Generations of Cephalosporins

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Can you name the Cephalosporin?

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Intra-abdominal surgery prophylaxis
Widely used at the Texas Medical Center
Active against MRSA
Second generation for otitis media and bacterial bronchitis
Binds PBP 2' (2a)
Only third generation good for penicillin resistant pneumococci
Can be given in place of nafcillin/semi-synthetic penicillin in those with h/o penicillin rash
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Crosses BBB
Fourth generation cephalosporin for pseudomonas
Third generation cephalosporin for pseudomonas
First generation oral surgical prophylaxis
Intramuscular surgical prophylaxis
Establishes good levels in CSF relative to concentrations need to inhibit or kill

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