8b GUG

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MCC Epididymal Orchitis in young men
Condition during lactation, mimics inflammatory breast cancer
Tx of choice for vaginal atrophy
Sv consequence of anovulatory cycle
2nd most common primary site of mets to ovary
Permanent cessation of menses x1yr w/ high FSH, low E2
% of complex atypical hyperplasia that progressed to cancer
proliferation marker in endometrial cycle
Type II endometrial carcinoma assoc w/ ?
Given to prevent CW recurrence at mastectomy site
Breast duct/lobule cells that produce milk
Tx: antagonist in breast; agonist in endometrium
exogenous testosterone leads to ? type of kidney stones
Best available protection against STIs
Most important prognostic factor in breast Ca
Molecular? Type I, simple - complex hyperplasia
Mutation in mucinous ovarian tumors
Stage: detected from elevated PSA alone, normal DRE & TRUS
tx: stress urinary incontinence that inc sphincter tone
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
MC neoplasm in young men
Tumor marker of seminoma
Uterine size discrepant from dates
Most common estrogenic ovarian tumor
MC histiological subtype of endometrial CA
male contraceptive = exogenous hormone?
MC ovarian tumor (and cancer)
Type of incontinence: neurogenic dysfunction
reflex test to triage ASCUS pap smear in women > 21
Mutation assoc w/ high grade endometrioid tumors
malignant germ cell tumor: beta HCG
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
Penile CA 0% in men who are ?
MC testicular tumor
Main mode of spread of ovarian cancer
Special type breast CA, high grade but good prognosis
Rx: adjuvant therapy for ER+ premenopausal breast Ca
Most important RF for uterine CA
MC cystic mass in reproductive-age women
Sperm with DNA damage is assoc w/ ?
Kidney CA stage T4, invades
Rx w/ SE: endometrial polyps
Converts androgens to estrogen
MC gynecological CA worldwide
HTN dx in first 20 weeks of pregnancy
Type of incontinence: outlet obstruction
HRT: w/ uterus, need estrogen and ?
IUD c/i in Wilson's disease
trophoblastic proliferation, cystic villi, no fetal tissue
Tumor marker for dysgerminoma
Bladder cancer sx in 85% of cases
abnormal dev of chorionic villi in pregnancy can become?
Mech: Change in transport speed of the ovum
MC ovarian germ cell tumor
elevated seminal leukocyte count aka?
Varicocele finding on U/S
Antigen that lyses seminal coagulum
HPV: Degrades p53 in the host cell
Zone sampled in pap smear and biopsy
twins share chorion but one gets more blood flow
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
normal strict morphology required to bind to?
MCC abnml uterine bleeding in postmenopausal
Tumor marker for endodermal sinus tumor, embryonal carcinoma
Tumor marker of stromal cell tumors
'powder burn' lesions
postmenopausal, complex hyperplasia w/ atypia - tx?
Chromosome of BRCA-2
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
Still a cause of maternal and fetal death
first line hormonal therapy of metastatic breast Ca in postmeno
Flow of urine in retrograde fashion (to kidney) w/ voiding
Abnormally deep implantation onto the myometrium
MC type of endometrial carcinoma
Amniotic Fluid Index >90th %ile
Why is stage I breast Ca 10-year survival only 75%?
MC aneuploidy in abortuses
Malignant tumor of admixed proliferating trophoblasts, no villi
MC renal tumor
Targeted therapy for HER2+ breast CA
Chemo combo for advanced bladder CA
Class of Rx for urge incontinence to dec contractility
malignant germ cell tumor: AFP
MC gynecologic CA
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
Rx SE: PSA drops in half, ED, loss of libido
MC histology of cervival CA
Higher percent of free PSA (25%+)
Cells that convert adrenal steroids to estrone
most prostate CA develops in which zone?
MCC abnml uterine bleeding in adolescence
20-25% of adnexal masses, dx b/t age 10-30yo
Molecular? Type I, proliferative - simple hyperplasia
mech of finasteride, dutasteride
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
Dz: epidermis of nipple contains tumor cells
MC trisomy in spontaneous abortion
measure seminal vesciles - dilated due to?
HTN after 20 wk gestation assoc w/ proteinuria
Thin, long unilocular mass, associated with period
pau d' orange, cancer cells in dermal lymphatics
% of simple atypical hyperplasia that progressed to cancer
pain with sex
class of Rx for urge incontinence to tighten outlet
Syndrome: AD w/ 85% penetrance, BRCA
Any condition irritating the periotoneal lining inc which marker?
