Can you name the Drug Sedative/Hypnotic? by VernBMarty

Class	generic name	Trade. Use or Misc info (Tox)
BDZ General		BenzOften, open chan more often. Anxiety, periop sedation. Tox: (lethargy, somnia, stupor, antero amnesia, tolerance/depnd, CNS dprsn)
BDZ		Xanax. Gen Anxiety
BDZ		Librium, Librax. Tx: Physcl Depdnc W/D
BDZ		Klonopin. Gen Anxiety, best Chr Sz, BPD.
BDZ		Valium. Tx: Sz, Physcl Depdnc
BDZ		Rohypnol.
BDZ		Ativan. Does not form metabolites. Tx: Sz, BPD, Phys Depdnc
BDZ		Short acting, rapid onset, anesthetsia
BDZ		Does not form metabolites (skips Phase I)
BDZ		Restoril. Sleep, Hypnotic.
BDZ		Halcion. Sleep. (lethargy, somnia, stupor, antero amnesia, tolerance/depnd, CNS dprsn)
BDZ Antag		Romazicon. Caution: Reserve ICO Stim+BDZ OD, & it will block Tx of SZ if BDZ depdnt Pt
Barbituate General		Opens GABA Cl- chann longer, INDUCE CYP 450 & ALA Synthase. Less selective than BDZ. GABA-ergic at high conc. Block Na and Glu receptrs. (CNS Deprsn, OD risk, porphyria)
Barbituate		Luminal. LA. CYP450 INDUCER. 2nd line Sz (same as BDZ + inc ALA synthase LT porphyria, rare-hematotox)
Barbituate		SA. CYP450 INDUCER. (same as BDZ + inc ALA synthase LT porphyria)

Class	generic name	Trade. Use or Misc info (Tox)
Barbituate		Pentothal. short acting (SA). CYP450 INDUCER. Very lipophil, love brain. Gen Anesth. (same as BDZ + inc ALA synthase LT porphyria)
Mood Stab		Tegretol. Acute BPD Mania. Focal Sz. CYP450 INDUCER, (diplopia, ataxia, aplastic anemia, GI upset, teratogen)
Mood Stab		Lamictal. M/c bipolar. Acute BPD mania. CYP450 INDUCER, (Rash, ataxia, GI upset, diplopia, teratogen, Stevens Johnson Syn)
Mood Stab		Eskalith. Inhibit PIP2, NE and Dop release. Renal Exc. No Diuretics or NSAIDs! (polys, wt gain, acne, diarrhea, teratogen)
Mood Stab		Depakote. Acute and Maint BPD. Abscense Sz.. Pri choice > Lithium. (N/V, Wt Gain, alopecia, abd pain, hep tox, teratogen, rare-fulminant hep)
AAP		Zyprexa. Antag D2, 5HT2, alpha. BPD Dprsn w/ Prozac. (Wt gain, DM2, LQT, hyperprolactinemia, HL, confusion)
AAP		Seroquel. Antag D2, 5HT2, alpha. BPD Dprsn. (Wt gain, DM2, LQT, hyperprolactinemia, HL, confusion)
AE		Zarontin. Abscense Sz. (N, anorexia, drows, rash)
AE		Keppra. Sz. Neuopath pain, Tourette. (psycho, hairloss, sensory, depressn, irratibilty)
AE		Dilantin. Sz. Give slowly. (nystagmus, ataxia, drows, gingival hyperplasia, endocrine: hirsutism, osteomal, DI, hyperglycemia)
Alcohol		Rapid onset hypnotic in Old and sedation in kids. Tx Insomia, presurg Anx)
Alcohol		Tx of methanol & EthGlycol OD. (CNS Deprs, delirium)
NBDZ		Sonata. t1/2 1 hr. CYP450 (same BDZ)
NBDZ		Ambien. t1/2 3 hr. CYP450 (same BDZ + somnambulance)
NBDZ		Lunesta. t1/2 6 hr. CYP450 (same BDZ)

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