Immunology Vaccines, Microbes, Immunosuppressants

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Can you name the vaccine, virus, bacteria, or immunosuppressant??

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Virus that inhibits proteasomal activity, produces IL-10, inhibits macrophage and DC activation
Alkylating agent that crosslinks DNA-DNA and DNA-protein, blocking DNA replication and inducing cell death
X-linked proliferative syndrome results in EBV and lymphomas due to lack of this signaling protein
Immunosuppressant that inhibits T-independent B cell activation
Fusion protein on macrophages upregulated in mycobacterial infection that cuases formation of giant cells
Inhibits calcineurin and prevents NFAT migration to the nucleus by binding cyclophilin
Expresses sialic acid which inhibits C3 and C5 convertases
Chimeric anti-TNF monoclonal antibody
Anti-TNF with chimeric receptor
Human antibody
Flu vaccine that should not be given to children under the age of 8 except in certain circumstances
Tx of methotrexate toxicity
Capsular polysaccharide inhibits phagocytosis
Microbe that crosses the placenta and can cause meningitis in newborns
Microbe that inhibits phagolysosome fusion
Recombinant fully human TNF-a receptor mAb that has ligand-binding portion fused to IgG
M protein blocks C3 binding to organism and C3b binding to complement receptors
Inhibits DHFR, lowers purine levels
Synthesizes modified LPS that resists peptide antibiotics
Expresses NK inhibitor factor and blocks killing by NK cells
Virus that inhibits proteasomal activity and removes class I MHC molecules from the ER
Virus that inhibits antigen presentation by interfering with TAP transporter
Inhibits mTOR and prevents T cells from making proteins for proliferation
Lose depot and stranger signals/adjuvant effect in this type of vaccine
Fully human monoclonal antibody against TNF
Metabolite of cyclophosphamide that has a toxicity damaging bladder mucosa
Humanized mAb
Inhibits purine synthesis
SAP protein in XLP cannot bind this molecule
Fungus that escapes phagolysosomes and resides in the cytoplasm of a macrophage
When producing monoclonal antibodies, the fusion partner is a tumor B cell lacking what enzyme?
Lowers pyrimidine nucleotide levels
Inhibits cyclosporine by binding FKBP
Monoclonal antibody indicated for B lymphomas
Produces catalase, resisting ROS in phagocytes
Microbe that moves from cell to cell without going extracellular
Anti-CD20 chimeric monoclonal antibody
Tx of acrolein toxicity
Inhibits IMP dehydrogenase, lowers dGTP levels
Mouse mAb
Chimeric mAb
Inhibits IL-10 synthesis, good for tx EBV
Virus that blocks effector cell activation and produces soluble IL-1 or IFN-y receptors

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