| x | x | x |
|---|
| Efficacy similar to Methotrexate. Inhibits dihydroorate dehydrogenase. Stops B cell function and T cell proliferation. Toxicity- Diarrhea (25%) and elevated liver enzymes | |
| TNF-alpha receptors linked to IgG1. Given SC | |
| Used for ulcerative colitis. | |
| Metal chelator used for Wilson's disease and copper poisoning | |
| Antimalarial. Toxicity- GI distress, ototoxicity, headache, myopathy, and neuropathy. | |
| Oral Gold Salt | |
| Suppress IL-2 and TNF-alpha. Used for transplant rejection. Toxicity- hyperkalemia, hypertension, and may be teratogenic and oncogenic | |
| | x | x | x |
|---|
| DMARD of first choice. Folic acid analogue. Toxicity - inhibiting all fast growing cells and hepatotoxicity | |
| Binds CD20 on B cells. B cell depletion | |
| Monoclonal against TNF-alpha. IV weekly | |
| Monoclonal against TNF-alpha. IV monthly | |
| Endogenous ligand for CTLA4. Prevents APC from activating T cells. | |
| Gold salt given IV/IM. Toxicity- dermatitis (15-20%), cytopenias, proteinuria, diarrhea | |
| Inhibits inosinic acid synthesis and inhibits B and T cell function. Bone marrow toxicity, oncogenesis, teratogenesis, and increased infection risk. | |
|
Periodic Table
Planets from the Sun
Digits of Pi
