Immunology Vaccines, Microbes, Immunosuppressants

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Can you name the vaccine, virus, bacteria, or immunosuppressant??

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Fusion protein on macrophages upregulated in mycobacterial infection that cuases formation of giant cells
Virus that inhibits proteasomal activity, produces IL-10, inhibits macrophage and DC activation
Inhibits mTOR and prevents T cells from making proteins for proliferation
Flu vaccine that should not be given to children under the age of 8 except in certain circumstances
SAP protein in XLP cannot bind this molecule
Inhibits cyclosporine by binding FKBP
Microbe that crosses the placenta and can cause meningitis in newborns
Produces catalase, resisting ROS in phagocytes
Microbe that inhibits phagolysosome fusion
Inhibits purine synthesis
Lose depot and stranger signals/adjuvant effect in this type of vaccine
Anti-TNF with chimeric receptor
Immunosuppressant that inhibits T-independent B cell activation
Inhibits IMP dehydrogenase, lowers dGTP levels
Inhibits IL-10 synthesis, good for tx EBV
Virus that inhibits antigen presentation by interfering with TAP transporter
Tx of methotrexate toxicity
Human antibody
X-linked proliferative syndrome results in EBV and lymphomas due to lack of this signaling protein
Expresses NK inhibitor factor and blocks killing by NK cells
Mouse mAb
Alkylating agent that crosslinks DNA-DNA and DNA-protein, blocking DNA replication and inducing cell death
Metabolite of cyclophosphamide that has a toxicity damaging bladder mucosa
Anti-CD20 chimeric monoclonal antibody
Tx of acrolein toxicity
Inhibits calcineurin and prevents NFAT migration to the nucleus by binding cyclophilin
Fungus that escapes phagolysosomes and resides in the cytoplasm of a macrophage
Capsular polysaccharide inhibits phagocytosis
Expresses sialic acid which inhibits C3 and C5 convertases
Monoclonal antibody indicated for B lymphomas
Microbe that moves from cell to cell without going extracellular
Inhibits DHFR, lowers purine levels
Lowers pyrimidine nucleotide levels
M protein blocks C3 binding to organism and C3b binding to complement receptors
Fully human monoclonal antibody against TNF
Virus that blocks effector cell activation and produces soluble IL-1 or IFN-y receptors
Chimeric mAb
When producing monoclonal antibodies, the fusion partner is a tumor B cell lacking what enzyme?
Virus that inhibits proteasomal activity and removes class I MHC molecules from the ER
Humanized mAb
Synthesizes modified LPS that resists peptide antibiotics
Chimeric anti-TNF monoclonal antibody
Recombinant fully human TNF-a receptor mAb that has ligand-binding portion fused to IgG

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Created Feb 12, 2013ReportNominate
Tags:Nintendo, extra, immunology, microbe, virus