| Question | Answer |
| In what year is Mass Effect set? | |
| What is the name of the substance that can be manipulated into a Mass Effect Field? | |
| Which player class allows the use of both Tech and Biotic abilities? | |
| In the Sole Survivor scenario, Shepard's entire unit was slaughtered on which planet? | |
| In the Earthborn scenario, Shepard was a member of which gang? | |
| In the Spacer scenario, Shepard's mother serves on which ship ? | |
| What planet is Commander Shepard heading to at the beginning of the game? | |
| What is the name of the Turian Spectre who accompanies Shepard on this mission? | |
| The beacon on the planet was thought to be an artifact of which ancient race? | |
| Which member of Shepard's squad was killed on this mission? | |
| What do the Alliance soldiers call the spikes that the Geth use to create Husks? | |
| What material can all weapons, armor and upgrades be broken down into? | |
| What is the name of Commander Shepard's ship? | |
| Who is the Chief Medical Officer aboard Shepard's ship? | |
| What disease does Joker suffer from? | |
| What is the name of the Human Ambassador on the Citadel? | |
| What is the name of the Virtual Intelligence program that provides information on the Citadel? | |
| In what area of the Citadel was the Hanar preaching about the 'Enkindlers'? | |
| Who is the head of Citadel Security? | |
| What is the name of the Asari Consort? | |
| The two individuals who were trying to scan the keepers were Jahleed and... | |
| What was the biological weapon that was used on the Krogans? | |
| What was the name of Dr. Chloe Michel's former colleague who was blackmailing her? | |
| What is the name of the Volus information dealer on the Citadel? | |
| What is the name of the club that Harkin could be found in? | |
| Who is the owner of Flux? | |
| What is the game that can be played at Flux? | |