Science / Cell Signaling

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Can you name the the HYTQ concepts?

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peptide or protein hormones bind which type of receptor? (cell surface or intracellular)
enzyme that phosphorylates protein target
CRE stands for what?
thyroid hormones bind which type of receptor? (cell surface or intracellular)
hydrophobic molecules generally bind to _____ receptors.
G proteins are active when what molecule is bound?
this protein activates G proteins by exchanging GDP for GTP
these receptors bind to signaling molecules that diffuse into the cell
term for molecules that mimics signal of ligand (e.g., drug)
true or false: intracellular receptors regulate transcription.
this protein inactivates G protein
Phosphotyrosines recruit which adaptor protein
these receptors transduce signals across the plasma membrane via changes in receptor protein conformation that lead to changes in receptor protein activity and/or receptor protein
catecholamine hormones bind which type of receptor? (cell surface or intracellular)
release mechanism for steroid hormones
release mechanism for thyroid hormones
release mechanism for catecholamine hormones
QuestionAnswer
Ligand binding activates a G-protein (GTP-binding protein). Activated G-protein stimulates (or inhibits) an effector
steroid hormones bind which type of receptor? (cell surface or intracellular)
hydrophilic molecules generally bind to _____ receptors.
these proteins have multiple protein binding domains and can form multi-protein complexes for signal transduction
this term describes steps that “transduce” signal binding to receptor into cellular response(s)
PKA catalytic subunits phosphorylate what?
cAMP binds the ______ subunit of protein kinase A (PKA)
these receptors bind to signaling molecules that do not diffuse into cell
which subunit of the G-protein binds GTP and GDP?
these enzymes remove phosphate groups added by kinases
release mechanism for protein or peptide hormones
this type of receptor protein is a channel for ion transport
cAMP is synthesized by what?
term for signal that stably occupies a receptor
Active RTK phosphorylates ______ residues
Cytosolic domain of this receptor either has intrinsic enzymatic activity or activates an associated enzyme. There is no enzyme activity without ligand.

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