8b GUG

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QuestionAnswerNotes
Composition of staghorn stone
HRT: w/ uterus, need estrogen and ?
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
% of simple hyperplasia that progressed to cancer
MCC male infertility in the world
Induce fetal lung maturity - give mom ?
screening for nonpalpable breast masses
Higher percent of free PSA (25%+)
MC histiological subtype of endometrial CA
Marker WT-1
MC neoplasm in young men
Signet ring cells in ovary = ?
BPH Rx SE: orthostasis, dizziness, fall risk
highest risk of prostate CA starting at what age?
twins share chorion but one gets more blood flow
tx: stress urinary incontinence that inc sphincter tone
MC site of mets in metastatic breast cancer
If surgery unavailable for testicular torson, reduce by twisting?
class of Rx for urge incontinence to tighten outlet
C/I for anticholinergic therapy
'powder burn' lesions
Permanent cessation of menses x1yr w/ high FSH, low E2
HPV: Binds rB allowing for cell immortalization
Targeted therapy for HER2+ breast CA
MC composition of kidney stones
Tumor marker for dysgerminoma
6 months w/o period
Type of incontinence: outlet obstruction
Most common estrogenic ovarian tumor
Tx: antagonist in breast; agonist in endometrium
trophoblastic proliferation, fetus or fetal tissue present
% of simple atypical hyperplasia that progressed to cancer
Oral contraceptive in breastfeeding woman
pain with sex
Cells that convert adrenal steroids to estrone
beta 2 receptors cause uterine ?
HTN after 20 wk gestation assoc w/ proteinuria
Still a cause of maternal and fetal death
2nd most common primary site of mets to ovary
Grading scheme for prostatic adenocarcinoma
MC aneuploidy in abortuses
bleeding but os is open or closed, but still viable pregnancy
Mech: Change in transport speed of the ovum
Dz: epidermis of nipple contains tumor cells
L1 proteins from HPV strains self-assemble into non-infectious units called?
breast path - clown face
elevated seminal leukocyte count aka?
Type of cancer after tx for mediastinal mass in college age woman
implantation into cornu of uterus or lower uterine segment
Mutation in mucinous ovarian tumors
Converts androgens to estrogen
Long acting Rx for ED
Breast duct/lobule cells that produce milk
Lady on tamoxifen w/ post-menopausal bleeding - next step?
Major SE of contraceptive implants
intraabdominal pregnancy, later found in a 60yo woman
Amniotic Fluid Index >90th %ile
Tx symptomatic bone mets (prostate CA)
male contraceptive = exogenous hormone?
Varicocele finding on U/S
exogenous testosterone leads to ? type of kidney stones
Tumor from dense fibroconnective tissue of the breast
Tumor marker for choriocarcinoma, embryonal carcinoma
Progestin in BCPs derived from spironolactone
mech of finasteride, dutasteride
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
Most important reason fertility dec w/ female age is increasing ?
Sv consequence of anovulatory cycle
MC group of aneuploidy in spont ab
Main mode of spread of ovarian cancer
Antigen that lyses seminal coagulum
MCC UTO in male children
QuestionAnswerNotes
% of complex hyperplasia that progressed to cancer
How to stage endometrial CA
CA most strongly associated w/ obesity
Most important prognostic factor in breast Ca
umbilical cord inserts into the fetal membranes
MC histology of cervival CA
low value w/ anovulation: failure to centrally stimulate follicular growth
Renal CA assoc w/ Von Hippel-Lindau
Removal of breast, pec minor and axillary lymph node
Call-Exner bodies, Inhibin+
Kidney CA stage T4, invades
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
presence of endometrial glands in uterine myometrium
Rx: adjuvant therapy for postmenopausal breast Ca
Tx PUV: Incise valve to damage leaflet
MCC abnml uterine bleeding in adolescence
MC type of endometrial carcinoma
oligohydramnios and 'key hole' sign
malignant germ cell tumor: AFP
Papillary projections surrounded by Schiller-Duval bodies
Tumor marker of stromal cell tumors
Syndrome: AD w/ 85% penetrance, BRCA
measure seminal vesciles - dilated due to?
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
division of ovum after 13 days
Lab value inc if patient is not making sperm
Appendix epididymis remnant of ?
Molecular? Type I, proliferative - simple hyperplasia
Tx: tubal factor infertility
Tx of choice for vaginal atrophy
% of complex atypical hyperplasia that progressed to cancer
Worst SE of Magnesium sulfate
medical tx: urge incontinence
MC infiltrating breast Ca
20-25% of adnexal masses, dx b/t age 10-30yo
MC testicular tumor
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
Appendix testes remnant of ?
