8b GUG

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Can you name the 8b GUG?

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Oral contraceptive in breastfeeding woman
Major SE of contraceptive implants
Lowest contraceptive failure rates
Abnormally deep implantation onto the myometrium
HRT: w/ uterus, need estrogen and ?
medical tx: urge incontinence
'blue dot' sign and pain related to inflammation
intraurethral Rx for ED
twins share chorion but one gets more blood flow
Type II endometrial carcinoma assoc w/ ?
Converts androgens to estrogen
MCC abnml uterine bleeding in postmenopausal
6 months w/o period
MC type of endometrial carcinoma
Uterine size discrepant from dates
Tumor marker for endodermal sinus tumor, embryonal carcinoma
pau d' orange, cancer cells in dermal lymphatics
Tx symptomatic bone mets (prostate CA)
Rx: adjuvant therapy for postmenopausal breast Ca
dilatation of ducts, inspissated (thick) secretions
exogenous testosterone leads to ? type of kidney stones
Higher percent of free PSA (25%+)
MC aneuploidy in abortuses
HPV: Degrades p53 in the host cell
Permanent cessation of menses x1yr w/ high FSH, low E2
monoclonal ab to HER-2 neu
Why is stage I breast Ca 10-year survival only 75%?
highest risk of prostate CA starting at what age?
Renal CA assoc w/ Von Hippel-Lindau
elevated seminal leukocyte count aka?
MC gynecologic CA
MC gynecological CA worldwide
MC benign growth in breast
MCC abnml uterine bleeding in adolescence
MC site of mets in metastatic breast cancer
MC testicular tumor
Class of Rx for urge incontinence to dec contractility
Tumor marker of stromal cell tumors
Signet ring cells in ovary = ?
pain with sex
Malignant tumor of admixed proliferating trophoblasts, no villi
Most important prognostic factor in breast Ca
postmenopausal, complex hyperplasia w/ atypia - tx?
implantation into cornu of uterus or lower uterine segment
MC site of ectopic pregnant
Targeted therapy for HER2+ breast CA
normal strict morphology required to bind to?
MC tumor of myometrium
Antigen that lyses seminal coagulum
Colposcopy: cells w/ inc collagen turn white w/ ?
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
low value w/ anovulation: failure to centrally stimulate follicular growth
Tx: antagonist in breast; agonist in endometrium
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
20-25% of adnexal masses, dx b/t age 10-30yo
malignant germ cell tumor: beta HCG
Type of cancer after tx for mediastinal mass in college age woman
MC group of aneuploidy in spont ab
MC trisomy in spontaneous abortion
Cells that convert adrenal steroids to estrone
MC ovarian germ cell tumor
MC site to endometriosis
#1 killer of neonates
Main mode of spread of ovarian cancer
trophoblastic proliferation, cystic villi, no fetal tissue
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
'powder burn' lesions
MC neoplasm in young men
Most common estrogenic ovarian tumor
Long acting Rx for ED
2nd most common primary site of mets to ovary
CA most strongly associated w/ obesity
tx: stress urinary incontinence that inc sphincter tone
antepartum hemorrhage after 20 wks
HPV: Binds rB allowing for cell immortalization
Any condition irritating the periotoneal lining inc which marker?
Given to prevent CW recurrence at mastectomy site
Mech: Change in transport speed of the ovum
ovarian neoplasm w/ 3 germinal layers
If surgery unavailable for testicular torson, reduce by twisting?
% of simple hyperplasia that progressed to cancer
Type of incontinence: outlet obstruction
Appendix testes remnant of ?
Dz: epidermis of nipple contains tumor cells
MC cystic mass in reproductive-age women
MC method of contraception
HTN after 20 wk gestation assoc w/ proteinuria
MC ovarian tumor (and cancer)
Tumor marker for dysgerminoma
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
Most important reason fertility dec w/ female age is increasing ?
Hallmark pathological finding of granulosa cell tumots
Tx: tubal factor infertility
mech of finasteride, dutasteride
hormone causing ovulation
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
HTN after 20 wk w/o proteinuria
Kidney CA stage T4, invades
Amniotic Fluid Index >90th %ile
male contraceptive = exogenous hormone?
breast path - clown face
oligohydramnios and 'key hole' sign
MCC Epididymal Orchitis in young men
first line hormonal therapy of metastatic breast Ca in postmeno
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
proliferation marker in endometrial cycle
MC breast carcinoma in situ
Prevent sz in preeclampsia
