Generations of Cephalosporins

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Can you name the Cephalosporin?

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Binds PBP 2' (2a)
First generation oral surgical prophylaxis
Active against MRSA
Fourth generation cephalosporin for pseudomonas
Crosses BBB
Intramuscular surgical prophylaxis
Second generation for otitis media and bacterial bronchitis
HintType
Widely used at the Texas Medical Center
Can be given in place of nafcillin/semi-synthetic penicillin in those with h/o penicillin rash
Establishes good levels in CSF relative to concentrations need to inhibit or kill
Intra-abdominal surgery prophylaxis
Only third generation good for penicillin resistant pneumococci
Third generation cephalosporin for pseudomonas

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