| Event | Year |
| Tupac Shakur is gunned down in Las Vegas | |
| Vanessa Williams becomes the first African-American 'Miss America' | |
| TV ads first appear in support of presidential campaigns, with 'I Like Ike' proving successful | |
| 'Steamboat Willie' (starring Mickey Mouse) is released | |
| Geraldine Ferraro becomes the first female candidate for Vice President | |
| The NAACP is symbollically founded on the centennial of Abraham Lincoln's birth | |
| The Chicago Cubs win the second of two back-to-back World Series titles | |
| New York City begins subway service | |
| In Pennsylvania, the US's first nuclear power plant opens | |
| Four LAPD officers are acquitted in the Rodney King case, setting off a riot | |
| Lyndon Johnson signs the Civil Rights Act into law | |
| John F. Kennedy is assassinated in Dallas | |
| In Roe v. Wade, the Supreme Court declares abortion legal | |
| Upton Sinclair publishes 'The Jungle,' resulting in widespread food safety reforms | |
| Erwin Rommel defeats US forces in the Battle of Kasserine Pass | |
| Martin Luther King, Jr., is assassinated in Memphis | |
| 'Time' magazine hits shelves for the first time | |
| The Lincoln Memorial is dedicated | |
| Frankin Roosevelt is elected to an unprecedented third term as president | |
| Neil Armstrong becomes the first human to set foot on the moon | |
| Jesse 'The Body' Ventura is elected Governor of Minnesota | |
| The Wright Flyer takes off for the first time at Kitty Hawk, NC | |
| The 21st Ammendment is ratified, repealing Prohibition | |
| New Mexico and Arizona become the 47th and 48th states, respectively | |
| Dwight Eisenhower gives the go-ahead order for the D-Day Invasion | |
| Babe Ruth hits his first home run | |
| Apollo 13 undergoes a crisis in space when an oxygen tank explodes | |
| The 'Morris Worm' becomes the first computer worm to spread virally via the Internet | |
| Charles Schulz's 'Peanuts' first appears in newspapers | |
| Pearl Harbor is bombed | |
| The Dow Jones Industrial Average closes above 10,000 for the first time | |
| Theodore Roosevelt first becomes president | |
| Macy's stages its first annual Thanksgiving Day Parade | |
| The legendary Route 66 is formally established | |