Gastric Physiology

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These cells in the stomach are activated by the H+ions in the stomach to reduce the release of gastrin
2 causes of peptic ulcers
Secretin ____ (promotes or inhibits) gastric emptying
T/F: Rate of gastric emptying increases with rectal and colonic distention.
The superficial epithelial cells along with which other cell type in the stomach act to lubricate and protect the stomach wall?
this hormone acts on the G cell in the antrum of the stomach to inhibit the release of gastrin
prilosec or omeprazole acts by inhibiting what?
occurs due to a defiency in vitamin B12, which inhibits the body's ability to go through erythropoesis
Peptide tyrosine-tyrosine (PYY) and glucagon like peptide (GLP1 and GLP2) ____ (stimulates/inhibits) gastric emptying
CCK ____ (promotes or inhibits) gastric emptying
what activates pepsinogen?
All stomach cell types are activated by the neurotransmitter (from the enteric nervous system) Acetylcholine, except which cell?
essential for binding and absorption of vitamin B12
T/F: Proton pump inhibitors bind irreversibly to the H/K proton pump.
P/D1 cells release what hormone?
this hormone acts at the hypothalamus to suppress appetite
T/F: An increase in pH (basicity) slows gastric emptying.
T/F: Ghelin is released during fasting which stimulates appetite
responsible for getting H+ ions into the lumen of the stomach
which two products of oxidative phosphorylation are important for the production of stomach acid.
Which histamine receptor is found on the basolateral membrane of the parietal cell?
T/F: Tagemet and cimetidine prevent acid production by blocking H1 histamine receptors
these cells produce HCl and intrinsic factor
occurs due to uncontrolled gastric emptying due to the lack of feedback inhibition by the duodenum and undigested food makes it to the colon
pespinogen and HCl are released into the lumen of the stomach... where is histamine released?
made by the I cells of the duodenum
T/F: ECL cells can be activated by acetylcholine or gastrin
The movement of Cl into the parietal cell is coupled to the movement of which ion out of the cell?
these cells produce somatostatin
Nutrients in the ileum and the colon influence gastric emptying through the _____ mechanism
T/F: Large volumes in the stomach increase gastric emptying
failure of the pyloric sphincter to relax for gastric emptying... leads to projectile vomiting
T/F: After a large meal, the alkaline tide (removal of bicarbonate from the parietal cell) causes an increase in the pH of the blood.
___ are hormones released by the duodenum and cause feedback on stomach to decrease gastric emptying and secretions
The gland of the stomach is known an ____ gland.
enzyme important for the production of protons and bicarbonate in the parietal cell
T/F: Prilosec or Omeprazole acts at the basolateral membrane of the parietal cell.
these cells produce gastrin
severely delayed gastric emptying or no emptying
T/F: The parietal cell can be activated by Acetylcholine, histamine, or gastrin.
P/D1 cells are located where?
How does potassium get out of the parietal cell?
Hypoglycemia ___ (increase or decreases) gastric emptying.
T/F: The stomach is the major site for digestion.
2nd messenger involved in activation of the parietal cell
This type of drug inhibits prostaglandin related defense mechanisms within the stomach
T/F: Ileal fat increase gastric emptying.
made by the S cells of the duodenum
Cl ions are transported into the lumen of the stomach using which type of transport protein?
these cells produce histamine
leptin is release by which type of tissue?
T/F: In some cases of peptic ulcer disease, acid from the stomach erodes the D cells of the stomach preventing the brake mechanism for acid production.
these cells produce pepsinogen and gastric lipase
Cl ions are transported into the parietal cell using which type of transport protein?
H2 blockers prevent the binding of ____ to prevent the production of acid.

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