Rx SE: PSA drops in half, ED, loss of libido
Varicocele finding on U/S
Rx w/ SE: endometrial polyps
hypogonadotropic hypogonadism and anosmia
Condition during lactation, mimics inflammatory breast cancer
Thin, long unilocular mass, associated with period
Tx of choice for vaginal atrophy
Stage: detected from elevated PSA alone, normal DRE & TRUS
How to stage endometrial CA
most prostate CA develops in which zone?
Endometrial glands/stroma implanted outside uterine cavity/walls
Tumor from dense fibroconnective tissue of the breast
Appendix epididymis remnant of ?
IUD c/i in Wilson's disease
intraabdominal pregnancy, later found in a 60yo woman
first line hormonal therapy of metastatic breast Ca in premenopausal
Composition of staghorn stone
Endometrium that has been hormonally influenced by pregnancy
Removal of breast, pec minor and axillary lymph node
measure seminal vesciles - dilated due to?
Breast duct/lobule cells that produce milk
Most important RF for uterine CA
Chromosome of BRCA-2
Assoc w/ uterine hyperplasia/CA in postmenopausal women
Marker WT-1
Perimenopausal uterine bleeding, first step?
Infection causing bladder CA
Bilateral ovarian mets w/ signet ring
Special type breast CA, high grade but good prognosis
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
Mutation assoc w/ high grade endometrioid tumors
umbilical cord inserts into the fetal membranes
Worst SE of Magnesium sulfate
Other name for ovarian fibroma
Ovarian tumor w/ KRAS and BRAF mutations
Tumor marker of seminoma
e of incontinence: unstable bladder
bleeding but os is open or closed, but still viable pregnancy
Mutation in mucinous ovarian tumors
MC Tx of superficial bladder cancer
% of simple atypical hyperplasia that progressed to cancer
Grading scheme for prostatic adenocarcinoma
MC location of transitional cell cancer
testicular torsion perinatal only
Tx PUV: Incise valve to damage leaflet
Molecular? Type I, simple - complex hyperplasia
Origin of 90% ovarian cancers (aka MC form)
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
% of complex hyperplasia that progressed to cancer
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
Proper name for 'chocolate cyst'
Targeted therapy for ER+ breast CA
Zone sampled in pap smear and biopsy
HTN dx in first 20 weeks of pregnancy
malignant germ cell tumor: AFP
division of ovum after 13 days
Syndrome: AD w/ 85% penetrance, BRCA
Flow of urine in retrograde fashion (to kidney) w/ voiding
Tumor marker for choriocarcinoma, embryonal carcinoma
Sv consequence of anovulatory cycle
presence of endometrial glands in uterine myometrium
Molecular? Type I, proliferative - simple hyperplasia
class of Rx for urge incontinence to tighten outlet
Lab value inc if patient is not making sperm
Best available protection against STIs
reflex test to triage ASCUS pap smear in women > 21
Rx: adjuvant therapy for ER+ premenopausal breast Ca
Tx: stimulate ovary - induce endogenous FSH release
screening for nonpalpable breast masses
MCC testis CA >50yo
best imaging modality for tubal infertility
MC histiological subtype of endometrial CA
% of complex atypical hyperplasia that progressed to cancer
MCC UTO in male children
MCC male infertility in the world
abnormal dev of chorionic villi in pregnancy can become?
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
trophoblastic proliferation, fetus or fetal tissue present
Lady on tamoxifen w/ post-menopausal bleeding - next step?
MC infiltrating breast Ca
MCC of amenorrhea (after pregnancy)
Chromosome 17, 85% lifetime breast Ca risk
Sperm with DNA damage is assoc w/ ?
Progestin in BCPs derived from spironolactone
acute infection w/ obstruction -1st step?
Induce fetal lung maturity - give mom ?
Chemo combo for advanced bladder CA
C/I for anticholinergic therapy
BPH Rx SE: orthostasis, dizziness, fall risk
L1 proteins from HPV strains self-assemble into non-infectious units called?
Call-Exner bodies, Inhibin+
Penile CA 0% in men who are ?
Still a cause of maternal and fetal death
Type of incontinence: neurogenic dysfunction
MC renal tumor
MC composition of kidney stones
sudden huge increase in PSA likely due to?
beta 2 receptors cause uterine ?
Adnexal mass in reproductive age female, first r/o?
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
Bladder cancer sx in 85% of cases
hormonal therapy of metastatic breast Ca causing chemical castration
MC site of involvement in endometriosis
Papillary projections surrounded by Schiller-Duval bodies
MC histology of cervival CA

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