8b GUG

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Can you name the 8b GUG?

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medical tx: urge incontinence
Lowest contraceptive failure rates
monoclonal ab to HER-2 neu
measure seminal vesciles - dilated due to?
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
Colposcopy: cells w/ inc collagen turn white w/ ?
BPH Rx SE: orthostasis, dizziness, fall risk
e of incontinence: unstable bladder
'powder burn' lesions
umbilical cord inserts into the fetal membranes
% of complex hyperplasia that progressed to cancer
Tx: stimulate ovary - induce endogenous FSH release
Why is stage I breast Ca 10-year survival only 75%?
Higher percent of free PSA (25%+)
Targeted therapy for ER+ breast CA
Most important RF for uterine CA
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
MCC abnml uterine bleeding in adolescence
Penile CA 0% in men who are ?
Renal CA assoc w/ Von Hippel-Lindau
HTN after 20 wk gestation assoc w/ proteinuria
HPV: Degrades p53 in the host cell
trophoblastic proliferation, cystic villi, no fetal tissue
% of simple atypical hyperplasia that progressed to cancer
Progestin in BCPs derived from spironolactone
MCC Epididymal Orchitis in young men
Antigen that lyses seminal coagulum
Type of incontinence: outlet obstruction
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
Assoc w/ uterine hyperplasia/CA in postmenopausal women
malignant germ cell tumor: AFP
MCC testis CA >50yo
MC aneuploidy in abortuses
MC breast carcinoma in situ
most prostate CA develops in which zone?
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
antepartum hemorrhage after 20 wks
Tumor marker for endodermal sinus tumor, embryonal carcinoma
MC benign growth in breast
Varicocele finding on U/S
#1 killer of neonates
Call-Exner bodies, Inhibin+
presence of endometrial glands in uterine myometrium
Appendix epididymis remnant of ?
proliferation marker in endometrial cycle
Cells that convert adrenal steroids to estrone
Molecular? Type I, proliferative - simple hyperplasia
MC site of mets in metastatic breast cancer
normal strict morphology required to bind to?
Chromosome 17, 85% lifetime breast Ca risk
Long acting Rx for ED
bleeding but os is open or closed, but still viable pregnancy
MC ovarian germ cell tumor
MC ovarian tumor (and cancer)
Tx of choice for vaginal atrophy
ovarian neoplasm w/ 3 germinal layers
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
HPV: Binds rB allowing for cell immortalization
Papillary projections surrounded by Schiller-Duval bodies
MC testicular tumor
oligohydramnios and 'key hole' sign
Most common estrogenic ovarian tumor
Tumor marker of stromal cell tumors
tx: stress urinary incontinence that inc sphincter tone
Type II endometrial carcinoma assoc w/ ?
MC histology of cervival CA
Lab value inc if patient is not making sperm
% of simple hyperplasia that progressed to cancer
elevated seminal leukocyte count aka?
first line hormonal therapy of metastatic breast Ca in premenopausal
Kidney CA stage T4, invades
MC infiltrating breast Ca
Class of Rx for urge incontinence to dec contractility
Malignant tumor of admixed proliferating trophoblasts, no villi
abnormal dev of chorionic villi in pregnancy can become?
trophoblastic proliferation, fetus or fetal tissue present
twins share chorion but one gets more blood flow
MC tumor of myometrium
Flow of urine in retrograde fashion (to kidney) w/ voiding
Chromosome of BRCA-2
% of complex atypical hyperplasia that progressed to cancer
low value w/ anovulation: failure to centrally stimulate follicular growth
Tumor marker of seminoma
highest risk of prostate CA starting at what age?
MC gynecologic CA
Prevent sz in preeclampsia
Rx SE: PSA drops in half, ED, loss of libido
Given to prevent CW recurrence at mastectomy site
Endometrial glands/stroma implanted outside uterine cavity/walls
Rx: adjuvant therapy for postmenopausal breast Ca
MC renal tumor
dilatation of ducts, inspissated (thick) secretions
beta 2 receptors cause uterine ?
Worst SE of Magnesium sulfate
pain with sex
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
Mutation in mucinous ovarian tumors
Best available protection against STIs
Tumor from dense fibroconnective tissue of the breast
Tumor marker for dysgerminoma
MC composition of kidney stones
HRT: w/ uterus, need estrogen and ?
pau d' orange, cancer cells in dermal lymphatics
Marker WT-1
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
Proper name for 'chocolate cyst'
Converts androgens to estrogen
screening for nonpalpable breast masses
Most important prognostic factor in breast Ca
