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/ Resources of the Nervous System to Injury
Can you name the Resources of the Nervous System to Injury?
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Caused by blow to unsupported head. Most frequently in MVA.
Results from damage to the axon. The neuronal body swells due to accumulation of neurofilaments and the Nissl substance migrates peripherally.
______ is a powerful excitatory neurotransmitter, which is increased in ischemic conditions.
Third most common cause of death in the US after heart disease and cancer.
Cortical laminar necrosis is caused by generalized failure of _______
Skull fracture shears the middle meningeal artery resulting in bleeding and dissection of the dura from the inner table of the skull. The expanding mass increases ICP and may produ
Axons are stretched but not severed. Sudden deformation causes compaction of neurofilaments, loss of microtubules and an arrest of the fast axoplasmic flow.
3 Major categories of the CNS vascular disease: Reduction of blood flow, vascular obstruction causing an infarct and _______.
Lacunar infarcts are caused by arteriolosclerosis of small vessels and are common in ________
______ infarcts: small infarcts in the deeper parts of the brain and in the brain stem. Account for 20 percent of all strokes.
Symptoms last longer than 24 hours but less than 72 hours.
Areas of the brain at the junction of arterial territories.
The four types of ischemic stroke include: large vessel, small vessel, venous and ________.
_______ hemorrhage is most often caused by a ruptured berry aneurysm.
Pale or anemic infarct is caused by a vascular _________.
Neurofibrillary tangles in Alzheimer's disease and ______ bodies in Parkinson's disease are examples of neuronal changes in specific conditions.
Self-limited episode of vascular obstruction by atheromatous emboli and/or platelet and fibrin aggreagates. Disappear within 60 minutes. Symptoms are amaurosis fugax, aphasia, pare
Most common cause of an intracranial arterial occlusion is an _____ from the heart or from a more proximal arterial segment blocking a branch of the MCA.
Glycoprotein-rich concentrically laminated basophilic bodies that accumulate in astrocyte processes with age.
Ischemic ______: Infarct has a central core of irreversible ischemic necrosis. Prompt thrombolytic therapy within 3-4 hours may prevent irreversible damage.
Stroke occurs in ___ per 1000 of the general population.
Victims age range are from a few days to 5yrs. Combination of subdural hematoma, subarachnoid hemorrhage, contusions, DAI, and retinal hemorrhage.
Coup contre coup injury results from a blow on the _______ side of the head. Ventral side of the frontal and temporal lobes are common locations.
Charcot-Bouchard microaneurysm is associated with _______. Typical location is basal ganglia.
______ subdural hematoma occurs as a result of a minimal trauma and is seen in the very young and the elderly.
Viral infections may cause formation of ______ nodules.
______ aneurysms are the most common type of aneurysm of cerebral arteries.
Results from trauma that shears the veins or small arteries that traverse the space between the arachnoid and the dura.
____ malformation: Congenital, low resistance AV shunts that siphon blood from the adjacent parenchyma.
Damage caused by ischemia, inflammation, metabolic disorders (hyponatremia, respiratory acidosis), toxins, trauma and tumors can result in a breakdown of the blood-brain barrier an
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