Cell Signaling

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Can you name the the HYTQ concepts?

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this type of receptor protein is a channel for ion transport
term for signal that stably occupies a receptor
this protein activates G proteins by exchanging GDP for GTP
this term describes steps that “transduce” signal binding to receptor into cellular response(s)
term for molecules that mimics signal of ligand (e.g., drug)
thyroid hormones bind which type of receptor? (cell surface or intracellular)
release mechanism for thyroid hormones
which subunit of the G-protein binds GTP and GDP?
true or false: intracellular receptors regulate transcription.
these receptors bind to signaling molecules that do not diffuse into cell
PKA catalytic subunits phosphorylate what?
Cytosolic domain of this receptor either has intrinsic enzymatic activity or activates an associated enzyme. There is no enzyme activity without ligand.
these enzymes remove phosphate groups added by kinases
this protein inactivates G protein
cAMP binds the ______ subunit of protein kinase A (PKA)
catecholamine hormones bind which type of receptor? (cell surface or intracellular)
enzyme that phosphorylates protein target
QuestionAnswer
hydrophilic molecules generally bind to _____ receptors.
hydrophobic molecules generally bind to _____ receptors.
G proteins are active when what molecule is bound?
Ligand binding activates a G-protein (GTP-binding protein). Activated G-protein stimulates (or inhibits) an effector
peptide or protein hormones bind which type of receptor? (cell surface or intracellular)
CRE stands for what?
these proteins have multiple protein binding domains and can form multi-protein complexes for signal transduction
steroid hormones bind which type of receptor? (cell surface or intracellular)
these receptors transduce signals across the plasma membrane via changes in receptor protein conformation that lead to changes in receptor protein activity and/or receptor protein
release mechanism for catecholamine hormones
Active RTK phosphorylates ______ residues
these receptors bind to signaling molecules that diffuse into the cell
release mechanism for protein or peptide hormones
Phosphotyrosines recruit which adaptor protein
release mechanism for steroid hormones
cAMP is synthesized by what?

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