Gastric Physiology

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Cl ions are transported into the parietal cell using which type of transport protein?
How does potassium get out of the parietal cell?
T/F: ECL cells can be activated by acetylcholine or gastrin
This type of drug inhibits prostaglandin related defense mechanisms within the stomach
The superficial epithelial cells along with which other cell type in the stomach act to lubricate and protect the stomach wall?
made by the S cells of the duodenum
T/F: Large volumes in the stomach increase gastric emptying
leptin is release by which type of tissue?
made by the I cells of the duodenum
this hormone acts on the G cell in the antrum of the stomach to inhibit the release of gastrin
essential for binding and absorption of vitamin B12
T/F: Proton pump inhibitors bind irreversibly to the H/K proton pump.
Hypoglycemia ___ (increase or decreases) gastric emptying.
These cells in the stomach are activated by the H+ions in the stomach to reduce the release of gastrin
T/F: Ileal fat increase gastric emptying.
T/F: Tagemet and cimetidine prevent acid production by blocking H1 histamine receptors
The gland of the stomach is known an ____ gland.
T/F: The stomach is the major site for digestion.
these cells produce gastrin
T/F: In some cases of peptic ulcer disease, acid from the stomach erodes the D cells of the stomach preventing the brake mechanism for acid production.
T/F: An increase in pH (basicity) slows gastric emptying.
CCK ____ (promotes or inhibits) gastric emptying
what activates pepsinogen?
prilosec or omeprazole acts by inhibiting what?
Cl ions are transported into the lumen of the stomach using which type of transport protein?
these cells produce somatostatin
pespinogen and HCl are released into the lumen of the stomach... where is histamine released?
All stomach cell types are activated by the neurotransmitter (from the enteric nervous system) Acetylcholine, except which cell?
enzyme important for the production of protons and bicarbonate in the parietal cell
2nd messenger involved in activation of the parietal cell
P/D1 cells release what hormone?
2 causes of peptic ulcers
occurs due to a defiency in vitamin B12, which inhibits the body's ability to go through erythropoesis
P/D1 cells are located where?
T/F: The parietal cell can be activated by Acetylcholine, histamine, or gastrin.
failure of the pyloric sphincter to relax for gastric emptying... leads to projectile vomiting
Nutrients in the ileum and the colon influence gastric emptying through the _____ mechanism
Which histamine receptor is found on the basolateral membrane of the parietal cell?
T/F: Rate of gastric emptying increases with rectal and colonic distention.
Secretin ____ (promotes or inhibits) gastric emptying
___ are hormones released by the duodenum and cause feedback on stomach to decrease gastric emptying and secretions
Peptide tyrosine-tyrosine (PYY) and glucagon like peptide (GLP1 and GLP2) ____ (stimulates/inhibits) gastric emptying
responsible for getting H+ ions into the lumen of the stomach
T/F: Ghelin is released during fasting which stimulates appetite
occurs due to uncontrolled gastric emptying due to the lack of feedback inhibition by the duodenum and undigested food makes it to the colon
severely delayed gastric emptying or no emptying
these cells produce pepsinogen and gastric lipase
this hormone acts at the hypothalamus to suppress appetite
The movement of Cl into the parietal cell is coupled to the movement of which ion out of the cell?
H2 blockers prevent the binding of ____ to prevent the production of acid.
T/F: After a large meal, the alkaline tide (removal of bicarbonate from the parietal cell) causes an increase in the pH of the blood.
which two products of oxidative phosphorylation are important for the production of stomach acid.
T/F: Prilosec or Omeprazole acts at the basolateral membrane of the parietal cell.
these cells produce HCl and intrinsic factor
these cells produce histamine

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Created Mar 25, 2012ReportNominate