Immunology Vaccines, Microbes, Immunosuppressants

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Can you name the vaccine, virus, bacteria, or immunosuppressant??

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Alkylating agent that crosslinks DNA-DNA and DNA-protein, blocking DNA replication and inducing cell death
Inhibits calcineurin and prevents NFAT migration to the nucleus by binding cyclophilin
Tx of methotrexate toxicity
Microbe that crosses the placenta and can cause meningitis in newborns
Inhibits mTOR and prevents T cells from making proteins for proliferation
Inhibits IMP dehydrogenase, lowers dGTP levels
Synthesizes modified LPS that resists peptide antibiotics
Mouse mAb
Monoclonal antibody indicated for B lymphomas
Capsular polysaccharide inhibits phagocytosis
Fusion protein on macrophages upregulated in mycobacterial infection that cuases formation of giant cells
Virus that inhibits proteasomal activity, produces IL-10, inhibits macrophage and DC activation
Produces catalase, resisting ROS in phagocytes
Tx of acrolein toxicity
Inhibits purine synthesis
Inhibits cyclosporine by binding FKBP
Lose depot and stranger signals/adjuvant effect in this type of vaccine
Virus that inhibits proteasomal activity and removes class I MHC molecules from the ER
Chimeric mAb
Immunosuppressant that inhibits T-independent B cell activation
Fungus that escapes phagolysosomes and resides in the cytoplasm of a macrophage
Fully human monoclonal antibody against TNF
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Expresses NK inhibitor factor and blocks killing by NK cells
Human antibody
Anti-CD20 chimeric monoclonal antibody
Chimeric anti-TNF monoclonal antibody
Lowers pyrimidine nucleotide levels
Microbe that moves from cell to cell without going extracellular
X-linked proliferative syndrome results in EBV and lymphomas due to lack of this signaling protein
Virus that blocks effector cell activation and produces soluble IL-1 or IFN-y receptors
Flu vaccine that should not be given to children under the age of 8 except in certain circumstances
Metabolite of cyclophosphamide that has a toxicity damaging bladder mucosa
SAP protein in XLP cannot bind this molecule
Virus that inhibits antigen presentation by interfering with TAP transporter
Expresses sialic acid which inhibits C3 and C5 convertases
Inhibits DHFR, lowers purine levels
Recombinant fully human TNF-a receptor mAb that has ligand-binding portion fused to IgG
Inhibits IL-10 synthesis, good for tx EBV
Humanized mAb
Anti-TNF with chimeric receptor
Microbe that inhibits phagolysosome fusion
M protein blocks C3 binding to organism and C3b binding to complement receptors
When producing monoclonal antibodies, the fusion partner is a tumor B cell lacking what enzyme?

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Created Feb 12, 2013ReportNominate
Tags:Nintendo, extra, immunology, microbe, virus