voltage sensitive receptor in T tubule

L type Ca channel in Sarcoplasmic Reticulum

DHPR and Ryanodine Receptors are mechanically coupled in what type of muscle?

Ca induced Ca Release

Ca induced Ca Release

Responsible for Sequestering Ca via ATP hydrolysis

Arrangement of Muscle Fibers

Muscle shortening against a Fixed Load

Contraction of a sarcomere at a fixed length

Muscle contraction characterized by a Ca release and complete Ca Sequestering

Contraction characterized by Ca release with sustained concentration of Ca in the Myofiber

Slow Twitch or Type I fibers generally use what type of metabolism (aerobic or anaerobic)?

Fast Twitch or Type IIb fibers generally use what type of metabolism (aerobic or anaerobic)?

mechanical strength of intercalated discs

component of the intercalated disc that contributes to fast electrical conduction in cardiac myocytes

Measure of Active Tension in Cardiomyocytes

Measure of Passive Tension in Cardiomyocytes

inhibits SERCA

binds Ca in the SR

The phosphorylation of ______ can decrease binding time of Troponin C to Ca

B adrenergic stimulation leads to phosphorylation of :

B adrenergic stimulation leads to phosphorylation of :

similar to Z disks but are a component of smooth muscle

Invaginations within smooth muscle that contain calcium stores

Phosphorylation of _____ leads to contraction in smooth muscle cells

Ca-calmodulin complex activates this enzyme

T/F: Smooth muscle cells have tropomyosin

T/F: Smooth muscle cells contain B adrenergic receptors that increase IP3 and lead to increased Ca in the cell

Describes an increase in muscle force of contraction at a given sarcomere length

I bands contain filaments of ____

A bands contain ____

H zone contains ____

Marks the end of a sarcomere

X linked recessive disease caused by mutations in Dystrophin

Occurs due to a non functional dystrophin

Occurs due to the presence of a truncated or partial dystrophin

Mutation in a sarcoglycan

This portion of dystrophin binds nNOS

Manifestations of DMD begin to appear at age ___.

inability to get up from floor, often seen in patients with Muscular Dystrophy