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release mechanism for steroid hormones
these enzymes remove phosphate groups added by kinases
Active RTK phosphorylates ______ residues
term for molecules that mimics signal of ligand (e.g., drug)
hydrophobic molecules generally bind to _____ receptors.
PKA catalytic subunits phosphorylate what?
these receptors bind to signaling molecules that do not diffuse into cell
release mechanism for catecholamine hormones
thyroid hormones bind which type of receptor? (cell surface or intracellular)
cAMP binds the ______ subunit of protein kinase A (PKA)
catecholamine hormones bind which type of receptor? (cell surface or intracellular)
these receptors bind to signaling molecules that diffuse into the cell
this protein inactivates G protein
peptide or protein hormones bind which type of receptor? (cell surface or intracellular)
enzyme that phosphorylates protein target
steroid hormones bind which type of receptor? (cell surface or intracellular)
release mechanism for thyroid hormones
true or false: intracellular receptors regulate transcription.
release mechanism for protein or peptide hormones
this type of receptor protein is a channel for ion transport
G proteins are active when what molecule is bound?
CRE stands for what?
these proteins have multiple protein binding domains and can form multi-protein complexes for signal transduction
this term describes steps that “transduce” signal binding to receptor into cellular response(s)
this protein activates G proteins by exchanging GDP for GTP
Cytosolic domain of this receptor either has intrinsic enzymatic activity or activates an associated enzyme. There is no enzyme activity without ligand.
Phosphotyrosines recruit which adaptor protein
term for signal that stably occupies a receptor
these receptors transduce signals across the plasma membrane via changes in receptor protein conformation that lead to changes in receptor protein activity and/or receptor protein
cAMP is synthesized by what?
hydrophilic molecules generally bind to _____ receptors.
which subunit of the G-protein binds GTP and GDP?
Ligand binding activates a G-protein (GTP-binding protein). Activated G-protein stimulates (or inhibits) an effector
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