8b GUG

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% of complex atypical hyperplasia that progressed to cancer
Rx: adjuvant therapy for ER+ premenopausal breast Ca
male contraceptive = exogenous hormone?
elevated seminal leukocyte count aka?
MCC testis CA >50yo
Lowest contraceptive failure rates
Endometrium that has been hormonally influenced by pregnancy
MCC abnml uterine bleeding in postmenopausal
Most important prognostic factor in breast Ca
malignant germ cell tumor: beta HCG
Converts androgens to estrogen
Kidney CA stage T4, invades
Type of incontinence: outlet obstruction
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
Varicocele finding on U/S
division of ovum after 13 days
'blue dot' sign and pain related to inflammation
Amniotic Fluid Index >90th %ile
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
MCC of amenorrhea (after pregnancy)
exogenous testosterone leads to ? type of kidney stones
Proper name for 'chocolate cyst'
first line hormonal therapy of metastatic breast Ca in postmeno
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
MC site to endometriosis
Other name for ovarian fibroma
MC Tx of superficial bladder cancer
Main mode of spread of ovarian cancer
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
intraabdominal pregnancy, later found in a 60yo woman
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
e of incontinence: unstable bladder
Infection causing bladder CA
dilatation of ducts, inspissated (thick) secretions
Adnexal mass in reproductive age female, first r/o?
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
6 months w/o period
Composition of staghorn stone
breast path - clown face
pain with sex
Targeted therapy for ER+ breast CA
best imaging modality for tubal infertility
HPV: Degrades p53 in the host cell
MC aneuploidy in abortuses
mech of finasteride, dutasteride
Appendix epididymis remnant of ?
low value w/ anovulation: failure to centrally stimulate follicular growth
Lady on tamoxifen w/ post-menopausal bleeding - next step?
Special type breast CA, high grade but good prognosis
Cells that convert adrenal steroids to estrone
ovarian neoplasm w/ 3 germinal layers
Syndrome: AD w/ 85% penetrance, BRCA
implantation into cornu of uterus or lower uterine segment
hormonal therapy of metastatic breast Ca causing chemical castration
MC infiltrating breast Ca
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
hormone causing ovulation
Worst SE of Magnesium sulfate
Breast duct/lobule cells that produce milk
Type of incontinence: neurogenic dysfunction
medical tx: urge incontinence
trophoblastic proliferation, fetus or fetal tissue present
MC histology of cervival CA
Malignant tumor of admixed proliferating trophoblasts, no villi
HTN after 20 wk gestation assoc w/ proteinuria
measure seminal vesciles - dilated due to?
MC site of involvement in endometriosis
C/I for anticholinergic therapy
If surgery unavailable for testicular torson, reduce by twisting?
Dz: epidermis of nipple contains tumor cells
BPH Rx SE: orthostasis, dizziness, fall risk
Long acting Rx for ED
Oral contraceptive in breastfeeding woman
#1 killer of neonates
MC type of endometrial carcinoma
proliferation marker in endometrial cycle
Endometrial glands/stroma implanted outside uterine cavity/walls
MC histiological subtype of endometrial CA
Progestin in BCPs derived from spironolactone
IUD c/i in Wilson's disease
Grading scheme for prostatic adenocarcinoma
MC tumor of myometrium
MC renal tumor
most prostate CA develops in which zone?
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
Still a cause of maternal and fetal death
Call-Exner bodies, Inhibin+
Major SE of contraceptive implants
Condition during lactation, mimics inflammatory breast cancer
Removal of breast, pec minor and axillary lymph node
Tumor marker for endodermal sinus tumor, embryonal carcinoma
MC site of ectopic pregnant
Antigen that lyses seminal coagulum
Why is stage I breast Ca 10-year survival only 75%?
HPV: Binds rB allowing for cell immortalization
Targeted therapy for HER2+ breast CA
20-25% of adnexal masses, dx b/t age 10-30yo
Type II endometrial carcinoma assoc w/ ?
Ovarian tumor w/ KRAS and BRAF mutations
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
Mutation assoc w/ high grade endometrioid tumors
monoclonal ab to HER-2 neu
Tx of choice for vaginal atrophy
MC site of mets in metastatic breast cancer
MCC abnml uterine bleeding in adolescence
Tx PUV: Incise valve to damage leaflet
MC trisomy in spontaneous abortion
MC breast carcinoma in situ
MC composition of kidney stones
Higher percent of free PSA (25%+)
twins share chorion but one gets more blood flow
L1 proteins from HPV strains self-assemble into non-infectious units called?
