Immunology Vaccines, Microbes, Immunosuppressants

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Can you name the vaccine, virus, bacteria, or immunosuppressant??

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Monoclonal antibody indicated for B lymphomas
SAP protein in XLP cannot bind this molecule
Expresses NK inhibitor factor and blocks killing by NK cells
Lose depot and stranger signals/adjuvant effect in this type of vaccine
Flu vaccine that should not be given to children under the age of 8 except in certain circumstances
Human antibody
Inhibits cyclosporine by binding FKBP
Microbe that inhibits phagolysosome fusion
X-linked proliferative syndrome results in EBV and lymphomas due to lack of this signaling protein
Chimeric mAb
Anti-CD20 chimeric monoclonal antibody
Expresses sialic acid which inhibits C3 and C5 convertases
Tx of methotrexate toxicity
Recombinant fully human TNF-a receptor mAb that has ligand-binding portion fused to IgG
Chimeric anti-TNF monoclonal antibody
Lowers pyrimidine nucleotide levels
Microbe that crosses the placenta and can cause meningitis in newborns
Mouse mAb
Microbe that moves from cell to cell without going extracellular
Humanized mAb
Inhibits IMP dehydrogenase, lowers dGTP levels
Virus that blocks effector cell activation and produces soluble IL-1 or IFN-y receptors
HintAnswerExtra
When producing monoclonal antibodies, the fusion partner is a tumor B cell lacking what enzyme?
Inhibits DHFR, lowers purine levels
Produces catalase, resisting ROS in phagocytes
Tx of acrolein toxicity
Inhibits purine synthesis
Inhibits calcineurin and prevents NFAT migration to the nucleus by binding cyclophilin
Virus that inhibits proteasomal activity and removes class I MHC molecules from the ER
Alkylating agent that crosslinks DNA-DNA and DNA-protein, blocking DNA replication and inducing cell death
Virus that inhibits proteasomal activity, produces IL-10, inhibits macrophage and DC activation
Anti-TNF with chimeric receptor
Synthesizes modified LPS that resists peptide antibiotics
Inhibits IL-10 synthesis, good for tx EBV
Metabolite of cyclophosphamide that has a toxicity damaging bladder mucosa
Inhibits mTOR and prevents T cells from making proteins for proliferation
Fully human monoclonal antibody against TNF
Capsular polysaccharide inhibits phagocytosis
M protein blocks C3 binding to organism and C3b binding to complement receptors
Fungus that escapes phagolysosomes and resides in the cytoplasm of a macrophage
Fusion protein on macrophages upregulated in mycobacterial infection that cuases formation of giant cells
Virus that inhibits antigen presentation by interfering with TAP transporter
Immunosuppressant that inhibits T-independent B cell activation

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Created Feb 12, 2013ReportNominate
Tags:Nintendo, extra, immunology, microbe, virus