Science / Cell Signaling

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Can you name the the HYTQ concepts?

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QuestionAnswer
G proteins are active when what molecule is bound?
steroid hormones bind which type of receptor? (cell surface or intracellular)
these receptors bind to signaling molecules that diffuse into the cell
catecholamine hormones bind which type of receptor? (cell surface or intracellular)
PKA catalytic subunits phosphorylate what?
release mechanism for steroid hormones
this protein inactivates G protein
these receptors bind to signaling molecules that do not diffuse into cell
Cytosolic domain of this receptor either has intrinsic enzymatic activity or activates an associated enzyme. There is no enzyme activity without ligand.
this term describes steps that “transduce” signal binding to receptor into cellular response(s)
cAMP binds the ______ subunit of protein kinase A (PKA)
hydrophilic molecules generally bind to _____ receptors.
these receptors transduce signals across the plasma membrane via changes in receptor protein conformation that lead to changes in receptor protein activity and/or receptor protein
release mechanism for protein or peptide hormones
these proteins have multiple protein binding domains and can form multi-protein complexes for signal transduction
term for molecules that mimics signal of ligand (e.g., drug)
term for signal that stably occupies a receptor
QuestionAnswer
these enzymes remove phosphate groups added by kinases
release mechanism for thyroid hormones
thyroid hormones bind which type of receptor? (cell surface or intracellular)
true or false: intracellular receptors regulate transcription.
CRE stands for what?
Active RTK phosphorylates ______ residues
Ligand binding activates a G-protein (GTP-binding protein). Activated G-protein stimulates (or inhibits) an effector
this type of receptor protein is a channel for ion transport
Phosphotyrosines recruit which adaptor protein
peptide or protein hormones bind which type of receptor? (cell surface or intracellular)
release mechanism for catecholamine hormones
hydrophobic molecules generally bind to _____ receptors.
cAMP is synthesized by what?
this protein activates G proteins by exchanging GDP for GTP
enzyme that phosphorylates protein target
which subunit of the G-protein binds GTP and GDP?

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