Fluid Balance and Endocrine Regulation

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Can you name the HYTQ?

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True or False: The macula densa cells detect a decrease in Na filtration then through a paracrine mechanism renin is released by the JG cells.
What organ is really important for the regulation of Na and Water levels?
caused by inadequate synthesis or release of ADH due to a head injury or brain tumor. It results in large volumes of urine.
angiotensin II acts at the zona glomerulosa of the adrenal cortex to produce what hormone?
Where in the kidney does ADH act to increase water resorption?
When sodium is ingested, what happens to the osmolality of the body's fluids?
Where in the kidney does angiotensin II act to increase water and sodium intake?
Information from the left atria, aortic arch, and carotid sinus is detected baroreceptors and sent to the brainstem via which two nerves?
Swelling of osmoreceptors inactivates neurons in the SO and PVN nuclei decreasing or inhibiting synthesis and release of ADH at the posterior pituitary.
When osmolality ____, cells in the body shrink
enzyme responsible for converting angiotensin I to angiotensin II
True or False: Thirst is activated by shrinkage of osmoreceptors in the brain.
True or False: angiotensin can act at sympathetic nervous system to inhibit the release of norepinephrine.
Where is angiotensin converting enzyme found?
Total volume of Body Water (L)
Receptor for ANP and BNP
True or False: The V2 receptor activates adenylyl cyclase, increasing cAMP levels, activating protein kinase A, which activates aquaporin 2 channels at the collecting duct of the k
Which ADH receptors are found in the arterioles?
The osmoreceptors in the brain project to which 2 nuclei of the hypothalamus?
What is ANP and BNP's affect on blood vessels?
Angiotensin II binds to what receptor on the JG cells to inhibit renin secretion?
with a decrease in osmolalilty, cell in the body shrink or swell?
True or False: angiotensin II is a negative feedback regulator of renin secretion.
What is angiotensin II affect on blood vessels?
shrinkage of osmoreceptors due to a decrease in water intake (hyperosmolar) activates the neurons in the SO and PVN nuclei of the hypothalamus to induce secretion of what hormone?
True or False: The parasymapthetic nervous system is involved in promoting the secretion of renin.
angiotensinogen is made in the _____.
When plasma is hyposmolar, Is urine volume increased or decreased?
The actions of ANP and BNP primarily oppose the affects of what hormone?
a decrease in blood volume as detected by the baroreceptors of the kidney cause the release of what hormone?
major sites of action for aldosterone in the kidney (2 places)
True or False: ADH increases urine volume.
True or False: Aldosterone acts to increase water excretion.
What natriuretic peptide is made by ventricular myocytes?
What are the 2 natriuretic peptides?
True or False: The secretion of ANP is controlled by activation of stretch receptors in the atria of the heart.
pathological problem that occurs when kidney fails to respond to ADH due to defective V2 receptors or aquaporin 2. causes production of large volumes of urine with normal levels of
cells in the brain that detect changes in osmolality of the extracellular fluid
Where is renin made?
primary control point for the production of angiotensin II
Where are the 2 natriuretic peptides made?
with a ____ in water intake, osmolality increases
What type of catecholamine receptors are located on JG cells promoting renin secretion?
True or False: Aldosterone acts at the collecting duct and distal tubule of the kidney to promote reabsorption of Na and Cl.
an increase in water intake causes a _____ in osmolality
Which ADH receptor is responsible for its actions on the kidney?
What hormone is released by the adrenal cortex can act on the liver stimulating angiotensinogen?
known biomarker of heart failure
Where are the brain osmoreceptors located?
true or false: angiotensin II is produced in the blood.
What natriuretic peptide is made by atrial myocytes?
True or False: ANP and BNP promote Na excretion and water excretion.
True or False: Angiotensin II can act in the brain to increase water and sodium intake.
angiotensin II acts in the brain by using the ______ organs to bypass the blood brain barrier.

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