Generations of Cephalosporins

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Can you name the Cephalosporin?

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Intramuscular surgical prophylaxis
Crosses BBB
Fourth generation cephalosporin for pseudomonas
Binds PBP 2' (2a)
First generation oral surgical prophylaxis
Second generation for otitis media and bacterial bronchitis
Intra-abdominal surgery prophylaxis
Only third generation good for penicillin resistant pneumococci
Can be given in place of nafcillin/semi-synthetic penicillin in those with h/o penicillin rash
Third generation cephalosporin for pseudomonas
Widely used at the Texas Medical Center
Active against MRSA
Establishes good levels in CSF relative to concentrations need to inhibit or kill

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