Generations of Cephalosporins

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Can you name the Cephalosporin?

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First generation oral surgical prophylaxis
Intramuscular surgical prophylaxis
Can be given in place of nafcillin/semi-synthetic penicillin in those with h/o penicillin rash
Widely used at the Texas Medical Center
Establishes good levels in CSF relative to concentrations need to inhibit or kill
Third generation cephalosporin for pseudomonas
Intra-abdominal surgery prophylaxis
Fourth generation cephalosporin for pseudomonas
Second generation for otitis media and bacterial bronchitis
Crosses BBB
Active against MRSA
Binds PBP 2' (2a)
Only third generation good for penicillin resistant pneumococci

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