8b GUG

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QuestionAnswerNotes
Lady on tamoxifen w/ post-menopausal bleeding - next step?
HPV: Degrades p53 in the host cell
trophoblastic proliferation, fetus or fetal tissue present
screening for nonpalpable breast masses
ovarian neoplasm w/ 3 germinal layers
Given to prevent CW recurrence at mastectomy site
Thin, long unilocular mass, associated with period
Converts androgens to estrogen
Signet ring cells in ovary = ?
Main mode of spread of ovarian cancer
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
Chromosome 17, 85% lifetime breast Ca risk
Varicocele finding on U/S
malignant germ cell tumor: AFP
Colposcopy: cells w/ inc collagen turn white w/ ?
Adnexal mass in reproductive age female, first r/o?
Special type breast CA, high grade but good prognosis
Induce fetal lung maturity - give mom ?
CA most strongly associated w/ obesity
MCC abnml uterine bleeding in postmenopausal
Tx: antagonist in breast; agonist in endometrium
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
HTN after 20 wk gestation assoc w/ proteinuria
acute infection w/ obstruction -1st step?
Appendix epididymis remnant of ?
MC ovarian germ cell tumor
MC group of aneuploidy in spont ab
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
BPH Rx SE: orthostasis, dizziness, fall risk
Endometrium that has been hormonally influenced by pregnancy
MC breast carcinoma in situ
Type of incontinence: neurogenic dysfunction
Progestin in BCPs derived from spironolactone
MCC abnml uterine bleeding in adolescence
Tumor marker of seminoma
Lowest contraceptive failure rates
Syndrome: AD w/ 85% penetrance, BRCA
MC renal tumor
6 months w/o period
Hallmark pathological finding of granulosa cell tumots
Condition during lactation, mimics inflammatory breast cancer
first line hormonal therapy of metastatic breast Ca in premenopausal
Targeted therapy for ER+ breast CA
MC cystic mass in reproductive-age women
Assoc w/ uterine hyperplasia/CA in postmenopausal women
male contraceptive = exogenous hormone?
umbilical cord inserts into the fetal membranes
Malignant tumor of admixed proliferating trophoblasts, no villi
L1 proteins from HPV strains self-assemble into non-infectious units called?
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
MC histology of cervival CA
Marker WT-1
best imaging modality for tubal infertility
Chromosome of BRCA-2
sudden huge increase in PSA likely due to?
MC histiological subtype of endometrial CA
MC method of contraception
HTN after 20 wk w/o proteinuria
MC type of endometrial carcinoma
Rx: adjuvant therapy for postmenopausal breast Ca
MC tumor of myometrium
Tx: tubal factor infertility
Abnormally deep implantation onto the myometrium
MC location of transitional cell cancer
Other name for ovarian fibroma
Antigen that lyses seminal coagulum
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
Why is stage I breast Ca 10-year survival only 75%?
'blue dot' sign and pain related to inflammation
Molecular? Type I, simple - complex hyperplasia
Tx symptomatic bone mets (prostate CA)
Tumor marker for endodermal sinus tumor, embryonal carcinoma
QuestionAnswerNotes
trophoblastic proliferation, cystic villi, no fetal tissue
MC site to endometriosis
antepartum hemorrhage after 20 wks
MC testicular tumor
Still a cause of maternal and fetal death
Molecular? Type I, proliferative - simple hyperplasia
Call-Exner bodies, Inhibin+
IUD c/i in Wilson's disease
intraurethral Rx for ED
Rx SE: PSA drops in half, ED, loss of libido
#1 killer of neonates
testicular torsion perinatal only
implantation into cornu of uterus or lower uterine segment
Origin of 90% ovarian cancers (aka MC form)
Targeted therapy for HER2+ breast CA
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
first line hormonal therapy of metastatic breast Ca in postmeno
Higher percent of free PSA (25%+)
Kidney CA stage T4, invades
Permanent cessation of menses x1yr w/ high FSH, low E2
Amniotic Fluid Index >90th %ile
Most common estrogenic ovarian tumor
Perimenopausal uterine bleeding, first step?
Tumor from dense fibroconnective tissue of the breast
oligohydramnios and 'key hole' sign
Rx: adjuvant therapy for ER+ premenopausal breast Ca
Dz: epidermis of nipple contains tumor cells
division of ovum after 13 days
Bilateral ovarian mets w/ signet ring
MCC Epididymal Orchitis in young men
low value w/ anovulation: failure to centrally stimulate follicular growth
Flow of urine in retrograde fashion (to kidney) w/ voiding
Tumor marker of stromal cell tumors
Long acting Rx for ED
MC infiltrating breast Ca
presence of endometrial glands in uterine myometrium
Stage: detected from elevated PSA alone, normal DRE & TRUS
highest risk of prostate CA starting at what age?