MC ovarian germ cell tumor
Bilateral ovarian mets w/ signet ring
Mutation in mucinous ovarian tumors
Chromosome of BRCA-2
Chromosome 17, 85% lifetime breast Ca risk
Marker WT-1
Mech: Change in transport speed of the ovum
Stage: detected from elevated PSA alone, normal DRE & TRUS
trophoblastic proliferation, cystic villi, no fetal tissue
Chemo combo for advanced bladder CA
Papillary projections surrounded by Schiller-Duval bodies
Penile CA 0% in men who are ?
abnormal dev of chorionic villi in pregnancy can become?
2nd most common primary site of mets to ovary
highest risk of prostate CA starting at what age?
MC gynecological CA worldwide
MC neoplasm in young men
Tumor marker for dysgerminoma
Hallmark pathological finding of granulosa cell tumots
Type of cancer after tx for mediastinal mass in college age woman
Thin, long unilocular mass, associated with period
Any condition irritating the periotoneal lining inc which marker?
MC ovarian tumor (and cancer)
Perimenopausal uterine bleeding, first step?
Bladder cancer sx in 85% of cases
intraurethral Rx for ED
oligohydramnios and 'key hole' sign
% of simple atypical hyperplasia that progressed to cancer
Rx w/ SE: endometrial polyps
HTN dx in first 20 weeks of pregnancy
Tumor marker of seminoma
Tx: stimulate ovary - induce endogenous FSH release
first line hormonal therapy of metastatic breast Ca in premenopausal
CA most strongly associated w/ obesity
Most important RF for uterine CA
MC cystic mass in reproductive-age women
hypogonadotropic hypogonadism and anosmia
Tx symptomatic bone mets (prostate CA)
class of Rx for urge incontinence to tighten outlet
Molecular? Type I, simple - complex hyperplasia
Most important reason fertility dec w/ female age is increasing ?
MC location of transitional cell cancer
Given to prevent CW recurrence at mastectomy site
Tx: tubal factor infertility
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
How to stage endometrial CA
% of simple hyperplasia that progressed to cancer
Rx SE: PSA drops in half, ED, loss of libido
Sperm with DNA damage is assoc w/ ?
MC testicular tumor
beta 2 receptors cause uterine ?
Most common estrogenic ovarian tumor
umbilical cord inserts into the fetal membranes
Appendix testes remnant of ?
Rx: adjuvant therapy for postmenopausal breast Ca
Sv consequence of anovulatory cycle
Prevent sz in preeclampsia
sudden huge increase in PSA likely due to?
% of complex hyperplasia that progressed to cancer
testicular torsion perinatal only
Tumor marker of stromal cell tumors
MCC Epididymal Orchitis in young men
MC method of contraception
HTN after 20 wk w/o proteinuria
postmenopausal, complex hyperplasia w/ atypia - tx?
antepartum hemorrhage after 20 wks
'powder burn' lesions
tx: stress urinary incontinence that inc sphincter tone
Molecular? Type I, proliferative - simple hyperplasia
MCC UTO in male children
screening for nonpalpable breast masses
Lab value inc if patient is not making sperm
HRT: w/ uterus, need estrogen and ?
Permanent cessation of menses x1yr w/ high FSH, low E2
Best available protection against STIs
Flow of urine in retrograde fashion (to kidney) w/ voiding
Tx: antagonist in breast; agonist in endometrium
Origin of 90% ovarian cancers (aka MC form)
Induce fetal lung maturity - give mom ?
acute infection w/ obstruction -1st step?
Zone sampled in pap smear and biopsy
pau d' orange, cancer cells in dermal lymphatics
presence of endometrial glands in uterine myometrium
MC gynecologic CA
MC benign growth in breast
Tumor from dense fibroconnective tissue of the breast
malignant germ cell tumor: AFP
Assoc w/ uterine hyperplasia/CA in postmenopausal women
Renal CA assoc w/ Von Hippel-Lindau
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
reflex test to triage ASCUS pap smear in women > 21
Uterine size discrepant from dates
Tumor marker for choriocarcinoma, embryonal carcinoma
MC group of aneuploidy in spont ab
normal strict morphology required to bind to?
bleeding but os is open or closed, but still viable pregnancy
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
Colposcopy: cells w/ inc collagen turn white w/ ?
Class of Rx for urge incontinence to dec contractility
MCC male infertility in the world
Abnormally deep implantation onto the myometrium
Signet ring cells in ovary = ?

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Created Nov 17, 2012ReportNominate