Bilateral ovarian mets w/ signet ring
MC breast carcinoma in situ
#1 killer of neonates
MC ovarian tumor (and cancer)
hypogonadotropic hypogonadism and anosmia
Zone sampled in pap smear and biopsy
MCC of amenorrhea (after pregnancy)
Assoc w/ uterine hyperplasia/CA in postmenopausal women
MC trisomy in spontaneous abortion
Chromosome of BRCA-2
intraurethral Rx for ED
Special type breast CA, high grade but good prognosis
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
Tx: stimulate ovary - induce endogenous FSH release
Endometrium that has been hormonally influenced by pregnancy
MC renal tumor
pau d' orange, cancer cells in dermal lymphatics
MCC testis CA >50yo
Type of incontinence: neurogenic dysfunction
MC STI
Infection causing bladder CA
Rx SE: PSA drops in half, ED, loss of libido
MC cystic mass in reproductive-age women
normal strict morphology required to bind to?
antepartum hemorrhage after 20 wks
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
trophoblastic proliferation, cystic villi, no fetal tissue
Uterine size discrepant from dates
Flow of urine in retrograde fashion (to kidney) w/ voiding
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
MC gynecologic CA
Sperm with DNA damage is assoc w/ ?
Rx: adjuvant therapy for ER+ premenopausal breast Ca
QuestionAnswerNotes
e of incontinence: unstable bladder
sudden huge increase in PSA likely due to?
Chromosome 17, 85% lifetime breast Ca risk
most prostate CA develops in which zone?
MC gynecological CA worldwide
best imaging modality for tubal infertility
Type II endometrial carcinoma assoc w/ ?
Stage: detected from elevated PSA alone, normal DRE & TRUS
Any condition irritating the periotoneal lining inc which marker?
Molecular? Type I, simple - complex hyperplasia
'blue dot' sign and pain related to inflammation
hormone causing ovulation
acute infection w/ obstruction -1st step?
IUD c/i in Wilson's disease
Class of Rx for urge incontinence to dec contractility
MC tumor of myometrium
Tumor marker of seminoma
Rx w/ SE: endometrial polyps
Origin of 90% ovarian cancers (aka MC form)
Penile CA 0% in men who are ?
Endometrial glands/stroma implanted outside uterine cavity/walls
first line hormonal therapy of metastatic breast Ca in premenopausal
testicular torsion perinatal only
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
Best available protection against STIs
abnormal dev of chorionic villi in pregnancy can become?
reflex test to triage ASCUS pap smear in women > 21
malignant germ cell tumor: beta HCG
MC site to endometriosis
HTN after 20 wk w/o proteinuria
Hallmark pathological finding of granulosa cell tumots
hormonal therapy of metastatic breast Ca causing chemical castration
Proper name for 'chocolate cyst'
Other name for ovarian fibroma
postmenopausal, complex hyperplasia w/ atypia - tx?
Adnexal mass in reproductive age female, first r/o?
Given to prevent CW recurrence at mastectomy site
Thin, long unilocular mass, associated with period
MC method of contraception
MC ovarian germ cell tumor
HTN dx in first 20 weeks of pregnancy
MC site of ectopic pregnant
Targeted therapy for ER+ breast CA
Why is stage I breast Ca 10-year survival only 75%?
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
MCC abnml uterine bleeding in postmenopausal
MC Tx of superficial bladder cancer
Colposcopy: cells w/ inc collagen turn white w/ ?
MC benign growth in breast
monoclonal ab to HER-2 neu
Abnormally deep implantation onto the myometrium
HPV: Degrades p53 in the host cell
MC site of involvement in endometriosis
Mutation assoc w/ high grade endometrioid tumors
Bladder cancer sx in 85% of cases
Prevent sz in preeclampsia
Malignant tumor of admixed proliferating trophoblasts, no villi
Ovarian tumor w/ KRAS and BRAF mutations
proliferation marker in endometrial cycle
Lowest contraceptive failure rates
dilatation of ducts, inspissated (thick) secretions
MCC Epididymal Orchitis in young men
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
ovarian neoplasm w/ 3 germinal layers
Condition during lactation, mimics inflammatory breast cancer
MC location of transitional cell cancer
Perimenopausal uterine bleeding, first step?
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
first line hormonal therapy of metastatic breast Ca in postmeno
Chemo combo for advanced bladder CA
Tumor marker for endodermal sinus tumor, embryonal carcinoma
Most important RF for uterine CA

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