Generations of Cephalosporins

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Can you name the Cephalosporin?

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Widely used at the Texas Medical Center
First generation oral surgical prophylaxis
Active against MRSA
Only third generation good for penicillin resistant pneumococci
Crosses BBB
Binds PBP 2' (2a)
Intra-abdominal surgery prophylaxis
Fourth generation cephalosporin for pseudomonas
Can be given in place of nafcillin/semi-synthetic penicillin in those with h/o penicillin rash
Intramuscular surgical prophylaxis
Third generation cephalosporin for pseudomonas
Second generation for otitis media and bacterial bronchitis
Establishes good levels in CSF relative to concentrations need to inhibit or kill

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