| Question | Answer |
| What does Derek give Meredith as a present after the domino surgery? | |
| What 'club' do Meredith and Mark say they belong to? | |
| What adjective does Ellis Grey say she wanted Meredith to be? | |
| What colour were the panties that Addison tacked to the board? | |
| What does Richard change about himself to woo 'the ladies'? | |
| What does Meredith win in the residents competition? | |
| What does Addison call her goodluck coffee? | |
| What does George call his and Lexie's appartment? | |
| What is George's special administrative position? | |
| How many sisters does Derek Shepherd have? | |
| What did Izzie's mother used to call her? | |
| What was Izzie's model name? | |
| Which Grey's Anatomy character has a PhD? | |
| What is Derek's middle name? | |
| How many (main) characters have been pregnant at some point? | |
| Who is Derek's favourite band? | |
| What is Izzie's daughter's name? | |
| How many people has George slept with on the show? | |
| How much money did Denny leave Izzie in his will? | |
| What was the first symptom of Susan Grey's fatal illness? | |
| What colour shirt was Derek wearing when he first met Meredith? | |
| What is Meredith and Lexie's sister named? | |
| What did Denny Duquette ultimately die of? | |
| What was the name of Derek and Meredith's dog? | |
| How many people have been given Mc-Titles? | |
| What does Cristina call Alex's brother upon meeting him? | |
| What food-eating competition does Cristina win? | |
| What does the sign that Meredith and Cristina place on the trailer door say? | |
| How many (main) characters have at some point lived in Meredith's house? | |