8b GUG

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MC gynecological CA worldwide
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
medical tx: urge incontinence
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
Tumor marker for dysgerminoma
Oral contraceptive in breastfeeding woman
MC testicular tumor
Perimenopausal uterine bleeding, first step?
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
Tumor marker for endodermal sinus tumor, embryonal carcinoma
Proper name for 'chocolate cyst'
intraabdominal pregnancy, later found in a 60yo woman
6 months w/o period
Chemo combo for advanced bladder CA
Most important prognostic factor in breast Ca
Mutation assoc w/ high grade endometrioid tumors
Uterine size discrepant from dates
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
MC tumor of myometrium
bleeding but os is open or closed, but still viable pregnancy
e of incontinence: unstable bladder
Renal CA assoc w/ Von Hippel-Lindau
Abnormally deep implantation onto the myometrium
trophoblastic proliferation, cystic villi, no fetal tissue
L1 proteins from HPV strains self-assemble into non-infectious units called?
Breast duct/lobule cells that produce milk
oligohydramnios and 'key hole' sign
Malignant tumor of admixed proliferating trophoblasts, no villi
proliferation marker in endometrial cycle
Kidney CA stage T4, invades
BPH Rx SE: orthostasis, dizziness, fall risk
tx: stress urinary incontinence that inc sphincter tone
Rx: adjuvant therapy for ER+ premenopausal breast Ca
Most important reason fertility dec w/ female age is increasing ?
MCC UTO in male children
MC site of ectopic pregnant
How to stage endometrial CA
measure seminal vesciles - dilated due to?
HPV: Binds rB allowing for cell immortalization
MC site of involvement in endometriosis
Varicocele finding on U/S
HTN after 20 wk w/o proteinuria
Dz: epidermis of nipple contains tumor cells
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
% of simple hyperplasia that progressed to cancer
Progestin in BCPs derived from spironolactone
Syndrome: AD w/ 85% penetrance, BRCA
MC composition of kidney stones
first line hormonal therapy of metastatic breast Ca in premenopausal
reflex test to triage ASCUS pap smear in women > 21
MCC abnml uterine bleeding in adolescence
Chromosome 17, 85% lifetime breast Ca risk
Worst SE of Magnesium sulfate
dilatation of ducts, inspissated (thick) secretions
Converts androgens to estrogen
Call-Exner bodies, Inhibin+
Given to prevent CW recurrence at mastectomy site
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
MC ovarian germ cell tumor
first line hormonal therapy of metastatic breast Ca in postmeno
MC breast carcinoma in situ
Zone sampled in pap smear and biopsy
antepartum hemorrhage after 20 wks
Ovarian tumor w/ KRAS and BRAF mutations
Other name for ovarian fibroma
Endometrial glands/stroma implanted outside uterine cavity/walls
elevated seminal leukocyte count aka?
Rx: adjuvant therapy for postmenopausal breast Ca
Lab value inc if patient is not making sperm
HTN after 20 wk gestation assoc w/ proteinuria
Appendix epididymis remnant of ?
MC type of endometrial carcinoma
Type of incontinence: outlet obstruction
Special type breast CA, high grade but good prognosis
MCC male infertility in the world
Origin of 90% ovarian cancers (aka MC form)
Most common estrogenic ovarian tumor
% of simple atypical hyperplasia that progressed to cancer
MCC testis CA >50yo
best imaging modality for tubal infertility
MC aneuploidy in abortuses
Endometrium that has been hormonally influenced by pregnancy
Amniotic Fluid Index >90th %ile
2nd most common primary site of mets to ovary
HPV: Degrades p53 in the host cell
MCC of amenorrhea (after pregnancy)
Major SE of contraceptive implants
postmenopausal, complex hyperplasia w/ atypia - tx?
ovarian neoplasm w/ 3 germinal layers
Rx SE: PSA drops in half, ED, loss of libido
HTN dx in first 20 weeks of pregnancy
presence of endometrial glands in uterine myometrium
% of complex atypical hyperplasia that progressed to cancer
Tumor from dense fibroconnective tissue of the breast
MC histology of cervival CA
hypogonadotropic hypogonadism and anosmia
breast path - clown face
Composition of staghorn stone
Tx of choice for vaginal atrophy
Adnexal mass in reproductive age female, first r/o?
Sperm with DNA damage is assoc w/ ?
