| Villains | Game |
| Bobby Barrows | |
| Dan Barrows (Edward) | |
| Lorenzo Belli | |
| Dahlia Gillespie | |
| Red Crayon Aristocrats | |
| Ghosts of Himuro Mansion | |
| Lord Burroughs | |
| Serial Killer X/The Hate | |
| Necromorphs/'The Marker'/Hive Mind | |
| Sae Kurosawa and other Ghosts of 'The Repentance' | |
| | Villains | Game |
| Pyramid Head | |
| Albert Wesker | |
| SKX/The Oro | |
| Reika Kuze | |
| Claudia Wolf | |
| Alma Wade | |
| William Birkin | |
| Ezechiel Pregzt | |
| Walter Sullivan | |
| Nemesis | |
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