Generations of Cephalosporins

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Can you name the Cephalosporin?

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Binds PBP 2' (2a)
Only third generation good for penicillin resistant pneumococci
First generation oral surgical prophylaxis
Active against MRSA
Crosses BBB
Intramuscular surgical prophylaxis
Widely used at the Texas Medical Center
Establishes good levels in CSF relative to concentrations need to inhibit or kill
Third generation cephalosporin for pseudomonas
Can be given in place of nafcillin/semi-synthetic penicillin in those with h/o penicillin rash
Intra-abdominal surgery prophylaxis
Fourth generation cephalosporin for pseudomonas
Second generation for otitis media and bacterial bronchitis

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