Russell Review

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Pulseless disease. Patients less than 50yo. Granulomatous vasculitis - classically the aortic arch.
A person with AAA is very likely to have _________ in other vessels and has an increased risk of IHD and stroke.
At 29 days and beyond, the MI is _______.
25% of AAA will rupture if it is greater than ___cm in size.
Eosinophil-rich granulomatous inflammation involving the respiratory tract and necrotizing vasculitis affecting small vessels. Associated with asthma and blood eosinophilia. AssociSmall vessel vasculitis
Troponin I needs to be greater than _____ng/mL in order to diagnose acute MI.
Segmental, thrombosing, acute and chronic inflammation of medium-sized and small arteries. Tibial and radial pulses are most often affected. Occurs almost exclusively in smokers, u
The most common form of vasculitis among elderly individuals in the United States and Europe. Therapeutic response to steroids. Unknown cause. Large vessel vasculitis
What is the clinical result of an occlusive thrombus?
Stable or Vulnerable Plaque: Thick Fibrous Cap with low Lipid content, Few inflammatory cells
Malignant hypertension is greater than 240/120 mmHg. It may develop in previously normotensive patients and usually superimposed on preexisting ________ hypertension.
Stable or Vulnerable Plaque: Thin Fibrous Cap, High lipid content, many inflammatory cells
What is the clinical result of a mural thrombus?
Diagnosis: Destroyed internal elastic lamina and giant cells. Thickened, nodular, tender segment of temporal artery.
A fixed coronary obstruction results into this symptom.
Calcification in tunica media and not in the intima.Small muscular arteries in the pelvis, neck, and breast regions can be affected.These arterial calcifications can be seen in radiographs. Medial calcific sclerosis can also be seen involving the extremities in association with autonomic neuropathy in diabetes mellitus.
Granulomatous inflammation involving the respiratory tract and necrotizing vasculitis affecting small vessels, including glomerular vessels. Associated with PR3-ANCAs. Small vessel vasculitis
40-50% of infarcts result from the occlusion of ______.
At 6h, the MI is ________.
This is the most common calcific valvular disease.Thickened cusps with dystrophic calcified plaques. Not much lipid. Not much cellular proliferation.
Necrotizing inflammation typically involving renal arteries but sparing pulmonary vessels.Medium vessel vasculitis
Hypertension leads to LVH and eventually myocardial __________.
Name a manifestation of reperfusion injury.
Arteritis with mucocutaneous lymph node syndrome, usually occurs in children. Coronary arteries can be involved with aneurysm formation and/or thrombosis.Medium vessel vasculitis
Diagnosis: Active arteritis with destruction of tunica media by chronic inflammatory infiltrates including giant cells. Cross sections of right carortid artery at autopsy showing mLarge vessel vasculitis
Necrotizing small vessel vasculitis with few or no immune deposits. Necrotizing glomerulonephritis and pulmonary capillaritis are common. Associated with MPO-ANCAs. Small vessel vasculitis
Systemic vasculitis of small or medium sized muscular arteries characterized by segmental transmural necrotizing inflammation with a predilection for branch points.Medium vessel vasculitis
At 6h-7days, the MI is ______.
At 7-28 days, the MI is _______.
Occlusion of the LAD, Circumflex artery, and RCA result into _______ infarct.
A 3-5 day old infract can have total __________ and maximal PMN infiltration.
Typically involves renal and visceral vessels but spares the pulmonary arteries. Medium vessel vasculitis
A SEVERE fixed coronary obstruction causes this condition.

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