Gastric Physiology

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Can you name the Gastric Physiology?

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leptin is release by which type of tissue?
P/D1 cells release what hormone?
Nutrients in the ileum and the colon influence gastric emptying through the _____ mechanism
these cells produce histamine
pespinogen and HCl are released into the lumen of the stomach... where is histamine released?
these cells produce gastrin
Cl ions are transported into the parietal cell using which type of transport protein?
2nd messenger involved in activation of the parietal cell
which two products of oxidative phosphorylation are important for the production of stomach acid.
essential for binding and absorption of vitamin B12
occurs due to uncontrolled gastric emptying due to the lack of feedback inhibition by the duodenum and undigested food makes it to the colon
How does potassium get out of the parietal cell?
The superficial epithelial cells along with which other cell type in the stomach act to lubricate and protect the stomach wall?
Which histamine receptor is found on the basolateral membrane of the parietal cell?
T/F: Tagemet and cimetidine prevent acid production by blocking H1 histamine receptors
All stomach cell types are activated by the neurotransmitter (from the enteric nervous system) Acetylcholine, except which cell?
prilosec or omeprazole acts by inhibiting what?
these cells produce HCl and intrinsic factor
CCK ____ (promotes or inhibits) gastric emptying
Hypoglycemia ___ (increase or decreases) gastric emptying.
enzyme important for the production of protons and bicarbonate in the parietal cell
these cells produce somatostatin
Peptide tyrosine-tyrosine (PYY) and glucagon like peptide (GLP1 and GLP2) ____ (stimulates/inhibits) gastric emptying
T/F: In some cases of peptic ulcer disease, acid from the stomach erodes the D cells of the stomach preventing the brake mechanism for acid production.
this hormone acts on the G cell in the antrum of the stomach to inhibit the release of gastrin
T/F: Ghelin is released during fasting which stimulates appetite
occurs due to a defiency in vitamin B12, which inhibits the body's ability to go through erythropoesis
what activates pepsinogen?
Secretin ____ (promotes or inhibits) gastric emptying
severely delayed gastric emptying or no emptying
T/F: Rate of gastric emptying increases with rectal and colonic distention.
T/F: Ileal fat increase gastric emptying.
The gland of the stomach is known an ____ gland.
2 causes of peptic ulcers
H2 blockers prevent the binding of ____ to prevent the production of acid.
T/F: An increase in pH (basicity) slows gastric emptying.
T/F: ECL cells can be activated by acetylcholine or gastrin
Cl ions are transported into the lumen of the stomach using which type of transport protein?
The movement of Cl into the parietal cell is coupled to the movement of which ion out of the cell?
T/F: Prilosec or Omeprazole acts at the basolateral membrane of the parietal cell.
T/F: Proton pump inhibitors bind irreversibly to the H/K proton pump.
These cells in the stomach are activated by the H+ions in the stomach to reduce the release of gastrin
This type of drug inhibits prostaglandin related defense mechanisms within the stomach
T/F: The parietal cell can be activated by Acetylcholine, histamine, or gastrin.
___ are hormones released by the duodenum and cause feedback on stomach to decrease gastric emptying and secretions
these cells produce pepsinogen and gastric lipase
made by the S cells of the duodenum
failure of the pyloric sphincter to relax for gastric emptying... leads to projectile vomiting
responsible for getting H+ ions into the lumen of the stomach
T/F: The stomach is the major site for digestion.
P/D1 cells are located where?
T/F: Large volumes in the stomach increase gastric emptying
T/F: After a large meal, the alkaline tide (removal of bicarbonate from the parietal cell) causes an increase in the pH of the blood.
this hormone acts at the hypothalamus to suppress appetite
made by the I cells of the duodenum

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