MVST1B BOD Pathology Viruses

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Can you name the MVST1B BOD Pathology Viruses?

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Enter best matching virusVirus
a rhabdo virus
causes Kaposi's sarcoma
Can induce cell transformation
can cause congenital malformation thus vaccinated against
papova virus causing experimental rodent tumors
targetted by a virus-like particle vaccine (capsid w/o nucleic acid)
Codes ribonucleotide reducing enzymes (produces dNTP)
causes membrane modification
dsDNA virus replicating cytosolicly as contains transcription materials in virion
acquired via respiratory route but a systemic infection. Acute, only in humans, antigenically stable. Infects WBCs.
causes cell stimulation and encodes enzymes to increase nucleotide availability. Latent infection
Infects RBC precursors, bad for anaemic patients. Leads to enteritis. ssDNA non-enveloped.
A hepadna virus
a toga/flavi virus causing acute and chronic hepatitis
targetted by a sialic acid analogue
systemic infection spread along blood/lymph/nerve tracts
a paramyxo virus
Main example of an orthomyxovirus
Codes soluble interferon receptors
codes Fc receptor molecules to evade antibody response
lytic, liberated en mass (thus AB and IgA important), stable in environment and requires quarantine and slaughter. picorna virus.
causes common cold and susceptibility to secondary infection
targetted by tamiflu
persistent infection causing common warts or genital warts or genital warts
zoonotic systemic and cns infection, high morbidity
causes a highly lytic hepatitis, picornavirus
faeco-oral transmitted infection targetted by a killed vaccine
a reo virus - causes infantile diarrhoea, superficial and acute
subtype of herpes causing genital herpes
Enter best matching virusVirus
example of polyprotein processing by post-transcriptional cleavage (chemo targets)
causes chicken pox (mucosal infection) and shingles (reactivation from latent in sensory neurones)
live attenuated vaccine can rid this infection commonly caught in early school years, infecting WBCs.
encephalitis causing toga/flavi virus
Toga/flavi virus, classical version of recent pandemic
related to measles and resp syncytial virus, entering via resp tract
targetted by aciclovir/acyclovir
has multiple entry/exit routes, infecting monocytes latently and macrophages acutely. bad in the immunocompromised
A corona virus
bullet shaped helical capsid
causes bronchitis, recent talk of vaccine
Retrovirus
a toga/flavi virus zoonotic infection growing in macrophages as well as directly attacking endothelium. Can cause haemorrhagic fever.
treated by quarantine, animal slaughter, immune serum and killed vaccine. May in future be targetted by rational attenuation, or a surface Ag in vaccinia (used on foxes)
subtype of herpes causing cold sores
Codes a viral EGF for cell stimulation
Successfully targetted by interferon therapy
a picorna virus
acute in b cells and latent in memory b cells
wbc infection that can persist in the CNS to cause a chronic demyelinating disease. ssRNA enveloped.
associated with cervical cancer
causes acute enteric infection and myelitis in the CNS
Used to deliver smallpox vaccine
Generally infectious as M-tropic, mutating to T-tropic later
causes contagious neoplastic disease in chickens
causes burkitt's lymphoma and glandular fever
causes cell stimulation via cell-cycle entry factors and codes a protein to retain MHC1 in ER. Respiratory and enteric types
A calci virus, responsible for winter vomiting disease

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