Cell Signaling

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Can you name the the HYTQ concepts?

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Ligand binding activates a G-protein (GTP-binding protein). Activated G-protein stimulates (or inhibits) an effector
release mechanism for steroid hormones
thyroid hormones bind which type of receptor? (cell surface or intracellular)
Cytosolic domain of this receptor either has intrinsic enzymatic activity or activates an associated enzyme. There is no enzyme activity without ligand.
cAMP binds the ______ subunit of protein kinase A (PKA)
these receptors bind to signaling molecules that do not diffuse into cell
catecholamine hormones bind which type of receptor? (cell surface or intracellular)
this protein inactivates G protein
this protein activates G proteins by exchanging GDP for GTP
CRE stands for what?
hydrophobic molecules generally bind to _____ receptors.
PKA catalytic subunits phosphorylate what?
term for signal that stably occupies a receptor
Phosphotyrosines recruit which adaptor protein
these receptors bind to signaling molecules that diffuse into the cell
this type of receptor protein is a channel for ion transport
these enzymes remove phosphate groups added by kinases
QuestionAnswer
release mechanism for protein or peptide hormones
which subunit of the G-protein binds GTP and GDP?
cAMP is synthesized by what?
release mechanism for catecholamine hormones
hydrophilic molecules generally bind to _____ receptors.
term for molecules that mimics signal of ligand (e.g., drug)
steroid hormones bind which type of receptor? (cell surface or intracellular)
peptide or protein hormones bind which type of receptor? (cell surface or intracellular)
G proteins are active when what molecule is bound?
release mechanism for thyroid hormones
these proteins have multiple protein binding domains and can form multi-protein complexes for signal transduction
these receptors transduce signals across the plasma membrane via changes in receptor protein conformation that lead to changes in receptor protein activity and/or receptor protein
Active RTK phosphorylates ______ residues
true or false: intracellular receptors regulate transcription.
this term describes steps that “transduce” signal binding to receptor into cellular response(s)
enzyme that phosphorylates protein target

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