Diuretic Agents

Random Science Quiz

Can you name the Diuretic Agents ?

Quiz not verified by Sporcle

How to Play
Used for peripheral edema, hypertension, acute hypercalcemia, hyperkalemia, acute renal failure, anion overdose
Used for hypertension, mild heart failure, nephrolithiasis, nephrogenic diabetes insipidus
Sulfonamide similar to thiazide
Toxicity: Hyperkalemic metabolic acidosis
Clinical applications: glaucoma, mountain sickness, edema with alkalosis
Only parenteral thiazide available
Inhibition of Na/K/Cl transporter in the ascending limb of Henle's loop
MOA: Inhibition of the enzyme prevents dehydration of H2CO3 and hydration of CO2
Antagonist at V1a and V2 ADH receptors. Reduces water reabsorption and increases plasma Na concentration
Popular for use with loop agents for synergistic effects
MOA: Physical osmotic effect on tissue water distribution because it is retained in the vascular compartment
Toxicity: Nausea, vomiting, headache. May enhance congestive heart failure or cause pulmonary edema.
Toxicity: Infusion site reactions
MOA: Inhibition of NaCl transporter in the distal convoluted tubule
Like spironolactone, more selective for aldosterone receptor
Pharmacologic antagonist of aldosterone
Mechanism like amiloride, much less potent, more toxic
Toxicities: Hypokalemic metabolic alkalosis, hyperuricemia, hyperglycemia, hyponatremia
Not a sulfonamide but has typical loop activity and some uricosuric action loop diuretic
Toxicities: Ototoxicity, hypovolemia, K wasting, hyperuricemia, hypomagnesemia
Toxicities: metabolic acidosis, renal stones, hyperammonemia in cirrhotics
MOA: Blocks epithelial sodium channels in collecting tubules
Toxicity: Hyperkalemia, gynecomastia
Reduces reabsorption of HCO3- in the kidney causing self limited diuresis

Friend Scores

  Player Best Score Plays Last Played
You You haven't played this game yet.

You Might Also Like...


Created Feb 12, 2011ReportNominate
Tags:agent, diuretic