MVST1B BOD Pathology Viruses

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Can you name the MVST1B BOD Pathology Viruses?

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Enter best matching virusVirus
has multiple entry/exit routes, infecting monocytes latently and macrophages acutely. bad in the immunocompromised
Toga/flavi virus, classical version of recent pandemic
related to measles and resp syncytial virus, entering via resp tract
systemic infection spread along blood/lymph/nerve tracts
acquired via respiratory route but a systemic infection. Acute, only in humans, antigenically stable. Infects WBCs.
a rhabdo virus
Main example of an orthomyxovirus
Used to deliver smallpox vaccine
Codes ribonucleotide reducing enzymes (produces dNTP)
a toga/flavi virus causing acute and chronic hepatitis
subtype of herpes causing cold sores
Infects RBC precursors, bad for anaemic patients. Leads to enteritis. ssDNA non-enveloped.
zoonotic systemic and cns infection, high morbidity
A calci virus, responsible for winter vomiting disease
dsDNA virus replicating cytosolicly as contains transcription materials in virion
a reo virus - causes infantile diarrhoea, superficial and acute
acute in b cells and latent in memory b cells
targetted by aciclovir/acyclovir
encephalitis causing toga/flavi virus
causes acute enteric infection and myelitis in the CNS
treated by quarantine, animal slaughter, immune serum and killed vaccine. May in future be targetted by rational attenuation, or a surface Ag in vaccinia (used on foxes)
targetted by a virus-like particle vaccine (capsid w/o nucleic acid)
persistent infection causing common warts or genital warts or genital warts
causes contagious neoplastic disease in chickens
wbc infection that can persist in the CNS to cause a chronic demyelinating disease. ssRNA enveloped.
causes a highly lytic hepatitis, picornavirus
causes membrane modification
causes burkitt's lymphoma and glandular fever
codes Fc receptor molecules to evade antibody response
Enter best matching virusVirus
faeco-oral transmitted infection targetted by a killed vaccine
Can induce cell transformation
subtype of herpes causing genital herpes
Generally infectious as M-tropic, mutating to T-tropic later
bullet shaped helical capsid
example of polyprotein processing by post-transcriptional cleavage (chemo targets)
targetted by tamiflu
a picorna virus
a paramyxo virus
causes chicken pox (mucosal infection) and shingles (reactivation from latent in sensory neurones)
live attenuated vaccine can rid this infection commonly caught in early school years, infecting WBCs.
lytic, liberated en mass (thus AB and IgA important), stable in environment and requires quarantine and slaughter. picorna virus.
can cause congenital malformation thus vaccinated against
A hepadna virus
targetted by a sialic acid analogue
associated with cervical cancer
A corona virus
causes Kaposi's sarcoma
papova virus causing experimental rodent tumors
Successfully targetted by interferon therapy
causes bronchitis, recent talk of vaccine
causes cell stimulation and encodes enzymes to increase nucleotide availability. Latent infection
causes cell stimulation via cell-cycle entry factors and codes a protein to retain MHC1 in ER. Respiratory and enteric types
a toga/flavi virus zoonotic infection growing in macrophages as well as directly attacking endothelium. Can cause haemorrhagic fever.
causes common cold and susceptibility to secondary infection
Codes soluble interferon receptors
Codes a viral EGF for cell stimulation

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Created May 21, 2010ReportNominate
Tags:pathology, virus