Science / Gastric Physiology

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Can you name the Gastric Physiology?

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T/F: Rate of gastric emptying increases with rectal and colonic distention.
T/F: Prilosec or Omeprazole acts at the basolateral membrane of the parietal cell.
This type of drug inhibits prostaglandin related defense mechanisms within the stomach
H2 blockers prevent the binding of ____ to prevent the production of acid.
How does potassium get out of the parietal cell?
this hormone acts on the G cell in the antrum of the stomach to inhibit the release of gastrin
enzyme important for the production of protons and bicarbonate in the parietal cell
T/F: The parietal cell can be activated by Acetylcholine, histamine, or gastrin.
these cells produce gastrin
P/D1 cells release what hormone?
T/F: Ileal fat increase gastric emptying.
failure of the pyloric sphincter to relax for gastric emptying... leads to projectile vomiting
prilosec or omeprazole acts by inhibiting what?
these cells produce histamine
what activates pepsinogen?
leptin is release by which type of tissue?
these cells produce HCl and intrinsic factor
Hypoglycemia ___ (increase or decreases) gastric emptying.
T/F: Large volumes in the stomach increase gastric emptying
T/F: An increase in pH (basicity) slows gastric emptying.
P/D1 cells are located where?
T/F: Proton pump inhibitors bind irreversibly to the H/K proton pump.
pespinogen and HCl are released into the lumen of the stomach... where is histamine released?
T/F: In some cases of peptic ulcer disease, acid from the stomach erodes the D cells of the stomach preventing the brake mechanism for acid production.
T/F: The stomach is the major site for digestion.
Peptide tyrosine-tyrosine (PYY) and glucagon like peptide (GLP1 and GLP2) ____ (stimulates/inhibits) gastric emptying
2nd messenger involved in activation of the parietal cell
responsible for getting H+ ions into the lumen of the stomach
Cl ions are transported into the lumen of the stomach using which type of transport protein?
severely delayed gastric emptying or no emptying
T/F: Tagemet and cimetidine prevent acid production by blocking H1 histamine receptors
These cells in the stomach are activated by the H+ions in the stomach to reduce the release of gastrin
Which histamine receptor is found on the basolateral membrane of the parietal cell?
occurs due to a defiency in vitamin B12, which inhibits the body's ability to go through erythropoesis
this hormone acts at the hypothalamus to suppress appetite
2 causes of peptic ulcers
Secretin ____ (promotes or inhibits) gastric emptying
T/F: Ghelin is released during fasting which stimulates appetite
Cl ions are transported into the parietal cell using which type of transport protein?
The movement of Cl into the parietal cell is coupled to the movement of which ion out of the cell?
The superficial epithelial cells along with which other cell type in the stomach act to lubricate and protect the stomach wall?
CCK ____ (promotes or inhibits) gastric emptying
___ are hormones released by the duodenum and cause feedback on stomach to decrease gastric emptying and secretions
The gland of the stomach is known an ____ gland.
Nutrients in the ileum and the colon influence gastric emptying through the _____ mechanism
made by the I cells of the duodenum
All stomach cell types are activated by the neurotransmitter (from the enteric nervous system) Acetylcholine, except which cell?
occurs due to uncontrolled gastric emptying due to the lack of feedback inhibition by the duodenum and undigested food makes it to the colon
which two products of oxidative phosphorylation are important for the production of stomach acid.
essential for binding and absorption of vitamin B12
these cells produce somatostatin
made by the S cells of the duodenum
T/F: ECL cells can be activated by acetylcholine or gastrin
these cells produce pepsinogen and gastric lipase
T/F: After a large meal, the alkaline tide (removal of bicarbonate from the parietal cell) causes an increase in the pH of the blood.

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