MVST1B BOD Pathology Viruses

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Can you name the MVST1B BOD Pathology Viruses?

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Enter best matching virusVirus
Generally infectious as M-tropic, mutating to T-tropic later
a toga/flavi virus causing acute and chronic hepatitis
acquired via respiratory route but a systemic infection. Acute, only in humans, antigenically stable. Infects WBCs.
causes a highly lytic hepatitis, picornavirus
codes Fc receptor molecules to evade antibody response
wbc infection that can persist in the CNS to cause a chronic demyelinating disease. ssRNA enveloped.
example of polyprotein processing by post-transcriptional cleavage (chemo targets)
a paramyxo virus
a reo virus - causes infantile diarrhoea, superficial and acute
can cause congenital malformation thus vaccinated against
systemic infection spread along blood/lymph/nerve tracts
targetted by aciclovir/acyclovir
faeco-oral transmitted infection targetted by a killed vaccine
treated by quarantine, animal slaughter, immune serum and killed vaccine. May in future be targetted by rational attenuation, or a surface Ag in vaccinia (used on foxes)
subtype of herpes causing cold sores
acute in b cells and latent in memory b cells
A hepadna virus
causes bronchitis, recent talk of vaccine
targetted by a sialic acid analogue
targetted by tamiflu
related to measles and resp syncytial virus, entering via resp tract
lytic, liberated en mass (thus AB and IgA important), stable in environment and requires quarantine and slaughter. picorna virus.
subtype of herpes causing genital herpes
bullet shaped helical capsid
causes cell stimulation and encodes enzymes to increase nucleotide availability. Latent infection
a picorna virus
has multiple entry/exit routes, infecting monocytes latently and macrophages acutely. bad in the immunocompromised
targetted by a virus-like particle vaccine (capsid w/o nucleic acid)
a toga/flavi virus zoonotic infection growing in macrophages as well as directly attacking endothelium. Can cause haemorrhagic fever.
Enter best matching virusVirus
A calci virus, responsible for winter vomiting disease
encephalitis causing toga/flavi virus
Main example of an orthomyxovirus
causes burkitt's lymphoma and glandular fever
Retrovirus
A corona virus
causes membrane modification
persistent infection causing common warts or genital warts or genital warts
zoonotic systemic and cns infection, high morbidity
Codes a viral EGF for cell stimulation
Successfully targetted by interferon therapy
papova virus causing experimental rodent tumors
Used to deliver smallpox vaccine
causes chicken pox (mucosal infection) and shingles (reactivation from latent in sensory neurones)
dsDNA virus replicating cytosolicly as contains transcription materials in virion
Toga/flavi virus, classical version of recent pandemic
causes contagious neoplastic disease in chickens
Codes ribonucleotide reducing enzymes (produces dNTP)
Codes soluble interferon receptors
Can induce cell transformation
causes common cold and susceptibility to secondary infection
causes acute enteric infection and myelitis in the CNS
causes Kaposi's sarcoma
associated with cervical cancer
causes cell stimulation via cell-cycle entry factors and codes a protein to retain MHC1 in ER. Respiratory and enteric types
a rhabdo virus
live attenuated vaccine can rid this infection commonly caught in early school years, infecting WBCs.
Infects RBC precursors, bad for anaemic patients. Leads to enteritis. ssDNA non-enveloped.

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Created May 21, 2010ReportNominate
Tags:pathology, virus