MVST1B BOD Pathology Viruses

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Can you name the MVST1B BOD Pathology Viruses?

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Main example of an orthomyxovirus
Generally infectious as M-tropic, mutating to T-tropic later
dsDNA virus replicating cytosolicly as contains transcription materials in virion
codes Fc receptor molecules to evade antibody response
faeco-oral transmitted infection targetted by a killed vaccine
a toga/flavi virus zoonotic infection growing in macrophages as well as directly attacking endothelium. Can cause haemorrhagic fever.
subtype of herpes causing genital herpes
subtype of herpes causing cold sores
a reo virus - causes infantile diarrhoea, superficial and acute
Toga/flavi virus, classical version of recent pandemic
Codes ribonucleotide reducing enzymes (produces dNTP)
causes burkitt's lymphoma and glandular fever
causes common cold and susceptibility to secondary infection
papova virus causing experimental rodent tumors
bullet shaped helical capsid
live attenuated vaccine can rid this infection commonly caught in early school years, infecting WBCs.
targetted by a virus-like particle vaccine (capsid w/o nucleic acid)
causes a highly lytic hepatitis, picornavirus
causes contagious neoplastic disease in chickens
example of polyprotein processing by post-transcriptional cleavage (chemo targets)
A corona virus
Codes a viral EGF for cell stimulation
wbc infection that can persist in the CNS to cause a chronic demyelinating disease. ssRNA enveloped.
has multiple entry/exit routes, infecting monocytes latently and macrophages acutely. bad in the immunocompromised
causes chicken pox (mucosal infection) and shingles (reactivation from latent in sensory neurones)
a rhabdo virus
causes cell stimulation via cell-cycle entry factors and codes a protein to retain MHC1 in ER. Respiratory and enteric types
a picorna virus
related to measles and resp syncytial virus, entering via resp tract
Enter best matching virusVirus
systemic infection spread along blood/lymph/nerve tracts
A calci virus, responsible for winter vomiting disease
persistent infection causing common warts or genital warts or genital warts
a paramyxo virus
Can induce cell transformation
causes membrane modification
Retrovirus
treated by quarantine, animal slaughter, immune serum and killed vaccine. May in future be targetted by rational attenuation, or a surface Ag in vaccinia (used on foxes)
associated with cervical cancer
acute in b cells and latent in memory b cells
causes Kaposi's sarcoma
acquired via respiratory route but a systemic infection. Acute, only in humans, antigenically stable. Infects WBCs.
encephalitis causing toga/flavi virus
Codes soluble interferon receptors
zoonotic systemic and cns infection, high morbidity
causes bronchitis, recent talk of vaccine
targetted by tamiflu
causes cell stimulation and encodes enzymes to increase nucleotide availability. Latent infection
Successfully targetted by interferon therapy
A hepadna virus
lytic, liberated en mass (thus AB and IgA important), stable in environment and requires quarantine and slaughter. picorna virus.
a toga/flavi virus causing acute and chronic hepatitis
Infects RBC precursors, bad for anaemic patients. Leads to enteritis. ssDNA non-enveloped.
targetted by aciclovir/acyclovir
Used to deliver smallpox vaccine
can cause congenital malformation thus vaccinated against
targetted by a sialic acid analogue
causes acute enteric infection and myelitis in the CNS

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Created May 21, 2010ReportNominate
Tags:pathology, virus