MVST1B BOD Pathology Viruses

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Can you name the MVST1B BOD Pathology Viruses?

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causes chicken pox (mucosal infection) and shingles (reactivation from latent in sensory neurones)
targetted by aciclovir/acyclovir
causes cell stimulation and encodes enzymes to increase nucleotide availability. Latent infection
Used to deliver smallpox vaccine
A calci virus, responsible for winter vomiting disease
causes acute enteric infection and myelitis in the CNS
Successfully targetted by interferon therapy
papova virus causing experimental rodent tumors
Toga/flavi virus, classical version of recent pandemic
bullet shaped helical capsid
Can induce cell transformation
A hepadna virus
Retrovirus
persistent infection causing common warts or genital warts or genital warts
zoonotic systemic and cns infection, high morbidity
wbc infection that can persist in the CNS to cause a chronic demyelinating disease. ssRNA enveloped.
Codes ribonucleotide reducing enzymes (produces dNTP)
a reo virus - causes infantile diarrhoea, superficial and acute
systemic infection spread along blood/lymph/nerve tracts
faeco-oral transmitted infection targetted by a killed vaccine
Generally infectious as M-tropic, mutating to T-tropic later
subtype of herpes causing genital herpes
a picorna virus
a toga/flavi virus zoonotic infection growing in macrophages as well as directly attacking endothelium. Can cause haemorrhagic fever.
targetted by a sialic acid analogue
associated with cervical cancer
Codes a viral EGF for cell stimulation
can cause congenital malformation thus vaccinated against
targetted by a virus-like particle vaccine (capsid w/o nucleic acid)
Enter best matching virusVirus
a rhabdo virus
a paramyxo virus
has multiple entry/exit routes, infecting monocytes latently and macrophages acutely. bad in the immunocompromised
causes Kaposi's sarcoma
dsDNA virus replicating cytosolicly as contains transcription materials in virion
A corona virus
subtype of herpes causing cold sores
causes contagious neoplastic disease in chickens
Codes soluble interferon receptors
a toga/flavi virus causing acute and chronic hepatitis
causes membrane modification
targetted by tamiflu
related to measles and resp syncytial virus, entering via resp tract
acute in b cells and latent in memory b cells
lytic, liberated en mass (thus AB and IgA important), stable in environment and requires quarantine and slaughter. picorna virus.
causes burkitt's lymphoma and glandular fever
example of polyprotein processing by post-transcriptional cleavage (chemo targets)
causes a highly lytic hepatitis, picornavirus
acquired via respiratory route but a systemic infection. Acute, only in humans, antigenically stable. Infects WBCs.
causes cell stimulation via cell-cycle entry factors and codes a protein to retain MHC1 in ER. Respiratory and enteric types
codes Fc receptor molecules to evade antibody response
causes bronchitis, recent talk of vaccine
Main example of an orthomyxovirus
Infects RBC precursors, bad for anaemic patients. Leads to enteritis. ssDNA non-enveloped.
causes common cold and susceptibility to secondary infection
encephalitis causing toga/flavi virus
treated by quarantine, animal slaughter, immune serum and killed vaccine. May in future be targetted by rational attenuation, or a surface Ag in vaccinia (used on foxes)
live attenuated vaccine can rid this infection commonly caught in early school years, infecting WBCs.

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Created May 21, 2010ReportNominate
Tags:pathology, virus