MC breast carcinoma in situ
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
MCC of amenorrhea (after pregnancy)
trophoblastic proliferation, fetus or fetal tissue present
MC composition of kidney stones
sudden huge increase in PSA likely due to?
#1 killer of neonates
Long acting Rx for ED
implantation into cornu of uterus or lower uterine segment
Appendix testes remnant of ?
CA most strongly associated w/ obesity
How to stage endometrial CA
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
Signet ring cells in ovary = ?
MCC UTO in male children
Most important reason fertility dec w/ female age is increasing ?
Type of cancer after tx for mediastinal mass in college age woman
Composition of staghorn stone
6 months w/o period
Chromosome 17, 85% lifetime breast Ca risk
beta 2 receptors cause uterine ?
MC tumor of myometrium
Proper name for 'chocolate cyst'
MCC male infertility in the world
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
MC site to endometriosis
% of simple hyperplasia that progressed to cancer
MC method of contraception
Bilateral ovarian mets w/ signet ring
Tx: stimulate ovary - induce endogenous FSH release
acute infection w/ obstruction -1st step?
MC site of ectopic pregnant
highest risk of prostate CA starting at what age?
Targeted therapy for ER+ breast CA
BPH Rx SE: orthostasis, dizziness, fall risk
Call-Exner bodies, Inhibin+
MC benign growth in breast
Renal CA assoc w/ Von Hippel-Lindau
MCC testis CA >50yo
low value w/ anovulation: failure to centrally stimulate follicular growth
Ovarian tumor w/ KRAS and BRAF mutations
Appendix epididymis remnant of ?
Assoc w/ uterine hyperplasia/CA in postmenopausal women
antepartum hemorrhage after 20 wks
C/I for anticholinergic therapy
umbilical cord inserts into the fetal membranes
testicular torsion perinatal only
medical tx: urge incontinence
MC infiltrating breast Ca
Removal of breast, pec minor and axillary lymph node
Lady on tamoxifen w/ post-menopausal bleeding - next step?
e of incontinence: unstable bladder
MC Tx of superficial bladder cancer
screening for nonpalpable breast masses
Tumor marker for choriocarcinoma, embryonal carcinoma
Tumor from dense fibroconnective tissue of the breast
Tx symptomatic bone mets (prostate CA)
oligohydramnios and 'key hole' sign
Adnexal mass in reproductive age female, first r/o?
Tx: tubal factor infertility
Induce fetal lung maturity - give mom ?
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
% of complex hyperplasia that progressed to cancer
'blue dot' sign and pain related to inflammation
bleeding but os is open or closed, but still viable pregnancy
HTN after 20 wk w/o proteinuria
Major SE of contraceptive implants
MC group of aneuploidy in spont ab
Endometrial glands/stroma implanted outside uterine cavity/walls
hormone causing ovulation
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
first line hormonal therapy of metastatic breast Ca in premenopausal
hormonal therapy of metastatic breast Ca causing chemical castration
MC location of transitional cell cancer
Rx: adjuvant therapy for postmenopausal breast Ca
Progestin in BCPs derived from spironolactone
dilatation of ducts, inspissated (thick) secretions
MC site of mets in metastatic breast cancer
presence of endometrial glands in uterine myometrium
HPV: Binds rB allowing for cell immortalization
Lab value inc if patient is not making sperm
Marker WT-1
MC site of involvement in endometriosis
Tx PUV: Incise valve to damage leaflet
division of ovum after 13 days
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
Papillary projections surrounded by Schiller-Duval bodies
If surgery unavailable for testicular torson, reduce by twisting?
Oral contraceptive in breastfeeding woman
hypogonadotropic hypogonadism and anosmia
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
breast path - clown face
Colposcopy: cells w/ inc collagen turn white w/ ?
Worst SE of Magnesium sulfate
Perimenopausal uterine bleeding, first step?
intraurethral Rx for ED
best imaging modality for tubal infertility
Hallmark pathological finding of granulosa cell tumots
Grading scheme for prostatic adenocarcinoma
Endometrium that has been hormonally influenced by pregnancy
intraabdominal pregnancy, later found in a 60yo woman
Infection causing bladder CA
ovarian neoplasm w/ 3 germinal layers
L1 proteins from HPV strains self-assemble into non-infectious units called?
Lowest contraceptive failure rates
Other name for ovarian fibroma
Origin of 90% ovarian cancers (aka MC form)
monoclonal ab to HER-2 neu
Prevent sz in preeclampsia

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