Adrenal Cortex physiology

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Can you name the HYTQ concepts?

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QuestionAnswer
True or False: overstimulation of cortisol can cause diabetes.
conversion of 11-deoxycortisol to cortisol is catalyzed by what enzyme
T/F: Cortisol can only bind the glucocorticoid receptor.
the region of the adrenal cortex that secretes glucocorticoids
steroidogenesis begins with what compound
pregnenolone is converted to progestrone in which organelle of the cell?
conversion of cholesterol to pregenolone takes place in what organelle
the region of the adrenal cortex that secretes androgens
True or False: Cortisol levels generally peak around midnight.
melanocortin receptor involved in pigmentation
inactive form of cortisol
Pro-opiomelanocortin is the precursor for what hormone released from the anterior pituitary?
A baby born with21 hydroxylase deficiency has ___ blood pressure.
Cortisol acts to _____ lipolysis.
gene responsible for encoding 11 B hydroxysteroid dehydrogenase
True or False: 17 a hydroxylase deficiency causes increased androgens in the blood
catalyzes the conversion of cortisol to cortisone so that it can be inactivated
T/F: Adrenal gland size is proportional to the stimulation of the gland.
A baby born with 21 hydroxylase deficiency will have _____ mineralocorticoid and glucocorticoid levels.
Gene responsible for encoding 3B hydroxysteroid dehydrogenase
can cause ambiguous genitalia in males and absent puberty in females because androgens are not able to be made. can occur as a result of defective CYP17
melanocortin receptor that binds ACTH stimulating steroidogenesis
defective gene in lipoid hyperplasia
channel responsible for transporting cholesterol into the mitochondria
CAH characterized by salt wasting, normal glucocorticoids, normal androgens, and low blood pressure
what catalyzes the conversion of cholesterol to pregnenolone?
A baby born with 11B hydroxylase deficiency high or low glucocorticoids.
these 2 enzymes catalze the conversion of pregnenolone to DHEA.
True or False: A baby born with 11B hydroxylase deficiency will have increased androgen production leading to ambiguous genitalia in females
QuestionAnswer
True or False: The melanocortin family of receptors are G protein coupled receptors.
True or False: 17 a hydroxylase deficiency causes increased blood pressure
True or False: 17 a hydroxylase deficiency causes increased mineralocorticoids and glucocorticoids.
A baby born with defective CYP21 will have high or low levels of ACTH?
Gene responsible for encoding 11B hydrolase
True or False: Cortisol decreases red blood cell production.
patients with an adrenal tumor will have high or low levels of ACTH?
hormone disorder chasracterized by high levels of ACTH. Patients generally have a redistribution of fat to the truncal areas of the body, with muscle wasting at the extremties
responsible for the conversion of corticosterone to aldosterone
this congential adrenal hyperplasia occurs as a result of defective CYP11B2
A baby born with 11B hydroxylase deficiency high or low blood pressure
catalyzes the conversion of progesterone to 11-deoxycorticosterone
True or False: aldosterone synthase deficiency presents with ambiguous genitalia
Cortisol acts to coordinate actions in the muscle and liver. It causes the release of Amino acids by the muscle for uptake by the liver for what metabolic process?
Cortisol cause an increase in gluconeogensis and a _____ in glucose uptake.
T/F: Cortisol acts as a negative feedback regulator at the anterior pituitary and hypothalamus
True or False: Patients with Cushing's disease have normal circadian rhythm of ACTH release.
Secondary Addison's disease is caused by a deficiency of ____.
Primary Addison's disease is caused by a deficiency of ____.
Gene responsible for encoding for aldosterone synthase
the region of the adrenal cortex that secretes mineralocorticoids
Gene responsible for encoding 21 hydroxylase
melanocortin receptor involved in anorexia
True or False: Glucocorticoid and Mineralocorticoid receptors are intracellular acting primarily by regulating transcription
Gene responsible for encoding 17 a hydroxylase and 17 20 desmolase
these 2 enzymes catalze the conversion of pregnenolone to progesterone
ADH (vasopressin) and Corticotropin releasing hormone cause the release of what hormone from the anterior pituitary?
no steroids are made in this disorder
True or False: A female baby born with defective CYP21 has increased production of DHEA, causing ambiguous genitalia.

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