8b GUG

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Can you name the 8b GUG?

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MC cystic mass in reproductive-age women
most prostate CA develops in which zone?
Chemo combo for advanced bladder CA
Cells that convert adrenal steroids to estrone
MC group of aneuploidy in spont ab
MC site of ectopic pregnant
2nd most common primary site of mets to ovary
postmenopausal, complex hyperplasia w/ atypia - tx?
Long acting Rx for ED
HRT: w/ uterus, need estrogen and ?
#1 killer of neonates
dilatation of ducts, inspissated (thick) secretions
Most important prognostic factor in breast Ca
Flow of urine in retrograde fashion (to kidney) w/ voiding
MC ovarian germ cell tumor
% of complex hyperplasia that progressed to cancer
low value w/ anovulation: failure to centrally stimulate follicular growth
Removal of breast, pec minor and axillary lymph node
Composition of staghorn stone
BPH Rx SE: orthostasis, dizziness, fall risk
MC Tx of superficial bladder cancer
MC site of involvement in endometriosis
Lowest contraceptive failure rates
Abnormally deep implantation onto the myometrium
MC ovarian tumor (and cancer)
implantation into cornu of uterus or lower uterine segment
Tx of choice for vaginal atrophy
Most important reason fertility dec w/ female age is increasing ?
MC type of endometrial carcinoma
oligohydramnios and 'key hole' sign
MC tumor of myometrium
Rx: adjuvant therapy for ER+ premenopausal breast Ca
Classic path change - failure of conversion of maternal vessels from low volume-high resistance to a high volume-low resistance system
hypogonadotropic hypogonadism and anosmia
amenorrhea w/ high serum androgens, nl estrogen, low progesterone
intraurethral Rx for ED
HTN dx in first 20 weeks of pregnancy
first line hormonal therapy of metastatic breast Ca in postmeno
mech of finasteride, dutasteride
Mutation assoc w/ high grade endometrioid tumors
Name: loss of cell polarity, inc N:C, irreg shape, prominent nucleoli
Type of incontinence: neurogenic dysfunction
Endometrial glands/stroma implanted outside uterine cavity/walls
Chromosome of BRCA-2
Still a cause of maternal and fetal death
Grading scheme for prostatic adenocarcinoma
MCC Epididymal Orchitis in young men
tx: stress urinary incontinence that inc sphincter tone
Varicocele finding on U/S
MC histology of cervival CA
malignant germ cell tumor: AFP
Tumor marker for endodermal sinus tumor, embryonal carcinoma
Type of cancer after tx for mediastinal mass in college age woman
Tx symptomatic bone mets (prostate CA)
% of complex atypical hyperplasia that progressed to cancer
'blue dot' sign and pain related to inflammation
presence of endometrial glands in uterine myometrium
Special type breast CA, high grade but good prognosis
male contraceptive = exogenous hormone?
Uterine size discrepant from dates
Dz: epidermis of nipple contains tumor cells
Perimenopausal uterine bleeding, first step?
Hemangioblastoma of cerebellum and retina, renal cysts and RCC
MC site of mets in metastatic breast cancer
MCC abnml uterine bleeding in postmenopausal
Malignant tumor of admixed proliferating trophoblasts, no villi
hormonal therapy of metastatic breast Ca causing chemical castration
pain with sex
normal strict morphology required to bind to?
Induce fetal lung maturity - give mom ?
Rx: adjuvant therapy for postmenopausal breast Ca
MC neoplasm in young men
MC location of transitional cell cancer
MCC male infertility in the world
breast path - clown face
Tumor marker for dysgerminoma
Targeted therapy for HER2+ breast CA
MC testicular tumor
Prevent sz in preeclampsia
Most common estrogenic ovarian tumor
Kidney CA stage T4, invades
'powder burn' lesions
Major SE of contraceptive implants
Type of incontinence: outlet obstruction
Lab value inc if patient is not making sperm
MC method of contraception
exogenous testosterone leads to ? type of kidney stones
Deletion or unbalanced translocation of chromosome 3 (VKL gene)
screening for nonpalpable breast masses
Antigen that lyses seminal coagulum
medical tx: urge incontinence
Thin, long unilocular mass, associated with period
Hallmark pathological finding of granulosa cell tumots
L1 proteins from HPV strains self-assemble into non-infectious units called?
MC benign growth in breast
Chromosome 17, 85% lifetime breast Ca risk
MC breast carcinoma in situ
sudden huge increase in PSA likely due to?
Tumor marker for choriocarcinoma, embryonal carcinoma
trophoblastic proliferation, fetus or fetal tissue present
Stage: detected from elevated PSA alone, normal DRE & TRUS
% of simple hyperplasia that progressed to cancer
Sperm with DNA damage is assoc w/ ?
Lady on tamoxifen w/ post-menopausal bleeding - next step?
