Immunology Vaccines, Microbes, Immunosuppressants

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Can you name the vaccine, virus, bacteria, or immunosuppressant??

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Inhibits purine synthesis
Anti-TNF with chimeric receptor
Synthesizes modified LPS that resists peptide antibiotics
Alkylating agent that crosslinks DNA-DNA and DNA-protein, blocking DNA replication and inducing cell death
Metabolite of cyclophosphamide that has a toxicity damaging bladder mucosa
Virus that inhibits proteasomal activity, produces IL-10, inhibits macrophage and DC activation
Lowers pyrimidine nucleotide levels
Capsular polysaccharide inhibits phagocytosis
Expresses NK inhibitor factor and blocks killing by NK cells
Fully human monoclonal antibody against TNF
Inhibits mTOR and prevents T cells from making proteins for proliferation
X-linked proliferative syndrome results in EBV and lymphomas due to lack of this signaling protein
Flu vaccine that should not be given to children under the age of 8 except in certain circumstances
Inhibits DHFR, lowers purine levels
Virus that blocks effector cell activation and produces soluble IL-1 or IFN-y receptors
Microbe that moves from cell to cell without going extracellular
Tx of methotrexate toxicity
Fungus that escapes phagolysosomes and resides in the cytoplasm of a macrophage
Microbe that crosses the placenta and can cause meningitis in newborns
Microbe that inhibits phagolysosome fusion
Chimeric anti-TNF monoclonal antibody
Anti-CD20 chimeric monoclonal antibody
Humanized mAb
Produces catalase, resisting ROS in phagocytes
Immunosuppressant that inhibits T-independent B cell activation
Inhibits IL-10 synthesis, good for tx EBV
Human antibody
Virus that inhibits proteasomal activity and removes class I MHC molecules from the ER
Monoclonal antibody indicated for B lymphomas
M protein blocks C3 binding to organism and C3b binding to complement receptors
When producing monoclonal antibodies, the fusion partner is a tumor B cell lacking what enzyme?
Inhibits calcineurin and prevents NFAT migration to the nucleus by binding cyclophilin
Lose depot and stranger signals/adjuvant effect in this type of vaccine
Mouse mAb
Expresses sialic acid which inhibits C3 and C5 convertases
Fusion protein on macrophages upregulated in mycobacterial infection that cuases formation of giant cells
Chimeric mAb
SAP protein in XLP cannot bind this molecule
Inhibits IMP dehydrogenase, lowers dGTP levels
Inhibits cyclosporine by binding FKBP
Virus that inhibits antigen presentation by interfering with TAP transporter
Tx of acrolein toxicity
Recombinant fully human TNF-a receptor mAb that has ligand-binding portion fused to IgG

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