| Definition | Terms |
| P50 of fetal Hb (mmHg) | |
| These help to stabilize the folding and unfolding intermediates | |
| Tryptophan (Essential or Non-Essential) | |
| ________________ regions tend to be structural and functional regions between homologous proteins. | |
| Failure of the lungs to eliminate CO2 as fast as it is produced is called | |
| When oxygen is not bound to the heme iron it is in which form? (T or R) | |
| Adult Hb shifts the O2 binding curve to the... | |
| When blood pH is above _________ it is considered alkalosis | |
| This type of breathing can cause alkalosis. | |
| At high pH the amino acid is ______________ at both the amino and carboxyl groups. | |
| Chemical that minimized the change in pH of a solution by binding excess H+ while also being able to release H+ if pH is low | |
| Glutamic Acid/Glutamate (Essential or Non-Essential) | |
| Co-chaperson for Hsp60 | |
| Glycine (Essential or Non-Essential) | |
| Which secondary structure is more stable? | |
| Co-chaperone for Hsp70 | |
| The concept that upon each binding of an O2 to a heme subunit causes a higher affinity for the next O2 binding is called... | |
| Chemical that 'locks' Hb in T-state forcing the release of oxygen | |
| Alpha helicies are generally ______ resides long with _______ amino acids per turn | |
| Enzyme that assists in the formation, rearrangement and breaking of disulfide bonds | |
| Deoxygenated Hb has a higher affinity for H+ ions | |
| High serum carbon monoxide concentration shifts O2 binding curve | |
| The lid structure of the E. coli chaperonin system is | |
| Lysine (Essential or Non-Essential) | |
| Less toxic Hsp90 inhibitor that blocks ATP binding pocket | |
| Removing CO2 from the blood by the lungs helps to ____________ pH | |
| Protein folding is primarily driven by | |
| At low pH the amino acid is ______________ at both the amino and carboxyl groups. | |
| Isoleucine (Essential or Non-Essential) | |
| Threonine (Essential or Non-Essential) | |
| Low temperature shifts the O2 binding curve.... | |