malignant germ cell tumor: beta HCG
reflex test to triage ASCUS pap smear in women > 21
Origin of 90% ovarian cancers (aka MC form)
MC histiological subtype of endometrial CA
Contraception w/ dec efficacy at higher BMI i.e. >198 lbs
MCC UTO in male children
testicular torsion perinatal only
IUD c/i in Wilson's disease
Bladder cancer sx in 85% of cases
Amniotic Fluid Index >90th %ile
Oral contraceptive in breastfeeding woman
Inc prolif of glands rel to stroma 2/2 inactivation of ? gene
MC trisomy in spontaneous abortion
beta 2 receptors cause uterine ?
first line hormonal therapy of metastatic breast Ca in premenopausal
HTN after 20 wk gestation assoc w/ proteinuria
How to stage endometrial CA
MCC abnml uterine bleeding in adolescence
Proper name for 'chocolate cyst'
6 months w/o period
measure seminal vesciles - dilated due to?
Class of Rx for urge incontinence to dec contractility
pau d' orange, cancer cells in dermal lymphatics
Other name for ovarian fibroma
Penile CA 0% in men who are ?
twins share chorion but one gets more blood flow
Main mode of spread of ovarian cancer
MC renal tumor
ovarian neoplasm w/ 3 germinal layers
Worst SE of Magnesium sulfate
Endometrium that has been hormonally influenced by pregnancy
Higher percent of free PSA (25%+)
Condition during lactation, mimics inflammatory breast cancer
Converts androgens to estrogen
CA w/ high rate of extra-uterine dz, NO myometrial invasion of tumor
Bilateral ovarian mets w/ signet ring
monoclonal ab to HER-2 neu
Syndrome: AD w/ 85% penetrance, BRCA
Syndrome w/ inc risk of colon, ovarian, endometrial, breast and uroepithelial CA
bleeding but os is open or closed, but still viable pregnancy
Tx: antagonist in breast; agonist in endometrium
MC infiltrating breast Ca
Rx SE: PSA drops in half, ED, loss of libido
Sv consequence of anovulatory cycle
MC aneuploidy in abortuses
Tx: tubal factor infertility
class of Rx for urge incontinence to tighten outlet
Call-Exner bodies, Inhibin+
CA most strongly associated w/ obesity
Zone sampled in pap smear and biopsy
Tumor from dense fibroconnective tissue of the breast
20-25% of adnexal masses, dx b/t age 10-30yo
Adnexal mass in reproductive age female, first r/o?
Marker WT-1
intraabdominal pregnancy, later found in a 60yo woman
trophoblastic proliferation, cystic villi, no fetal tissue
malignant germ cell tumor: PLAP, Oct 3/4, cKIT
MC gynecological CA worldwide
acute infection w/ obstruction -1st step?
Tumor marker of stromal cell tumors
highest risk of prostate CA starting at what age?
elevated seminal leukocyte count aka?
If surgery unavailable for testicular torson, reduce by twisting?
Type II endometrial carcinoma assoc w/ ?
Molecular? Type I, proliferative - simple hyperplasia
% of simple atypical hyperplasia that progressed to cancer
Renal CA assoc w/ Von Hippel-Lindau
Any condition irritating the periotoneal lining inc which marker?
umbilical cord inserts into the fetal membranes
Why is stage I breast Ca 10-year survival only 75%?
Colposcopy: cells w/ inc collagen turn white w/ ?
HPV: Degrades p53 in the host cell
antepartum hemorrhage after 20 wks
Infection causing bladder CA
Most important RF for uterine CA
Rx w/ SE: endometrial polyps
Mech: Change in transport speed of the ovum
HTN after 20 wk w/o proteinuria
Tx PUV: Incise valve to damage leaflet
Tumor, sx: precocious puberty, hyperandrogenism, pelvic mass/pain
hormone causing ovulation
C/I for anticholinergic therapy
e of incontinence: unstable bladder
best imaging modality for tubal infertility
MC composition of kidney stones
Papillary projections surrounded by Schiller-Duval bodies
Ovarian tumor w/ KRAS and BRAF mutations
proliferation marker in endometrial cycle
Best available protection against STIs
Permanent cessation of menses x1yr w/ high FSH, low E2
lobular (breast) carcinoma in situ is assoc w/ invasive cancer where ?
Signet ring cells in ovary = ?
Molecular? Type I, simple - complex hyperplasia
abnormal dev of chorionic villi in pregnancy can become?
Tumor marker of seminoma
MCC testis CA >50yo
Progestin in BCPs derived from spironolactone
Given to prevent CW recurrence at mastectomy site
division of ovum after 13 days
Appendix testes remnant of ?
Targeted therapy for ER+ breast CA
Contraceptive w/ SE: irregular bleeding, weight gain, bone loss
Assoc w/ uterine hyperplasia/CA in postmenopausal women
MC gynecologic CA
Mutation in mucinous ovarian tumors
Breast duct/lobule cells that produce milk
MC site to endometriosis
MCC of amenorrhea (after pregnancy)
Tx: stimulate ovary - induce endogenous FSH release
HPV: Binds rB allowing for cell immortalization
Appendix epididymis remnant of ?

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