Gastric Physiology

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2 causes of peptic ulcers
Which histamine receptor is found on the basolateral membrane of the parietal cell?
responsible for getting H+ ions into the lumen of the stomach
How does potassium get out of the parietal cell?
Secretin ____ (promotes or inhibits) gastric emptying
T/F: Tagemet and cimetidine prevent acid production by blocking H1 histamine receptors
failure of the pyloric sphincter to relax for gastric emptying... leads to projectile vomiting
2nd messenger involved in activation of the parietal cell
T/F: Ghelin is released during fasting which stimulates appetite
P/D1 cells are located where?
Cl ions are transported into the lumen of the stomach using which type of transport protein?
Nutrients in the ileum and the colon influence gastric emptying through the _____ mechanism
made by the S cells of the duodenum
The movement of Cl into the parietal cell is coupled to the movement of which ion out of the cell?
This type of drug inhibits prostaglandin related defense mechanisms within the stomach
essential for binding and absorption of vitamin B12
T/F: Rate of gastric emptying increases with rectal and colonic distention.
these cells produce gastrin
Hypoglycemia ___ (increase or decreases) gastric emptying.
___ are hormones released by the duodenum and cause feedback on stomach to decrease gastric emptying and secretions
T/F: Proton pump inhibitors bind irreversibly to the H/K proton pump.
these cells produce pepsinogen and gastric lipase
these cells produce somatostatin
these cells produce histamine
The gland of the stomach is known an ____ gland.
All stomach cell types are activated by the neurotransmitter (from the enteric nervous system) Acetylcholine, except which cell?
The superficial epithelial cells along with which other cell type in the stomach act to lubricate and protect the stomach wall?
T/F: ECL cells can be activated by acetylcholine or gastrin
enzyme important for the production of protons and bicarbonate in the parietal cell
T/F: After a large meal, the alkaline tide (removal of bicarbonate from the parietal cell) causes an increase in the pH of the blood.
T/F: Large volumes in the stomach increase gastric emptying
T/F: The stomach is the major site for digestion.
T/F: In some cases of peptic ulcer disease, acid from the stomach erodes the D cells of the stomach preventing the brake mechanism for acid production.
P/D1 cells release what hormone?
H2 blockers prevent the binding of ____ to prevent the production of acid.
T/F: The parietal cell can be activated by Acetylcholine, histamine, or gastrin.
Peptide tyrosine-tyrosine (PYY) and glucagon like peptide (GLP1 and GLP2) ____ (stimulates/inhibits) gastric emptying
pespinogen and HCl are released into the lumen of the stomach... where is histamine released?
leptin is release by which type of tissue?
severely delayed gastric emptying or no emptying
this hormone acts on the G cell in the antrum of the stomach to inhibit the release of gastrin
occurs due to uncontrolled gastric emptying due to the lack of feedback inhibition by the duodenum and undigested food makes it to the colon
T/F: Prilosec or Omeprazole acts at the basolateral membrane of the parietal cell.
occurs due to a defiency in vitamin B12, which inhibits the body's ability to go through erythropoesis
Cl ions are transported into the parietal cell using which type of transport protein?
which two products of oxidative phosphorylation are important for the production of stomach acid.
made by the I cells of the duodenum
T/F: An increase in pH (basicity) slows gastric emptying.
this hormone acts at the hypothalamus to suppress appetite
prilosec or omeprazole acts by inhibiting what?
CCK ____ (promotes or inhibits) gastric emptying
these cells produce HCl and intrinsic factor
These cells in the stomach are activated by the H+ions in the stomach to reduce the release of gastrin
T/F: Ileal fat increase gastric emptying.
what activates pepsinogen?

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