Adrenal Cortex physiology

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QuestionAnswer
True or False: 17 a hydroxylase deficiency causes increased blood pressure
gene responsible for encoding 11 B hydroxysteroid dehydrogenase
Secondary Addison's disease is caused by a deficiency of ____.
the region of the adrenal cortex that secretes androgens
T/F: Cortisol can only bind the glucocorticoid receptor.
can cause ambiguous genitalia in males and absent puberty in females because androgens are not able to be made. can occur as a result of defective CYP17
T/F: Cortisol acts as a negative feedback regulator at the anterior pituitary and hypothalamus
A baby born with 11B hydroxylase deficiency high or low blood pressure
conversion of 11-deoxycortisol to cortisol is catalyzed by what enzyme
True or False: aldosterone synthase deficiency presents with ambiguous genitalia
CAH characterized by salt wasting, normal glucocorticoids, normal androgens, and low blood pressure
A baby born with 21 hydroxylase deficiency will have _____ mineralocorticoid and glucocorticoid levels.
True or False: Glucocorticoid and Mineralocorticoid receptors are intracellular acting primarily by regulating transcription
True or False: The melanocortin family of receptors are G protein coupled receptors.
these 2 enzymes catalze the conversion of pregnenolone to DHEA.
Gene responsible for encoding 21 hydroxylase
Gene responsible for encoding 17 a hydroxylase and 17 20 desmolase
inactive form of cortisol
catalyzes the conversion of cortisol to cortisone so that it can be inactivated
True or False: overstimulation of cortisol can cause diabetes.
steroidogenesis begins with what compound
channel responsible for transporting cholesterol into the mitochondria
no steroids are made in this disorder
melanocortin receptor involved in anorexia
A baby born with21 hydroxylase deficiency has ___ blood pressure.
True or False: Cortisol levels generally peak around midnight.
True or False: Patients with Cushing's disease have normal circadian rhythm of ACTH release.
Cortisol acts to coordinate actions in the muscle and liver. It causes the release of Amino acids by the muscle for uptake by the liver for what metabolic process?
melanocortin receptor involved in pigmentation
QuestionAnswer
True or False: A female baby born with defective CYP21 has increased production of DHEA, causing ambiguous genitalia.
Cortisol acts to _____ lipolysis.
patients with an adrenal tumor will have high or low levels of ACTH?
hormone disorder chasracterized by high levels of ACTH. Patients generally have a redistribution of fat to the truncal areas of the body, with muscle wasting at the extremties
Gene responsible for encoding 11B hydrolase
T/F: Adrenal gland size is proportional to the stimulation of the gland.
Cortisol cause an increase in gluconeogensis and a _____ in glucose uptake.
these 2 enzymes catalze the conversion of pregnenolone to progesterone
Gene responsible for encoding 3B hydroxysteroid dehydrogenase
Pro-opiomelanocortin is the precursor for what hormone released from the anterior pituitary?
catalyzes the conversion of progesterone to 11-deoxycorticosterone
this congential adrenal hyperplasia occurs as a result of defective CYP11B2
ADH (vasopressin) and Corticotropin releasing hormone cause the release of what hormone from the anterior pituitary?
True or False: A baby born with 11B hydroxylase deficiency will have increased androgen production leading to ambiguous genitalia in females
True or False: 17 a hydroxylase deficiency causes increased mineralocorticoids and glucocorticoids.
Primary Addison's disease is caused by a deficiency of ____.
the region of the adrenal cortex that secretes mineralocorticoids
the region of the adrenal cortex that secretes glucocorticoids
what catalyzes the conversion of cholesterol to pregnenolone?
True or False: 17 a hydroxylase deficiency causes increased androgens in the blood
A baby born with defective CYP21 will have high or low levels of ACTH?
defective gene in lipoid hyperplasia
responsible for the conversion of corticosterone to aldosterone
melanocortin receptor that binds ACTH stimulating steroidogenesis
True or False: Cortisol decreases red blood cell production.
conversion of cholesterol to pregenolone takes place in what organelle
A baby born with 11B hydroxylase deficiency high or low glucocorticoids.
Gene responsible for encoding for aldosterone synthase
pregnenolone is converted to progestrone in which organelle of the cell?

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Created Feb 27, 2012ReportNominate
Tags:concept, cortex, physiology