| Hint | Doctor |
| 'Rocky Horror' villain | |
| 'Futurama' staff physician | |
| Founder of Muppet Labs | |
| Muppet band leader | |
| Female sex therapist | |
| Male sex therapist | |
| Oprah sponsored psychologist | |
| Austin Powers nemesis/brother | |
| Mega Man's nemesis | |
| Mary Shelley's mad scientist | |
| 1992 black comedy/slasher film | |
| H.P. Lovecraft's 'Re-Animator' | |
| 'Silence of the Lambs' cannibal | |
| Sherlock Holmes companion | |
| 'The Fugitive' protagonist | |
| 'Half-Life' protagonist | |
| 'Cheers' psychologist | |
| Springfield's competent physician | |
| 'Lost in Space' coward/scientist | |
| Classic Nintendo pill puzzler | |
| 'Aqua Teen Hunger Force' mad scientist | |
| 1964 Kubrick black comedy | |
| Inspector Gadget nemesis | |
| Wild west gunfighter/dentist | |
| 1991 Michael J. Fox comedy | |