Immunology Vaccines, Microbes, Immunosuppressants

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Can you name the vaccine, virus, bacteria, or immunosuppressant??

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Fungus that escapes phagolysosomes and resides in the cytoplasm of a macrophage
Microbe that crosses the placenta and can cause meningitis in newborns
X-linked proliferative syndrome results in EBV and lymphomas due to lack of this signaling protein
Microbe that moves from cell to cell without going extracellular
Flu vaccine that should not be given to children under the age of 8 except in certain circumstances
Inhibits cyclosporine by binding FKBP
Expresses NK inhibitor factor and blocks killing by NK cells
Anti-CD20 chimeric monoclonal antibody
Chimeric mAb
SAP protein in XLP cannot bind this molecule
Immunosuppressant that inhibits T-independent B cell activation
Fully human monoclonal antibody against TNF
Human antibody
Inhibits purine synthesis
Inhibits calcineurin and prevents NFAT migration to the nucleus by binding cyclophilin
Lowers pyrimidine nucleotide levels
Virus that blocks effector cell activation and produces soluble IL-1 or IFN-y receptors
Anti-TNF with chimeric receptor
Fusion protein on macrophages upregulated in mycobacterial infection that cuases formation of giant cells
Recombinant fully human TNF-a receptor mAb that has ligand-binding portion fused to IgG
Inhibits mTOR and prevents T cells from making proteins for proliferation
Inhibits IL-10 synthesis, good for tx EBV
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Alkylating agent that crosslinks DNA-DNA and DNA-protein, blocking DNA replication and inducing cell death
Virus that inhibits proteasomal activity and removes class I MHC molecules from the ER
Inhibits DHFR, lowers purine levels
Humanized mAb
Chimeric anti-TNF monoclonal antibody
Synthesizes modified LPS that resists peptide antibiotics
Tx of methotrexate toxicity
Virus that inhibits proteasomal activity, produces IL-10, inhibits macrophage and DC activation
Virus that inhibits antigen presentation by interfering with TAP transporter
Produces catalase, resisting ROS in phagocytes
Tx of acrolein toxicity
Expresses sialic acid which inhibits C3 and C5 convertases
Metabolite of cyclophosphamide that has a toxicity damaging bladder mucosa
Monoclonal antibody indicated for B lymphomas
When producing monoclonal antibodies, the fusion partner is a tumor B cell lacking what enzyme?
Lose depot and stranger signals/adjuvant effect in this type of vaccine
Mouse mAb
Inhibits IMP dehydrogenase, lowers dGTP levels
M protein blocks C3 binding to organism and C3b binding to complement receptors
Capsular polysaccharide inhibits phagocytosis
Microbe that inhibits phagolysosome fusion

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