Science / MVST1B BOD Pathology Viruses

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Can you name the MVST1B BOD Pathology Viruses?

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Enter best matching virusVirus
example of polyprotein processing by post-transcriptional cleavage (chemo targets)
Can induce cell transformation
faeco-oral transmitted infection targetted by a killed vaccine
has multiple entry/exit routes, infecting monocytes latently and macrophages acutely. bad in the immunocompromised
targetted by tamiflu
papova virus causing experimental rodent tumors
can cause congenital malformation thus vaccinated against
acute in b cells and latent in memory b cells
causes bronchitis, recent talk of vaccine
a paramyxo virus
dsDNA virus replicating cytosolicly as contains transcription materials in virion
causes chicken pox (mucosal infection) and shingles (reactivation from latent in sensory neurones)
encephalitis causing toga/flavi virus
causes cell stimulation via cell-cycle entry factors and codes a protein to retain MHC1 in ER. Respiratory and enteric types
causes acute enteric infection and myelitis in the CNS
Retrovirus
A corona virus
Used to deliver smallpox vaccine
causes contagious neoplastic disease in chickens
targetted by aciclovir/acyclovir
causes Kaposi's sarcoma
targetted by a virus-like particle vaccine (capsid w/o nucleic acid)
causes cell stimulation and encodes enzymes to increase nucleotide availability. Latent infection
Codes a viral EGF for cell stimulation
wbc infection that can persist in the CNS to cause a chronic demyelinating disease. ssRNA enveloped.
lytic, liberated en mass (thus AB and IgA important), stable in environment and requires quarantine and slaughter. picorna virus.
a toga/flavi virus zoonotic infection growing in macrophages as well as directly attacking endothelium. Can cause haemorrhagic fever.
associated with cervical cancer
A calci virus, responsible for winter vomiting disease
Enter best matching virusVirus
acquired via respiratory route but a systemic infection. Acute, only in humans, antigenically stable. Infects WBCs.
causes membrane modification
a reo virus - causes infantile diarrhoea, superficial and acute
treated by quarantine, animal slaughter, immune serum and killed vaccine. May in future be targetted by rational attenuation, or a surface Ag in vaccinia (used on foxes)
subtype of herpes causing cold sores
Infects RBC precursors, bad for anaemic patients. Leads to enteritis. ssDNA non-enveloped.
a rhabdo virus
subtype of herpes causing genital herpes
bullet shaped helical capsid
causes common cold and susceptibility to secondary infection
zoonotic systemic and cns infection, high morbidity
Toga/flavi virus, classical version of recent pandemic
Codes ribonucleotide reducing enzymes (produces dNTP)
Generally infectious as M-tropic, mutating to T-tropic later
codes Fc receptor molecules to evade antibody response
causes burkitt's lymphoma and glandular fever
a picorna virus
live attenuated vaccine can rid this infection commonly caught in early school years, infecting WBCs.
Codes soluble interferon receptors
A hepadna virus
Main example of an orthomyxovirus
causes a highly lytic hepatitis, picornavirus
a toga/flavi virus causing acute and chronic hepatitis
Successfully targetted by interferon therapy
systemic infection spread along blood/lymph/nerve tracts
related to measles and resp syncytial virus, entering via resp tract
targetted by a sialic acid analogue
persistent infection causing common warts or genital warts or genital warts

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