Generations of Cephalosporins

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Can you name the Cephalosporin?

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Third generation cephalosporin for pseudomonas
Intramuscular surgical prophylaxis
Establishes good levels in CSF relative to concentrations need to inhibit or kill
Fourth generation cephalosporin for pseudomonas
Crosses BBB
Second generation for otitis media and bacterial bronchitis
Active against MRSA
Widely used at the Texas Medical Center
Binds PBP 2' (2a)
Can be given in place of nafcillin/semi-synthetic penicillin in those with h/o penicillin rash
Intra-abdominal surgery prophylaxis
First generation oral surgical prophylaxis
Only third generation good for penicillin resistant pneumococci

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