Immunology Vaccines, Microbes, Immunosuppressants

Random Science or Nintendo Quiz

Can you name the vaccine, virus, bacteria, or immunosuppressant??

Quiz not verified by Sporcle

How to Play
Fully human monoclonal antibody against TNF
Microbe that crosses the placenta and can cause meningitis in newborns
Tx of acrolein toxicity
Inhibits purine synthesis
Expresses NK inhibitor factor and blocks killing by NK cells
Produces catalase, resisting ROS in phagocytes
Anti-CD20 chimeric monoclonal antibody
Microbe that moves from cell to cell without going extracellular
Immunosuppressant that inhibits T-independent B cell activation
Inhibits cyclosporine by binding FKBP
When producing monoclonal antibodies, the fusion partner is a tumor B cell lacking what enzyme?
Inhibits IMP dehydrogenase, lowers dGTP levels
SAP protein in XLP cannot bind this molecule
X-linked proliferative syndrome results in EBV and lymphomas due to lack of this signaling protein
Mouse mAb
Synthesizes modified LPS that resists peptide antibiotics
Inhibits IL-10 synthesis, good for tx EBV
Virus that inhibits proteasomal activity and removes class I MHC molecules from the ER
Inhibits mTOR and prevents T cells from making proteins for proliferation
Chimeric anti-TNF monoclonal antibody
Capsular polysaccharide inhibits phagocytosis
Alkylating agent that crosslinks DNA-DNA and DNA-protein, blocking DNA replication and inducing cell death
Lose depot and stranger signals/adjuvant effect in this type of vaccine
Virus that blocks effector cell activation and produces soluble IL-1 or IFN-y receptors
Virus that inhibits antigen presentation by interfering with TAP transporter
Inhibits DHFR, lowers purine levels
Human antibody
Microbe that inhibits phagolysosome fusion
Fungus that escapes phagolysosomes and resides in the cytoplasm of a macrophage
Tx of methotrexate toxicity
Expresses sialic acid which inhibits C3 and C5 convertases
Metabolite of cyclophosphamide that has a toxicity damaging bladder mucosa
Chimeric mAb
Virus that inhibits proteasomal activity, produces IL-10, inhibits macrophage and DC activation
Anti-TNF with chimeric receptor
Fusion protein on macrophages upregulated in mycobacterial infection that cuases formation of giant cells
Flu vaccine that should not be given to children under the age of 8 except in certain circumstances
Recombinant fully human TNF-a receptor mAb that has ligand-binding portion fused to IgG
Humanized mAb
Inhibits calcineurin and prevents NFAT migration to the nucleus by binding cyclophilin
Lowers pyrimidine nucleotide levels
Monoclonal antibody indicated for B lymphomas
M protein blocks C3 binding to organism and C3b binding to complement receptors

You're not logged in!

Compare scores with friends on all Sporcle quizzes.
Sign Up with Email
Log In

You Might Also Like...

Show Comments