ovarian tumor w/ KRAS and BRAF mutations
Molecular? Type I, simple - complex hyperplasia
Thin, long unilocular mass, associated with period
MC cystic mass in reproductive-age women
HTN after 20 wk gestation assoc w/ proteinuria
% of simple hyperplasia that progressed to cancer
Converts androgens to estrogen
Infection causing bladder CA
best imaging modality for tubal infertility
proliferation marker in endometrial cycle
Perimenopausal uterine bleeding, first step?
measure seminal vesciles - dilated due to?
Sperm with DNA damage is assoc w/ ?
MC benign growth in breast
Special type breast CA, high grade but good prognosis
Condition during lactation, mimics inflammatory breast cancer
'powder burn' lesions
Tx of choice for vaginal atrophy
Type II endometrial carcinoma assoc w/ ?
pain with sex
first line hormonal therapy of metastatic breast Ca in postmeno
Tumor marker of stromal cell tumors
% of simple atypical hyperplasia that progressed to cancer
Removal of breast, pec minor and axillary lymph node
L1 proteins from HPV strains self-assemble into non-infectious units called?
MC site of mets in metastatic breast cancer
Tx: tubal factor infertility
MC aneuploidy in abortuses
Call-Exner bodies, Inhibin+
MC renal tumor
HTN dx in first 20 weeks of pregnancy
testicular torsion perinatal only
Progestin in BCPs derived from spironolactone
Bladder cancer sx in 85% of cases
dilatation of ducts, inspissated (thick) secretions
MC ovarian germ cell tumor
Endometrium that has been hormonally influenced by pregnancy
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
Other name for ovarian fibroma
Prevent sz in preeclampsia
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
postmenopausal, complex hyperplasia w/ atypia - tx?
Most common estrogenic ovarian tumor
Given to prevent CW recurrence at mastectomy site
tx: stress urinary incontinence that inc sphincter tone
Lab value inc if patient is not making sperm
MCC Epididymal Orchitis in young men
Deletion or unbalanced translocation of chromosome 3 (VKL gene)

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Created Nov 17, 2012ReportNominate
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