Cell Signaling

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Can you name the the HYTQ concepts?

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enzyme that phosphorylates protein target
Phosphotyrosines recruit which adaptor protein
this protein inactivates G protein
Cytosolic domain of this receptor either has intrinsic enzymatic activity or activates an associated enzyme. There is no enzyme activity without ligand.
steroid hormones bind which type of receptor? (cell surface or intracellular)
release mechanism for catecholamine hormones
this protein activates G proteins by exchanging GDP for GTP
PKA catalytic subunits phosphorylate what?
these proteins have multiple protein binding domains and can form multi-protein complexes for signal transduction
term for signal that stably occupies a receptor
which subunit of the G-protein binds GTP and GDP?
term for molecules that mimics signal of ligand (e.g., drug)
this term describes steps that “transduce” signal binding to receptor into cellular response(s)
cAMP binds the ______ subunit of protein kinase A (PKA)
these enzymes remove phosphate groups added by kinases
true or false: intracellular receptors regulate transcription.
Active RTK phosphorylates ______ residues
QuestionAnswer
release mechanism for protein or peptide hormones
thyroid hormones bind which type of receptor? (cell surface or intracellular)
these receptors transduce signals across the plasma membrane via changes in receptor protein conformation that lead to changes in receptor protein activity and/or receptor protein
peptide or protein hormones bind which type of receptor? (cell surface or intracellular)
CRE stands for what?
cAMP is synthesized by what?
G proteins are active when what molecule is bound?
release mechanism for thyroid hormones
hydrophilic molecules generally bind to _____ receptors.
this type of receptor protein is a channel for ion transport
catecholamine hormones bind which type of receptor? (cell surface or intracellular)
these receptors bind to signaling molecules that diffuse into the cell
release mechanism for steroid hormones
these receptors bind to signaling molecules that do not diffuse into cell
hydrophobic molecules generally bind to _____ receptors.
Ligand binding activates a G-protein (GTP-binding protein). Activated G-protein stimulates (or inhibits) an effector

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