8b GUG

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MCC male infertility in the world
If surgery unavailable for testicular torson, reduce by twisting?
L1 proteins from HPV strains self-assemble into non-infectious units called?
Endometrial glands/stroma implanted outside uterine cavity/walls
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
HPV: Degrades p53 in the host cell
Appendix testes remnant of ?
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
MC gynecologic CA
% of simple hyperplasia that progressed to cancer
MCC testis CA >50yo
Proper name for 'chocolate cyst'
elevated seminal leukocyte count aka?
MC method of contraception
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
monoclonal ab to HER-2 neu
Given to prevent CW recurrence at mastectomy site
Type of incontinence: outlet obstruction
male contraceptive = exogenous hormone?
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
Cells that convert adrenal steroids to estrone
Special type breast CA, high grade but good prognosis
Long acting Rx for ED
Thin, long unilocular mass, associated with period
Other name for ovarian fibroma
first line hormonal therapy of metastatic breast Ca in postmeno
MC composition of kidney stones
Chromosome of BRCA-2
#1 killer of neonates
Molecular? Type I, simple - complex hyperplasia
Most important reason fertility dec w/ female age is increasing ?
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
Oral contraceptive in breastfeeding woman
Syndrome: AD w/ 85% penetrance, BRCA
Signet ring cells in ovary = ?
HRT: w/ uterus, need estrogen and ?
MC gynecological CA worldwide
intraurethral Rx for ED
Best available protection against STIs
Penile CA 0% in men who are ?
trophoblastic proliferation, cystic villi, no fetal tissue
intraabdominal pregnancy, later found in a 60yo woman
Tx: tubal factor infertility
MC histology of cervival CA
% of complex hyperplasia that progressed to cancer
Origin of 90% ovarian cancers (aka MC form)
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
Major SE of contraceptive implants
Tx: stimulate ovary - induce endogenous FSH release
mech of finasteride, dutasteride
Flow of urine in retrograde fashion (to kidney) w/ voiding
Rx: adjuvant therapy for postmenopausal breast Ca
MC histiological subtype of endometrial CA
C/I for anticholinergic therapy
acute infection w/ obstruction -1st step?
Zone sampled in pap smear and biopsy
Tx symptomatic bone mets (prostate CA)
Antigen that lyses seminal coagulum
Tumor from dense fibroconnective tissue of the breast
MC type of endometrial carcinoma
Mutation in mucinous ovarian tumors
MC benign growth in breast
'blue dot' sign and pain related to inflammation
Main mode of spread of ovarian cancer
Bilateral ovarian mets w/ signet ring
Ovarian tumor w/ KRAS and BRAF mutations
tx: stress urinary incontinence that inc sphincter tone
sudden huge increase in PSA likely due to?
HPV: Binds rB allowing for cell immortalization
Abnormally deep implantation onto the myometrium
Papillary projections surrounded by Schiller-Duval bodies
MCC abnml uterine bleeding in adolescence
MCC UTO in male children
Malignant tumor of admixed proliferating trophoblasts, no villi
HTN after 20 wk gestation assoc w/ proteinuria
Tx PUV: Incise valve to damage leaflet
Targeted therapy for ER+ breast CA
MC infiltrating breast Ca
first line hormonal therapy of metastatic breast Ca in premenopausal
How to stage endometrial CA
Why is stage I breast Ca 10-year survival only 75%?
MC tumor of myometrium
Still a cause of maternal and fetal death
screening for nonpalpable breast masses
division of ovum after 13 days
ovarian neoplasm w/ 3 germinal layers
Sperm with DNA damage is assoc w/ ?
Uterine size discrepant from dates
highest risk of prostate CA starting at what age?
Bladder cancer sx in 85% of cases
MCC Epididymal Orchitis in young men
best imaging modality for tubal infertility
Stage: detected from elevated PSA alone, normal DRE & TRUS
Renal CA assoc w/ Von Hippel-Lindau
MC site to endometriosis
Tx: antagonist in breast; agonist in endometrium
Perimenopausal uterine bleeding, first step?
reflex test to triage ASCUS pap smear in women > 21
hypogonadotropic hypogonadism and anosmia
Amniotic Fluid Index >90th %ile
exogenous testosterone leads to ? type of kidney stones
Tumor marker for choriocarcinoma, embryonal carcinoma
Most important RF for uterine CA
Marker WT-1
MC Tx of superficial bladder cancer
abnormal dev of chorionic villi in pregnancy can become?
