MVST1B BOD Pathology Viruses

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Can you name the MVST1B BOD Pathology Viruses?

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Enter best matching virusVirus
causes acute enteric infection and myelitis in the CNS
example of polyprotein processing by post-transcriptional cleavage (chemo targets)
has multiple entry/exit routes, infecting monocytes latently and macrophages acutely. bad in the immunocompromised
a rhabdo virus
A hepadna virus
systemic infection spread along blood/lymph/nerve tracts
lytic, liberated en mass (thus AB and IgA important), stable in environment and requires quarantine and slaughter. picorna virus.
persistent infection causing common warts or genital warts or genital warts
a picorna virus
subtype of herpes causing cold sores
live attenuated vaccine can rid this infection commonly caught in early school years, infecting WBCs.
a paramyxo virus
causes cell stimulation via cell-cycle entry factors and codes a protein to retain MHC1 in ER. Respiratory and enteric types
Main example of an orthomyxovirus
causes bronchitis, recent talk of vaccine
bullet shaped helical capsid
causes cell stimulation and encodes enzymes to increase nucleotide availability. Latent infection
Used to deliver smallpox vaccine
causes Kaposi's sarcoma
Codes soluble interferon receptors
Can induce cell transformation
Successfully targetted by interferon therapy
treated by quarantine, animal slaughter, immune serum and killed vaccine. May in future be targetted by rational attenuation, or a surface Ag in vaccinia (used on foxes)
associated with cervical cancer
subtype of herpes causing genital herpes
A calci virus, responsible for winter vomiting disease
dsDNA virus replicating cytosolicly as contains transcription materials in virion
Infects RBC precursors, bad for anaemic patients. Leads to enteritis. ssDNA non-enveloped.
causes chicken pox (mucosal infection) and shingles (reactivation from latent in sensory neurones)
Enter best matching virusVirus
causes contagious neoplastic disease in chickens
targetted by tamiflu
A corona virus
faeco-oral transmitted infection targetted by a killed vaccine
acquired via respiratory route but a systemic infection. Acute, only in humans, antigenically stable. Infects WBCs.
targetted by a virus-like particle vaccine (capsid w/o nucleic acid)
Codes a viral EGF for cell stimulation
causes common cold and susceptibility to secondary infection
encephalitis causing toga/flavi virus
a reo virus - causes infantile diarrhoea, superficial and acute
a toga/flavi virus causing acute and chronic hepatitis
Codes ribonucleotide reducing enzymes (produces dNTP)
targetted by aciclovir/acyclovir
targetted by a sialic acid analogue
papova virus causing experimental rodent tumors
acute in b cells and latent in memory b cells
codes Fc receptor molecules to evade antibody response
causes burkitt's lymphoma and glandular fever
Retrovirus
Toga/flavi virus, classical version of recent pandemic
a toga/flavi virus zoonotic infection growing in macrophages as well as directly attacking endothelium. Can cause haemorrhagic fever.
wbc infection that can persist in the CNS to cause a chronic demyelinating disease. ssRNA enveloped.
causes a highly lytic hepatitis, picornavirus
related to measles and resp syncytial virus, entering via resp tract
can cause congenital malformation thus vaccinated against
zoonotic systemic and cns infection, high morbidity
Generally infectious as M-tropic, mutating to T-tropic later
causes membrane modification

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