8b GUG

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QuestionAnswerNotes
HTN after 20 wk w/o proteinuria
MC site to endometriosis
Higher percent of free PSA (25%+)
HRT: w/ uterus, need estrogen and ?
Call-Exner bodies, Inhibin+
Infection causing bladder CA
class of Rx for urge incontinence to tighten outlet
Tumor marker for dysgerminoma
presence of endometrial glands in uterine myometrium
twins share chorion but one gets more blood flow
testicular torsion perinatal only
Given to prevent CW recurrence at mastectomy site
Penile CA 0% in men who are ?
Kidney CA stage T4, invades
MC neoplasm in young men
MCC UTO in male children
Chromosome of BRCA-2
Mutation in mucinous ovarian tumors
malignant germ cell tumor: beta HCG
Perimenopausal uterine bleeding, first step?
Type II endometrial carcinoma assoc w/ ?
Adnexal mass in reproductive age female, first r/o?
MCC abnml uterine bleeding in adolescence
MC gynecologic CA
Cells that convert adrenal steroids to estrone
MC benign growth in breast
acute infection w/ obstruction -1st step?
normal strict morphology required to bind to?
MC STI
Malignant tumor of admixed proliferating trophoblasts, no villi
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
abnormal dev of chorionic villi in pregnancy can become?
Targeted therapy for ER+ breast CA
'blue dot' sign and pain related to inflammation
elevated seminal leukocyte count aka?
MC site of ectopic pregnant
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
Type of incontinence: neurogenic dysfunction
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
Bladder cancer sx in 85% of cases
trophoblastic proliferation, fetus or fetal tissue present
reflex test to triage ASCUS pap smear in women > 21
Stage: detected from elevated PSA alone, normal DRE & TRUS
Tumor from dense fibroconnective tissue of the breast
MCC male infertility in the world
Sv consequence of anovulatory cycle
Major SE of contraceptive implants
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
measure seminal vesciles - dilated due to?
Tx: tubal factor infertility
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
Tumor marker of seminoma
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
breast path - clown face
Removal of breast, pec minor and axillary lymph node
MC ovarian germ cell tumor
Permanent cessation of menses x1yr w/ high FSH, low E2
MCC Epididymal Orchitis in young men
Induce fetal lung maturity - give mom ?
CA most strongly associated w/ obesity
Hallmark pathological finding of granulosa cell tumots
umbilical cord inserts into the fetal membranes
Tx PUV: Incise valve to damage leaflet
2nd most common primary site of mets to ovary
intraurethral Rx for ED
Tx: stimulate ovary - induce endogenous FSH release
Tx: antagonist in breast; agonist in endometrium
Class of Rx for urge incontinence to dec contractility
beta 2 receptors cause uterine ?
postmenopausal, complex hyperplasia w/ atypia - tx?
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
MC testicular tumor
QuestionAnswerNotes
Why is stage I breast Ca 10-year survival only 75%?
MC ovarian tumor (and cancer)
Molecular? Type I, proliferative - simple hyperplasia
L1 proteins from HPV strains self-assemble into non-infectious units called?
Progestin in BCPs derived from spironolactone
male contraceptive = exogenous hormone?
Other name for ovarian fibroma
MCC testis CA >50yo
Any condition irritating the periotoneal lining inc which marker?
Long acting Rx for ED
Varicocele finding on U/S
highest risk of prostate CA starting at what age?
Converts androgens to estrogen
% of complex atypical hyperplasia that progressed to cancer
MC gynecological CA worldwide
Origin of 90% ovarian cancers (aka MC form)
MC breast carcinoma in situ
Still a cause of maternal and fetal death
Ovarian tumor w/ KRAS and BRAF mutations
monoclonal ab to HER-2 neu
'powder burn' lesions
Tx of choice for vaginal atrophy
Worst SE of Magnesium sulfate
tx: stress urinary incontinence that inc sphincter tone
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
Mutation assoc w/ high grade endometrioid tumors
MC site of mets in metastatic breast cancer
pain with sex
intraabdominal pregnancy, later found in a 60yo woman
Special type breast CA, high grade but good prognosis
Endometrial glands/stroma implanted outside uterine cavity/walls
Best available protection against STIs
antepartum hemorrhage after 20 wks
HPV: Binds rB allowing for cell immortalization
C/I for anticholinergic therapy
Targeted therapy for HER2+ breast CA
HPV: Degrades p53 in the host cell
% of complex hyperplasia that progressed to cancer
MC histology of cervival CA
e of incontinence: unstable bladder
If surgery unavailable for testicular torson, reduce by twisting?
