MVST1B BOD Pathology Viruses

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Can you name the MVST1B BOD Pathology Viruses?

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Enter best matching virusVirus
Successfully targetted by interferon therapy
Generally infectious as M-tropic, mutating to T-tropic later
a toga/flavi virus zoonotic infection growing in macrophages as well as directly attacking endothelium. Can cause haemorrhagic fever.
Codes soluble interferon receptors
lytic, liberated en mass (thus AB and IgA important), stable in environment and requires quarantine and slaughter. picorna virus.
targetted by a sialic acid analogue
a reo virus - causes infantile diarrhoea, superficial and acute
A corona virus
can cause congenital malformation thus vaccinated against
subtype of herpes causing genital herpes
Can induce cell transformation
persistent infection causing common warts or genital warts or genital warts
codes Fc receptor molecules to evade antibody response
bullet shaped helical capsid
zoonotic systemic and cns infection, high morbidity
faeco-oral transmitted infection targetted by a killed vaccine
Toga/flavi virus, classical version of recent pandemic
A calci virus, responsible for winter vomiting disease
causes cell stimulation via cell-cycle entry factors and codes a protein to retain MHC1 in ER. Respiratory and enteric types
causes contagious neoplastic disease in chickens
associated with cervical cancer
a picorna virus
Infects RBC precursors, bad for anaemic patients. Leads to enteritis. ssDNA non-enveloped.
causes Kaposi's sarcoma
a paramyxo virus
Used to deliver smallpox vaccine
causes burkitt's lymphoma and glandular fever
acute in b cells and latent in memory b cells
subtype of herpes causing cold sores
Enter best matching virusVirus
causes a highly lytic hepatitis, picornavirus
papova virus causing experimental rodent tumors
Codes a viral EGF for cell stimulation
systemic infection spread along blood/lymph/nerve tracts
targetted by tamiflu
wbc infection that can persist in the CNS to cause a chronic demyelinating disease. ssRNA enveloped.
causes cell stimulation and encodes enzymes to increase nucleotide availability. Latent infection
causes common cold and susceptibility to secondary infection
a toga/flavi virus causing acute and chronic hepatitis
has multiple entry/exit routes, infecting monocytes latently and macrophages acutely. bad in the immunocompromised
A hepadna virus
targetted by a virus-like particle vaccine (capsid w/o nucleic acid)
live attenuated vaccine can rid this infection commonly caught in early school years, infecting WBCs.
dsDNA virus replicating cytosolicly as contains transcription materials in virion
Codes ribonucleotide reducing enzymes (produces dNTP)
causes acute enteric infection and myelitis in the CNS
causes bronchitis, recent talk of vaccine
targetted by aciclovir/acyclovir
treated by quarantine, animal slaughter, immune serum and killed vaccine. May in future be targetted by rational attenuation, or a surface Ag in vaccinia (used on foxes)
causes membrane modification
encephalitis causing toga/flavi virus
a rhabdo virus
causes chicken pox (mucosal infection) and shingles (reactivation from latent in sensory neurones)
Retrovirus
example of polyprotein processing by post-transcriptional cleavage (chemo targets)
acquired via respiratory route but a systemic infection. Acute, only in humans, antigenically stable. Infects WBCs.
related to measles and resp syncytial virus, entering via resp tract
Main example of an orthomyxovirus

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