Immunology Vaccines, Microbes, Immunosuppressants

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Can you name the vaccine, virus, bacteria, or immunosuppressant??

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Human antibody
Microbe that inhibits phagolysosome fusion
When producing monoclonal antibodies, the fusion partner is a tumor B cell lacking what enzyme?
Anti-TNF with chimeric receptor
Expresses sialic acid which inhibits C3 and C5 convertases
Virus that blocks effector cell activation and produces soluble IL-1 or IFN-y receptors
Fusion protein on macrophages upregulated in mycobacterial infection that cuases formation of giant cells
Anti-CD20 chimeric monoclonal antibody
Virus that inhibits proteasomal activity and removes class I MHC molecules from the ER
Lose depot and stranger signals/adjuvant effect in this type of vaccine
Inhibits purine synthesis
Chimeric mAb
Inhibits IMP dehydrogenase, lowers dGTP levels
Inhibits calcineurin and prevents NFAT migration to the nucleus by binding cyclophilin
Monoclonal antibody indicated for B lymphomas
Lowers pyrimidine nucleotide levels
Immunosuppressant that inhibits T-independent B cell activation
Recombinant fully human TNF-a receptor mAb that has ligand-binding portion fused to IgG
SAP protein in XLP cannot bind this molecule
Humanized mAb
X-linked proliferative syndrome results in EBV and lymphomas due to lack of this signaling protein
Virus that inhibits antigen presentation by interfering with TAP transporter
HintAnswerExtra
Capsular polysaccharide inhibits phagocytosis
Tx of methotrexate toxicity
Synthesizes modified LPS that resists peptide antibiotics
Virus that inhibits proteasomal activity, produces IL-10, inhibits macrophage and DC activation
Alkylating agent that crosslinks DNA-DNA and DNA-protein, blocking DNA replication and inducing cell death
Fungus that escapes phagolysosomes and resides in the cytoplasm of a macrophage
Chimeric anti-TNF monoclonal antibody
Inhibits mTOR and prevents T cells from making proteins for proliferation
Mouse mAb
Inhibits DHFR, lowers purine levels
Metabolite of cyclophosphamide that has a toxicity damaging bladder mucosa
Fully human monoclonal antibody against TNF
Inhibits IL-10 synthesis, good for tx EBV
Tx of acrolein toxicity
Inhibits cyclosporine by binding FKBP
Produces catalase, resisting ROS in phagocytes
Microbe that moves from cell to cell without going extracellular
Flu vaccine that should not be given to children under the age of 8 except in certain circumstances
Expresses NK inhibitor factor and blocks killing by NK cells
M protein blocks C3 binding to organism and C3b binding to complement receptors
Microbe that crosses the placenta and can cause meningitis in newborns

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Created Feb 12, 2013ReportNominate
Tags:Nintendo, extra, immunology, microbe, virus