Gastric Physiology

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T/F: After a large meal, the alkaline tide (removal of bicarbonate from the parietal cell) causes an increase in the pH of the blood.
Secretin ____ (promotes or inhibits) gastric emptying
T/F: The stomach is the major site for digestion.
Nutrients in the ileum and the colon influence gastric emptying through the _____ mechanism
The movement of Cl into the parietal cell is coupled to the movement of which ion out of the cell?
T/F: In some cases of peptic ulcer disease, acid from the stomach erodes the D cells of the stomach preventing the brake mechanism for acid production.
T/F: The parietal cell can be activated by Acetylcholine, histamine, or gastrin.
Hypoglycemia ___ (increase or decreases) gastric emptying.
T/F: Tagemet and cimetidine prevent acid production by blocking H1 histamine receptors
The gland of the stomach is known an ____ gland.
these cells produce HCl and intrinsic factor
prilosec or omeprazole acts by inhibiting what?
severely delayed gastric emptying or no emptying
leptin is release by which type of tissue?
How does potassium get out of the parietal cell?
essential for binding and absorption of vitamin B12
The superficial epithelial cells along with which other cell type in the stomach act to lubricate and protect the stomach wall?
occurs due to a defiency in vitamin B12, which inhibits the body's ability to go through erythropoesis
Cl ions are transported into the lumen of the stomach using which type of transport protein?
these cells produce gastrin
T/F: Ghelin is released during fasting which stimulates appetite
what activates pepsinogen?
2 causes of peptic ulcers
responsible for getting H+ ions into the lumen of the stomach
these cells produce pepsinogen and gastric lipase
H2 blockers prevent the binding of ____ to prevent the production of acid.
T/F: Ileal fat increase gastric emptying.
failure of the pyloric sphincter to relax for gastric emptying... leads to projectile vomiting
P/D1 cells release what hormone?
Which histamine receptor is found on the basolateral membrane of the parietal cell?
Cl ions are transported into the parietal cell using which type of transport protein?
T/F: Rate of gastric emptying increases with rectal and colonic distention.
made by the S cells of the duodenum
these cells produce histamine
P/D1 cells are located where?
Peptide tyrosine-tyrosine (PYY) and glucagon like peptide (GLP1 and GLP2) ____ (stimulates/inhibits) gastric emptying
These cells in the stomach are activated by the H+ions in the stomach to reduce the release of gastrin
CCK ____ (promotes or inhibits) gastric emptying
occurs due to uncontrolled gastric emptying due to the lack of feedback inhibition by the duodenum and undigested food makes it to the colon
T/F: Large volumes in the stomach increase gastric emptying
T/F: Prilosec or Omeprazole acts at the basolateral membrane of the parietal cell.
T/F: An increase in pH (basicity) slows gastric emptying.
which two products of oxidative phosphorylation are important for the production of stomach acid.
T/F: Proton pump inhibitors bind irreversibly to the H/K proton pump.
This type of drug inhibits prostaglandin related defense mechanisms within the stomach
2nd messenger involved in activation of the parietal cell
T/F: ECL cells can be activated by acetylcholine or gastrin
made by the I cells of the duodenum
enzyme important for the production of protons and bicarbonate in the parietal cell
___ are hormones released by the duodenum and cause feedback on stomach to decrease gastric emptying and secretions
pespinogen and HCl are released into the lumen of the stomach... where is histamine released?
this hormone acts on the G cell in the antrum of the stomach to inhibit the release of gastrin
these cells produce somatostatin
this hormone acts at the hypothalamus to suppress appetite
All stomach cell types are activated by the neurotransmitter (from the enteric nervous system) Acetylcholine, except which cell?

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Created Mar 25, 2012ReportNominate