Colposcopy: cells w/ inc collagen turn white w/ ?
antepartum hemorrhage after 20 wks
MC testicular tumor
Rx SE: PSA drops in half, ED, loss of libido
CA most strongly associated w/ obesity
Infection causing bladder CA
MCC of amenorrhea (after pregnancy)
postmenopausal, complex hyperplasia w/ atypia - tx?
breast path - clown face
Appendix epididymis remnant of ?
umbilical cord inserts into the fetal membranes
% of complex atypical hyperplasia that progressed to cancer
Mech: Change in transport speed of the ovum
Composition of staghorn stone
Type II endometrial carcinoma assoc w/ ?
Dz: epidermis of nipple contains tumor cells
Converts androgens to estrogen
Assoc w/ uterine hyperplasia/CA in postmenopausal women
Grading scheme for prostatic adenocarcinoma
bleeding but os is open or closed, but still viable pregnancy
hormonal therapy of metastatic breast Ca causing chemical castration
MC breast carcinoma in situ
malignant germ cell tumor: AFP
Varicocele finding on U/S
Sv consequence of anovulatory cycle
2nd most common primary site of mets to ovary
class of Rx for urge incontinence to tighten outlet
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
Chromosome 17, 85% lifetime breast Ca risk
MC site of ectopic pregnant
MCC abnml uterine bleeding in postmenopausal
presence of endometrial glands in uterine myometrium
Lady on tamoxifen w/ post-menopausal bleeding - next step?
Endometrium that has been hormonally influenced by pregnancy
20-25% of adnexal masses, dx b/t age 10-30yo
MC ovarian tumor (and cancer)
Molecular? Type I, proliferative - simple hyperplasia
MC trisomy in spontaneous abortion
Mutation assoc w/ high grade endometrioid tumors
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
MC aneuploidy in abortuses
Tumor marker of stromal cell tumors
Targeted therapy for HER2+ breast CA
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
MC neoplasm in young men
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
MC ovarian germ cell tumor
Lowest contraceptive failure rates
HTN after 20 wk w/o proteinuria
'powder burn' lesions
MC location of transitional cell cancer
implantation into cornu of uterus or lower uterine segment
BPH Rx SE: orthostasis, dizziness, fall risk
IUD c/i in Wilson's disease
twins share chorion but one gets more blood flow
Condition during lactation, mimics inflammatory breast cancer
low value w/ anovulation: failure to centrally stimulate follicular growth
e of incontinence: unstable bladder
Type of cancer after tx for mediastinal mass in college age woman
testicular torsion perinatal only
Rx: adjuvant therapy for ER+ premenopausal breast Ca
MC cystic mass in reproductive-age women
most prostate CA develops in which zone?
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
Tumor marker for endodermal sinus tumor, embryonal carcinoma
normal strict morphology required to bind to?
Chemo combo for advanced bladder CA
Call-Exner bodies, Inhibin+
Adnexal mass in reproductive age female, first r/o?
malignant germ cell tumor: beta HCG
6 months w/o period
MC site of mets in metastatic breast cancer
Hallmark pathological finding of granulosa cell tumots
oligohydramnios and 'key hole' sign
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
Worst SE of Magnesium sulfate
Tx of choice for vaginal atrophy
trophoblastic proliferation, fetus or fetal tissue present
Tumor marker for dysgerminoma
Most common estrogenic ovarian tumor
Type of incontinence: neurogenic dysfunction
Tumor marker of seminoma
Progestin in BCPs derived from spironolactone
beta 2 receptors cause uterine ?
Lab value inc if patient is not making sperm
% of simple atypical hyperplasia that progressed to cancer
pain with sex
Class of Rx for urge incontinence to dec contractility
Any condition irritating the periotoneal lining inc which marker?
Removal of breast, pec minor and axillary lymph node
measure seminal vesciles - dilated due to?
hormone causing ovulation
MC renal tumor
Kidney CA stage T4, invades
Permanent cessation of menses x1yr w/ high FSH, low E2
medical tx: urge incontinence
Most important prognostic factor in breast Ca
MC site of involvement in endometriosis
MC group of aneuploidy in spont ab
Induce fetal lung maturity - give mom ?
proliferation marker in endometrial cycle
Prevent sz in preeclampsia
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
HTN dx in first 20 weeks of pregnancy
pau d' orange, cancer cells in dermal lymphatics
Higher percent of free PSA (25%+)
Breast duct/lobule cells that produce milk
Rx w/ SE: endometrial polyps
dilatation of ducts, inspissated (thick) secretions

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Created Nov 17, 2012ReportNominate