Class of Rx for urge incontinence to dec contractility
measure seminal vesciles - dilated due to?
medical tx: urge incontinence
HTN dx in first 20 weeks of pregnancy
Breast duct/lobule cells that produce milk
Appendix testes remnant of ?
% of simple atypical hyperplasia that progressed to cancer
Mech: Change in transport speed of the ovum
MC gynecologic CA
Sv consequence of anovulatory cycle
MC ovarian tumor (and cancer)
Type of cancer after tx for mediastinal mass in college age woman
elevated seminal leukocyte count aka?
e of incontinence: unstable bladder
abnormal dev of chorionic villi in pregnancy can become?
Grading scheme for prostatic adenocarcinoma
Major SE of contraceptive implants
MC neoplasm in young men
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
Type II endometrial carcinoma assoc w/ ?
Tx: stimulate ovary - induce endogenous FSH release
Most important reason fertility dec w/ female age is increasing ?
hypogonadotropic hypogonadism and anosmia
pain with sex
'powder burn' lesions
Rx w/ SE: endometrial polyps
Endometrial glands/stroma implanted outside uterine cavity/walls
exogenous testosterone leads to ? type of kidney stones
MC trisomy in spontaneous abortion
normal strict morphology required to bind to?
MC composition of kidney stones
MC benign growth in breast
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
% of complex hyperplasia that progressed to cancer
QuestionAnswerNotes
bleeding but os is open or closed, but still viable pregnancy
Infection causing bladder CA
Chemo combo for advanced bladder CA
2nd most common primary site of mets to ovary
HPV: Binds rB allowing for cell immortalization
Most important prognostic factor in breast Ca
Removal of breast, pec minor and axillary lymph node
20-25% of adnexal masses, dx b/t age 10-30yo
Mutation in mucinous ovarian tumors
hormone causing ovulation
beta 2 receptors cause uterine ?
Tumor marker for choriocarcinoma, embryonal carcinoma
intraabdominal pregnancy, later found in a 60yo woman
Type of incontinence: outlet obstruction
Cells that convert adrenal steroids to estrone
dilatation of ducts, inspissated (thick) secretions
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
mech of finasteride, dutasteride
% of simple hyperplasia that progressed to cancer
twins share chorion but one gets more blood flow
Proper name for 'chocolate cyst'
Bladder cancer sx in 85% of cases
Any condition irritating the periotoneal lining inc which marker?
Sperm with DNA damage is assoc w/ ?
Mutation assoc w/ high grade endometrioid tumors
postmenopausal, complex hyperplasia w/ atypia - tx?
Tx of choice for vaginal atrophy
MC site of mets in metastatic breast cancer
MCC male infertility in the world
Zone sampled in pap smear and biopsy
Composition of staghorn stone
hormonal therapy of metastatic breast Ca causing chemical castration
Worst SE of Magnesium sulfate
Tx PUV: Incise valve to damage leaflet
MC aneuploidy in abortuses
% of complex atypical hyperplasia that progressed to cancer
Ovarian tumor w/ KRAS and BRAF mutations
MCC UTO in male children
tx: stress urinary incontinence that inc sphincter tone
proliferation marker in endometrial cycle
Oral contraceptive in breastfeeding woman
MC site of ectopic pregnant
Renal CA assoc w/ Von Hippel-Lindau
MC site of involvement in endometriosis
MCC of amenorrhea (after pregnancy)
Lab value inc if patient is not making sperm
Prevent sz in preeclampsia
MC gynecological CA worldwide
How to stage endometrial CA
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
reflex test to triage ASCUS pap smear in women > 21
Most important RF for uterine CA
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
pau d' orange, cancer cells in dermal lymphatics
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
Papillary projections surrounded by Schiller-Duval bodies
MC STI
Uterine size discrepant from dates
malignant germ cell tumor: beta HCG
breast path - clown face
HRT: w/ uterus, need estrogen and ?
class of Rx for urge incontinence to tighten outlet
monoclonal ab to HER-2 neu
most prostate CA develops in which zone?
Best available protection against STIs
MC Tx of superficial bladder cancer
C/I for anticholinergic therapy
If surgery unavailable for testicular torson, reduce by twisting?
Penile CA 0% in men who are ?
MCC testis CA >50yo
Tumor marker for dysgerminoma

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Created Nov 17, 2012ReportNominate
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