MC location of transitional cell cancer
Mech: Change in transport speed of the ovum
MC Tx of superficial bladder cancer
Most important reason fertility dec w/ female age is increasing ?
MC method of contraception
Permanent cessation of menses x1yr w/ high FSH, low E2
MC histiological subtype of endometrial CA
Bilateral ovarian mets w/ signet ring
Condition during lactation, mimics inflammatory breast cancer
Tx: antagonist in breast; agonist in endometrium
Stage: detected from elevated PSA alone, normal DRE & TRUS
Type of cancer after tx for mediastinal mass in college age woman
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
Sperm with DNA damage is assoc w/ ?
MCC abnml uterine bleeding in postmenopausal
MC type of endometrial carcinoma
Composition of staghorn stone
male contraceptive = exogenous hormone?
MCC of amenorrhea (after pregnancy)
HTN after 20 wk w/o proteinuria
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
class of Rx for urge incontinence to tighten outlet
first line hormonal therapy of metastatic breast Ca in postmeno
Breast duct/lobule cells that produce milk
Uterine size discrepant from dates
Tx symptomatic bone mets (prostate CA)
Other name for ovarian fibroma
L1 proteins from HPV strains self-assemble into non-infectious units called?
Oral contraceptive in breastfeeding woman
Lady on tamoxifen w/ post-menopausal bleeding - next step?
Bladder cancer sx in 85% of cases
MC group of aneuploidy in spont ab
Sv consequence of anovulatory cycle
hormone causing ovulation
MCC UTO in male children
acute infection w/ obstruction -1st step?
Dz: epidermis of nipple contains tumor cells
Tumor marker for choriocarcinoma, embryonal carcinoma
MCC male infertility in the world
division of ovum after 13 days
20-25% of adnexal masses, dx b/t age 10-30yo
Syndrome: AD w/ 85% penetrance, BRCA
MC site of ectopic pregnant
intraabdominal pregnancy, later found in a 60yo woman
Type of incontinence: neurogenic dysfunction
Molecular? Type I, simple - complex hyperplasia
Induce fetal lung maturity - give mom ?
2nd most common primary site of mets to ovary
hypogonadotropic hypogonadism and anosmia
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
Hallmark pathological finding of granulosa cell tumots
sudden huge increase in PSA likely due to?
Rx: adjuvant therapy for ER+ premenopausal breast Ca
Chemo combo for advanced bladder CA
malignant germ cell tumor: beta HCG
intraurethral Rx for ED
Endometrium that has been hormonally influenced by pregnancy
MC site to endometriosis
testicular torsion perinatal only
Targeted therapy for HER2+ breast CA
'blue dot' sign and pain related to inflammation
MC trisomy in spontaneous abortion
IUD c/i in Wilson's disease
Rx w/ SE: endometrial polyps
Mutation assoc w/ high grade endometrioid tumors
MC gynecological CA worldwide
postmenopausal, complex hyperplasia w/ atypia - tx?
reflex test to triage ASCUS pap smear in women > 21
Adnexal mass in reproductive age female, first r/o?
If surgery unavailable for testicular torson, reduce by twisting?
Special type breast CA, high grade but good prognosis
Main mode of spread of ovarian cancer
Origin of 90% ovarian cancers (aka MC form)
Ovarian tumor w/ KRAS and BRAF mutations
Major SE of contraceptive implants
Grading scheme for prostatic adenocarcinoma
breast path - clown face
Tx PUV: Incise valve to damage leaflet
mech of finasteride, dutasteride
hormonal therapy of metastatic breast Ca causing chemical castration
exogenous testosterone leads to ? type of kidney stones
Perimenopausal uterine bleeding, first step?
MC cystic mass in reproductive-age women
Signet ring cells in ovary = ?
Removal of breast, pec minor and axillary lymph node
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
Thin, long unilocular mass, associated with period
Zone sampled in pap smear and biopsy
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
MC neoplasm in young men
Tx: tubal factor infertility
best imaging modality for tubal infertility
Infection causing bladder CA
CA most strongly associated w/ obesity
Appendix testes remnant of ?
HTN dx in first 20 weeks of pregnancy
MC site of involvement in endometriosis
Amniotic Fluid Index >90th %ile
Still a cause of maternal and fetal death
C/I for anticholinergic therapy
6 months w/o period
Any condition irritating the periotoneal lining inc which marker?
implantation into cornu of uterus or lower uterine segment
How to stage endometrial CA
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
Abnormally deep implantation onto the myometrium

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