Cell Signaling

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Can you name the the HYTQ concepts?

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this type of receptor protein is a channel for ion transport
these receptors transduce signals across the plasma membrane via changes in receptor protein conformation that lead to changes in receptor protein activity and/or receptor protein
these proteins have multiple protein binding domains and can form multi-protein complexes for signal transduction
these receptors bind to signaling molecules that diffuse into the cell
peptide or protein hormones bind which type of receptor? (cell surface or intracellular)
these enzymes remove phosphate groups added by kinases
release mechanism for protein or peptide hormones
term for signal that stably occupies a receptor
hydrophobic molecules generally bind to _____ receptors.
Ligand binding activates a G-protein (GTP-binding protein). Activated G-protein stimulates (or inhibits) an effector
Active RTK phosphorylates ______ residues
thyroid hormones bind which type of receptor? (cell surface or intracellular)
Phosphotyrosines recruit which adaptor protein
enzyme that phosphorylates protein target
cAMP binds the ______ subunit of protein kinase A (PKA)
release mechanism for steroid hormones
release mechanism for catecholamine hormones
QuestionAnswer
this protein inactivates G protein
true or false: intracellular receptors regulate transcription.
steroid hormones bind which type of receptor? (cell surface or intracellular)
PKA catalytic subunits phosphorylate what?
catecholamine hormones bind which type of receptor? (cell surface or intracellular)
term for molecules that mimics signal of ligand (e.g., drug)
hydrophilic molecules generally bind to _____ receptors.
release mechanism for thyroid hormones
this protein activates G proteins by exchanging GDP for GTP
Cytosolic domain of this receptor either has intrinsic enzymatic activity or activates an associated enzyme. There is no enzyme activity without ligand.
this term describes steps that “transduce” signal binding to receptor into cellular response(s)
CRE stands for what?
which subunit of the G-protein binds GTP and GDP?
G proteins are active when what molecule is bound?
these receptors bind to signaling molecules that do not diffuse into cell
cAMP is synthesized by what?

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