| Cause of Death | Character |
| Vampire whose head was taken off by Elijah | |
| Vampire who got bit by a werewolf then was later staked by Damon | |
| Human killed by his son, Stefan | |
| Original vampire who was killed by a dagger numerous times | |
| Witch who was caught on fire by Damon after trying to remove the dagger from Elijah | |
| Witch whose neck was snapped by Stefan after Katherine bit him | |
| Vampire who lets herself burn to death under the compulsion of Klaus | |
| Sacrificed himself to save his daughter from becoming a vampire | |
| Werewolf who was killed as a part of Klaus's sacrifice | |
| Turned into a vampire and later killed by Klaus as a part of his sacrifice | |
| Witch whose neck was snapped by Damon after Klaus's sacrifice | |
| Committed suicide in front of Damon after being compelled by Stefan | |
| Original vampire daggered by Klaus, Elena, and then by Klaus again | |
| Original vampire/vampire hunter killed by Klaus after working with Elena and Damon to kill Klaus | |