MC histiological subtype of endometrial CA
Sv consequence of anovulatory cycle
most prostate CA develops in which zone?
intraurethral Rx for ED
MCC Epididymal Orchitis in young men
division of ovum after 13 days
Still a cause of maternal and fetal death
Targeted therapy for ER+ breast CA
Tumor marker for choriocarcinoma, embryonal carcinoma
highest risk of prostate CA starting at what age?
C/I for anticholinergic therapy
MC renal tumor
Permanent cessation of menses x1yr w/ high FSH, low E2
MC cystic mass in reproductive-age women
pain with sex
Tx: tubal factor infertility
Marker WT-1
MC site of mets in metastatic breast cancer
MC location of transitional cell cancer
Stage: detected from elevated PSA alone, normal DRE & TRUS
MC benign growth in breast
MC neoplasm in young men
abnormal dev of chorionic villi in pregnancy can become?
Rx w/ SE: endometrial polyps
normal strict morphology required to bind to?
male contraceptive = exogenous hormone?
screening for nonpalpable breast masses
MC gynecologic CA
'powder burn' lesions
Mech: Change in transport speed of the ovum
implantation into cornu of uterus or lower uterine segment
Papillary projections surrounded by Schiller-Duval bodies
MC method of contraception
Higher percent of free PSA (25%+)
Type of cancer after tx for mediastinal mass in college age woman
MC Tx of superficial bladder cancer
MC infiltrating breast Ca
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
If surgery unavailable for testicular torson, reduce by twisting?
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
Prevent sz in preeclampsia
Induce fetal lung maturity - give mom ?
malignant germ cell tumor: beta HCG
mech of finasteride, dutasteride
trophoblastic proliferation, fetus or fetal tissue present
Tumor marker of stromal cell tumors
Molecular? Type I, simple - complex hyperplasia
twins share chorion but one gets more blood flow
Penile CA 0% in men who are ?
Tumor marker of seminoma
Assoc w/ uterine hyperplasia/CA in postmenopausal women
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
Molecular? Type I, proliferative - simple hyperplasia
Colposcopy: cells w/ inc collagen turn white w/ ?
Long acting Rx for ED
Chromosome of BRCA-2
CA most strongly associated w/ obesity
MCC abnml uterine bleeding in postmenopausal
MC ovarian tumor (and cancer)
Any condition irritating the periotoneal lining inc which marker?
MC group of aneuploidy in spont ab
Thin, long unilocular mass, associated with period
Most important RF for uterine CA
Signet ring cells in ovary = ?
testicular torsion perinatal only
exogenous testosterone leads to ? type of kidney stones
#1 killer of neonates
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
hormone causing ovulation
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
pau d' orange, cancer cells in dermal lymphatics
beta 2 receptors cause uterine ?
Main mode of spread of ovarian cancer
MC site to endometriosis
HRT: w/ uterus, need estrogen and ?
Bladder cancer sx in 85% of cases
Type of incontinence: neurogenic dysfunction
low value w/ anovulation: failure to centrally stimulate follicular growth
Class of Rx for urge incontinence to dec contractility
Grading scheme for prostatic adenocarcinoma
Tx: stimulate ovary - induce endogenous FSH release
umbilical cord inserts into the fetal membranes
Cells that convert adrenal steroids to estrone
Removal of breast, pec minor and axillary lymph node
Hallmark pathological finding of granulosa cell tumots
MC trisomy in spontaneous abortion
malignant germ cell tumor: AFP
Tx PUV: Incise valve to damage leaflet
Best available protection against STIs
Type II endometrial carcinoma assoc w/ ?
Tx symptomatic bone mets (prostate CA)
hormonal therapy of metastatic breast Ca causing chemical castration
Targeted therapy for HER2+ breast CA
Flow of urine in retrograde fashion (to kidney) w/ voiding
monoclonal ab to HER-2 neu
Condition during lactation, mimics inflammatory breast cancer
20-25% of adnexal masses, dx b/t age 10-30yo
Why is stage I breast Ca 10-year survival only 75%?
IUD c/i in Wilson's disease
Mutation in mucinous ovarian tumors
% of complex hyperplasia that progressed to cancer
Bilateral ovarian mets w/ signet ring
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
Tx: antagonist in breast; agonist in endometrium
Lady on tamoxifen w/ post-menopausal bleeding - next step?
acute infection w/ obstruction -1st step?
Lowest contraceptive failure rates
'blue dot' sign and pain related to inflammation
Appendix testes remnant of ?
Infection causing bladder CA
sudden huge increase in PSA likely due to?
class of Rx for urge incontinence to tighten outlet
Antigen that lyses seminal coagulum

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Created Nov 17, 2012ReportNominate