Gastric Physiology

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Can you name the Gastric Physiology?

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Secretin ____ (promotes or inhibits) gastric emptying
essential for binding and absorption of vitamin B12
T/F: ECL cells can be activated by acetylcholine or gastrin
T/F: In some cases of peptic ulcer disease, acid from the stomach erodes the D cells of the stomach preventing the brake mechanism for acid production.
these cells produce somatostatin
The gland of the stomach is known an ____ gland.
2nd messenger involved in activation of the parietal cell
this hormone acts on the G cell in the antrum of the stomach to inhibit the release of gastrin
severely delayed gastric emptying or no emptying
what activates pepsinogen?
The superficial epithelial cells along with which other cell type in the stomach act to lubricate and protect the stomach wall?
this hormone acts at the hypothalamus to suppress appetite
Peptide tyrosine-tyrosine (PYY) and glucagon like peptide (GLP1 and GLP2) ____ (stimulates/inhibits) gastric emptying
This type of drug inhibits prostaglandin related defense mechanisms within the stomach
T/F: Ghelin is released during fasting which stimulates appetite
___ are hormones released by the duodenum and cause feedback on stomach to decrease gastric emptying and secretions
These cells in the stomach are activated by the H+ions in the stomach to reduce the release of gastrin
P/D1 cells are located where?
made by the I cells of the duodenum
these cells produce histamine
Hypoglycemia ___ (increase or decreases) gastric emptying.
Which histamine receptor is found on the basolateral membrane of the parietal cell?
Cl ions are transported into the lumen of the stomach using which type of transport protein?
2 causes of peptic ulcers
these cells produce HCl and intrinsic factor
T/F: Proton pump inhibitors bind irreversibly to the H/K proton pump.
CCK ____ (promotes or inhibits) gastric emptying
T/F: The parietal cell can be activated by Acetylcholine, histamine, or gastrin.
T/F: Prilosec or Omeprazole acts at the basolateral membrane of the parietal cell.
these cells produce pepsinogen and gastric lipase
T/F: After a large meal, the alkaline tide (removal of bicarbonate from the parietal cell) causes an increase in the pH of the blood.
Nutrients in the ileum and the colon influence gastric emptying through the _____ mechanism
these cells produce gastrin
Cl ions are transported into the parietal cell using which type of transport protein?
T/F: Large volumes in the stomach increase gastric emptying
All stomach cell types are activated by the neurotransmitter (from the enteric nervous system) Acetylcholine, except which cell?
enzyme important for the production of protons and bicarbonate in the parietal cell
responsible for getting H+ ions into the lumen of the stomach
occurs due to a defiency in vitamin B12, which inhibits the body's ability to go through erythropoesis
T/F: Ileal fat increase gastric emptying.
occurs due to uncontrolled gastric emptying due to the lack of feedback inhibition by the duodenum and undigested food makes it to the colon
which two products of oxidative phosphorylation are important for the production of stomach acid.
pespinogen and HCl are released into the lumen of the stomach... where is histamine released?
T/F: Rate of gastric emptying increases with rectal and colonic distention.
T/F: An increase in pH (basicity) slows gastric emptying.
How does potassium get out of the parietal cell?
leptin is release by which type of tissue?
prilosec or omeprazole acts by inhibiting what?
H2 blockers prevent the binding of ____ to prevent the production of acid.
T/F: The stomach is the major site for digestion.
P/D1 cells release what hormone?
failure of the pyloric sphincter to relax for gastric emptying... leads to projectile vomiting
The movement of Cl into the parietal cell is coupled to the movement of which ion out of the cell?
made by the S cells of the duodenum
T/F: Tagemet and cimetidine prevent acid production by blocking H1 histamine receptors

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