Grading scheme for prostatic adenocarcinoma
MC infiltrating breast Ca
first line hormonal therapy of metastatic breast Ca in postmeno
MC location of transitional cell cancer
MCC of amenorrhea (after pregnancy)
medical tx: urge incontinence
Rx: adjuvant therapy for postmenopausal breast Ca
Lowest contraceptive failure rates
bleeding but os is open or closed, but still viable pregnancy
division of ovum after 13 days
trophoblastic proliferation, cystic villi, no fetal tissue
Most important RF for uterine CA
20-25% of adnexal masses, dx b/t age 10-30yo
HTN dx in first 20 weeks of pregnancy
sudden huge increase in PSA likely due to?
mech of finasteride, dutasteride
Tx symptomatic bone mets (prostate CA)
Chemo combo for advanced bladder CA
Amniotic Fluid Index >90th %ile
Uterine size discrepant from dates
Main mode of spread of ovarian cancer
Proper name for 'chocolate cyst'
Most important reason fertility dec w/ female age is increasing ?
MC cystic mass in reproductive-age women
% of simple atypical hyperplasia that progressed to cancer
Chromosome 17, 85% lifetime breast Ca risk
best imaging modality for tubal infertility
MC site of involvement in endometriosis
6 months w/o period
Composition of staghorn stone
Signet ring cells in ovary = ?
QuestionAnswerNotes
Rx SE: PSA drops in half, ED, loss of libido
Colposcopy: cells w/ inc collagen turn white w/ ?
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
Marker WT-1
Bilateral ovarian mets w/ signet ring
Condition during lactation, mimics inflammatory breast cancer
MC composition of kidney stones
Prevent sz in preeclampsia
first line hormonal therapy of metastatic breast Ca in premenopausal
Appendix testes remnant of ?
Endometrium that has been hormonally influenced by pregnancy
Assoc w/ uterine hyperplasia/CA in postmenopausal women
most prostate CA develops in which zone?
oligohydramnios and 'key hole' sign
MC renal tumor
MC group of aneuploidy in spont ab
Lab value inc if patient is not making sperm
Abnormally deep implantation onto the myometrium
malignant germ cell tumor: AFP
hormone causing ovulation
Syndrome: AD w/ 85% penetrance, BRCA
Papillary projections surrounded by Schiller-Duval bodies
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
pau d' orange, cancer cells in dermal lymphatics
Type of incontinence: outlet obstruction
MC Tx of superficial bladder cancer
low value w/ anovulation: failure to centrally stimulate follicular growth
MC histiological subtype of endometrial CA
Antigen that lyses seminal coagulum
Rx w/ SE: endometrial polyps
implantation into cornu of uterus or lower uterine segment
Appendix epididymis remnant of ?
Flow of urine in retrograde fashion (to kidney) w/ voiding
Most important prognostic factor in breast Ca
Lady on tamoxifen w/ post-menopausal bleeding - next step?
Zone sampled in pap smear and biopsy
How to stage endometrial CA
MCC abnml uterine bleeding in postmenopausal
Most common estrogenic ovarian tumor
exogenous testosterone leads to ? type of kidney stones
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
MC tumor of myometrium
Tumor marker for endodermal sinus tumor, embryonal carcinoma
ovarian neoplasm w/ 3 germinal layers
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
Tumor marker for choriocarcinoma, embryonal carcinoma
MC type of endometrial carcinoma
Breast duct/lobule cells that produce milk
Renal CA assoc w/ Von Hippel-Lindau
Thin, long unilocular mass, associated with period
Mech: Change in transport speed of the ovum
#1 killer of neonates
Sperm with DNA damage is assoc w/ ?
Molecular? Type I, simple - complex hyperplasia
Tumor marker of stromal cell tumors
proliferation marker in endometrial cycle
hypogonadotropic hypogonadism and anosmia
dilatation of ducts, inspissated (thick) secretions
IUD c/i in Wilson's disease
screening for nonpalpable breast masses
MC aneuploidy in abortuses
hormonal therapy of metastatic breast Ca causing chemical castration
Dz: epidermis of nipple contains tumor cells
% of simple hyperplasia that progressed to cancer
Oral contraceptive in breastfeeding woman
Type of cancer after tx for mediastinal mass in college age woman
HTN after 20 wk gestation assoc w/ proteinuria
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
MC trisomy in spontaneous abortion
BPH Rx SE: orthostasis, dizziness, fall risk
Rx: adjuvant therapy for ER+ premenopausal breast Ca
MC method of contraception

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