Gastric Physiology

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Cl ions are transported into the lumen of the stomach using which type of transport protein?
H2 blockers prevent the binding of ____ to prevent the production of acid.
these cells produce histamine
prilosec or omeprazole acts by inhibiting what?
made by the I cells of the duodenum
T/F: Prilosec or Omeprazole acts at the basolateral membrane of the parietal cell.
occurs due to a defiency in vitamin B12, which inhibits the body's ability to go through erythropoesis
occurs due to uncontrolled gastric emptying due to the lack of feedback inhibition by the duodenum and undigested food makes it to the colon
CCK ____ (promotes or inhibits) gastric emptying
These cells in the stomach are activated by the H+ions in the stomach to reduce the release of gastrin
this hormone acts at the hypothalamus to suppress appetite
enzyme important for the production of protons and bicarbonate in the parietal cell
failure of the pyloric sphincter to relax for gastric emptying... leads to projectile vomiting
The movement of Cl into the parietal cell is coupled to the movement of which ion out of the cell?
these cells produce somatostatin
2nd messenger involved in activation of the parietal cell
T/F: The parietal cell can be activated by Acetylcholine, histamine, or gastrin.
2 causes of peptic ulcers
How does potassium get out of the parietal cell?
T/F: In some cases of peptic ulcer disease, acid from the stomach erodes the D cells of the stomach preventing the brake mechanism for acid production.
All stomach cell types are activated by the neurotransmitter (from the enteric nervous system) Acetylcholine, except which cell?
Nutrients in the ileum and the colon influence gastric emptying through the _____ mechanism
Which histamine receptor is found on the basolateral membrane of the parietal cell?
T/F: After a large meal, the alkaline tide (removal of bicarbonate from the parietal cell) causes an increase in the pH of the blood.
leptin is release by which type of tissue?
these cells produce HCl and intrinsic factor
essential for binding and absorption of vitamin B12
T/F: The stomach is the major site for digestion.
Secretin ____ (promotes or inhibits) gastric emptying
severely delayed gastric emptying or no emptying
Hypoglycemia ___ (increase or decreases) gastric emptying.
which two products of oxidative phosphorylation are important for the production of stomach acid.
pespinogen and HCl are released into the lumen of the stomach... where is histamine released?
this hormone acts on the G cell in the antrum of the stomach to inhibit the release of gastrin
T/F: Rate of gastric emptying increases with rectal and colonic distention.
responsible for getting H+ ions into the lumen of the stomach
T/F: Ghelin is released during fasting which stimulates appetite
what activates pepsinogen?
Peptide tyrosine-tyrosine (PYY) and glucagon like peptide (GLP1 and GLP2) ____ (stimulates/inhibits) gastric emptying
T/F: Large volumes in the stomach increase gastric emptying
The gland of the stomach is known an ____ gland.
made by the S cells of the duodenum
T/F: Proton pump inhibitors bind irreversibly to the H/K proton pump.
The superficial epithelial cells along with which other cell type in the stomach act to lubricate and protect the stomach wall?
P/D1 cells are located where?
P/D1 cells release what hormone?
these cells produce gastrin
This type of drug inhibits prostaglandin related defense mechanisms within the stomach
___ are hormones released by the duodenum and cause feedback on stomach to decrease gastric emptying and secretions
these cells produce pepsinogen and gastric lipase
T/F: ECL cells can be activated by acetylcholine or gastrin
T/F: Tagemet and cimetidine prevent acid production by blocking H1 histamine receptors
T/F: Ileal fat increase gastric emptying.
Cl ions are transported into the parietal cell using which type of transport protein?
T/F: An increase in pH (basicity) slows gastric emptying.

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