Anti HIV agents

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Can you name the Anti HIV drugs?

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Descriptionagentclass
Prevents vertical transmission, adverse reactions: myelosuppression, gi intolerance, hematologic toxicity when given with ganciclovir or ribavirinNRTI
Adverse reaction: skin rash; drug interactions: inhibits cyp3A4 and cyp2C9NNRTI
Adverse reaction: nephrolithiasis, patient must be adequately hydratedPI
Given to pregnant womenPI
Most potent cyp3A4 inhibitor of the protease inhibitors. Used to prolong half life of other PIsPI
Adverse reactions: GI discomfort, rhinitis. Given once dailyPI
Adverse reaction: peripheral neuropathyNRTI
Avoid in patients with PKU, adverse reactions: pancreatitis, retinal changesNRTI
Adverse reactions: jaundice, increased QT intervalPI
Contraindicated in children, adverse reactions: hypersensitivity of palmsNRTI
Descriptionagentclass
Inhibits and induces cyp3A4; adverse reactions: CNS toxicity, Gi intolerance, skin rashNNRTI
Adverse reactions: hypersensitivity, increased risk of CVDNRTI
NucleoTIDE analogueNRTI
Co-administration with TMP-SMZ increases bioavailabilityNRTI
Contraindicated in patients with allergies to sulfanomidesPI
Can cause severe, potentially fatal hepatotoxicityNNRTI
Blocks DNA strand transfer from viral to host genomeIntegrase inhibitor
binds to and inhibits gp41 of HIVFusion inhibitor
Blocks CCR5 co-receptorEntry inhibitor

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