Pulmonary Circulation & Gas Transport in the Blood

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Can you name the Pulmonary Circulation?

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In _____, the O2 content is decreased with a decreased amount of O2 binding to hemoglobin.
The resistance in the extra-alveolar vessels increases on _____. (inspiration or expiration)
When oxygen binds hemoglobin to form oxyhemoglobin, is hemoglobin is a relaxed or tense state?
T/F: The concentration of dissolved oxygen in the blood determines the percent saturation of hemoglobin
When capillaries are already open further increases in blood pressure dilate the vessels, which is known as ____.
T/F: There is more blood flow at the apex of the lung versus the base.
defined as the amount of O2 bound to hemoglobin / the carrying capacity of hemoglobin
T/F: Under normal circumstances, there is no Zone 1 in the lungs
T/F: Low oxygen in alveolar air can act on pulmonary vessels to direct blood away from hypoxic regions and increase pulmonary arterial pressure.
True/ False: Vaso active substances such as prostaglandins, leukotrienes, and angiotensin II are metabolized and/ or removed in the lung
Are the extra-alveolar and alveolar vessels in parallel or series?
At larger lung volumes, what happens to the resistance of the alveolar vessels? (increase or decrease)
When pulmonary arterial and/or venous pressure increases, more fluid enters the interstitial space. If the lymphatic system cannot absorb the fluid, the result is _____.
Lowest total resistance occurs at _____.
An increase in 2, 3 DPG production will cause a ____-ward shift in the oxygen binding curve for hemoglobin.
At total lung capacity, the resistance is the least in the extra-alveolar or alveolar vessels?
T/F: The oxygen dissolved in the blood is enough to meet the body's metabolic needs.
mean arterial pressure in the systemic circulation
An increased pCO2 or a decrease in blood pH will cause a rightward shift of the blood oxygen binding curve to hemoglobin. This is known as the ____ effect.
These vessels are affected by alveolar pressure and includes capillaries surrounding alveoli
T/F: AN increase in temperature, increases oxygen delivery to tissues by changing the conformation of hemoglobin.
As pulmonary arterial pressure increases, what happens to the blood flow? (increases or decreases)
molecule made as a result of metabolism of RBC.... its production is increased under hypoxic conditions
Hemoglobin is 75% saturated at ___ mmHg O2.
As pulmonary arterial pressure increases, what happens to the resistance ? (increases or decreases)
calculated by the [(arterial gas content -venous gas content) x blood flow]
The pulmonary circulation is a ___ compliance system.
In this zone the pulmonary arterial and venous pressures are greater than the alveolar pressures
The ____ circulation supplies the conducting airways.
CO2 can be dissolved in the blood, carried in the form of bicarbonate, or carried as _____ compounds.
QuestionAnswer
In _____, the O2 content is decreased but there is no change in the relationship of oxygen binding to hemoglobin.
what is the carrying capacity of hemoglobin in the blood per 100mL (ml O2 per 100mL of blood.)
In this zone the alveolar pressure exceeds the pulmonary arterial pressure
T/F: Total gas content is calculated by adding the amount carried on hemoglobin and the amount of gas dissolved
A ____-ward shift in the oxygen binding curve to hemoglobin denotes an decrease in oxygen delivery to tissues.
_____ partial pressure of CO2 causes vasoconstriction
Where does recruitment usually occur in the lung.
At larger lung volumes, what happens to the resistance of the extra-alveolar vessels? (increase or decrease)
In this zone the alveolar pressure is less than the pulmonary arterial pressure but it exceeds the pulmonary venous pressure
The resistance in the alveolar vessels increases on _____. (inspiration or expiration)
The content carried by hemoglobin can be calculated by multiplying ____ and _____.
According to Henry;s Law, concentration of dissolved gas is dependent on what two variables.
Low partial pressure of O2 in the alveolar air causes _____ in the small pulmonary arteries
mean arterial pressure in the pulmonary circulation
normal amount of hemoglobin in the blood (in grams/100mL)
A ____-ward shift in the oxygen binding curve to hemoglobin denotes an increase in oxygen delivery to tissues.
True/ False: The total content of CO2 is higher in the blood than O2.
When oxygen is released from hemoglobin to form deoxyhemoglobin, is hemoglobin is a relaxed or tense state?
primary form of CO2 in the blood
At residual volume, the resistance is the least in the extra-alveolar or alveolar vessels?
these vessels are affected by the intrapleural pressure.
Venous partial pressure of oxygen (mm Hg)
T:F: There is a left to right shunt in the pulmonary circulation that arises from blood that does not flow through the pulmonary capillaries to pick up oxygen before it enters the
this substance or gas vasodilates the pulmonary vasculature
Hemoglobin is 90% saturated at ___ mmHg O2.
Hemoglobin is 50% saturated at ___ mmHg O2.
Hemoglobin can hold up to _____ mlO2/g Hemoglobin
As pulmonary arterial pressure increases blood flows through capillaries that previously had little or no blood flow. This is known as _____.
Alveolar vessel resistance is the lowest in which zone?
T/F: The binding of oxygen to hemoglobin is linear

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