Pulmonary Circulation & Gas Transport in the Blood

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Can you name the Pulmonary Circulation?

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At residual volume, the resistance is the least in the extra-alveolar or alveolar vessels?
T/F: Total gas content is calculated by adding the amount carried on hemoglobin and the amount of gas dissolved
An increase in 2, 3 DPG production will cause a ____-ward shift in the oxygen binding curve for hemoglobin.
normal amount of hemoglobin in the blood (in grams/100mL)
When pulmonary arterial and/or venous pressure increases, more fluid enters the interstitial space. If the lymphatic system cannot absorb the fluid, the result is _____.
CO2 can be dissolved in the blood, carried in the form of bicarbonate, or carried as _____ compounds.
In this zone the pulmonary arterial and venous pressures are greater than the alveolar pressures
The ____ circulation supplies the conducting airways.
The content carried by hemoglobin can be calculated by multiplying ____ and _____.
T:F: There is a left to right shunt in the pulmonary circulation that arises from blood that does not flow through the pulmonary capillaries to pick up oxygen before it enters the
defined as the amount of O2 bound to hemoglobin / the carrying capacity of hemoglobin
The resistance in the alveolar vessels increases on _____. (inspiration or expiration)
An increased pCO2 or a decrease in blood pH will cause a rightward shift of the blood oxygen binding curve to hemoglobin. This is known as the ____ effect.
True/ False: Vaso active substances such as prostaglandins, leukotrienes, and angiotensin II are metabolized and/ or removed in the lung
A ____-ward shift in the oxygen binding curve to hemoglobin denotes an increase in oxygen delivery to tissues.
In this zone the alveolar pressure is less than the pulmonary arterial pressure but it exceeds the pulmonary venous pressure
primary form of CO2 in the blood
Where does recruitment usually occur in the lung.
These vessels are affected by alveolar pressure and includes capillaries surrounding alveoli
T/F: The concentration of dissolved oxygen in the blood determines the percent saturation of hemoglobin
As pulmonary arterial pressure increases blood flows through capillaries that previously had little or no blood flow. This is known as _____.
Hemoglobin is 90% saturated at ___ mmHg O2.
Hemoglobin can hold up to _____ mlO2/g Hemoglobin
According to Henry;s Law, concentration of dissolved gas is dependent on what two variables.
Venous partial pressure of oxygen (mm Hg)
T/F: Under normal circumstances, there is no Zone 1 in the lungs
As pulmonary arterial pressure increases, what happens to the resistance ? (increases or decreases)
At larger lung volumes, what happens to the resistance of the extra-alveolar vessels? (increase or decrease)
Hemoglobin is 50% saturated at ___ mmHg O2.
True/ False: The total content of CO2 is higher in the blood than O2.
QuestionAnswer
Hemoglobin is 75% saturated at ___ mmHg O2.
what is the carrying capacity of hemoglobin in the blood per 100mL (ml O2 per 100mL of blood.)
In _____, the O2 content is decreased with a decreased amount of O2 binding to hemoglobin.
T/F: The oxygen dissolved in the blood is enough to meet the body's metabolic needs.
In this zone the alveolar pressure exceeds the pulmonary arterial pressure
T/F: The binding of oxygen to hemoglobin is linear
mean arterial pressure in the pulmonary circulation
calculated by the [(arterial gas content -venous gas content) x blood flow]
In _____, the O2 content is decreased but there is no change in the relationship of oxygen binding to hemoglobin.
When oxygen binds hemoglobin to form oxyhemoglobin, is hemoglobin is a relaxed or tense state?
T/F: Low oxygen in alveolar air can act on pulmonary vessels to direct blood away from hypoxic regions and increase pulmonary arterial pressure.
Alveolar vessel resistance is the lowest in which zone?
At total lung capacity, the resistance is the least in the extra-alveolar or alveolar vessels?
T/F: There is more blood flow at the apex of the lung versus the base.
The pulmonary circulation is a ___ compliance system.
Lowest total resistance occurs at _____.
this substance or gas vasodilates the pulmonary vasculature
molecule made as a result of metabolism of RBC.... its production is increased under hypoxic conditions
Low partial pressure of O2 in the alveolar air causes _____ in the small pulmonary arteries
When oxygen is released from hemoglobin to form deoxyhemoglobin, is hemoglobin is a relaxed or tense state?
T/F: AN increase in temperature, increases oxygen delivery to tissues by changing the conformation of hemoglobin.
At larger lung volumes, what happens to the resistance of the alveolar vessels? (increase or decrease)
Are the extra-alveolar and alveolar vessels in parallel or series?
As pulmonary arterial pressure increases, what happens to the blood flow? (increases or decreases)
mean arterial pressure in the systemic circulation
The resistance in the extra-alveolar vessels increases on _____. (inspiration or expiration)
these vessels are affected by the intrapleural pressure.
When capillaries are already open further increases in blood pressure dilate the vessels, which is known as ____.
_____ partial pressure of CO2 causes vasoconstriction
A ____-ward shift in the oxygen binding curve to hemoglobin denotes an decrease in oxygen delivery to tissues.

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